Keywords: LPA، اسید لیسوفسفیدید; ALT, alanine transaminase; i.p., intraperitoneal; LPA, lysophosphatidic acid; LPS, lipopolysaccharide; MPO, myeloperoxidase; TLR4, toll-like receptor 4; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling
مقالات ISI LPA، اسید لیسوفسفیدید (ترجمه نشده)
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Keywords: LPA، اسید لیسوفسفیدید; 18S, ribosomal protein S18; AA, aristolochic acid; α-SMA, α-smooth muscle actin; LC–MS/MS, liquid chromatography–tandem mass spectrometry; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; LPE, lyso
Distinct 1-monoacylglycerol and 2-monoacylglycerol kinase activities of diacylglycerol kinase isozymes
Keywords: LPA، اسید لیسوفسفیدید; AGK, acylglycerol kinase; DG, diacylglycerol; DGK, diacylglycerol kinase; LPA, lysophosphatidic acid; MG, monoacylglycerol; MGK, monoacylglycerol kinase; PA, phosphatidic acid; PS, phosphatidylserineDiacylglycerol kinase; Monoacylglycerol kinase; Lysophos
Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors
Keywords: LPA، اسید لیسوفسفیدید; C1P, ceramide 1-phosphate; CERA-1, ceramide analog-1; CERK, ceramide kinase; CRE, cAMP response element; LPA, lysophosphatidic acid; MCP-1, monocyte chemoattractant protein-1; PCERA-1, phospho-ceramide analog-1; SM, sphingomyelin; SMase, sphingomyelinase;
The total and mitochondrial lipidome of Artemia franciscana encysted embryos
Keywords: LPA، اسید لیسوفسفیدید; AC, acylcarnitine; CE, cholesteryl esters; Cer, ceramide; CL, cardiolipin; CoQ, coenzyme Q; DAG, diacylglycerol; PA, phosphatidic acid; LPA, lysophosphatidic acid; PC, phosphatidylcholine; LPC, lysophosphatidylcholine; PE, phosphatidylethanolamine; LEA, ‘
Agonists and protein kinase C-activation induce phosphorylation and internalization of FFA1 receptors
Keywords: LPA، اسید لیسوفسفیدید; FFAs, free fatty acids; DHA, docosahexaenoic acid; α-LA, α-linolenic acid; LPA, lysophosphatidic acid; PMA, phorbol 12-myristate, 13-acetate; PKC, protein kinase C; ERK 1/2, extracellular-signal-regulated kinases 1/2; GFP, green fluorescent protein; GPCRs
Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair/hypotrichosis: Establishment of a useful assay system for LPA6
Keywords: LPA، اسید لیسوفسفیدید; Woolly hair; Hypotrichosis; LPAR6; LPA6; LIPHWH, woolly hair; AD, autosomal dominant; AR, autosomal recessive; IRS, inner root sheath; HF, hair follicle; LPA, lysophosphatidic acid; GPCR, G protein–coupled receptor; PCR, polymerase chain reaction; RT, rev
Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels
Keywords: LPA، اسید لیسوفسفیدید; AGPAT, acylglycerophosphate acyltransferase; LPAAT, lysophosphatidic acid acyltransferase; PA, phosphatidic acid; LPA, lysophosphatidic acid; ALCAT, acyl-CoA:lysocardiolipin acyltransferase; LPEAT, lysophosphatidylethanolamine acyltransferase; LPCAT, lyso
Conventional protein kinase C isoforms mediate phorbol ester-induced lysophosphatidic acid LPA1 receptor phosphorylation
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; PKC, protein kinase C; PMA, phorbol myristate acetate; eGFP, enhanced green fluorescent protein; DN, dominant-negative; shRNA, short hairpin RNA; SDS-PAGE, sodium-dodecyl-sulfate poly-acrylamide gel electrophoresisLysophosphati
Lipoprotein-associated lysolipids are differentially involved in high-density lipoprotein- and its oxidized form-induced neurite remodeling in PC12 cells
Keywords: LPA، اسید لیسوفسفیدید; S1P, sphingosine 1-phosphate; LPA, lysophosphatidic acid; S1P1–5, S1P receptor type 1–5; LPA1–6, LPA receptor type 1–6; LPC, lysophosphatidylcholine; HDL, high-density lipoprotein; oxHDL, oxidized HDL; LDL, low-density lipoprotein; NGF, nerve growth facto
Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes
Keywords: LPA، اسید لیسوفسفیدید; ATX, autotaxin; CBP, CREB-binding protein; ERK, extracellular-signal regulated kinase; FLS, fibroblast-like synoviocytes; IL-8, interleukin-8; LPA, lysophosphatidic acid; LPA1, lysophosphatidic acid receptor 1; LPA3, lysophosphatidic acid receptor 3; MAPK
Functional lysophosphatidic acid receptors expressed in Oryzias latipes
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; RT-PCR, reverse transcription-polymerase chain reaction; cDNAs, complementary DNA; RACE, rapid amplification of cDNA ends; DMEM, Dulbecco's modified Eagle's medium; FCS, fetal calf serum; ANOVA, analysis of variance; AA, amino
Involvement of LPA1 receptor signaling in cerebral ischemia-induced neuropathic pain
Keywords: LPA، اسید لیسوفسفیدید; CPSP, central post-stroke pain; EPW, electrical stimulation-induced paw withdrawal; LPA, lysophosphatidic acid; LPA1−/−, LPA1 receptor knock-out mice; S.E.M., standard error of the mean; tMCAO, transient middle cerebral artery occlusion; TTC, 2,3,5-triphe
p190RhoGAP has cellular RacGAP activity regulated by a polybasic region
Keywords: LPA، اسید لیسوفسفیدید; GAP, GTPase activating protein; EGF, epidermal growth factor; LPA, lysophosphatidic acid; MEF, mouse embryonic fibroblast; PBR, polybasic region; PAK, p21-activated kinasep190RhoGAP; Rho; Rac; Polybasic region
Lysophosphatidic acid: A potential mediator of osteoblast–osteoclast signaling in bone
Keywords: LPA، اسید لیسوفسفیدید; BEL, bromoenol lactone; BzATP, 2′,3′-O-(4-benzoylbenzoyl)-ATP; [Ca2 +]i, cytosolic free calcium concentration; ERK, extracellular signal-regulated kinase; F-actin, filamentous actin; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; LPG, lysophosp
Eosinophil recruitment to nasal nerves after allergen challenge in allergic rhinitis
Keywords: LPA، اسید لیسوفسفیدید; AR, allergic rhinitis; CCL-26, chemokine (C-C motif) ligand 26; CCR-3, C-C chemokine receptor type 3; ChAT, choline acetyltransferase; ICAM-1, intercellular adhesion molecule 1; IgE, immunoglobulin E; IgG, immunoglobulin G; LPA, lysophosphatidic acid; MAP
Comparing the differential effects of LPA on the barrier function of human pulmonary endothelial cells
Keywords: LPA، اسید لیسوفسفیدید; HPAEC, human pulmonary artery endothelial cell; HMVEC, human microvascular endothelial cell; LPA, lysophosphatidic acid
New insights into the role of sphingosine 1-phosphate and lysophosphatidic acid in the regulation of skeletal muscle cell biology
Keywords: LPA، اسید لیسوفسفیدید; CTGF, connective tissue growth factor; DMS, dimethylsphingosine; ERK, extracellular signal-regulated kinase; IGF-1, insulin like growth factor-1; LPA, lysophosphatidic acid; PDGF, platelet-derived growth factor; PI3K, phosphatidylinositol 3-kinase; alphaS
Lysophosphatidic acid: Chemical signature of neuropathic pain
Keywords: LPA، اسید لیسوفسفیدید; ATX, autotaxin; CaM, calmodulin; CCR-2, chemokine (C-C motif) receptor-2; CIF, calcium influx factor; DRG, dorsal root ganglia; ER, endoplasmic reticulum; LPA, lysophosphatidic acid; LPC, lysophosphatidyl choline; MAG, myelin-associated glycoprotein; MALD
The actions and metabolism of lysophosphatidylinositol, an endogenous agonist for GPR55
Keywords: LPA، اسید لیسوفسفیدید; CoA, coenzyme A; DAG, diacylglycerol; FFA, free fatty acids; GP, glycerophosphate; GPI, glycerophosphoinositol; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; LPE, lysophosphatidylethanolamine; LPI, lysophosphatidylinositol; lysoPS, lysophospha
