Keywords: LOX، لیپوکسیژناز; Eosinophil; Lipid mediator; Lipidomics; Lipoxygenase; n-3 fatty acidPUFA, polyunsaturated fatty acid; LC-MS/MS, liquid chromatography tandem mass spectrometry; COX, cyclooxygenase; LOX, lipoxygenase; CYP, cytochrome P450; HETE, hydroxy-eicosatetraenoic ac
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Keywords: LOX، لیپوکسیژناز; AAPH, 2,2′-azobis(2-amidinopropane) dihydrochloride; DPPP, diphenyl-1-pyrenylphosphine; FI, fluorescence intensity; LOX, lipoxygenase; MeO-AMVN, 2,2′-azobis-(4-methoxy-2,4-dimethyllvaleronitrile); NDGA, nordihydroguaiaretic acid; SIN-1, 3-morpholinosydnon
Keywords: LOX، لیپوکسیژناز; HOT(D)E, hydroxyoctadecatri(di)enoic acid; HPOT(D)E, hydroperoxyoctadecatri(di)enoic acid; KC, kinetically-controlled; KODE, keto-octadecadienoic acid; LA, linoleic acid; LNA, linolenic acid; LOX, lipoxygenase; PLAT, Polycystin-1, Lipoxygenases and Alpha
Keywords: LOX، لیپوکسیژناز; AA, arachidonic acid; EPA, 5,8,11,14,17-eicosapentaenoic acid; DHA, 4,7,10,13,16,19-docosahexaenoic acid; LOX, lipoxygenase; COX, cyclooxygenase; PG, prostaglandins; Tx, thromboxane; cPLA2, cytosolic phospholipase 2; LTA4H, leukotriene A4 hydrolase; LTC4S
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; hLOX, human lipoxygenase; h15-LOX-2, human epithelial 15-lipoxygenase-2; h15-LOX-1, human reticulocyte 15-lipoxygenase-1; h12-LOX, human platelet 12-lipoxygenase; s15-LOX-1, soybean 15-lipoxygenase-1; h5-LOX, human leukocyte 5-lipoxygen
Keywords: LOX، لیپوکسیژناز; AOS2, allene oxide synthase 2; EDS1, enhanced disease susceptibility 1; EIN2, ethylene insensitive 2; ET, ethylene; hpi, hours post-infestation; JA, jasmonic acid; LOX, Lipoxygenase; NPR1, nonexpressor of pathogenesis-related genes 1; PAD4, phytoalexin de
Keywords: LOX، لیپوکسیژناز; CA, cold acclimated; CAT, catalase; DBI, double bond index; ELI, electrolyte leakage index; FAs, fatty acids; FM, fresh mass; GC, gas chromatography; GPX, guaiacol peroxidase; JA, jasmonic acid; LOX, lipoxygenase; MDA, malondialdehyde; NA, non-acclimated;
Separation of enzymatic functions and variation of spin state of rice allene oxide synthase-1 by mutation of Phe-92 and Pro-430
Keywords: LOX، لیپوکسیژناز; AOS, allene oxide synthase; AOC, allene oxide cyclase; LOX, lipoxygenase; HPL, hydroperoxide lyase; HPOD, hydroperoxydienoic acid; HPOT, hydroperoxytrienoic acid; EOD, 12,13-epoxy-9,11-octadecadienoic acid; EOT, 12,13-epoxy-9,11,15-octadecatrienoic acid;
A potent and selective inhibitor targeting human and murine 12/15-LOX
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; hLOX, human lipoxygenase; h15-LOX-2, human epithelial 15-lipoxygenase-2; h12/15-LOX, h15-LOX-1, human reticulocyte 15-lipoxygenase-1; h12-LOX, human platelet 12-lipoxygenase; s15-LOX-1, soybean 15-lipoxygenase-1; h5-LOX, human leukocyte
Relationships between free and esterified fatty acids and LOX-derived volatiles during ripening in apple
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; TLC, thin layer chromatograph; GC-FID, gas chromatograph-flame ionization detector; FFA, free fatty acid; FAME, fatty acid methyl esterFree fatty acid; Polar lipid; Aldehyde; LOX; Ester; Aroma; Flavor
