Keywords: لیتیوم دی ایزوپروپیل امید; ADME-Tox; absorption, distribution, metabolism, excretion, and toxicity; AUC; area under the curve; BnSH; benzyl mercaptan; Xantphos; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; CYP2C19; hepatic cytochrome P450 2C19; CYP3A4; hepatic cytochrome P450 3
مقالات ISI لیتیوم دی ایزوپروپیل امید (ترجمه نشده)
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Keywords: لیتیوم دی ایزوپروپیل امید; ADME-Tox; absorption, distribution, metabolism, excretion, and toxicity; CYP2C19; hepatic cytochrome P450 2C19; CYP3A4; hepatic cytochrome P450 3A4; DSC; differential scanning calorimetry; DIBAL-H; diisobutylaluminium hydride; DME; 1,2-dimethoxyethane; DM
Keywords: لیتیوم دی ایزوپروپیل امید; Nitro compounds; Natural products; Pharmaceuticals; Stereoselective synthesis; Organocatalysis; Metal catalysis; Nitronates; Nitrile oxides; AIBN; azobisisobutyronitrile; AZADO; 2-azaadamantane-N-oxyl; 9-BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,2â²-bis(
Keywords: لیتیوم دی ایزوپروپیل امید; Phthalocyanine; Low temperature synthesis; Lithium diisopropylamide;
Keywords: لیتیوم دی ایزوپروپیل امید; Ac; acetyl; acac; acetylacetonate; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butyloxycarbonyl; BOM; benzyloxymethyl; brsm; based on recovered starting material; Bz; benzoyl; CAN; ammonium cerium(IV) nitrate; Cbz; benzyloxycarbonyl; CD; circ
Discovery of orally bioavailable cyclohexanol-based NR2B-selective NMDA receptor antagonists with analgesic activity utilizing a scaffold hopping approach
Keywords: لیتیوم دی ایزوپروپیل امید; AcOEt; ethyl acetate; chloramine-T; N-chloro 4-methylbenzenesulfonamide sodium salt; DMAP; N,N-4-dimethylaminopyridine; DMF; N,N-dimethylformamide; hERG; human Ether-a-go-go Related Gene; HOBt; 1-hydroxybenzotriazole; IBX; o-iodoxybenzoic acid; LDA; lithi
Stereoselective synthesis of modified cysteines
Keywords: لیتیوم دی ایزوپروپیل امید; Alloc; allyloxycarbonyl; Ar; aryl; Bn; benzyl; Cbz; benzyloxycarbonyl; Cbz-OSu; benzyloxycarbonylsuccinimide; NBS; N-bromosuccinimide; Boc; tert-butoxycarbonyl; m-CPBA; m-chloroperbenzoic acid; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBU; 1,8-diazabicyclo[5
Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2â²-piperidin)-1-ones as potassium-competitive acid blockers
Keywords: لیتیوم دی ایزوپروپیل امید; dppf; 1,1â²-bis(diphenylphosphino)ferrocene; Xphos; 2-dicyclohexylphosphino-2â²,4â²,6â²-triisopropylbiphenyl; DMF; N,N-dimethylformamide; GERD; gastroesophageal reflux disease; HPLC; high-performance liquid chromatography; LDA; lithium diisopropylamid
Acyclic diene metathesis polymerization: History, methods and applications
Keywords: لیتیوم دی ایزوپروپیل امید; ADMET; acyclic diene metathesis; ATRP; atom transfer radical polymerization; DAST; diethylaminosulfur trifluoride; DMF; dimethylformamide; DSC; differential scanning calorimetry; EH; ethylene/1-hexene copolymer; EP; ethylene/propylene copolymer; EtAlCl2;
Multidentate N-heterocyclic carbene complexes of the 3d metals: Synthesis, structure, reactivity and catalysis
Keywords: لیتیوم دی ایزوپروپیل امید; δ; Chemical shift; 1D; One dimension; 2D; Two dimensions; Ac; Acetate; Acac; Acetylacetonate; Ad; Adamantyl; Ar; Aryl; BARF; Tetrakis(3,5-di-trifluoromethylphenyl)borate); Bipy; 2,2â²-bipyridine; Bu; Butyl; Bn; Benzyl; COD; Cyclooctadiene; COE; Cyclooct
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development
