دانلود مقالات ISI درباره LBD، دامنه اتصال لیگاند + ترجمه فارسی

استفاده از رویکردهای مدل سازی محاسباتی در بررسی تعاملات اتصال از ترکیبات با گیرنده های استروژن انسان

Use of computational modeling approaches in studying the binding interactions of compounds with human estrogen receptors

Keywords: LBD، دامنه اتصال لیگاند; CoMFA, comparative molecular field analysis; CoMSIA, comparative molecular similarity indices analysis; E1, estrone; E2, 17β-estradiol; EDC, endocrine disrupting chemical; ER, estrogen receptor; H12, Helix 12; LBD, ligand binding domain; OH-PBDE, hydroxyl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Syringaresinol induces mitochondrial biogenesis through activation of PPARβ pathway in skeletal muscle cells

Keywords: LBD، دامنه اتصال لیگاند; PPAR, peroxisome proliferator-activated receptor; Syr, syringaresinol; LBD, ligand binding domain; CPT1, carnitine palmitoyltransferase 1; UCP2, uncoupling protein 2; ITC, isothermal titration calorimetry; TR-FRET, time-resolved fluorescence resonance ene

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Liver X Receptor (LXR) in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, mRNA tissue expression and transcriptional regulation by insulin in vivo and in vitro

Keywords: LBD، دامنه اتصال لیگاند; AF, activation function; BW, body weight; DBD, DNA binding domain; LBD, ligand binding domain; LXR, liver X receptor; LXRE, LXR responsive elements; ORF, open reading frame; SEM, standard error of means; UTR, untranslated regionsPelteobagrus fulvidraco; l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Helix 8 of the ligand binding domain of the glucocorticoid receptor (GR) is essential for ligand binding

Keywords: LBD، دامنه اتصال لیگاند; GR, glucocorticoid receptor; ER, estrogen receptor; LBD, ligand binding domain; EGFP, enhanced green fluorescent protein; DMEM, Dulbecco's modified Eagle medium; TBST, Tris-buffered saline/0.1% Tween 20; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; BS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175

Keywords: LBD، دامنه اتصال لیگاند; PPAR; Bioisosterism; Docking; Gene expression studyMS, metabolic syndrome; CVD, cardiovascular disease; FFAs, free fatty acids; LBD, ligand binding domain; MOIMM, [(methyloxy)imino]methyl moiety; 3D-QSAR, three-dimensional quantitative structure activity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a naturally occurring retinoid X receptor agonist from Brazilian green propolis

Keywords: LBD، دامنه اتصال لیگاند; BGP, Brazilian green propolis; FBS, fetal bovine serum; HEK, human embryonic kidney; LBD, ligand binding domain; LXR, liver X receptor; NR, nuclear receptor; PPAR, peroxisome proliferator-activated receptor; RAR, retinoic acid receptor; RXR, retinoid X re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Annotation of the Daphnia magna nuclear receptors: Comparison to Daphnia pulex

Keywords: LBD، دامنه اتصال لیگاند; NR, nuclear receptor; CDD, conserved domain database; DBD, DNA binding Domain; LBD, Ligand binding Domain; Pfam, Protein family; ML, Maximum Likelihood; EcR, Ecdysone Receptor; KNR, Knirp; THRL, Thyroid hormone receptor-like; RARL, Retinoid Acid Receptor-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor α

Keywords: LBD، دامنه اتصال لیگاند; PPARα, peroxisome proliferator-activated receptor alpha; DBD, DNA binding domain; LBD, ligand binding domain; RXRα, retinoid X receptor alpha; LCFA, long-chain fatty acids; LCFA-CoA, long-chain fatty acyl-CoA; mPPARα, mouse PPARα; hPPARα, human PPARα; F27

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide derivatives as new RORγ inhibitors using virtual screening, synthesis and biological evaluation

Keywords: LBD، دامنه اتصال لیگاند; RORγ inhibitor; Th17 cell differentiation; Virtual screening; Nuclear hormone receptorRORγ, retinoic acid receptor-related orphan receptor γ; LBD, ligand binding domain; LBP, ligand binding pocket; IC50, 50% inhibitory concentration; SAR, structure activi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Homodimerization propensity of the intrinsically disordered N-terminal domain of Ultraspiracle from Aedes aegypti