Phytomedicine polypharmacology: Cancer therapy through modulating the tumor microenvironment and oxylipin dynamics
Keywords: LOX، لیپوکسیژناز; AA, arachidonic acid; COX, cyclooxygenase; CYP, cytochrome P450; HETEs, hydroxyeicosatetraenoic acids; LOX, lipoxygenase; MAPK, mitogen-activated protein kinase; MDSCs, myeloid-derived suppressor cells; NF-κB, nuclear factor-kappa B; NO, nitric oxide; PGE
Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase
Keywords: LOX، لیپوکسیژناز; Anti-inflammation; Arachidonic acid; Bilirubin dimethyl ester; Phospholipase A2; Unconjugated bilirubinAA, arachidonic acid; BD1, dimethyl ester of bilirubin; COX, cyclooxygenase; LOX, lipoxygenase; HSF, human synovial fluid; sPLA2IIA, secretory phospholi
Modulation of LOX and COX pathways via inhibition of amyloidogenesis contributes to mitoprotection against β-amyloid oligomer-induced toxicity in an animal model of Alzheimer's disease in rats
Keywords: LOX، لیپوکسیژناز; AA, arachidonic acid; AChE, acetylcholinesterase; AD, Alzheimer's disease; APP, amyloid precursor protein; COX, cyclooxygenase; ELT, escape latency time; ICV, intracerebroventricular; LOX, lipoxygenase; MDA, malondialdehyde; MWM, Morris water-maze; NSAID,
Ethylene-induced water soaking in Dendrobium floral buds, accompanied by increased lipoxygenase and phospholipase D (PLD) activity and expression of a PLD gene
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; MDA, malondialdehyde; 1-MCP, 1-methylcyclopropene; PA, phosphatidic acid; PCD, programmed cell death; PLD, phospholipase DEnzyme activity; Floral buds; Gene expression; Lipoxygenase; Phospholipase D
System study of MPO promoter high-frequency polymorphic variants on transcription factor network
Keywords: LOX، لیپوکسیژناز; MPO, myeloperoxidase; MYB, v-myb avian myeloblastosis viral oncogene homolog; FOS, FBJ murine osteosarcoma viral oncogene homolog; NOX, NAD(P)H oxidase; XO, xanthine oxidase; NOS, nitric oxide synthase; LOX, lipoxygenase; CAD, coronary artery disease; PPI
Partial clarification of signaling pathway of taxanes increase biosynthesis by low intensity ultrasound treatment in hazel (Corylus avellana) cells
Keywords: LOX، لیپوکسیژناز; DXP, 1-deoxy-d-xylulose-5-phosphate; DXR, 1-deoxy-d-xylulose-5-phosphate reductoisomerase; DXS, DXP synthase; GAP, glyceraldehyde-3-phosphate; IPP, isopenthenyldiphosphate; LOX, Lipoxygenase; LSD, least significant difference; MEP, 2-Cmethyl-d-erythritol-
Molecular cloning and sequence analysis of lipoxygenase (AsLOX1) gene in Aquilaria sinensis (Lour.) Gilg and its expression responding to MeJA and crush wounding treatment
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; AsLOX1, Aquilaria sinensis lipoxygenase gene; PCR, polymerase chain reaction; RT, reverse transcription; qRT-PCR, real time PCR; RACE, rapid-amplification of cDNA ends; JA, jasmonate; JAs, jasmonates; MeJA, methyl jasmonate; ORF, open r
Cyclooxygenase product inhibition with acetylsalicylic acid slows disease progression in the Han:SPRD-Cy rat model of polycystic kidney disease
