Keywords: بیماری آلزایمر در شروع زودرس; Polygenic risk score; Sporadic late-onset Alzheimer's disease; Early-onset Alzheimer's disease; Early-onset autosomal dominant; Late-onset Alzheimer's disease; Dominantly inherited Alzheimer network; APOE; APP; PSEN1; PSEN2; Genetic architecture; Area und
مقالات ISI بیماری آلزایمر در شروع زودرس (ترجمه نشده)
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Keywords: بیماری آلزایمر در شروع زودرس; Home research study visits; Research clinic study visits; Missing data; Bias; Prospective studies; Cohort studies; Longitudinal studies; Inference; Late-onset Alzheimer's disease; Genetics; Genome-wide studies; Genome-wide association studies; Ascertainme
Keywords: بیماری آلزایمر در شروع زودرس; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease; Cognition; Memory; Semantic memory; Neuropsychological tests;
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; Genetics; Type 2 diabetes mellitus; Genotype risk score; Mediated pleiotropy; Environmental;
Keywords: بیماری آلزایمر در شروع زودرس; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease; MRI; Diffusion tensor MRI; White matter damage;
The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes
Keywords: بیماری آلزایمر در شروع زودرس; TOMM40 poly-T; APOE; Late-onset Alzheimer's disease; Cognitive performance; Brain imaging;
sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling
Keywords: بیماری آلزایمر در شروع زودرس; Aβ; amyloid β; AD; Alzheimer's disease; ADAM; A Disintegrin And Metalloproteinase (α-secretase); APP; amyloid precursor protein; AMPA-R; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; BACE; β-site of APP cleavage enzyme (β-secretase)
A rare variant in MLKL confers susceptibility to ApoE É4-negative Alzheimer's disease in Hong Kong Chinese population
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; ApoE É4-negative; Whole exome sequencing; MLKL;
An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; 19q13.32; APOE; eQTL; Tau level;
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; Microglia; Neuroinflammation; Beta-amyloid; Neurodegeneration; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease;
Altered gene expression in late-onset Alzheimer's disease due to SNPs within 3â²UTR microRNA response elements
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; MicroRNA response elements; miRNA; Gene expression; SNPs;
Featured ArticleGenome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; Non-Hispanic white; Late-onset Alzheimer's disease; Linkage; High penetrance; Identity by descent; Familial; Genetics;
Featured ArticleLinkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; Caribbean Hispanic families; Late-onset Alzheimer's disease; Linkage analysis; Joint linkage and association;
Meta-analysis of the association between CR1 polymorphisms and risk of late-onset Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; CR1; Late-onset Alzheimer's disease; Polymorphisms; Meta-analysis
Featured ArticleTwo rare AKAP9 variants are associated with Alzheimer's disease in African Americans
Keywords: بیماری آلزایمر در شروع زودرس; Whole-exome sequencing; Late-onset Alzheimer's disease; Rare variant; Genetic association; African American; AKAP9;
Blockage of CR1 prevents activation of rodent microglia
Keywords: بیماری آلزایمر در شروع زودرس; Aβ; amyloid beta; AD; Alzheimer's disease; Apo; apocynin; APP; amyloid precursor protein; CGC; cerebellar granule cells; CR1; complement receptor 1; DIV; days in vitro; DHE; dihydroethidium; D-MEM; Dulbecco's modified eagle medium; EA; ethacrynic acid; E
GSTM1 null genotype as risk factor for late-onset Alzheimer's disease in Italian patients
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; Glutatione S-transferases; Genetic polymorphism; Detoxification enzymes;
GSTO1*E155del polymorphism associated with increased risk for late-onset Alzheimer's disease: Association hypothesis for an uncommon genetic variant
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; Glutatione S-transferases; GST Omega class; Uncommon genetic variants; Italian population;
Complement receptor 1 (CR1) and Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; AD; Alzheimer's disease; Aβ; amyloid-beta; ApoE; apolipoprotein E; BBB; blood-brain barrier; CCP; complement-control proteins; CFH; complement factor H; C3; complement factor 3; CR1; complement receptor 1; CSF; cerebrospinal fluid; E-CR1; erythrocyte c
Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults
Keywords: بیماری آلزایمر در شروع زودرس; Apolipoprotein E; Late-onset Alzheimer's disease; Magnetic resonance imaging; Voxel-based morphometry; Multivariate analysis; Gray matter volume;
Different β-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity
Keywords: بیماری آلزایمر در شروع زودرس; Alzheimer's disease; Early-onset Alzheimer's disease; Late-onset Alzheimer's disease; Age; Autopsy brain; β-amyloid oligomers; Fibrillar β-amyloid; Choline acetyltransferase activity; Nicotinic acetylcholine receptors; [3H]nicotine binding; [3H]PIB bind
Epigenetics in neurodegeneration: A new layer of complexity
Keywords: بیماری آلزایمر در شروع زودرس; AD; Alzheimer's disease; PD; Parkinson's disease; Aβ; amyloid-β; SN; substantia nigra; APP; amyloid precursor protein; EOAD; early-onset Alzheimer's disease; LOAD; late-onset Alzheimer's disease; SNP; several single nucleotide polymorphisms; MZ; monozyg
Association of polymorphism of DNA repair gene XRCC1 with sporadic late-onset Alzheimer's disease and age of onset in elderly Han Chinese
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; X-ray repair cross-complementing group 1 (XRCC1); Apolipoprotein E; Polymorphism; Chinese
Meta-analysis of linkage studies for Alzheimer's disease—A web resource
Keywords: بیماری آلزایمر در شروع زودرس; Alzheimer's disease; Late-onset Alzheimer's disease; Linkage (genetics); Meta-analysis; Genome search meta-analysis
Age-related influence of the HDL receptor SR-BI on synaptic plasticity and cognition
Keywords: بیماری آلزایمر در شروع زودرس; Cholesterol; HDL; α-Tocopherol; Scavenger receptors; Lipid metabolism; Atherosclerosis; Late-onset Alzheimer's disease; LTP; Recognition memory; Spatial memory
Endophenotypes in normal brain morphology and Alzheimer's disease: a review
Keywords: بیماری آلزایمر در شروع زودرس; endophenotypes; brain morphology; Alzheimer's disease; cognitive impairment; ADAS-Cog; Alzheimer Disease Assessment Scale-Cognitive subscale; APOE; apolipoprotein E; CCMS; Cache County Study of Memory in Aging; CIND; cognitive impairment no dementia; CR;
The association of mitochondrial aldehyde dehydrogenase gene (ALDH2) polymorphism with susceptibility to late-onset Alzheimer's disease in Chinese
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; Mitochondrial aldehyde dehydrogenase (ALDH2); Apolipoprotein E; Polymorphism; Chinese
Genetic analysis of tumor necrosis factor-α (TNF-α) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; APOE ε4;TNF-α; STH; Case-control study; Chinese
Impact of the matrix metalloproteinase MMP-3 on dementia
Keywords: بیماری آلزایمر در شروع زودرس; Alzheimer's disease; Late-onset Alzheimer's disease; β-Amyloid peptide; Clearance; Matrix metalloproteinase; Genetic polymorphism; Genetic association study
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease
Keywords: بیماری آلزایمر در شروع زودرس; Late-onset Alzheimer's disease; PTEN; GSK3; Polymorphism; Genetics; DNA pooling;