Keywords: LBD، دامنه اتصال لیگاند; NTD, N-terminal domain; DBD, DNA binding domain; LBD, ligand binding domain; 20E, 20-hydroxyecdysone; EcR, ecdysone receptor; RXR, retinoid X receptor; Usp, Ultraspiracle; HR38, hormone receptor 38; IDP, intrinsically disordered protein; EcR-NTD, N-termin

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Estrogen receptors alpha (ERα) and beta (ERβ): Subtype-selective ligands and clinical potential

Keywords: LBD، دامنه اتصال لیگاند; ER, estrogen receptor; ERα, estrogen receptor subtype alpha; ERβ, estrogen receptor subtype beta; LBD, ligand binding domain; RBA, relative binding affinityEstrogen receptor subtype α; Estrogen receptor subtype β; Modulators; Agonists; Antagonists; Therap

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Enteral calcium infusion used successfully as treatment for a patient with hereditary vitamin D resistant rickets (HVDRR) without alopecia: A novel mutation

Keywords: LBD، دامنه اتصال لیگاند; HVDRR, Hereditary vitamin D resistant rickets; VDR, Vitamin D receptor; DBD, DNA binding domain; LBD, Ligand binding domain; PTH, Parathyroid hormone; RXR, Retinoid X receptor; PICC, Peripherally inserted central catheter; IV, IntravenousHereditary vitami

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Role of Rev-erbα domains for transactivation of the connexin43 promoter with Sp1

Keywords: LBD، دامنه اتصال لیگاند; Cx43, connexin43; AB, A/B region; DBD, DNA binding domain; H, hinge region; LBD, ligand binding domain; ER, Estrogen ReceptorConnexin43; Nuclear receptor; Rev-erbα; Rev-erbβ; Sp1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

PPARγ, an important gene related to lipid metabolism and immunity in Megalobrama amblycephala: Cloning, characterization and transcription analysis by GeNorm

Keywords: LBD، دامنه اتصال لیگاند; ACTB, beta-actin; DBD, DNA-binding domain; EF1a, elongation factor 1 alpha; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HPRT, hypoxanthine-guanine phosphoribosyltransferase; LBD, ligand binding domain; LH, luteinizing hormone; NAFLD, non-alcoholic fa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors

Keywords: LBD، دامنه اتصال لیگاند; FXR, farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; GPCR, G-protein coupled receptor; GLP-1, glucagon-like peptide 1; ChIP, chromatin immunoprecipitation; Cyp7a1, chol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Multiple structurally distinct ERα mRNA variants in zebrafish are differentially expressed by tissue type, stage of development and estrogen exposure

Keywords: LBD، دامنه اتصال لیگاند; AF, activation function; BPA, bisphenol A; DBD, DNA binding domain; DES, diethylstilbestrol; DMSO, dimethyl sulfoxide; E2, 17β-estradiol; EDC, endocrine disrupting chemicals; ER, estrogen receptor; hpf, hours post fertilization; LBD, ligand binding domain

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Allosteric Controls of Nuclear Receptor Function in the Regulation of Transcription

Keywords: LBD، دامنه اتصال لیگاند; DBD, DNA binding domain; LBD, ligand binding domain; RE, response element; RID, receptor interacting domain; GRE, GR binding sitenuclear receptors; allosteric regulation

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

CAC1 negatively regulates RARα activity through cooperation with HDAC

Keywords: LBD، دامنه اتصال لیگاند; CAC1, CDK2-associated cullin; RARα, retinoic acid receptor alpha; HDAC, histone deacetylase; AF-1, transcriptional activation function 1; LBD, ligand binding domain; DBD, DNA-binding domain; GST, glutathione S-transferase; β-gal, β-galactosidase; GFP, gre

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

8-Alkylthio-6-thio-substituted theophylline analogues as selective noncompetitive progesterone receptor antagonists

Keywords: LBD، دامنه اتصال لیگاند; AlkP, alkaline phosphatase; AR, androgen receptor; ER, estrogen receptor; GR, glucocorticoid receptor; LBD, ligand binding domain; PR, progesterone receptor; SAR, structure activity relationshipProgesterone; Steroid receptor; Small molecule inhibitor; The

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Daidzein has neuroprotective effects through ligand-binding-independent PPARγ activation