Keywords: LOX، لیپوکسیژناز; Polycystic kidney disease; Acetylsalicylic acid; NDGA; EicosanoidCOX, cyclooxygenase; LOX, lipoxygenase; HETE, hydroxyeicosatetraenoic acid; HODE, hydroxyoctadecadienoic acid; PKD, polycystic kidney disease; PG, prostaglandin; TX, thromboxane; ESRD, End s
The peroxidase activity of ADM-Fe3+ cooperates with lipid peroxidation: The participation of hydroperoxide and hydroxyl radicals in the damage to proteins and DNA
Keywords: LOX، لیپوکسیژناز; ADM, adriamycin; COX, cyclooxygenase; DMPO, 5,5-dimethyl-1-pyrroline-1-oxide; HRP, horseradish peroxidase; HO, hydroxyl radical; LOOH, lipid hydroperoxide; LOX, lipoxygenase; TMB, 3,3′,5,5′-tetramethyl-benzidine; TMPD, N,N,N′,N′-tetramethyl-p-phenylene-di
The effects of lupin (Lupinus angustifolius) addition to wheat bread on its nutritional, phytochemical and bioactive composition and protein quality
Keywords: LOX، لیپوکسیژناز; ASL, Australian sweet lupin; DPPH, 2,2-Diphenyl-1-picrylhydrazyl; GAE, Gallic acid equivalents; HPLC, High performance liquid chromatography; IVPD, In vitro protein digestibility; LOX, Lipoxygenase; PDCAAS, Protein digestibility corrected amino acid score
Montelukast potentiates the anticonvulsant effect of phenobarbital in mice: An isobolographic analysis
Keywords: LOX، لیپوکسیژناز; CysLT1, cysteinyl leukotriene receptor 1; PTZ, pentylenetetrazole; COX, cyclooxygenase; LOX, lipoxygenase; LTD4, leukotriene D4; MTK, montelukast; PB, phenobarbital; NaCl, sodium chloride; AED, antiepileptic drug; PGE2, prostaglandine E2; BBB, blood–brain
Salicylic acid alleviates cadmium-induced stress responses through the inhibition of Cd-induced auxin-mediated reactive oxygen species production in barley root tips
Keywords: LOX، لیپوکسیژناز; AAO, ascorbic acid oxidase; DHAR, dehydroascorbate reductase; GPX, glutathione peroxidase; 4-HBA, 4-hydroxybenzoic acid; IAA, indole-3-acetic acid; LOX, lipoxygenase; PCIB, p-chlorophenoxyisobutyric acid; ROS, reactive oxygen species; SA, salicylic acidAu
Resistance to Fusarium verticillioides and fumonisin accumulation in maize inbred lines involves an earlier and enhanced expression of lipoxygenase (LOX) genes
Keywords: LOX، لیپوکسیژناز; dpi, days post inoculation; ET, ethylene; FC, fold change; Fv, Fusarium verticillioides; GLV, green leaf volatile; JA, jasmonic acid; LOX, lipoxygenase; ppm, parts per million; PR, pathogenesis-related; R, resistant CO433 line; S, susceptible CO354 line;
Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15)
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; AA, arachidonic acid; EPA, 5,8,11,14,17-eicosapentaenoic acid; DHA, 4,7,10,13,16,19-docosahexaenoic acid; 13S-H(p)ODE, (13S,9Z,11E)-13-hydro(pero)xyoctadeca-9,11-dienoic acid; 15S-H(p)ETE, (15S,5Z,8Z,11Z,13E)-15-hydro(pero)xyeicosa-5,8,
Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity
Keywords: LOX، لیپوکسیژناز; DPI, diphenyleneiodonium; NAC, N-acetylcysteine; H2O2, hydrogen peroxide; LDH, lactate dehydrogenase; siRNA, small interfering RNAs; AA, arachidonic acid; LOX, lipoxygenase; COX, cyclooxygenase; PLA2, phospholipase A2; LTB4, leukotriene B4; 12(S)-HETE, 12
Probing conformational changes in lipoxygenases upon membrane binding: Fine-tuning by the active site inhibitor ETYA
