Keywords: بازده لیپوفیلی; Lipophilic efficiency; Ligand efficiency; Composite parameters; Efficiency metrics;
مقالات ISI بازده لیپوفیلی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors
Keywords: بازده لیپوفیلی; 7-Azaindole; Solubilizing group; Structure-based design; Lipophilic efficiency; Rho kinase; ROCK;
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes
Keywords: بازده لیپوفیلی; ADME; absorption, distribution, metabolism and excretion; Clint; intrinsic clearance; Clp; plasma clearance; Clu; unbound clearance; DCM; dichloromethane; DHEP; dog hepatocytes; DLM; dog liver microsomes; DMAc; dimethylacetamide; DMF; dimethylformamide; D
Diverse amide analogs of sulindac for cancer treatment and prevention
Keywords: بازده لیپوفیلی; NSAID; non-steroidal anti-inflammatory drug; COX; cyclooxygenase; SSA; sulindac sulfide amide; SAR; structure-activity relationship; AA; amino acid; ALL; acute lymphoblastic leukemia; CPC; choroid plexus carcinoma; TPSA; topological polar surface area; Li
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development
Keywords: بازده لیپوفیلی; Translocator protein; PET; Carbon-11; Ligand; Binding affinity; Lipophilic efficiency; DIPEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; HFIP; hexafluoroisopropyl alcohol; HRMS-ESI; high resolution mass spectrometry electr
The thermodynamic basis for the use of lipophilic efficiency (LipE) in enthalpic optimizations
Keywords: بازده لیپوفیلی; Lipophilic efficiency; Ligand efficiency; Enthalpy; Composite parameters; Thermodynamics;
Nitroimidazolyl hydrazones are better amoebicides than their cyclized 1,3,4-oxadiazoline analogues: In vitro studies and Lipophilic efficiency analysis
Keywords: بازده لیپوفیلی; Acylhydrazone; Oxadiazoline; Lipophilic efficiency; Entamoeba histolytica; HepG2;
Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC
Keywords: بازده لیپوفیلی; LpxC; Antibacterial; Gram negative; Structure based drug design; Hydroxamic acid; Pseudomonas aeruginosa; LipE; Lipophilic efficiency; Computer aided drug design
Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region
Keywords: بازده لیپوفیلی; PDE5 inhibitors; Pyrazinones; Lead optimization; Ligand efficiency; Lipophilic efficiency
Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies
Keywords: بازده لیپوفیلی; Binding efficiency index; Ligand efficiency; Cannabinoid CB2 receptor; Inverse agonist; Polar surface area; Lipophilicity; Subtype selectivity; Ligand-lipophilicity efficiency; Lipophilic efficiency
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275
Keywords: بازده لیپوفیلی; 11-β-Hydroxysteroid dehydrogenase; PF-915275; Diabetes; Lipophilic efficiency