Enhancement of endothelial cell migration by constitutively active LPA1-expressing tumor cells
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; LPA1, LPA receptor-1; VEGF, vascular endothelial growth factor; RT, reverse transcription; PCR, polymerase chain reactionLPA receptor; Cell migration; VEGF; Endothelial cell; B103
Regulation of cell motile activity through the different induction of LPA receptors by estrogens in liver epithelial WB-F344 cells
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; LPA1, LPA receptor-1; E2, 17β-estradiol; EE, ethinyl estradiol; DES, diethylstilbestrol; RT, reverse transcription; PCR, polymerase chain reactionLPA; LPA receptor; Cell motility; Estrogen
ATX and LPA receptor 3 are coordinately up-regulated in lipopolysaccharide-stimulated THP-1 cells through PKR and SPK1-mediated pathways
Keywords: LPA، اسید لیسوفسفیدید; LPS, lipopolysaccharide; ATX, autotaxin; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; PKR, protein kinase regulated by RNA; JNK, c-Jun N-terminal kinase; ERK, extracellular signal-regulated kinase; SPK, sphingosine kinaseLysophosphatidic acid
Lysophospholipids and lysophospholipase D in rabbit aqueous humor following corneal injury
Keywords: LPA، اسید لیسوفسفیدید; AH, aqueous humor; ATX, autotoxin; BSA, bovine serum albumin; FBS, fetal bovine serum; GPC, glycerophosphocholine; KSFM, keratocyte serum free medium; LC–MS–MS, liquid chromatography–tandem mass spectrometry; LPA, lysophosphatidic acid; LPC, lysophosphati
Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; OSCC, oral squamous cell carcinoma; RANKL, receptor activator of nuclear factor (NF)-κB ligand; CM, conditioned medium; TRAP, tartrate-resistant acid phosphataseLysophosphatidic acid; IL-6; IL-8; Osteoclastogenesis; Oral squamo
Inhibition of Rho kinases increases directional motility of microvascular endothelial cells
Keywords: LPA، اسید لیسوفسفیدید; H1152, (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-homopiperazine; BrdU, 5-bromo-2′-deoxyuridine; CTGF, connective tissue growth factor; DMOG, dimethyl-oxalylglycine; HUVEC, human umbilical vein endothelial cell; LPA, lysophosphatidic acid; ML
Morphological phenotypes of olfactory ensheathing cells display different migratory responses upon Slit-2
Keywords: LPA، اسید لیسوفسفیدید; OECs, olfactory ensheathing cells; OE, olfactory epithelium; OB, olfactory bulb; FBS, fetal bovine serum; PLL, poly-L-lysine; LPA, lysophosphatidic acid; L15, Leibovitz's L-15 medium; Aniso, anisomycin; CHX, cycloheximide; CM, control medium; RoboN, mediu
Loss of lysophosphatidic acid receptor-3 enhances cell migration in rat lung tumor cells
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; Lpar3, LPA receptor-3; RT, reverse transcription; PCR, polymerase chain reaction; BHP, N-nitrosobis(2-hydroxypropyl)amineLpar3; Cell migration; Lung tumor; Rat
Quantitative determination of lysophosphatidic acids (LPAs) in human saliva and gingival crevicular fluid (GCF) by LC–MS/MS
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; GF, gingival fibroblasts; PDLF, periodontal ligament fibroblasts; GCF, gingival crevicular fluid; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MeOH, methanol; IS, internal standard; QC, quality controlLysophosphati
Phospholipase C-η1 is activated by intracellular Ca2+ mobilization and enhances GPCRs/PLC/Ca2+ signaling
Keywords: LPA، اسید لیسوفسفیدید; PLC, phospholipase C; DAG, diacylglycerol; IP3, inositol-1,4,5-triphosphates; GPCR, G protein-coupled receptor; N2A, neuro2A; shRNA, short-hairpin RNA; LPA, lysophosphatidic acid; PACAP, pituitary adenylate cyclase-activating polypeptide; ERK, extracellul
Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator
Keywords: LPA، اسید لیسوفسفیدید; BSA, bovine serum albumin; [Ca2+]i, intracellular free Ca2+ concentration; Cis-4M-S1P, cis-4-methylsphingosine-1-phosphate; Cis-4M-Sph, cis-4-methylsphingosine; LC–MS/MS, liquid chromatography–tandem mass spectrometry; LPA, lysophosphatidic acid; MEFs, mo
MAGI-3 Competes With NHERF-2 to Negatively Regulate LPA2 Receptor Signaling in Colon Cancer Cells
Keywords: LPA، اسید لیسوفسفیدید; G-Protein Signaling; Colorectal Cancer; Neoplasia; TumorigenesisGPCR, G-protein–coupled receptors; GTP, guanosine triphosphate; IκBα, inhibitory kappa Bα; JNK, c-Jun N-terminal kinase; LPA, lysophosphatidic acid; MAGI-3, membrane-associated guanylate kina
RhoA–ROCK–Myosin pathway regulates morphological plasticity of cultured olfactory ensheathing cells
Keywords: LPA، اسید لیسوفسفیدید; OECs, Olfactory ensheathing cells; FBS, fetal bovine serum; PLL, poly-L-lysine; LPA, lysophosphatidic acid; FRET, fluorescence resonance energy transfer; ROCK, Rho associated kinase; MLC, myosin light chainOlfactory ensheathing cells; RhoA; Morphological
Biochemical and Structural Characterization of Lysophosphatidic Acid Binding by a Humanized Monoclonal Antibody
Keywords: LPA، اسید لیسوفسفیدید; CDR, complementarity-determining region; cLPA, cyclic LPA; IgG, immunoglobulin G; LPA, lysophosphatidic acid; PEG, polyethylene glycol; PGE, triethylene glycol; S1P, sphingosine-1-phosphate; PBS, phosphate-buffered salineantibodies; cancer therapies; lipi
Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; RBC, red blood cell; S1P, sphingosine 1-phosphateCarbon tetrachloride; Chronic hepatitis C; Hyaluronic acid; Liver fibrosis; Sphingosine 1-phosphate
Regulation of ryanodine receptors by sphingosylphosphorylcholine: Involvement of both calmodulin-dependent and -independent mechanisms
Keywords: LPA، اسید لیسوفسفیدید; CaM, calmodulin; CMC, critical micelle concentration; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; RyR, ryanodine receptor; S1P, sphingosine-1-phosphate; SPC, sphingosylphosphorylcholine; SR, sarcoplasmic reticulumRyanodine receptor; Sphingos
Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway
Keywords: LPA، اسید لیسوفسفیدید; DIV, day in vitro; E, embryonic day; ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2; LPA, lysophosphatidic acid; MAPK, mitogen activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PLC, phospholipase C; ROCK, Rho-associated coiled-coil
Functional characterization of lysophosphatidic acid phosphatase from Arabidopsis thaliana
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; MAG, monoacylglycerol; PLA2, phospholipase A2; PLC, phospholipase C; TAG, triacylglycerolLysophosphatidic acid phosphatase; Lipid metabolism; Phylogenetic analysis; Soluble triacylglycerol biosynth
Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography–electrospray tandem mass spectrometry
Keywords: LPA، اسید لیسوفسفیدید; BSA, bovine serum albumin; FWHM, full-width at half-maximum; IS, internal standard; LLOQ, lower limit of quantification; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; QC, quality control; TEA, triethylamineLysophosphatidic acid (LPA); Lysophos
LPA3, a unique G protein-coupled receptor for lysophosphatidic acid
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; ATX, autotaxin; GPCR, G-protein-coupled receptor; LPP, lipid phosphate phosphatase; lysoPLD, lysophospholipase D; PAP, prostatic acid phosphatase; PLA, phospholipase A; PA, phosphatidic acidLPA3; Lysophosphatidic acid
IFN-λ endocytosis and IFN-λ responsive promoter activation are dependent on cholesterol