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; rr 12/15-LOX, rabbit reticulocyte 12/15 lipoxygenase; sb 15-LOX, soybean lipoxygenase 1; GUV, giant unilamellar vesicle; LUV, large unilamellar vesicle; ETP, electron transfer particles; ANS, 8-anilino-1-naphthalenesulfonic acid; ETYA,
Enhanced lipoxygenase activity is involved in the stress response but not in the harmful lipid peroxidation and cell death of short-term cadmium-treated barley root tip
Keywords: LOX، لیپوکسیژناز; LOX, lipoxygenase; ROS, reactive oxygen speciesBarley; Cadmium; Cell death; Lipid peroxidation; Root growth inhibition; Root radial expansion
Inhibition of arachidonic acid metabolism by the Andean crude drug Parastrephia lucida (Meyen) Cabrera
Keywords: LOX، لیپوکسیژناز; AA, arachidonic acid; CAPE, caffeic acid phenethyl ester; COX, cyclooxygenase; 1,2dHGPC, 1,2-diheptanoilthio-glycerophosphocholine; DMSO, dimethyl sulfoxide; DTNB, 5,5′ dithiobis-2-nitrobenzoic acid; LTs, leukotrienes; LOX, lipoxygenase; NSAIDs, non-stero
Combined effects of 1-MCP and MAP on the fruit quality of pear (Pyrus bretschneideri Reld cv. Laiyang) during cold storage
Keywords: LOX، لیپوکسیژناز; MAP, modified atmosphere packaging; 1-MCP, 1-methylcyclopropene; SOD, super oxidase dismutase; POD, peroxidase; CAT, catalase; LOX, lipoxygenase; PAL, phenylalanine ammonialyase; PPO, polyphenol oxidase; MDA, malondialdehyde; SSC, soluble solids content;
Effect of endocannabinoids on soybean lipoxygenase-1 activity
Keywords: LOX، لیپوکسیژناز; 13-HpODE, 13(S)-hydroperoxyoctadecadienoic acid; 15(S)-HpETE, 15(S)-hydroperoxyeicosatatraenoic acid; Eox, active ferric enzyme form; Ered, inactive ferrous enzyme form; LOX, lipoxygenase; NA-DA, N-arachidonoyl dopamine; NA-Gly, N-arachidonoyl glycine; NA
Lipid metabolism is differentially modulated by salicylic acid and heptanoyl salicylic acid during the induction of resistance in wheat against powdery mildew
Keywords: LOX، لیپوکسیژناز; AGT, appressorial germ tube; Bgt, Blumeria graminis f. sp. tritici; BTH, benzothiadizole; Eth, ethanol; hai, hours after inoculation; hps, hours post treatment; HSA, heptanoyl salicylic acid; i, inoculated; LOX, lipoxygenase; ltp, lipid transfer protein;
Flavonoids as prospective compounds for anti-cancer therapy
Keywords: LOX، لیپوکسیژناز; TEAC, (Trolox)-equivalent antioxidant capacity assay; FRAP, Ferric Reducing Ability of Plasma assay; mTOR, mammalian target of rapamycin; COX, cyclooxygenase; LOX, lipoxygenase; GST, glutathione S-transferase; UDP-GT, uridine 5′-diphosphate-galactose; Mcl
A drought-sensitive barley variety displays oxidative stress and strongly increased contents in low-molecular weight antioxidant compounds during water deficit compared to a tolerant variety
Keywords: LOX، لیپوکسیژناز; ASC, ascorbic acid; CAT, catalase; DHA, dehydroascorbate; GSH, glutathione; LOX, lipoxygenase; MetO, methionine sulfoxide; MSR, methionine sulfoxide reductase; Prx, peroxiredoxin; ROS, reactive oxygen species; SOD, superoxide dismutase; Trx, thioredoxinAn
Lipidic last breath of life in patients with alcoholic liver disease
