Keywords: Kir6.2; KATP channels; Emotional behavior; Anxiety; Monoamine; Tryptophan hydroxylase;
مقالات ISI (ترجمه نشده)
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Keywords: SUR2; Kir6.1; Kir6.2; Cantu; Vasodilation; Edema; Arrhythmia;
NFκB mediated elevation of KCNJ11 promotes tumor progression of hepatocellular carcinoma through interaction of lactate dehydrogenase A
Keywords: Kir6.2; Lactate dehydrogenase A; Inwardly rectifying subfamily; Hepatocellular carcinoma;
Expression, purification, and electrophysiological characterization of a recombinant, fluorescent Kir6.2 in mammalian cells
Keywords: Kir6.2; Recombinant ion channel; Reconstitution; Black lipid membrane; Electrophysiology;
Chronic palmitic acid-induced lipotoxicity correlates with defective trafficking of ATP sensitive potassium channels in pancreatic β cells
Keywords: KATP channel; ATP sensitive potassium; SUR1; sulfonylurea receptor 1; INS-1 cells; rat insulinoma; Kir6.2; inwardly rectifying potassium channel 6.2; GB; glibenclamide; DZ; diazoxide; PA; palmitic acid; OA; oleic acid; Tolb; tolbutamide; iNOS; inducible N
Original articleThe mechano-sensitivity of cardiac ATP-sensitive potassium channels is mediated by intrinsic MgATPase activity
Keywords: ATP-sensitive potassium channels; KATP channels; Kir6.2; SUR2A; SUR1; Stretch; Mechanosensitivity; MgATPase activity;
Mechanisms of the amplifying pathway of insulin secretion in the β cell
Keywords: ABCC8; ATP binding cassette subfamily C member 8; ADCY5; adenylyl cyclase type 5; AICAR; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; DPP-IV; dipeptidyl peptidase 4; G6PD; glucose-6-phosphate dehydrogenase; GDH; glutamate dehydrogenase; GIP; gast
Dopamine midbrain neurons in health and Parkinson's disease: Emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels
Keywords: D2-AR; D2-autoreceptor; DA; dopamine; DBS; deep brain stimulation; DHPs; dihydropyridines; ER; endoplasmic reticulum; ETC; electron transfer chain; K-ATPs; ATP-sensitive potassium channels; LC; locus coeruleus; LTCCs; L-type calcium channels; mNOS; mitoch
ABCC8 genetic variants and risk of diabetes mellitus
Keywords: KATP; ATP-sensitive K+; CALPN10; calpain 10; PRKACG; cAMP-dependent protein kinase catalytic subunit G; DM; diabetes mellitus; ENSA; endosulfine alpha; FOXA2; forkhead box A2; GWAS; genome-wide association studies; GDM; gestational diabetes mellitus; HVA;
Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels
Keywords: PIP2; phosphatidylinositol 4,5-bisphosphate; KATP channels; ATP-sensitive K+ channels; SUR; sulfonylurea receptor; Syn-1A; syntaxin-1A; PM; plasma membrane; FRET; fluorescence resonance energy transfer; Kir; potassium inward rectifiers; PLC; phospholipase
Short CommunicationCo-inheritance of two ABCC8 mutations causing an unresponsive congenital hyperinsulinism: Clinical and functional characterization of two novel ABCC8 mutations
Keywords: CHI; congenital hyperinsulinism; KATP; ATP-sensitive K(+); SUR1; sulfonylurea receptor; Kir6.2; inwardly rectifying potassium channel; Congenital hyperinsulinism; Mutation; ABCC8; Functional study;
Parametrisation of the free energy of ATP binding to wild-type and mutant Kir6.2 potassium channels
Keywords: ATP-sensitive potassium channel; Kir6.2; Molecular dynamics; Homology modelling; Linear Interaction Energy (LIE) method;
Association of KCNJ11 E23K gene polymorphism with hypoglycemia in sulfonylurea-treated Type 2 diabetic patients
Keywords: KCNJ11; Kir6.2; E23K polymorphism; Sulfonylureas; Hypoglycemia; Type 2 diabetes; Pharmacogenetics;
Effects of Single Nucleotide Polymorphisms in KATP Channel Genes on Type 2 Diabetes in a Turkish Population
Keywords: Type 2DM; KATP channel; SUR1; Kir6.2; Single nucleotide polymorphisms;
KATP channel mutations in congenital hyperinsulinism
Keywords: SUR1; Kir6.2; KATP channel; Congenital hyperinsulinism; Hyperinsulinemic hypoglycemia; Diazoxide-responsiveness
Syntaxin-1A inhibits KATP channels by interacting with specific conserved motifs within sulfonylurea receptor 2A
Keywords: Syntaxin-1A; SNARE; ATP-sensitive potassium channel; SUR2A; Kir6.2
Cardiac sarcolemmal KATP channels: Latest twists in a questing tale!