Keywords: لیتیوم دی ایزوپروپیل امید; Translocator protein; PET; Carbon-11; Ligand; Binding affinity; Lipophilic efficiency; DIPEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; HFIP; hexafluoroisopropyl alcohol; HRMS-ESI; high resolution mass spectrometry electr
Achievement of regioselectivity in transition metal-catalyzed direct C-H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups
Keywords: لیتیوم دی ایزوپروپیل امید; Chemoselectivity; Regioselectivity; Direct C-H (hetero)arylation; Transition metal catalysts; Removable groups; Traceless directing groups; Deprotection; Ac; acetyl; acac; acetylacetonate; 1-Ad; 1-adamantyl; AIBN; azobisisobutyronitrile; Ar; aryl; Boc;
Stereoselective synthesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors
Keywords: لیتیوم دی ایزوپروپیل امید; HMG-CoA reductase inhibitors; Statins; Chiral β-hydroxy-δ-lactone; Chiral 3,5-syn-diol acid; Asymmetric synthesis; Ac; acetyl; Ar; aryl; Bn; benzyl; Bz; benzoyl; n-Bu; butyl; t-Bu; tert-butyl; CDI; 1,1â²-carbonyldiimidazole; BINOL; 1,1â²-bi-2-naphthol
An update on the stereoselective synthesis of α-aminophosphonic acids and derivatives
Keywords: لیتیوم دی ایزوپروپیل امید; α-Aminophosphonic acids; α-Aminophosphonates; Stereoselective synthesis; Three-component reaction; ABSA; 4-acetamidobenzenesulfonyl azide; Abu; aminobutyric acid; Ac; acetyl; ACE; angiotensin-converting enzyme; Ala; alanine; Ar; aryl; BINAP; 2,2â²-bis(
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3
Keywords: لیتیوم دی ایزوپروپیل امید; ADT; androsterone; AR; androgen receptor; Ar; aryl group; DBD; DNA binding domain; DCM; dichloromethane; DHT; dihydrotestosterone; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; Î4-dione; 4-androstene-3,17-dione; EtOAc
Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels
Keywords: لیتیوم دی ایزوپروپیل امید; 2D NOESY; two-dimensional nuclear Overhauser effect spectroscopy; Dibal-H; diisobutylaluminum hydride; DRG; dorsal root ganglion; ee; enantiomeric excess; ET-1; endothelin-1; ETA; endothelin A receptors; EGTA; ethylene glycol tetraacetic acid; EC50; media
Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives
Keywords: لیتیوم دی ایزوپروپیل امید; AcOH; acetic acid; Boc; tert-butyloxycarbonyl; CCL2; chemokine ligand 2; CCR2; chemokine receptor 2; DCE; dichloroethane; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMAP; N,N-dimethylaminopyridine; DMSO; dimethylsulfoxide; INCB3344; N-(2-(((3
Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents
Keywords: لیتیوم دی ایزوپروپیل امید; SK; streptokinase; GAS; Group A Streptococcus; HTS; high-throughput screen; SAR; structure-activity relationship; TPSA; topological polar surface area; c Log P; logarithm of the calculated octanol-water partition coefficient; LDA; lithium diisopropy
Proteasome inhibitors for cancer therapy
Keywords: لیتیوم دی ایزوپروپیل امید; BOP; (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; DMSO; dimethyl sulfoxide; HMPA; hexamethyl phosphoramide; HOBt; 1-hydroxybenzotriazole; NMM; N-methylmorpholine; DMF; N,N-dimethyformamide; LDA; lithium diisopropylamide; THF;
Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain
Keywords: لیتیوم دی ایزوپروپیل امید; AMP; adenosine monophosphate; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; cGMP; cyclic guanosine monophosphate; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; GMP; guanosine monophosphate; HD; Huntington disease; LDA; lithium
Recent developments in dynamic kinetic resolution