Keywords: LOX، لیپوکسیژناز; Alcoholic liver disease; Linoleic and arachidonic acid derivatives; HETE; HODE; Lipoxygenases (LOXs)ALD, alcoholic liver disease; FA, fatty acid; LOX, lipoxygenase; HODE, hydroxyoctadecadienoic acid; HETE, hydroxyeicosatetraenoic acid
Valuable chemicals by the enzymatic modification of molecules of natural origin: Terpenoids, steroids, phenolics and related compounds
Keywords: LOX، لیپوکسیژناز; API, active pharmaceutical ingredient; CaLB, Candida antartica lipase B; CPDMO, cyclopentadecanone monooxygenase; CPO, chloroperoxidase; CrL, Candida rugosa lipase; DMF, dimethylformamide; LOX, lipoxygenase; PLE, pig liver esterase; RTIL, room temperature
Role of leukotriene B4 receptor signaling in human preadipocyte differentiation
Keywords: LOX، لیپوکسیژناز; LT, leukotriene; LOX, lipoxygenase; TGFBI, transforming growth factor beta-induced 68 kDa; INS, insulin; DEX, dexamethasone; IBMX, 3-isobutyl-methylxanthine; ROSI, rosiglitazone; NDGA, nordehydroguaiaretic acid; TNFα, tumor necrosis factor alpha; IL-6, in
Global gene expression profiles in developing soybean seeds
Keywords: LOX، لیپوکسیژناز; Cluster dendrogram; DNA microarray; Seed development; Soybean; Storage proteinDEG, Differentially expressed genes; LOX, Lipoxygenase; 2D, Two-dimensional
Transcriptomic analysis of oxylipin biosynthesis genes and chemical profiling reveal an early induction of jasmonates in chickpea roots under drought stress
Keywords: LOX، لیپوکسیژناز; ABA; Drought stress; Jasmonate; Lipoxygenase; Oxylipins; Volatile aldehydesCH3CN, acetonitrile; LOX, lipoxygenase; HFA, hydro(pero)xy fatty acids; HPL, hydroperoxide lyase; PUFAs, polyunsaturated fatty acids; RP-HPLC, reverse-phase HPLC; SP-HPLC, straight
Antiplatelet effect of phloroglucinol is related to inhibition of cyclooxygenase, reactive oxygen species, ERK/p38 signaling and thromboxane A2 production
Keywords: LOX، لیپوکسیژناز; DCFH-DA, 2′,7′-dichlorodihydrofluorescein diacetate; AA, arachidonic acid; COX, cyclooxygenase; ERK, extracellular signal-regulated protein kinase; HBSS, Hanks balanced salt solution; LDH, lactate dehydrogenase; LOX, lipoxygenase; PMA, phorbol myristate a
The protective effect of nordihydroguaiaretic acid on cerebral ischemia/reperfusion injury is mediated by the JNK pathway
Keywords: LOX، لیپوکسیژناز; NDGA, nordihydroguaiaretic acid; LOX, lipoxygenase; I/R, ischemia/reperfusion; OGD, oxygen-glucose deprivation; HETE, hydroxyeicosatetraenoic acid; JNK, c-Jun N-terminal protein kinase; Aβ, amyloid β-peptide; AA, arachidonic acid; DMSO, dimethyl sulfoxide
Oligo-carrageenans induce a long-term and broad-range protection against pathogens in tobacco plants (var. Xanthi)
Keywords: LOX، لیپوکسیژناز; Oligo-carrageenans; Defense responses; Tobacco mosaic virus; Botrytis cinerea; Pectobacterium carotovorum; PAL; Nicotiana tabacumB. cinerea, Botrytis cinerea; P. carotovorum, Pectobacterium carotovorum; LOX, lipoxygenase; PAL, phenylalanine ammonia lyase;
Catalytic Activity and Acyl-Chain Selectivity of Diacylglycerol Kinase ɛ Are Modulated by Residues in and near the Lipoxygenase-Like Motif
Keywords: LOX، لیپوکسیژناز; DGK, diacylglycerol kinase; LOX, lipoxygenase; PI, phosphatidylinositol; PIP2, phosphatidylinositol-4,5-bisphosphate; SAG, 1-stearoyl-2-arachidonoyl-sn-glycerol; PA, phosphatidic acid; CRAC, cholesterol recognition/interaction amino acid consensus; SLG, 1