Keywords: ATP channel; Kir6.2; SUR1; Glibenclamide; Diazoxide; Pinacidil; mitoKATP;
Quaternary structure of KATP channel SUR2A nucleotide binding domains resolved by synchrotron radiation X-ray scattering
Keywords: ATP-sensitive K+ channel; Kir6.2; SUR2A; Small-angle X-ray scattering; Mutation; Structure
Diabetes neonatal: implicaciones de la genética en el tratamiento
Keywords: Diabetes neonatal; Kir6.2; SulfonilureasNeonatal diabetes; Kir6.2; Sulfonylurea
INGAP-PP up-regulates the expression of genes and proteins related to K+ATP channels and ameliorates Ca2+ handling in cultured adult rat islets
Keywords: Cytoplasmic Ca2+; Cultured pancreatic islets; Foxa2; Insulin secretion; INGAP-PP; K+ATP channels; Kir6.2; SUR1
Insuline et fonction pancréatique
Keywords: Glucokinase; Kir6.2; Incrétines; Hétérogénéité des cellules β; Voie amplificatrice;
Neonatal hyperglycaemia and abnormal development of the pancreas
Keywords: neonatal diabetes mellitus; pancreatic insufficiency; β-cell function; insulin secretion; insulin therapy; newborns; genetic mechanisms; imprinting; diabetes mellitus genes; potassium channel; SUR1; kir6.2
Gating of the ATP-sensitive K+ channel by a pore-lining phenylalanine residue
Keywords: Kir6.2; KATP channel; Gating; Hydrophobicity; Steric hindrance
Behavioral phenotyping of mice lacking the KATP channel subunit Kir6.2
Keywords: Kir6.2; KATP channels; Knockout mice; Motor activity; Species-typical behavior; Anxiety
Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine
Keywords: Kir6.2; Proteasome; Aprindine;
A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K+ channels
Keywords: ATP-sensitive K+ channel; Kir6.2; Sulfonylurea receptor; ABC protein; Nucleotide-binding domain; Nicorandil; K+ channel opener;
Cardiac KATP channels in health and disease
Keywords: ATP-sensitive K+ channel; Kir6.2; SUR2A; Ischemia; Flight-or-fight; Heart failure; Stress; Calcium; KATP channel; ATP-sensitive potassium channel; Kir6.2-knockout; Kir6.2 gene knockout mouse; MEF2; myocyte enhancer factor 2; SUR; sulfonylurea receptor;
Congenital hyperinsulinism
Keywords: Congenital hyperinsulinism; Hypoglycaemia; Insulin; Glucose; Potassium channels; SUR1; KIR6.2;
Function and distribution of the SUR isoforms and splice variants
Keywords: KATP channels; SUR isoforms; Splice variant; Gene; ABC proteins; ATP-binding cassette transporter proteins; KATP; ATP-sensitive potassium channel; KIR; K+ inward rectifier family; KIR6.x; the pore-forming subunit of the KATP channel; KIR6.1; the pore-form
ATP-sensitive K+ channel channel/enzyme multimer: Metabolic gating in the heart
Keywords: KATP channel; Kir6.2; SUR2A; Eneregetics; Creatine kinase; Adenylate kinase; Glycolysis; Sulfonylurea receptor; Phosphotransfer; Nucleotide; ATP-binding cassette; Action potential; Heart failure; Potassium channel opener; Knock-out;
KATP channel therapeutics at the bedside
Keywords: ATP-sensitive K+ channels; Kir6.2; Kir6.1; SUR1; SUR2; Angina pectoris; Hypertension; Ischemic heart disease; Peripheral vascular disease; Asthma; Alopecia; Impotence; Neuroprotection;