Keywords: Complexation and protection of plasmid DNA; Gemini cationic lipid with aromatic spacer; Lipoplexes; Structure and morphology; Gene delivery;
مقالات ISI (ترجمه نشده)
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Keywords: Lipoplexes; Leukocyte uptake; Gene delivery; PEGylation;
Keywords: Hyaluronic acid; Lipoplexes; Retinal gene therapy; Intravitreal administration; Nanoparticle mobility;
Keywords: Microfluidics; Gene delivery; DNA; Liposomes; Lipoplexes; Nanocarriers;
Keywords: a.u.; arbitrary units; CC; point of charge compensation; Chol; cholesterol; CLSM; confocal laser scanning microscopy; CV; cell viability; DLS; dynamic light scattering; DOPC; 1,2-di-[(9Z)-octadec-9-enoyl]-sn-glycero-3-phosphocholine; DOPE; 1,2-dioleoyl-sn
Keywords: Lipoplexes; Gene therapy; Non-viral carriers; Kinetics; DNA/lipid; siRNA; Cryo-TEM
Keywords: Gene delivery; Cationic liposome; Lipoplexes; Reducible tocopherol-based cationic amphiphiles; Lipofection; DNA release; Lipofect; LipofectAmine-2000; DMEM; Dulbecco's modified Eagle's medium; DMAP; 4-(dimethylamino)pyridine; FBS; fetal bovine serum; PBS;
Cationic lipid/DNA complexes manufactured by microfluidics and bulk self-assembly exhibit different transfection behavior
Keywords: Cationic liposomes; Lipoplexes; Self-assembling; Microfluidic mixing; Transfection efficiency; Cytotoxicity;
Collapse of DNA in packaging and cellular transport
Keywords: DNA condensation; Polyamines; DNA nanoparticles; Polyethyleneimine; Dendrimers; Lipoplexes; Gene therapy; Polyelectrolyte theory;
Design and synthesis of biologically active cationic amphiphiles built on the calix[4]arene scaffold
Keywords: Calix[4]arenes; Aminoglycosides; Non-viral gene delivery vectors; Antibacterial activity; Transfection; Lipoplexes;
cmRNA/lipoplex encapsulation in PLGA microspheres enables transfection via calcium phosphate cement (CPC)/PLGA composites
Keywords: PLGA; Transcript therapy; Microparticles; Calcium phosphate cements; Lipoplexes; Bone substitute materials;
Research paper'Nano-in-nano' hybrid liposomes increase target specificity and gene silencing efficiency in breast cancer induced SCID mice
Keywords: Liposome; siRNA; Gene delivery; Lipoplexes; RNAi; Poly-l-lysine; EpCAM; Hybrid liposomes;
Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus
Keywords: Infections; Lipoplexes; Gastric mucus; Nucleic acid mimics; Helicobacter pylori;
Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells
Keywords: Cell transfection; Transfection efficiency; Hard-to-transfect cells; Cationic liposomes; Lipoplexes;
Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model
Keywords: Lipoplexes; siRNA; Hyaluronic acid; A549; CD44; Luciferase;
Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes: Towards a vaginal sustained released system for siRNA
Keywords: Ceramide-PEG2000; N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}; DSPE-PEG2000; 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]; DSPE-PEG750; 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[m
Cyclen-based double-tailed lipids for DNA delivery: Synthesis and the effect of linking group structures
Keywords: Boc; tert-butoxycarbonyl; cyclen; 1, 4, 7, 10-tetraazacyclododecane; lipoplexes; liposome/DNA complexes; TE; gene transfection efficiency; EDC HCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt; 1-hydroxybenzotriazole; TFA; trifluoroac
Delivery of oligonucleotides with lipid nanoparticles
Keywords: Lipid nanoparticles; Liposome; Lipoplexes; Oligonucleotides; Systemic delivery;
Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes
Keywords: siRNA; Liposomes; Cationic lipids; Lipoplexes; siRNA delivery; siRNA selection; Clinical trials; Endosomal escape;
Application of Polyglycerol Coating to Plasmid DNA Lipoplex for the Evasion of the Accelerated Blood Clearance Phenomenon in Nucleic Acid Delivery
Keywords: accelerated blood clearance (ABC) phenomenon; anti-PEG IgM; clearance; lipoplexes; non-viral gene delivery; PEGylation; plasmid DNA (pDNA); polyethylene glycol (PEG); polyglycerol (PG);
Shock Waves and DNA-Cationic Lipid Assemblies: A Synergistic Approach to Express Exogenous Genes in Human Cells
Keywords: Cell transfection; Shock waves; Lipoplexes; Acoustic cavitation; HEK 293 cells;
Structural dynamics and physicochemical properties of pDNA/DODAB:MO lipoplexes: Effect of pH and anionic lipids in inverted non-lamellar phases versus lamellar phases
Keywords: Lipoplexes; Nile Red; FRET; Light scattering; Cryo-TEM; Transfection;
DNA delivery via cationic solid lipid nanoparticles (SLNs)
Keywords: Non-viral vectors; Lipoplexes; Gene therapy; Solid lipid nanoparticles; Cationic nanoparticles; Drug delivery systems;
Oligonucleotides and polynucleotides condensation onto liposome surface: Effects of the base and of the nucleotide length
Keywords: DOTAP, 1,2-dioleoyl-3-trimethylammonium-propane; DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DNA, deoxyribonucleic acid; DLS, dynamic light scatteringLiposome; ζ-Potential; Hydrophobic interaction; Nucleic acids; Lipoplexes
Cationic lipid:DNA complexes allow bleomycin uptake by melanoma cells
Keywords: Canine melanoma; Lipoplexes; Spheroids; Chemotherapy; Bleomycin;
