Keywords: 5,10-CH2-THF; 5,10-methylene-tetrahydrofolate; CHX; cycloheximide; C; HCC tissues; DAPI; 4,6â²-diamidino-2-phenylindole; DCFH-DA; 2â²,7â²-Dichlorofluorescin diacetate; DMEM; Dulbecco's modified Eagle medium; ECL; enhanced chemiluminescence; EGF; epider
مقالات ISI (ترجمه نشده)
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Keywords: ALS; Amyotrophic lateral sclerosis; DMD; DuchenneMuscular Dystrophy; SMA; Spinalmuscular atrophy; FAP; FamilialAmyloid Polyneuropathy; OD; Orphandisease; ORD; Officeof Rare Diseases; NIH; NationalInstitutes of Health; sALS; SporadicALS; fALS; FamilialALS;
Keywords: Di-n-butyl phthalate (DBP); Neuroplasticity; Rho-GTPase; ANOVA; analysis of variance; BBP; benzyl butyl phthalate; CREB; cyclic adenosine monophosphate response element binding protein; DBP; di-n-butyl phthalate; DiBP; diisobutyl phthalate; DEHP; di(2-eth
Keywords: Conditioning; Nucleus accumbens; AMPA; Arp2/3; Cofilin; Actin; AMPAR; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor; Arp2/3; actin-related protein 2/3; CS; conditioned stimulus; DA; dopamine; IP; intraperitoneal; LIMK; LIM-domain-containing
Keywords: CAPRI; Ca2+-promoted RAS inactivator; CRMP-2; collapsin response mediator protein-2; CSRD; cysteine/serine-rich domain; CTD; C-terminal domain; ERK; extracellular signal-regulated kinase; FTI; farnesyltransferase inhibitor; FAK1; focal adhesion kinase 1;
Keywords: AIP1; actin-interacting protein-1; APRT; adenine phosphoribosyltransferase; BAT; brown adipose tissue; CAP; cyclase-associated protein; CFL-1; cofilin-1; COL1A1; collagen alpha-1(i) chain; ECHS1; enoyl-CoA hydratase; EEF-2; elongation factor 2; EndoB1; en
Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis
Keywords: YD0514; Aziridonin; Breast cancer; Metastasis; NRF-2/RHOA/ROCK pathway; Oridonin; BSA; bovine serum albumin; CFL; cofilin; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EMT; epithelial-mesenchymal transition; ER; estrogen receptor; F
Paving the Rho in cancer metastasis: Rho GTPases and beyond
Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena
Dual effect of serotonin on the dendritic growth of cultured hippocampal neurons: Involvement of 5-HT1A and 5-HT7 receptors
Keywords: Serotonin; 5-HT1AR; 5-HT7R; Outgrowth; Dendrite; Hippocampal neurons; ERK1/2; AKT; GSK3β; LIMK; Cofilin;
The Rho-specific guanine nucleotide exchange factor Plekhg5 modulates cell polarity, adhesion, migration, and podosome organization in macrophages and osteoclasts
Keywords: Rho-GEF; Rho-specific guanine-nucleotide exchange factor; EB; end-binding protein; LIMK; LIM kinase; RANKL; Receptor activator of nuclear factor kappa-B ligand; DAPI; 4â², 6-diamidino-2-phenylindole, dihydrochloride; M-CSF; macrophage colony- stimulating
Functions of Rho family of small GTPases and Rho-associated coiled-coil kinases in bone cells during differentiation and mineralization
Keywords: AGC; protein kinase A, G, and C families (PKA, PKC, PKG) of cytoplasmic serine/threonine kinases; AnxA; vertebrate annexin; ALP; alkaline phosphatase; ANK; progressive ankylosis protein; BMP; bone morphogenetic protein; BSP; bone sialoprotein; CHOL; chole
Design, synthesis and biological characterization of selective LIMK inhibitors
Keywords: Kinase inhibitor; LIMK; ROCK; SAR; LX-7101
Rho is involved in periodontal tissue remodelling with experimental tooth movement in rats
Keywords: Rho signalling pathway; ROCK; LIMK; Cofilin; Tooth movement; Periodontal tissue remodelling;
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Keywords: 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4â²,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green
Discovery of a new HIV-1 inhibitor scaffold and synthesis of potential prodrugs of indazoles
Keywords: CDKs; cyclin-dependent kinases; CKII; casein kinase 2; DMAP; dimethylaminopyridine; EDCI; N-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; LIMK; LIM kinases; PK; pharmacokinetics; TFA; trifluoroacetic acid; HIV; Drug target; Oxazoles; Prodrugs
Identification of DAPK as a scaffold protein for the LIMK/cofilin complex in TNF-induced apoptosis
Keywords: TNF; DAPK; LIMK; Cofilin; Apoptosis;
LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4
Keywords: F-actin; filamentous actin; G-actin; globular actin; LIMK; LIM domain kinase; LRRK2; leucine-rich repeat kinase 2; PAK; p21 protein (Cdc42/Rac)-activated kinase; qRT-PCR; quantitative reverse transcription polymerase chain reaction; GEF; guanine nucleotid
Dendritic spine plasticity as an underlying mechanism of neuropathic pain: Commentary on Tan et al.
Keywords: AMPA; 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; aPKC; atypical protein kinase C; BDNF; brain derived neurotrophic factor; CCI; chronic constriction injury; DHPG; dihydroxyphenyglycine; FMRP; fragile X mental retardation protein; IL-6; inte
Vitreous-induced cytoskeletal rearrangements via the Rac1 GTPase-dependent signaling pathway in human retinal pigment epithelial cells
Keywords: PVR; proliferative vitreoretinopathy; RPE; retinal pigment epithelial cells; ERM; epiretinal membrane; EMT; epithelial-mesenchymal transdifferentiation; LIMK; LIM kinase; Cytoskeletal rearrangement; Rac1 GTPase; Vitreous; Human retinal pigment epithelia
Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling
Keywords: EMT; Cadherin-6B; BMP; Non-canonical; LIMK; Cofilin; Neural crest;
Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2
Keywords: OPG; osteoprotegerin; M-CSF; macrophage-colony stimulating factor; MEK; mitogen activated protein kinase kinase; ERK; extracellular signal regulated kinase; MAPK; mitogen activated protein kinase; FPP; farnesyl pyrophosphate; GGPP; geranylgeranyl pyrophos
Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis
Keywords: Limk; Kidney; Heart; Epithelia-to-mesenchyme transition; Mesenchyme-to-epithelia transition; Eye; Testes
Differing contributions of LIMK and ROCK to TGFβ-induced transcription, motility and invasion
Keywords: TGFβ; Rho; LIMK; ROCK; Actin cytoskeleton; EMT; Kinase
Tropomyosin isoform 3 promotes the formation of filopodia by regulating the recruitment of actin-binding proteins to actin filaments
Keywords: ABP(s); actin-binding protein(s); ADF; actin depolymerizing factor; Arp; actin-related protein; HMW; high molecular weight; LimK; Lim kinase; LMW; low molecular weight; PBS; phosphate-buffered saline; s.d.; standard deviation; Tm(s); tropomyosin(s); Actin
A PAK4–LIMK1 pathway drives prostate cancer cell migration downstream of HGF
Keywords: PAK4; LIMK; Cofilin; Prostate; Cancer; Motility; FRET
Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition
Keywords: LIMK; Actin; Cofilin; Mitosis; Mitotic spindle; Microtubule; Cytokinesis; Phosphorylation
Lim kinase regulates the development of olfactory and neuromuscular synapses
Keywords: Olfactory; Antennal Lobe; Glomeruli; Synapse; Pak; Limk; Cofilin
Hepatocyte growth factor, its receptor, and their potential value in cancer therapies
Keywords: Abl; Abelson murine leukemia viral oncogene; AGTR; angiotensin II receptor; Arf; Archaeal Rieske-type ferredoxin; Arp; actin-related protein; BCL2; B-cell CLL/lymphoma 2; BID; BH3 interacting domain death agonist; cMET; receptor for hepatocyte growth fact