Keywords: LBD، دامنه اتصال لیگاند; CNS, central nervous system; CV, coefficient of variation; DIV, days in vitro; ERs, estrogens receptors; FITC, fluorescein isothiocyanate; LBD, ligand binding domain; LDH, lactate dehydrogenase; MCAO, middle cerebral artery occlusion; OGD, oxygen–glucose

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Development of docking-based 3D-QSAR models for PPARgamma full agonists

Keywords: LBD، دامنه اتصال لیگاند; LBD, ligand binding domain; PPAR, peroxisome proliferator-activated receptor; QSAR, quantitative structure–activity relationship; SAR, structure–activity relationship; TZDs, thiazolidinedionesPPARgamma agonists; 3D-QSAR; Antidiabetics; Drug design; Protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

QSAR model for human pregnane X receptor (PXR) binding: Screening of environmental chemicals and correlations with genotoxicity, endocrine disruption and teratogenicity

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; ER, estrogen receptor; EDC, endocrine disrupting chemical; EINECS, European Inventory of Existing Commercial Chemical Substances; HGPRT, hypoxanthine-guanine phosphoribosyl transferase; LBD, ligand binding domain; PLR, partial logis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Estrogen receptor dependent gene expression by osteoblasts – Direct, indirect, circumspect, and speculative effects

Keywords: LBD، دامنه اتصال لیگاند; ER, estrogen receptor; AF-1, activation function 1; DBD, DNA binding domain; ERE, estrogen response element; LBD, ligand binding domain; AF-2, activation function 2; GPCR, G protein coupled receptor; GPER, G protein coupled estrogen receptor; ERR, estroge

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Alternative sumoylation sites in the Drosophila nuclear receptor Usp

Keywords: LBD، دامنه اتصال لیگاند; EcR, ecdysone receptor; HEK293, human embryonic kidney 293 cells; HR38, hormone receptor 38; ID, intrinsically disordered; LBD, ligand binding domain; LBP, ligand binding pocket; Met, methoprene-tolerant; RXR, retinoid X receptor; SDS-PAGE, sodium dodecyl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Dynamics of coregulator-induced conformational perturbations in androgen receptor ligand binding domain

Keywords: LBD، دامنه اتصال لیگاند; AR, androgen receptor; DHT, 5-α-dihydrotestosterone; AF1, activation function 1; AF2, activation function 2; LBD, ligand binding domain; GST, glutathione S-transferase; FRET, fluorescent resonance energy transfer; TR-FRET, time resolved FRETAndrogen recep

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

Keywords: LBD، دامنه اتصال لیگاند; FXR, Farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptors; AF-1, activation function 1; AF-2, activation function 2; DBD, DNA binding domain; LBD, ligand binding domain; CDCA, chenodeoxycholic acid; FXRE, FXR response element;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Helix 12 Dynamics and Thyroid Hormone Receptor Activity: Experimental and Molecular Dynamics Studies of Ile280 Mutants

Keywords: LBD، دامنه اتصال لیگاند; nuclear hormone receptor; thyroid; cofactor recruitment; molecular dynamics simulationsNR, nuclear hormone receptor; H12, helix 12; LBD, ligand binding domain; TR, thyroid hormone receptor; RXR, retinoid X receptor; RAR, retinoic acid receptor; MD, molecu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Crystal structure of hereditary vitamin D-resistant rickets—Associated mutant H305Q of vitamin D nuclear receptor bound to its natural ligand

Keywords: LBD، دامنه اتصال لیگاند; NR, nuclear receptor; VDR, vitamin D NR; LBD, ligand binding domain; LBP, ligand binding pocketVDR mutant rickets; Calcitriol; Crystal structure

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus

Keywords: LBD، دامنه اتصال لیگاند; 20E, 20-hydroxyecdysone; EcR, ecdysone receptor protein; gDNA, genomic DNA; LBD, ligand binding domain; ORF, open reading frame; USP, ultraspiracle protein; RXR, retinoid X receptorEcdysteroid; Ecdysone receptor; EcR; Haemonchus contortus; 20-Hydroxyecdys

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Unliganded estrogen receptor-β regulation of genes is inhibited by tamoxifen

Keywords: LBD، دامنه اتصال لیگاند; ER, estrogen receptor; AF, activation function; LBD, ligand binding domain; SRC, steroid receptor coactivator; ChIP, chromatin immunoprecipitation; PCR, polymerase chain reaction; shRNA, short hairpin RNAEstrogen receptor; Selective estrogen receptor modu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Identification and characterization of a novel estrogenic ligand actinopolymorphol A

