Keywords: Lipid mediators; Fatty acid/oxidation; Method development; Polyunsaturated fatty acids; Free fatty acids; Stable isotope dilution analysis; BHT; 3,5-di-tert-4-butylhydroxytoluene; CXP; cell exit potential; CV; coefficient variation; CE; collision
مقالات ISI (ترجمه نشده)
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Keywords: RA; rheumatoid arthritis; RF; rheumatoid factor; ACPA; anti-citrullinated protein antibodies; AA; arachidonic acid; PG; prostaglandins; LT; leukotrienes; TX; thromboxanes; LX; lipoxins; NSAID; non steroidal anti-inflammatory drugs; COXIB; COX-2 selective
Keywords: Cisplatin; Zileuton; 5-LOX; LTD4; LTB4;
Keywords: 15-PGDH; 15-hydoxyprostaglandin dehydrogenase; AA; arachidonic acid; AF; atrial fibrillation; AKI; acute kidney injury; Akt; alpha serine/threonine-protein kinase; ALA; alpha-linolenic acid; AMD; age-related macular degeneration; Ang II; angiotensin II; B
Keywords: RPKM; reads per kilobase of transcript per million mapped reads; FGF; fibroblast growth factor; ETS; E26 transformation-specific or E-twenty-six; LTs; leukotrienes; ALOX5; arachidonate 5-lipoxygenase; LTA4; leukotriene A4; LTB4; leukotriene B4; LTC4; leuk
Keywords: Tfh cells; T follicular helper cells; LXA4; lipoxin A4; LTB4; leukotriene B4; FPR2; formyl peptide receptor 2; Lipid mediators; T follicular helper cells;
Keywords: ADFI; average daily feed intake; ADG; average daily gain; ANOVA; analysis of variance; BW; body weight; COX-2; cyclooxygenase-2; CP; crude protein; D; dietary treatments; DE; digestible energy; DHA; docosahexaenoic acid; DM; dry matter; E; environmental c
Keywords: Mast cells; Leukotriene receptors; cysLTs; LTB4; Inflammation;
Keywords: SPM; specialised pro-resolving mediators; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; 18-HEPE; 18-hydroxyeicosapentaenoic acid; 10Â S; 17S-DiHDoHE, 10Â S,17S-dihydroxydocosahexaenoic acid; 14-HpDHA; 14-hydroperoxydocosahexaenoic acid; 14-HDHA;
Keywords: AA; arachidonic acid; COX; cyclooxygenase; d; deuterated; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HDHA; hydroxy-docosahexaenoic acid; HEPE; hydroxy-eicosapentaenoic acid; HETE; hydroxy-eicosatetraenoic acid; HpETE; hydroperoxy-eicosatetraen
Keywords: AGEs; advanced glycation end products; ATM; Adipose tissue macrophage; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor 1; CXCL; CXC chemokine l
Keywords: CF; cystic fibrosis; PMN; polymorphonuclear neutrophil; IL-8; interleukin-8; LTB4; leukotriene B4; HDI; high-dose ibuprofen; IL-6; interleukin-6; IL-1β; interleukin-1beta; TNF-α; tumor necrosis factor-alpha; FEV1; forced expiratory volume in 1 s; NSAID
Keywords: ACTH; adrenocorticotropin; α-MSH; alpha melanocyte stimulating hormone; HBSS; Hank's buffered saline solution; LTB4; leukotriene B4; PAF; platelet activating factor; POMC; proopiomelanocortin; PPID; pituitary pars intermedia dysfunction; PPID; Alpha-mela
Keywords: Allergic diseases; CysLTs; Leukotrienes; Lipid mediators; LTB4
Keywords: BoE; biomarker of exposure; BoBE; biomarker of biological effect; BoED; biomarker of effective dose; FDA; Food and Drug Administration; IOM; Institute of Medicine; ISO; International Organisation for Standardisation; ISRCTN; International Standard Randomi
Keywords: Mast cells; Recruitment; IL-3; SCF; RANTES; LTB4; In vivo;
Keywords: Eicosanoids; Prostaglandins; Leukotrienes; PGE2; LTB4; Liquid chromatography–tandem mass spectrometry; Human plasma
Keywords: CI; combination index; ED50; 50% effective dose; ELISA; enzyme linked immunosorbent assay; HMGB1; high mobility group box 1; IFN-γ; interferon-gamma; IL; interleukin; LTB4; leukotrienes B4; LPS; lipopolysaccharide; MLA; methyllycaconitine; PGE2; prostagl
Keywords: Diethylnitrosamine; Alkenal/one oxidoreductase; Carcinogen detoxification enzymes; 4-Hidroxynonenal; Tumor marker; HCC; hepatocellular carcinoma; DEN; diethylnitrosamine; S&F; Solt and Farber model; LTB4; leukotriene B4; PGE2; prostaglandin E2; 15d-PGJ2;
Keywords: Mouse paw edema; Chemotaxis; Inhibition of apoptosis; Pro-inflammatory eicosanoids; Reactive oxygen species; Urease inhibitor; rHPU; recombinant Helicobacter pylori urease; LTB4; leukotriene B4; ROS; reactive oxygen species; PMA; phorbol 12-myristate 13-a
Keywords: AA; arachidonic acid; AD; Alzheimer's disease; ANOVA; analysis of variance; DA; dopamine; DAB; 3,3â²-diaminobenzidine; DOPAC; dihydroxyphenylacetic acid; EDTA; ethylenediaminetetraacetic acid; GFAP; glial acidic fibrillary protein; HETE; hydroxyeicosat
Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
Leptin in autoimmune mechanisms of systemic rheumatic diseases
Keywords: Leptin; Connective tissue diseases; Adipokines; Inflammatory arthritis; Vasculitis; WAT; white adipose tissue; IL; interleukin; BMI; body mass index; PPAR; peroxisome proliferator-activated receptor; JAK; janus kinases; STAT; signal transducers and activa
Multiple mechanisms underlying neuroprotection by secretory phospholipase A2 preconditioning in a surgically induced brain injury rat model
Keywords: SBI; surgical brain injury; PLA2; phospholipase A2; PPC; PLA2 preconditioning; 5-LOX; 5-lipoxygenase; AA; arachidonic acid; LTB4; leukotriene-B4; BWC; brain water content; WBC; white blood cells; GFAP; glial fibrillary acidic protein; MPO; myeloperoxidase
Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis
Keywords: atherosclerosis; burden; imaging; inflammation; permeability; 18F-FDG; 18F-fluorodeoxyglucose; 3D; 3-dimensional; 5LO; 5-lypoxigenase; AUC; area under the curve; CT; computed tomography; DCE; dynamic contrast-enhanced; FLAP; 5-LO-activating protein; HFD;
Prostaglandin E2 as a Regulator of Immunity to Pathogens
Keywords: AA; Arachidonic Acid; BMT; Bone marrow transplant; cAMP; Cyclic adenosine monophosphate; COX; Cyclooxygenase; EP; E-type prostanoid; EPAC; Exchange protein directly activated by cAMP; ERK; Extracellular signal-regulated kinases; GSK-3; Glycogen synthase k
Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A review
Keywords: NCBI; National Centre for Biotechnology Information; SARS; Severe acute respiratory syndrome; NO; Nitric Oxide; LPS; Lipopolysaccharide; NF-κB; Nuclear factor kappa B; ROS; Reactive Oxygen Species; TNF-α; Tumor Necrosis Factor-α; IL; Interleukin; MCP-1
Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity
Keywords: CFA; complete Freund's adjuvant; CB; cytochalasin B; fMLF; N-formyl-Met-Leu-Phe; HE; hydroethidine; LPS; lipopolysaccharide; LTB4; leukotriene B4; MMK-1; Leu-Glu-Ser-Ile-Phe-Arg-Ser-Leu-Leu-Phe-Arg-Val-Met; MAPK; mitogen-activated protein kinase; MPO; m
The chemistry and pharmacology of Ligularia przewalskii: A review
Keywords: A375; human melanoma cells; ABTS; 2,2'-azinobis (3-ethylbenzothiazoline-6- sulfonic acid); AChE; acetylcholinesterase; AD; Alzheimer's disease; AGEs; advanced glycation endproducts; B16F10; mouse skin melanoma; BACE1; β-site amyloid precursor cleavin
Identification, signaling, and functions of LTB4 receptors
Keywords: AA; arachidonic acid; CLDN4; claudin-4; COX; cyclooxygenase; DGS3; desmoglein-3; DSS; dextran sodium sulfate; 5-LOX; 5-lipoxygenase; 5(S)-HETE; 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5(S)-HpETE; 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic a
Importance of the leukotriene B4-BLT1 and LTB4-BLT2 pathways in asthma
Keywords: BLT1; LTB4; Asthma; CD4 T lymphocytes; CD8 T lymphocytes;
Recent advances in clinical development of leukotriene B4 pathway drugs
Keywords: Leukotriene; LTB4; BLT1; LTA4 hydrolase; Drug development; Clinical study;
Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1
Keywords: [Ca2+]i; intracellular calcium concentration; ALI; acute lung injury; CB; cytochalasin B; CsH; cyclosporine H; FBS; fetal bovine serum; FNLFNYK; N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys-fluorescein; FPR1; formyl peptide receptor 1; HE; Hydroethidine; H89; N-[2-(p
Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of “sensors” of foreign and endogenous signals
Keywords: AA; arachidonic acid; AHH; aryl hydrocarbon hydoxylase; AHR; aryl hydrocarbon receptor; ARNT; aryl hydrocarbon receptor translocator; B6; C57BL/6J mice; bHLH; basic-helix/loop/helix domain in proteins; Chr; chromosome; CNS; central nervous system; CYP; cy
The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa Acquisita
Keywords: C7; type VII collagen; GST-C7; GST fusion protein containing a fragment of the immunodominant NC1 domain of murine C7; His-C7; His-tagged fragment of the immunodominant NC1 domain of murine C7; HSA; human serum albumin; KO; knockout; LTB4; leukotriene B4;
The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita
Keywords: 5-LO; 5-lipoxygenase; BP; bullous pemphigoid; EBA; epidermolysis bullous acquisita; LTB4; leukotriene B4; ROS; reactive oxygen species;