Functional characterization of SlscADH1, a fruit-ripening-associated short-chain alcohol dehydrogenase of tomato
Keywords: LOX، لیپوکسیژناز; ADH, alcohol dehydrogenase; LOX, lipoxygenase; MDR, medium-chain dehydrogenase/reductase; SDR, short-chain dehydrogenase/reductaseC5–C6 aroma volatiles; Fruit; Short-chain dehydrogenase-reductase; Solanum lycopersicum
Lipoxygenase in Caragana jubata responds to low temperature, abscisic acid, methyl jasmonate and salicylic acid
Keywords: LOX، لیپوکسیژناز; ABA, abscisic acid; DD, differential display of mRNA; JA, jasmonic acid; LOX, lipoxygenase; LT, low temperature; MJ, methyl jasmonate; ORF, open reading frame; RACE, rapid amplification of cDNA ends; SA, salicylic acid; SDS, sodium dodecyl sulfate; SMART,
Oxidation of glycerolipids by maize 9-lipoxygenase and its A562G mutant
Keywords: LOX، لیپوکسیژناز; CP-HPLC, chiral phase HPLC; LOX, lipoxygenase; lysoMGDG, 2-O-α-linolenoyl-3-O-β-d-galactopyranosyl-sn-glycerol; lysoPC, 1-linoleoyl-sn-glycero-3-phosphorylcholine; MGDG, 1,2-di-O-α-linolenoyl-3-O-β-d-sn-glycerol; MLG, 1-linolenoyl-rac-glycerol; NP-HPLC, n
Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways
Keywords: LOX، لیپوکسیژناز; AP, action potential; COX, cyclooxygenase; DRG, dorsal root ganglion; IB4, isolectin B4; LOX, lipoxygenase; PKA, protein kinase A; PKC, protein kinase C; PLA2, phospholipase A2; PLC, phospholipase C; TRPV1, transient receptor potential vanilloid receptor
Expression of defense genes and activities of antioxidant enzymes in rice resistance to rice stripe virus and small brown planthopper
Keywords: LOX، لیپوکسیژناز; Antioxidant response; Defense gene; Oryza sativa; Rice stripe virus; Small brown planthopperCAT, catalase; CHS, chalcone synthase; CP, coat protein; Gns, β-glucanase; H2O2, hydrogen peroxide; LOX, lipoxygenase; MDA, malondialdehyde; QTL, quantitative trai
Regulation of rat brain polyunsaturated fatty acid (PUFA) metabolism during graded dietary n-3 PUFA deprivation
Keywords: LOX، لیپوکسیژناز; AA, arachidonic acid; BDNF, brain derived neurotrophic factor; COX, cyclooxygenase; DHA, docosahexaenoic acid; DPAn-6, docosapentaenoic acid; LA, linoleic acid; α–LNA, α-linolenic acid; LOX, lipoxygenase; cPLA2, cytosolic phospholipase A2; sPLA2, secretor
The cellular redox state as a modulator in cadmium and copper responses in Arabidopsis thaliana seedlings
Keywords: LOX، لیپوکسیژناز; AsA, ascorbate; CAT, catalase; GR, glutathione reductase; GSH, glutathione; GSSG, glutathione disulfide; LOX, lipoxygenase; Px, peroxidase; ROS, reactive oxygen species; SOD, superoxide dismutaseArabidopsis thaliana; Cadmium; Copper; Cellular redox state;
A survey on basal resistance and riboflavin-induced defense responses of sugar beet against Rhizoctonia solani
Keywords: LOX، لیپوکسیژناز; AOPP, α-aminooxy-β-phenylpropionic acid; DI, disease index; dpi, days post inoculation; dpt, days post treatment; ET, ethylene; IR, induced resistance; ISR, induced systemic resistance; JA, jasmonic acid; LOX, lipoxygenase; PAL, phenylalanine ammonia-lyas