AFM and TEM characterization of siRNAs lipoplexes: A combinatory tools to predict the efficacy of complexation
Keywords: Phase Atomic Force Microscopy; Transmission electron microscopy; Lipoplexes; siRNA; Postpegylation technique
Reduced in vitro and in vivo toxicity of siRNA-lipoplexes with addition of polyglutamate
Keywords: RNA interference; Cationic lipid; Anionic polymers; Gene silencing; siRNA; Lipoplexes
Impact of Plasmid Quality on Lipoplex-Mediated Transfection
Keywords: gene delivery; gene therapy; lipoplexes; downstream processing; plasmid DNA; purification; transfection;
Lectin functionalized nanocarriers for gene delivery
Keywords: Nanocarriers; Lectin; DNA; siRNA; Transfection; Lipoplexes; Polyplexes; Dendriplexes; Gene delivery
Liposomal surface coatings of metal stents for efficient non-viral gene delivery to the injured vasculature
Keywords: Stent; Non-viral gene therapy; Vasculature; Lipid; Lipoplexes;
siRNA LNCs – A novel platform of lipid nanocapsules for systemic siRNA administration
Keywords: Nanocarrier; Lipoplexes; Formulation; siRNA quantification; Cationic lipids; Systemic administration
Specific interactions between nucleolipid doped liposomes and DNA allow a more efficient polynucleotide condensation
Keywords: Lipoplexes; Nucleolipids; Molecular interaction; Nucleic acids; Self-assembly; Zeta potentialDP-Cyt, 1,2-Dipalmitoyl-sn-glycero-3-cytidine diphosphate; DOTAP, 1,2-Dioleoyl-3-trimethylammonium-propane; DOPE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; D
Hyaluronic acid-bearing lipoplexes: Physico-chemical characterization and in vitro targeting of the CD44 receptor
Keywords: Lipoplexes; Hyaluronic acid; A549; CD44; Endocytosis; Complement activation;
Chemical oxidation of a redox-active, ferrocene-containing cationic lipid: Influence on interactions with DNA and characterization in the context of cell transfection
Keywords: Cationic lipids; Lipoplexes; DNA delivery; Nanostructure; Ferrocene;
Factors affecting DNA binding and stability of association to cationic liposomes
Keywords: DOTAP; N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethyl-ammonium chloride; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine; PC; phosphatidylcholine; DCP; dicetylphosphate; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine; SDS; sodium dodecyl sulf
Addition of ascorbic acid to the extracellular environment activates lipoplexes of a ferrocenyl lipid and promotes cell transfection
Keywords: Ferrocenyl lipid; Lipoplexes; Transfection; Nanostructure; Ascorbic acid; External stimulus;
Complexes of nucleolipid liposomes with single-stranded and double-stranded nucleic acids
Keywords: Self-assembly; Nucleolipids; DNA delivery; Lipoplexes;
Polyadenylic acid binding on cationic liposomes doped with the non-ionic nucleolipid Lauroyl Uridine
Keywords: Liposomes; Lipoplexes; Nucleolipid; Lauroyl Uridine; Molecular interaction; Polynucleotides
Existence of hybrid structures in cationic liposome/DNA complexes revealed by their interaction with plasma proteins
Keywords: Cationic liposomes; DNA; Lipoplexes; Plasma proteins; Protein corona
Assembly and characterization of lipid–lipid binding protein particles
Keywords: Liposomes; Lipid binding Proteins; Lipoplexes; Vaccines; Particle characterization
Anionic polymers for decreased toxicity and enhanced in vivo delivery of siRNA complexed with cationic liposomes
Keywords: RNA interference; Cationic lipid; Anionic polymers; Gene silencing; siRNA; Lipoplexes
CLINICAL TRIALS AND TRANSLATIONAL MEDICINE COMMENTARY: Drug Delivery Trends in Clinical Trials and Translational Medicine: Challenges and Opportunities in the Delivery of Nucleic Acid-Based Therapeutics
Keywords: biotechnology; cationic lipids; DNA/oligonucleotide delivery; encapsulation; gene delivery; gene vectors; lipoplexes; macromolecular drug delivery; nanoparticles; nonviral gene delivery
DNA induced dimerization of a sulfhydryl surfactant in transfection agents studied by ESR spectroscopy
Keywords: DNA transfection; Electron Spin Resonance; Lipoplexes; Triazine surfactants; Disulfide bond;
Membrane fusion inducers, chloroquine and spermidine increase lipoplex-mediated gene transfection
Keywords: Gene transfection; Lipoplexes; Lipofectamine; Chlorpromazine; Procainamide; Chloroquine; Spermidine
mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
Keywords: Delivery; mRNA; Cationic carriers; Lipoplexes; Polyplexes
Assessment of siRNA pharmacokinetics using ELISA-based quantification
Keywords: siRNA; Quantification; ELISA; Chemical modification; Pharmacokinetics; Lipoplexes
Patterned transgene expression in multiple-channel bridges after spinal cord injury
Keywords: Spatial patterning; Gene therapy; Spinal cord; Regenerative medicine; Lipoplexes
Non-viral gene delivery carrier and its three-dimensional transfection system
Keywords: Non-viral vector; Gene delivery; Polyplexes; PEI; Lipoplexes; Three-dimensional scaffolds
Gene delivery by lipoplexes and polyplexes
Keywords: Gene therapy; Intracellular fate; Lipoplexes; Polyplexes; Cationic lipid; Cationic polymer; DNA dissociation; Non-bilayer phase
Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice
Keywords: Plasmid DNA; Cationic lipids; Lipoplexes; Cytokine; Liver injury