Upregulation of long non-coding RNA RAB1A-2 induces FGF1 expression worsening lung cancer prognosis
Keywords: Lung cancer; lncRNA; Lnc-RAB1A-2; FGF1; Survival;
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Long non-coding RNAs in the failing heart and vasculature
Keywords: lncRNA; Cardiac disease; Hypertrophy; Fibrosis; Inflammation; Endothelial dysfunction; Ageing;
Biology and clinical relevance of noncoding sno/scaRNAs
Keywords: Noncoding RNA; Small Cajal body-associated RNA; Spliceosomal RNA; Small nucleolar RNA; Alternative splicing; AGO; argonaute; CLL; chronic lymphocytic leukemia (CLL); CB; Cajal body; CTD; carboxyl-terminal domain; DC; Dyskeratosis congenital; DKC1; Dyskera
FGF2 and FAM201A affect the development of osteonecrosis of the femoral head after femoral neck fracture
Keywords: ONFH; osteonecrosis of the femoral head; FNF; femoral neck fracture; DEGs; differentially expressed genes; PPI; protein-protein interaction; VEGF; vascular endothelial growth factor; HIF-1α; hypoxia-inducible factor-1 alpha; OPG; osteoprotegerin; RANK; r
A multi-omics analysis of the regulatory changes induced by miR-223 in a monocyte/macrophage cell line
Keywords: CARM-1; coactivator-associated arginine methyltransferase 1; Cic; Capicua transcriptional repressor; CKD; chronic kidney disease; DMEM; Dulbecco's Modified Eagle's Medium; FCS; foetal calf serum; FDR; false discovery rate; FID; free induction decay values
Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90
Keywords: Adar; RNaseL; Lupus; Heat shock; Epigenetics; Histone deacetylase inhibitor; 17-AAG; 17-Demethoxy-17-(2-propenylamino) geldanamycin; APOBEC; Apolipoprotein B mRNA Editing Enzyme Catalytic Polypeptide-Like; ERV; Endogenous retrovirus; H3K4me3; Histone 3, l
Up-regulated BCAR4 contributes to proliferation and migration of cervical cancer cells
Keywords: LncRNA; BCAR4; Cervical cancer;
Analysis of long non-coding RNA expression profiles using RNA sequencing in ovarian endometriosis
Keywords: GO; Gene Ontology; BP; biological process; CC; cellular component; MF; molecular function; KEGG; Kyoto Encyclopedia of Genes and Genomes; CNC network; coding-non-coding gene co-expression network; CNCI; Coding-Non-Coding-Index; CPC; Coding Potential Calcu
Long noncoding RNA DANCR mediates cisplatin resistance in glioma cells via activating AXL/PI3K/Akt/NF-κB signaling pathway
Keywords: Long noncoding RNA; Glioma; Cisplatin; Chemoresistance; PI3K/Akt/NF-κB signaling pathway; lncRNA; long noncoding RNA; miRNAs; microRNAs; DANCR; differentiation antagonizing non-protein coding RNA; qPCR; quantitative polymerase chain reaction; TUNEL; TdT-
Long non-coding RNA SNHG15 interacts with and stabilizes transcription factor Slug and promotes colon cancer progression
Keywords: LncRNA; Slug; EMT; Colon cancer; SNHG15;
Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells
Keywords: AmA; antimycin A; AMPK; adenosine monophosphate-activated protein kinase; CoQ; coenzyme Q10; DCF; 2â²,7â²-dichlorofluorescin; DCFH-DA; 2â²,7â²-dichlorofluorescin diacetate; ddPCR; droplet digital PCR; ETS; electron transfer system; FBS; fetal bovine s
A novel brown adipocyte-enriched long non-coding RNA that is required for brown adipocyte differentiation and sufficient to drive thermogenic gene program in white adipocytes
Keywords: BAT; brown adipose tissue; WAT; white adipose tissue; ETC; electron transport chain; Ucp1; uncoupling protein 1; Cebpα/β/δ; CCAAT/enhancer-binding proteins α/β/δ; Pparγ; peroxisome proliferator-activated receptor gamma; Pgc1α; Pparγ coactivator 1
LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma
Keywords: lncRNA; long non-coding RNA; HCC; hepatocellular carcinoma; SOX9; SRY-related HMG-box gene 9; miRNA; microRNA; qRT-PCR; quantitative real-time polymerase chain reaction; IDVs; integrated light density values; HCC; LINC00052; SOX9; miR-101-3p; Proliferatio
HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo
Keywords: PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM
Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2
Keywords: Anti-DIG; antibody against digoxigenin; APES; 3-aminopropyl-triethoxysilane; ARE; antioxidant response element; BSA; bovine serum albumin; CNC; coding-non-coding; Cy3; cyanine dye 3; DA; dopamine; DAPI; 4,6-diamidino-2-phenylindole; DEPC; Diethyl pyrocarb