Obesity is positively associated with arachidonic acid-derived 5- and 11-hydroxyeicosatetraenoic acid (HETE)
Keywords: AEA; arachidonoyl ethanolamide; AG; arachidonoyl glycerol; ALA; alpha-linolenic acid; ARA; arachidonic acid; BHT; butylated hydroxytoluene; BMI; body mass index; COX; cyclooxygenase; CYP; cytochrome P450 enzymes; DGLA; dihomo-gamma-linolenic acid; DHA; do
Lipidomics in translational research and the clinical significance of lipid-based biomarkers
Keywords: 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise
Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X
Keywords: ALDH; aldehyde dehydrogenase; COX-2; cyclooxygenase-2; DHA; docosahexaenoic acid; DNA; deoxyribonucleic acid; EPA; eicosapentaenoic acid; ESI; electrospray ionization; GroPCho; glycerophosphocholine; GSH; glutathione; HDL; high density lipoprotein; HNE; 4
Inhibition of 5-lipoxygenase suppresses vascular endothelial growth factor-induced angiogenesis in endothelial cells
Keywords: 5-Lipoxygenase; Anti-angiogenic effects; Vascular endothelial growth factor signaling; CAM; chorioallantoic membrane; FBS; fetal bovine serum; HUVEC; human umbilical vein endothelial cell; VEGF; vascular endothelial cell growth factor; 5-LOX; 5-lipoxygena
Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation
Keywords: 4-MDM; 4-methoxydiphenylmethane; ACN; acetonitrile; APPI; atmospheric pressure photoionization; BCS; biopharmaceutical classification system; CAD; collision activated dissociation; CE; collision energy; COPD; chronic obstructive pulmonary disease; CEP; co
Neutrophil swarming toward Cryptococcus neoformans is mediated by complement and leukotriene B4
Keywords: Neutrophils; Cryptococcus neoformans; Swarming; Complement; CD11b; LTB4; C3; complement component 3; C5; complement component 5; C5a; complement component 5a; C5aR; complement component 5a receptor; CXCL1; chemokine (C-X-C motif) ligand 1; CXCL2; chemokin
β-naphthoflavone interferes with cyp1c1, cox2 and IL-8 gene transcription and leukotriene B4 secretion in Atlantic cod (Gadus morhua) head kidney cells during inflammation
Keywords: β -naphthoflavone; Cod head kidney cells; LPS; cyp1c1; cox2,IL-8; LTB4
Efficacy and safety of Derris scandens (Roxb.) Benth. for musculoskeletal pain treatment: A systematic review and meta-analysis of randomized controlled trials
Keywords: NLEMs; National List of Essential Medicines; NSAIDs; Nonsteroidal anti-inflammatory drugs (NSAIDs); COX-1; Cyclooxygenase 1; LTB4; Leukotriene-B4; AEs; Adverse events; RCT; Randomized controlled trial; PRISMA; Preferred Reporting Items for Systematic Revi
Sickle red cells as danger signals on proinflammatory gene expression, leukotriene B4 and interleukin-1 beta production in peripheral blood mononuclear cell
Keywords: AA-PBMC; peripheral blood mononuclear cells freshly isolated from healthy individuals; AA-RBC; red blood cell from healthy individuals; ASC; apoptosis-associated speck-Like protein containing card; DAMPs; damage-associated molecular pattern molecules (DAM
Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation
Keywords: LTB4; BLT2; Vimentin; EMT; Comp A; ERK2;
Intestinal anti-inflammatory activity of calcium pyruvate in the TNBS model of rat colitis: Comparison with ethyl pyruvate
Keywords: CPM; calcium pyruvate monohydrate; EP; ethyl pyruvate; GSH; glutathione; IBD; inflammatory bowel disease; ICAM-1; intercellular adhesion molecule-1; IFNγ; interferon γ; IL; interleukin; iNOS; inducible nitric oxide synthase; LTB4; leukotriene B4; MCP-1;
Molecular mechanisms of LL-37-induced receptor activation: An overview
Keywords: AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;
Thermodynamic properties of leukotriene A4 hydrolase inhibitors
Keywords: LTA4H; leukotriene A4 hydrolase; LTA4; leukotriene A4; LTB4; leukotriene B4; kDa; kilo Dalton; PGP; prolin-glycin-prolin; TSA; thermal shift assay; TM; melting point; ITC; isothermal titration calorimetry; DSF; different scanning fluorimetry; Ki; inhi
Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions
Keywords: DHET; dihydroxy-eicosatrienoic acid; HETE; hydroxy-eicosatetraenoic acid; LTB4; leukotriene B4; EpOME; epoxy-octadecenoic acid; EET; epoxy-eicosatrienoic acid; TXB2; thromboxane B2; PGD2; prostaglandin D2; HODE; hydroxy-octadecadienoic acid; DiHOME; dihyd