Keywords: لیتیوم دی ایزوپروپیل امید; Ac; acetyl; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; Atm; atmosphere; BARF; tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; BINAP; 2,2â²-bis(diphenylphosphanyl)-1,1â²-binaphthyl; BINOL; 1,1â²-bi-2-naphthol; BIPHEP; 2,2â²-bis(diphenylphosphino)-1
An efficient synthesis of 3-aryl-2-aryl(or methyl)sulfanylbenzo[b]thiophenes via cyclization of aryl 2-aryl(or methyl)sulfanylmethylsulfanylphenyl ketones
Keywords: لیتیوم دی ایزوپروپیل امید; Benzo[b]thiophenes; 2-Sulfanylphenyl ketones; Lithium diisopropylamide; Cyclization; Dehydration;
Occurrence, biological activity and synthesis of cheilanthane sesterterpenoids
Keywords: لیتیوم دی ایزوپروپیل امید; Cheilanthanes; Sesterterpenoids; Marine natural products; Synthesis; Ac; acetyl; n-Bu; n-butyl; CSA; camphorsulfonic acid; m-CPBA; m-chloroperbenzoic acid; DBU; 1,8-diazobicyclo[5.4.0]undec-7-ene; DCC; 1,3-dicyclohexylcarbodiimide; DHP; 3,4-dihydro-2H-pyr
Synthesis of cyclonucleosides having a C-C bridge
Keywords: لیتیوم دی ایزوپروپیل امید; Ac; acetyl; AIBN; azobisisobutyronitrile (2,2â²-azobis(2-methylpropionitrile)); An; anisyl; BOM; benzyloxymethyl; Bu; butyl; Bz; benzoyl; CAN; ceric ammonium nitrate; DBU; diazadicycloundecane; DCC; dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine
Advances in the Baylis-Hillman reaction-assisted synthesis of cyclic frameworks
Keywords: لیتیوم دی ایزوپروپیل امید; Baylis-Hillman reaction; Cyclic compounds; Heterocycles; Nucleophilic substitution; Ac; acetyl; AIBN; 2,20-azobisisobutyronitrile; Aq; aqueous; Ar; aryl; 9BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,20-bis(diphenylphosphanyl)-1,10-binaphthyl; BF3·Et2O; b
Intramolecular 1,3-dipolar cycloaddition reactions in targeted syntheses
Keywords: لیتیوم دی ایزوپروپیل امید; Intramolecular 1,3-dipolar cycloaddition; Huisgen reaction; 1,3-Dipole; Azomethine ylide; Azomethine imine; Carbonyl ylide; Nitrile oxide; Azide; Nitrone; Mesionic compound; Betaine; Natural product synthesis; Alkaloid; Ac; acetyl; aq; aqueous; Boc; terti
Stereoselective syntheses of naturally occurring 5,6-dihydropyran-2-ones
Keywords: لیتیوم دی ایزوپروپیل امید; Naturally occurring 5,6-dihydropyran-2-ones; 5,6-Dihydro-α-pyrones; Stereoselective synthesis; Ad; adamantyl; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthalene; BINOL; 1,1â²-bi(2-naphthol); B.Y.; baker's yeast; Bn; benzyl; Bz; benzoyl; Car; 2-ca
Enantioselective synthesis of steroids
Keywords: لیتیوم دی ایزوپروپیل امید; Steroids; Asymmetric inductions; Pool chiral; Enantioselectivity; Resolution; acac; acetylacetonate; 9-BBN; 9-bora-bicyclo[3.3.1]nonane; BHT; 2,6-di-tert-butyl-4-methylphenol; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthyl; Binol; 1,1â²-binaphtha
Recent advances in the chemistry of triaryl- and triheteroarylmethanes
Keywords: لیتیوم دی ایزوپروپیل امید; Triarylmethanes; Triheteroarylmethanes; Ar; aryl; Bt; benzotriazolyl; CAN; cerium(IV) ammonium nitrate; DDQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; DME; 1,2-dimethoxyethane; DMSO; dimethylsulfoxide; ISC; inter system crossing; INDO; intermediate negle
Recent advances in the chemistry of macroline, sarpagine and ajmaline-related indole alkaloids
Keywords: لیتیوم دی ایزوپروپیل امید; Ac; acetyl; AD; asymmetric dihydroxylation; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butoxycarbonyl; Bu; butyl; Bz; benzoyl; cat; catalytic; CBz; benzyloxycarbonyl; CLB; chlorobenzoyl; Cy; cyc
The chemistry of recently isolated naturally occurring quinazolinone alkaloids