The emerging role of exosome-derived non-coding RNAs in cancer biology
Keywords: Exosomes; MVBs; Tumor; miRNA; lncRNA;
Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U
Keywords: LncRNA; HAND2-AS1; HAND2; NMU; Promoter hypermethylation; Endometrial carcinoma; EEC; Endometrioid endometrial carcinoma; lncRNAs; long noncoding RNAs; NE; normal endometrium; HAND2; Heart and Neural Crest Derivatives Expressed 2; NMU; neuromedin U;
Expression profiles of mRNA and long noncoding RNA in the ovaries of letrozole-induced polycystic ovary syndrome rat model through deep sequencing
Keywords: PCOS; polycystic ovary syndrome; lncRNA; long noncoding RNA; IR; insulin resistance; T2D; type 2 diabetes; ceRNA; competing endogenous RNA; miRNA; microRNA; DAPK1; death-associated protein kinase 1; H&E; Hematoxylin and eosin; FSH; follicle-stimulating ho
Research paperThe long non-coding RNA MIAT regulates zinc finger E-box binding homeobox 1 expression by sponging miR-150 and promoteing cell invasion in non-small-cell lung cancer
Keywords: ZEB1; zinc finger E-box binding homeobox 1; NSCLC; non-small-cell lung cancer; lncRNA; long non-coding RNA; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide; Lung cancer; MIAT; miRNA-150; Zinc finger E-box binding homeobox 1;
Non-coding RNAs and Berberine: A new mechanism of its anti-diabetic activities
Keywords: Berberine; Diabetes; MiRNA; LncRNA;
ARID1A represses hepatocellular carcinoma cell proliferation and migration through lncRNA MVIH
Keywords: ARID1A; SWI/SNF chromatin remodeling complex; lncRNA; Hepatocellular carcinoma; MVIH;
Genetic polymorphisms in long noncoding RNA H19 are associated with breast cancer susceptibility in Iranian population
Keywords: Long noncoding RNA; LncRNA; H19; Polymorphism; Breast cancer; Susceptibility;
Inhibition of long noncoding RNA IGF2AS promotes angiogenesis in type 2 diabetes
Keywords: Type 2 diabetes; lncRNA; IGF2AS; IGF2; IGF1; VEGF;
Long noncoding RNA linc00346 promotes the malignant phenotypes of bladder cancer
Keywords: Bladder cancer; lncRNA; Proliferation; Invasion;
Inhibition of miR-664a interferes with the migration of osteosarcoma cells via modulation of MEG3
Keywords: lncRNA; MEG3; miRNA; miR-664a; Osteosarcoma;
Highly expressed long non-coding RNA FOXD2-AS1 promotes non-small cell lung cancer progression via Wnt/β-catenin signaling
Keywords: lncRNA; FOXD2-AS1; NSCLC; Wnt/β-catenin signaling;
Long intergenic noncoding RNA 00305 sponges miR-136 to regulate the hypoxia induced apoptosis of vascular endothelial cells
Keywords: Vascular endothelial cells; lncRNA; LINC00305; miR-136; Apoptosis;
ArticleA long noncoding RNA involved in rice reproductive development by negatively regulating osa-miR160
Keywords: microRNA; lncRNA; miR160; Target mimic;
Expression profile of lncRNA in human bronchial epithelial cells response to Talaromyces marneffei infection: A microarray analysis
Keywords: lncRNA; Microarray analysis; Fungus; Human bronchial epithelial cell;
Research Techniques Made Simple: Identification and Characterization of Long Noncoding RNA in Dermatological Research
Keywords: cSCC; cutaneous squamous cell carcinoma; FISH; fluorescence in situ hybridization; lncRNA; long noncoding RNA; PICSAR; p38 inhibited cutaneous squamous cell carcinoma associated lincRNA; RNA-seq; RNA sequencing; TINCR; tissue differentiation-inducing non-
Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression
Keywords: GWA studies; genome-wide association studies; SNP; single nucleotide polymorphism; MDD; major depressive disorder; TAS; trait/disease-associated SNP; lncRNA; long noncoding RNA; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders Fourth Edition;
Viral lncRNA: A regulatory molecule for controlling virus life cycle
Keywords: lncRNA; Viral life cycle; Gene regulation; Viral replication; Virus intervention;
Transcriptome analysis of EGFR tyrosine kinase inhibitors resistance associated long noncoding RNA in non-small cell lung cancer
Keywords: NSCLC; EGFR-TKIs; Resistant; lncRNA;
Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A
Keywords: PCAT-1; Prostate cancer-associated transcript1; DMSO; Dimethyl sulfoxide; FCM; Flow cytometry; PBS; Phosphate-buffered saline; PCAT-1; Gastric cancer; CDKN1A; lncRNA;
Inhibition of long non-coding RNA IGF2AS protects apoptosis and neuronal loss in anesthetic-damaged mouse neural stem cell derived neurons
Keywords: lncRNA; IGFAS; Ketamine; Neurotoxicity; Neural stem cell;
An increased expression of long non-coding RNA PANDAR promotes cell proliferation and inhibits cell apoptosis in pancreatic ductal adenocarcinoma
Keywords: Pancreatic ductal adenocarcinoma; lncRNA; PANDAR; Prognosis;
LncRNA Gm4419 contributes to OGD/R injury of cerebral microglial cells via IκB phosphorylation and NF-κB activation
Keywords: lncRNA; Gm4419; Microglial cells; OGD/R; NF-κB pathway;
The LncRNA ZBED3-AS1 induces chondrogenesis of human synovial fluid mesenchymal stem cells
Keywords: Human synovial fluid-derived mesenchymal stem cell; lncRNA; ZBED3-AS1;
Systematic identification of cancer-related long noncoding RNAs and aberrant alternative splicing of quintuple-negative lung adenocarcinoma through RNA-Seq
Keywords: LUAD; lung adenocarcinoma; lncRNA; long noncoding RNA; ACRG; Asian Cancer Research Group; qPCR; quantitative real-time polymerase chain reaction; BH; Benjamini-Hochberg; FDR; false discover rate; FC; fold change; A3SS; alternative 3â² splice sites; A5SS;
Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus
Keywords: EU358092; lncRNA; microRNA-137; Schizophrenia;
LncRNA HOTAIR alleviates rheumatoid arthritis by targeting miR-138 and inactivating NF-κB pathway
Keywords: HOTAIR; Rheumatoid arthritis; Proliferation; Inflammation; miR-138; NF-κB signaling pathway; RA; rheumatoid arthritis; miR; microRNA; lncRNA; long non-coding RNA; PCNA; proliferating cell nuclear antigen; IL; interleukin; NF-κB; nuclear transcription fa
Long non-coding RNA CASC2 in human cancer
Keywords: CASC2; lncRNA; Cancer; Oncogenesis; Oncosuppressor;
Original ArticlePseudogene PDIA3P1 promotes cell proliferation, migration and invasion, and suppresses apoptosis in hepatocellular carcinoma by regulating the p53 pathway
Keywords: Long noncoding RNA; Pseudogene; Hepatocellular carcinoma; p53; HCC; hepatocellular carcinoma; LncRNA; long noncoding RNA; PDIA3P1; protein disulfide isomerase family A member 3 pseudogene 1; SiRNA; short interfering RNA; ShRNA; short hairpin RNA; qRT-PCR;
Cyclophosphamide promotes the proliferation inhibition of mouse ovarian granulosa cells and premature ovarian failure by activating the lncRNA-Meg3-p53-p66Shc pathway
Keywords: OGCs; ovarian granulosa cells; POF; premature ovarian failure; lncRNA; long non-coding RNA; Meg3; maternally expressed gene 3; ROS; reactive oxygen species; DMEM:F12; Dulbecco's Modified Eagle Medium: Ham's F-12; bFGF; basic fibroblast growth factor; EGF;
A three-lncRNA signature derived from the Atlas of ncRNA in cancer (TANRIC) database predicts the survival of patients with head and neck squamous cell carcinoma
Keywords: lncRNA; Signature; The Atlas of ncRNAs in Cancer; Predict; Survival; Head and neck squamous cell carcinoma;
Original ArticleThe long non-coding RNA 91H increases aggressive phenotype of breast cancer cells and up-regulates H19/IGF2 expression through epigenetic modifications
Keywords: H19 antisense; Long non-coding RNA; Breast tumorigenesis; Genomic imprinting; lncRNA; long non-coding RNA; ICR; imprinting Control Region; CTCF; CCTC-binding factor; TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labeling; ChIP; chromatin-immu
Research paperNovel spliced variants of OCT4, OCT4C and OCT4C1, with distinct expression patterns and functions in pluripotent and tumor cell lines
Keywords: lncRNA; PSORS1C3; Stem cell; Differentiation; OCT4C; OCT4C1;
Mammalian microRNAs and long noncoding RNAs in the host-bacterial pathogen crosstalk
Keywords: Host-pathogen; Bacteria; microRNA; lncRNA; Regulatory network;
Analyses of long non-coding RNAs and mRNA profiling through RNA sequencing of MDBK cells at different stages of bovine viral diarrhea virus infection
Keywords: BVDV; Bovine viral diarrhea virus; CNCI; Coding-Non-Coding-Index; CPC; Coding Potential Calculator; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; FPKMs; fragments per kilobase of transcript sequences per million base pairs sequenced;
Long non-coding RNA UC001kfo promotes hepatocellular carcinoma proliferation and metastasis by targeting α-SMA
Keywords: lncRNA; long non-coding RNA; HCC; hepatocellular carcinoma; EMT; epithelial-mesenchymal transition; FBS; fetal bovine serum; BSA; bovine serum albumin; Hepatocellular carcinoma; UC001kfo; Proliferation; Metastasis; α-SMA;