Keywords: LBD، دامنه اتصال لیگاند; BRET, bioluminescence resonance energy transfer; ERα, estrogen receptor α; ERβ, estrogen receptor β; LBD, ligand binding domain; FP, Fluorescence Polarization; HTS, high throughput screening; NPE, natural product extract; EDC, endocrine disrupting compoun

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

Keywords: LBD، دامنه اتصال لیگاند; GR, glucocorticoid receptor; PR, progesterone receptor; NR, nuclear hormone receptor; LBD, ligand binding domain; NCoR, nuclear receptor corepressor; PDB, Protein Data Bank; GST, glutathione S-transferase; TCEP, tris(2-carbohyethyl)phosphinenuclear recept

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Nuclear receptor coregulators as a new paradigm for therapeutic targeting

Keywords: LBD، دامنه اتصال لیگاند; NR, nuclear hormone receptor; LBD, ligand binding domain; DBD, DNA binding domain; SERM, selective estrogen receptor modulator; SRC, steroid receptor coactivator; ACTR, activator for receptors; AIB1, amplified in breast cancer 1; TIF2, transcriptional int

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Rational quantitative structure–activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands

Keywords: LBD، دامنه اتصال لیگاند; BPA, bisphenol A; CAR, constitutive androstane receptor; CITCO, 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime; DMSO, dimethylsulfoxide; LBD, ligand binding domain; NR, nuclear receptor; PK11195, 1-(2-chlorophenyl

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains

Keywords: LBD، دامنه اتصال لیگاند; kainate receptor; glycosylation; structural biology; cell surface receptor; synaptic plasticityiGluR, ionotropic glutamate receptor; NMDA, N-methyl-d-aspartic acid; ATD, amino-terminal domain; LBD, ligand binding domain; Endo H, endoglycosidase H; ESI, el

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Insight into estrogenicity of phytoestrogens using in silico simulation

Keywords: LBD، دامنه اتصال لیگاند; Estrogen receptor; Phytoestrogen; Miroestrol; in silico simulation; Docking; Molecular dynamics; Linear interaction energyER, estrogen receptor; LBD, ligand binding domain; MD, molecular dynamics; LIE, linear interaction energy; RMSD, root-mean-square dev

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Structural Insight into PPARγ Activation Through Covalent Modification with Endogenous Fatty Acids

Keywords: LBD، دامنه اتصال لیگاند; PPAR,,  peroxisome proliferator-activated receptor; LBD, ligand binding domain; 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; oxoETE, oxidized eicosatetraenoic acidPPARγ; nuclear receptor; endogenous fatty acids; covalent modification; partial agnosim

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Highly twisted adamantyl arotinoids: Synthesis, antiproliferative effects and RXR transactivation profiles

Keywords: LBD، دامنه اتصال لیگاند; Adamantyl arotinoids; Retinoid-related molecules (RRMs); RXR; Apoptosis; Synthesis9cRA, 9-cis-retinoic acid; AdAr, adamantyl arotinoid; atRA, all-trans-retinoic acid; IKK, IκB kinase; JNK, cJun N-terminal kinase; LBD, ligand binding domain; MAPK, mitogen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Orthologues of the Drosophila melanogaster E75 molting control gene in the filarial parasites Brugia malayi and Dirofilaria immitis

Keywords: LBD، دامنه اتصال لیگاند; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; RT-PCR, reverse transcription-polymerase chain reaction; PCR, polymerase chain reaction; CTE, carboxy terminal extension; EMSA, electrophoretic mobility shift assay; AF-2 AD, activ

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

The variety of complexes formed by EcR and Usp nuclear receptors in the nuclei of living cells

Keywords: LBD، دامنه اتصال لیگاند; 20E, 20-hydroxyecdysone; BiFC, bimolecular fluorescence complementation; CFP, cyan fluorescence protein; EcR, product of EcR gene; FRAP, fluorescence recovery after photobleaching; LBD, ligand binding domain; NES, nuclear export signal; NLS, nuclear local

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of intranuclear binding process of glucocorticoid receptor using fluorescence correlation spectroscopy