Keywords: لیتیوم دی ایزوپروپیل امید; Natural quinazolinones; Isolation; Bioactivity; Synthesis; Concise account; 1983-2005; AIBN; 2,2â²-azobisisobutyronitrile; Bn; benzyl; Boc; tert-butoxycarbonyl; BOP; benzotriazol-1-yloxytris(dimethylamino)-phosphoniumhexaflurophosphate; CAN; ceric ammo
Use of chiral sulfoxides in asymmetric synthesis
Keywords: لیتیوم دی ایزوپروپیل امید; Ac; acetyl; Acac; acetylacetone; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; BF3·Et2O; boron trifluoride etherate; BINAP; 2,2â²-bis(diphenylphosphanyl)-1,1â²-binaphthyl; Bn; benzyl; Boc; tert-butoxycarbonyl; Born; borneol; Bu; butyl; Cbz; benzyloxyc
A synthon approach to spiro compounds
Keywords: لیتیوم دی ایزوپروپیل امید; Photochromism; Synthon; Spiro compounds; BINAP; 2,2â²-bis(diphenylphospospiro)-1,1â²-binaphthalene; Boc; t-butoxycarbonyl; CTAB; cetyltrimethylammonium bromide; DEAD; diethylazodicarboxylate; 4-DMAP; 4-(dimethylamino)pyridine; Fmoc; 9-fluorenylmethoxyca
Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid
Keywords: لیتیوم دی ایزوپروپیل امید; GABA-uptake inhibitors; Antiepileptic; GAT-1; GAT-3; Pyrrolidines; Bn; benzyl; Cbz; benzyl carboxylate; CC; column chromatography; DEAD; diethyl azodicarboxylate; DMAP; (4-dimethylamino)pyridine; GAT; GABA transport protein; LDA; lithium diisopropylamide;
Acyclic α-nitro ketones: a versatile class of α-functionalized ketones in organic synthesis
Keywords: لیتیوم دی ایزوپروپیل امید; α-Nitro ketones; Acyclic; Organic synthesis; AIBN; azobisisobutyronitrile; ALA-5; δ-aminolevulinic acid; CIMP; 2-chloro-5-iodomethylpyridine; DBU; 1,8-diazobicyclo[5.4.0]undec-7-ene; DCC; dicyclohexylcarbodiimide; DHRGC; dynamic high-resolution gas chro
Dithienothiophenes
Keywords: لیتیوم دی ایزوپروپیل امید; Thiophene; Dithienothiophene; CA; chloranil; CV; cyclic voltammetry; DDQ; 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; DMeDTT; dimethyldithienothiophene; DMF; N,N-dimethylformamide; ESR; electron spin resonance; LDA; lithium diisopropylamide; LED; light-emi
Naphtho[2,3-c]furan-4,9-diones and related compounds: theoretically interesting and bioactive natural and synthetic products
Keywords: لیتیوم دی ایزوپروپیل امید; Naphtho[2,3-c]furan-4,9-diones; Naphtho[2,3-c]furan-4(9H)-ones; Naphtho[2,3-c]furan; Isofuranonaphthoquinones; Ac; acetyl; AIBN; 2â²-azobis(isobutyronitrile); Ar; aryl; Bn; benzyl; BOM; benzyloxymethyl; But; tert-butyl; CSA; camphor-10-sulfonic acid; DBU
Synthetic approaches to the 2012 new drugs
Keywords: لیتیوم دی ایزوپروپیل امید; 1,2-DAP; 1,2-diaminopropane; 1,2-DCE; 1,2-dichloroethane; Ac; acetyl; aq; aqueous; B2(pin)2; bis(pinacolato)diboron; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthyl; BOP; benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophospate; CDI; N
Synthesis and applications of tetrathiafulvalenes and ferrocene-tetrathiafulvalenes and related compounds
Keywords: لیتیوم دی ایزوپروپیل امید; 1,3-Dithiole ring; Ferrocene; Coulombic repulsion; Electron donors; Tetrathiafulvalenes; CT-complexes; Superconductors; BEDT-TTF; bisethylendithia-tetrathiafulvalene; BMT-TTF; bismethylthio-tetrathiafulvalene; CT; charge-transfer; CV; cyclic voltammetry;
Use of O-glycosylation in total synthesis
Keywords: لیتیوم دی ایزوپروپیل امید; O-Glycosylation; Total synthesis; Ac; acetyl; ACF; activated carbon fiber; AIBN; 2,2â²-azobiisobutyronitrile; Alloc; allyloxycarbonyl; Ar; aryl; AtOH; 7-aza-1-hydroxy-1H-benzotriazole; BF3(Et2O); boron trifluoride etherate; DMB; 3,4-dimethoxybenzyl; DMTS