Keywords: LPA، اسید لیسوفسفیدید; CdTB, Clostridium difficile toxin B; GAS, γ-activated sequence; GPI, Glycosyl phosphatidylinositol; IFN-λ, interferon-lambda; ISRE, interferon stimulated response element; LAMP-1, lysosomal-associated membrane protein 1; LPA, lysophosphatidic acid; MβCD,
Distinct receptor-mediated activities in macrophages for natural ceramide-1-phosphate (C1P) and for phospho-ceramide analogue-1 (PCERA-1)
Keywords: LPA، اسید لیسوفسفیدید; PCERA-1, phospho-ceramide analogue-1; CERA-1, ceramide analog-1; TLR, toll like receptor; LPS, lipopolysaccharide; TNFα, tumor necrosis factor alpha; IL-10, interleukin-10; S1P, sphingosine-1-phosphate; LPA, lysophosphatidic acid; C1P, ceramide-1-phosphat
Identification of a novel splicing isoform of murine CGI-58
Keywords: LPA، اسید لیسوفسفیدید; CGI-58, comparative gene identification-58; CDS, Chanarin-Dorfman syndrome; LPA, lysophosphatidic acid; PA, phosphatidic acid; ATGL, adipose triglyceride lipase; TAG, triacylglycerolNeutral lipid storage disease; Lipolysis; Triacylglycerol; Lipid droplet;
Mesenchymal stem cells stimulate angiogenesis in a murine xenograft model of A549 human adenocarcinoma through an LPA1 receptor-dependent mechanism
Keywords: LPA، اسید لیسوفسفیدید; CAFs, carcinoma-associated fibroblasts; α-SMA, α-smooth muscle actin; MSCs, mesenchymal stem cells; LPA, lysophosphatidic acid; hASCs, human adipose tissue-derived mesenchymal stem cells; GAPDH, glyceraldehydes-3-phosphate dehydrogenase; DAPI, 4',6-diamid
Generation of lysophosphatidylinositol by DDHD domain containing 1 (DDHD1): Possible involvement of phospholipase D/phosphatidic acid in the activation of DDHD1
Keywords: LPA، اسید لیسوفسفیدید; FFA, free fatty acid; GPCR, G-protein-coupled receptor; LPA, lysophosphatidic acid; LPI, lysophosphatidylinositol; MAFP, methyl arachidonoyl fluorophosphate; PA, phosphatidic acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PI, phosphatidylino
Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells
Keywords: LPA، اسید لیسوفسفیدید; ccPA, 2-carbocyclic phosphatidic acid; FCS, fetal calf serum; LPA, lysophosphatidic acid; S1P, sphingosine 1-phosphate; SRB, sulforhodamine BAutotaxin; Ovarian; Drug resistance; RNAi; Carboplatin
Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+/H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2
Keywords: LPA، اسید لیسوفسفیدید; Apc, adenomatous polypopsis coli; BSA, bovine serum albumin; CT, cholera toxin; CFTR, cystic fibrosis transmembrane conductance regulator; LPA, lysophosphatidic acid; mRNA, messenger RNA; NHE3, Na+/H+ exchanger type 3; NHERF, Na+/H+ exchanger regulatory f
Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair
Keywords: LPA، اسید لیسوفسفیدید; hypotrichosis simplex; lipase H gene; mutation; woolly hairHT, hypotrichosis; LIPH, lipase H gene; PCR, polymerase chain reaction; LPA, lysophosphatidic acid
Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway
Keywords: LPA، اسید لیسوفسفیدید; LPA, lysophosphatidic acid; ES cells, embryonic stem cells; ICM, inner cell mass; PLC, phospholipase C; SERCA, Sarcoplasmic/endoplasmic reticulum (ER) Ca2+-ATPaseEmbryonic stem cells; Lysophosphatidic acid; Ca2+; Phospholipase C; c-Myc
Lysophospholipids enhance taurine release from rat retinal vascular endothelial cells under hypoosmotic stress
Keywords: LPA، اسید لیسوفسفیدید; BRB, blood-retinal barrier; DMEM, Dulbecco's modified Eagle's medium; LPA, lysophosphatidic acid; PKC, protein kinase C; RVEC, retinal vascular endothelial cell; S1P, sphingosine 1-phosphate; VSOAC, volume-sensitive organic osmolyte and anion channelInner