Keywords: LBD، دامنه اتصال لیگاند; FCS, fluorescence correlation spectroscopy; FAF, fluorescence autocorrelation function; EGFP, enhanced green fluorescent protein; Dex, dexamethasone; LBD, ligand binding domain; DBD, DNA binding domain; GR, glucocorticoid receptor; GRE, glucocorticoid res

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Diffusion analysis of glucocorticoid receptor and antagonist effect in living cell nucleus

Keywords: LBD، دامنه اتصال لیگاند; FCS, fluorescence correlation spectroscopy; FAF, fluorescence autocorrelation function; EGFP, enhanced green fluorescent protein; Dex, dexamethasone; LBD, ligand binding domain; DBD, DNA binding domain; GR, glucocorticoid receptor; GRE, glucocorticoid res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II

Keywords: LBD، دامنه اتصال لیگاند; ArPII, aromatase promote II; DMSO, dimethyl sulfoxide; LBD, ligand binding domain; LRH-1, liver receptor homolog-1; PKA, protein kinase A; QCM, quartz crystal microbalance; SF-1, steroidogenic factor 1; SPR, surface plasmon resonanceAromatase; Steroidogen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Characterization of transcriptional regulatory domains of ankyrin repeat cofactor-1

Keywords: LBD، دامنه اتصال لیگاند; ANCO-1, ankyrin repeats cofactor-1; RAC3, nuclear receptor-associated cofactor-3; PR, progesterone receptor; HDAC, histone deacetylases; DBD, DNA binding domain; LBD, ligand binding domain; RD, repression domain; AD, activation domainANCO-1; Ankyrin repea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of ligand-dependent recruitment of coactivator peptides to RXRβ in a time-resolved fluorescence resonance energy transfer assay

Keywords: LBD، دامنه اتصال لیگاند; RXR, retinoid X receptor; TR, thyroid hormone receptor; PPAR, peroxisome proliferator-activated receptor; RAR, retinoic acid receptor; LXR, liver X receptor; LBD, ligand binding domain; TR-FRET, time-resolved fluorescence resonance energy transfer; 9-cisR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Allosteric modulation of nicotinic acetylcholine receptors

Keywords: LBD، دامنه اتصال لیگاند; ACh, acetylcholine; nAChRs, neuronal nicotinic acetylcholine receptors; DMPP, dimethylphenylpiperazinium; 5-HI, 5-hydroxyindole; PAM, positive allosteric modulator; NAM, negative allosteric modulator; BSA, bovine serum albumine; LBD, ligand binding domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities

Keywords: LBD، دامنه اتصال لیگاند; Arylidene-thiazolidinediones; Hypoglycemic; Hypolipidemic; Molecular modeling; DockingADT, auto docking tools; ATZDs, arylidene-thiazolidinediones; DM, diabetes mellitus; LBD, ligand binding domain; PG, plasmatic glucose level; PPAR, peroxisome proliferat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular cloning and expression analysis of ecdysone receptor and retinoid X receptor from the kuruma prawn, Marsupenaeus japonicus

Keywords: LBD، دامنه اتصال لیگاند; EcR, ecdysone receptor; RXR, retinoid X receptor; DBD, DNA binding domain; LBD, ligand binding domain; qPCR, quantitative real-time PCREcdysone receptor; Marsupenaeus japonicus; Molting mechanism; Retinoid X Receptor

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Oestrogen receptors pathways to oestrogen responsive elements: The transactivation function-1 acts as the keystone of oestrogen receptor (ER)β-mediated transcriptional repression of ERα

Keywords: LBD، دامنه اتصال لیگاند; ER, oestrogen receptor; AF, activation function; DBD, DNA binding domain; LBD, ligand binding domain; NcoR, nuclear receptor co-repressor; SMRT, silencing mediator for retinoid-and thyroid-hormone receptors; ERE, oestrogen response element; Vit, 3xERE-vit

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Non-genomic ecdysone effects and the invertebrate nuclear steroid hormone receptor EcR—new role for an “old” receptor?

Keywords: LBD، دامنه اتصال لیگاند; Ec, ecdysteroid(s); E, ecdysone; 20E, 20-hydroxyecdysone; PoA, ponasterone A; D3, 1α,25(OH)2-Vitamin D3; NR, nuclear hormone receptor; EcR, ecdysteroid receptor; VDR, Vitamin D receptor; ER, estrogen receptor; LBD, ligand binding domain; PCN, protocerebra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه