Keywords: لئوتریژن A4 هیدرولاز; RPKM; reads per kilobase of transcript per million mapped reads; FGF; fibroblast growth factor; ETS; E26 transformation-specific or E-twenty-six; LTs; leukotrienes; ALOX5; arachidonate 5-lipoxygenase; LTA4; leukotriene A4; LTB4; leukotriene B4; LTC4; leuk
مقالات ISI لئوتریژن A4 هیدرولاز (ترجمه نشده)
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Keywords: لئوتریژن A4 هیدرولاز; CD13; Bestatin; Diabetic retinopathy; Leukotriene A4 hydrolase; Retina permeability; ECM;
Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis
Keywords: لئوتریژن A4 هیدرولاز; atherosclerosis; burden; imaging; inflammation; permeability; 18F-FDG; 18F-fluorodeoxyglucose; 3D; 3-dimensional; 5LO; 5-lypoxigenase; AUC; area under the curve; CT; computed tomography; DCE; dynamic contrast-enhanced; FLAP; 5-LO-activating protein; HFD;
Effect of alpha lipoic acid on leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4; Leukotrienes synthesis; Leukotriene A4 hydrolase; Alpha lipoic acid; Proline-glycine-proline;
Synthesis and biological evaluation of novel 1,2,3-benzotriazin-4-one derivatives as leukotriene A4 hydrolase aminopeptidase inhibitors
Keywords: لئوتریژن A4 هیدرولاز; 1,2,3-Benzotriazin-4-one; Leukotriene A4 hydrolase; Aminopeptidase activity; In vitro; Aminopeptidase inhibitors;
Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation
Keywords: لئوتریژن A4 هیدرولاز; 4-MDM; 4-methoxydiphenylmethane; ACN; acetonitrile; APPI; atmospheric pressure photoionization; BCS; biopharmaceutical classification system; CAD; collision activated dissociation; CE; collision energy; COPD; chronic obstructive pulmonary disease; CEP; co
Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors
Keywords: لئوتریژن A4 هیدرولاز; 5-LOX; 5-Lipoxygenase; AA; Arachidonic acid; FLAP; 5-Lipoxygenase-activating protein; GSH; Glutathione; LT; Leukotriene; LTA4H; Leukotriene A4 hydrolase; cys-LTs; Cysteinyl leukotrienes; MAPEG; Membrane-associated protein in eicosanoid and glutathione met
Thermodynamic properties of leukotriene A4 hydrolase inhibitors
Keywords: لئوتریژن A4 هیدرولاز; LTA4H; leukotriene A4 hydrolase; LTA4; leukotriene A4; LTB4; leukotriene B4; kDa; kilo Dalton; PGP; prolin-glycin-prolin; TSA; thermal shift assay; TM; melting point; ITC; isothermal titration calorimetry; DSF; different scanning fluorimetry; Ki; inhi
A multispecies Lactobacillus- and Bifidobacterium-containing probiotic mixture attenuates body weight gain and insulin resistance after a short-term challenge with a high-fat diet in C57/BL6J mice
Keywords: لئوتریژن A4 هیدرولاز; CLAs; conjugated linoleic acids; CT; control diet; FIAF; fasting-induced adipocyte factor; GLP-1; glucagon-like peptide-1; HF; high-fat diet; HF-Pb; high-fat diet with probiotic mixture; 5-HPETE; 5-hydroperoxyeicosatetraenoic acid; IBS; inflammatory bowel
The M1 family of vertebrate aminopeptidases: Role of evolutionarily conserved tyrosines in the enzymatic mechanism of aminopeptidase B
Keywords: لئوتریژن A4 هیدرولاز; Aminopeptidases; Zn2+-metallopeptidase; Leukotriene A4 hydrolase; M1 family; TyrosineAp-A, aminopeptidase A; Ap-B, aminopeptidase B; Ap-N, aminopeptidase N; Ap-O, aminopeptidase O; Ap-Q, aminopeptidase Q; RNPEP-L1, arginyl aminopeptidase-like 1; CCK, chol
Relationship between human LTA4H polymorphisms and extra-pulmonary tuberculosis in an ethnic Han Chinese population in Eastern China
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4 hydrolase; Single nucleotide polymorphism; Extra-pulmonary tuberculosis; Pulmonary tuberculosis;
Product formation controlled by substrate dynamics in leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4 hydrolase; X-ray crystallography; Xenopus laevis; Small angle X-ray scattering;
Role of glutamine-169 in the substrate recognition of human aminopeptidase B
Keywords: لئوتریژن A4 هیدرولاز; APB; aminopeptidase B; IC50; half maximal (50%) inhibitory concentration; EC50; half maximal (50%) effective concentration; ERAP; endoplasmic reticulum aminopeptidase; LTA4H; leukotriene A4 hydrolase; MCA; 4-methylcoumaryl-7-amide; NRD; N-arginine dibasic
Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; Leukotrienes; LTA4H; Leukotriene A4 hydrolase; Leukotriene B4 hydrolase
Engagement of the S1, S1â² and S2â² subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum
Keywords: لئوتریژن A4 هیدرولاز; AccQ·Tag; 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate; IMAC; immobilized metal affinity chromatography; LTA4H; leukotriene A4 hydrolase; PfA-M1; P. falciparum aminopeptidase-M1 family; Malaria; Peptidase; Vacuole; Hemoglobin; Enzyme kinetics;
Azabenzthiazole inhibitors of leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; hERG; Log D; LTA4H; Leukotriene A4 hydrolase; Antiinflammatory;
The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway
Keywords: لئوتریژن A4 هیدرولاز; HLJDT; Huang-Lian-Jie-Du-Tang; AA; arachidonic acid; LTB4; leukotriene B4; 5-HETE; 5-hydroxyeicosatetraenoic acid; 12-HHT; 12-hydroxy-5,8,10-heptadecatrienoic acid; LTA4H; leukotriene A4 hydrolase; LO; lipoxygenase; COX; cyclo-oxygenase; OTC; over-the-cou
Pharmacophore-based virtual screening and Bayesian model for the identification of potential human leukotriene A4 hydrolase inhibitors
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4 hydrolase; Inflammation; Pharmacophore; Database searching; Molecular docking; Bayesian modelLTA4H, leukotriene A4 hydrolase; hLTA4H, human leukotriene A4 hydrolase; AA, arachidonic acid; LT, leukotrienes; cPLA2, cytosolic phospholipase A2;
Mutation in the substrate-binding site of aminopeptidase B confers new enzymatic properties
Keywords: لئوتریژن A4 هیدرولاز; Zn2+-metallopeptidase; Miniglucagon; Hormone processing; Neuropeptide processing; Leukotriene A4 hydrolase; M1 familyACE, angiotensine converting enzyme; Ap-A, glutamyl aminopeptidase; Ap-B, aminopeptidase B; Ap-N, aminopeptidase N; Ap-O, aminopeptidase O
A Leukotriene A4 Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit upon Inhibitor Binding
Keywords: لئوتریژن A4 هیدرولاز; leukotriene A4 hydrolase; aminopeptidase; epoxide hydrolase; catalysis; crystallographyscLTA4H, leukotriene A4 hydrolase from Saccharomyces cerevisiae; GST, gluthathione S-transferase; PEG, polyethylene glycol; Tris, tris(hydroxymethyl)aminomethane; ES, 2
Structures and mechanisms of enzymes in the leukotriene cascade
Keywords: لئوتریژن A4 هیدرولاز; Leukotrienes; Leukotriene A4 hydrolase; Leukotriene C4 synthase; 5-Lipoxygenase; Phospholipase A2; Arachidonic acid
Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration
Keywords: لئوتریژن A4 هیدرولاز; Antigen-presenting cells; eicosanoids; exosomes; inflammation; leukotrienes; TGF-β1; AA; Arachidonic acid; APC; Antigen-presenting cell; cysLT; Cysteinyl leukotriene; DC; Dendritic cell; FITC; Fluorescein isothiocyanate; FLAP; 5-Lipoxygenase-activating
Importance of non-conserved distal carboxyl terminal amino acids in two peptidases belonging to the M1 family: Thermoplasma acidophilum Tricorn interacting factor F2 and Escherichia coli Peptidase N
Keywords: لئوتریژن A4 هیدرولاز; C-Terminal domain; Cytosolic protein degradation; Enzyme solubility and function; Metallopeptidase; M1 family; aa; amino acids; AAP1; alanine/arginine aminopeptidase; AMC; 7-amino-4-methylcoumarin; ANS; 8-anilino 1-napthalene sulphonic acid; ARM; Armadill
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4; LTA4; Leukotriene A4 hydrolase; Enzyme inhibitor; Antiinflammatory
Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; Leukotriene A4; Leukotriene A4 hydrolase; Anti-inflammatory; Enzyme inhibitor
Cold adaptation of enzymes: Structural, kinetic and microcalorimetric characterizations of an aminopeptidase from the Arctic psychrophile Colwellia psychrerythraea and of human leukotriene A4 hydrolase
Keywords: لئوتریژن A4 هیدرولاز; ColAP, Colwellia psychrerythraea aminopeptidase; LTA4H, human leukotriene A4 hydrolase; DSC, differential scanning calorimetryPsychrophile; Cold-active enzyme; Aminopeptidase; Colwellia psychrerythraea; Leukotriene A4 hydrolase