Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis)
Keywords: MAVS; Tree shrew; Antiviral innate immunity; Evolutionary conservation
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Conserved inhibitory role of teleost SOCS-1s in IFN signaling pathways
Keywords: SOCS-1; suppressor of cytokine signaling 1; CISH; cytokine-inducible SH2-domain containing protein; IFN; interferon; MAVS; mitochondrial antiviral signaling protein; JAK-STAT; the Janus kinase signal transducer and activator of transcription; ISG; IFN-sti
Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens
Keywords: MAVS; mitochondrial antiviral signaling gene; IFN; type I interferon; SNPs; single nucleotide polymorphisms; CDS; coding region; UTR; untranslated region; PRRs; pathogen recognition receptors; PAMPs; pathogen-associated molecular patterns; TLRs; toll-like
ReDuNing, a patented Chinese medicine, reduces the susceptibility to H1N1 influenza of mice loaded with restraint stress
Keywords: Influenza virus; Restraint stress; Pneumonia; ReDuNing; RDN; ReDuNing; TCM; traditional Chinese medicines; NP; nucleoprotein; NF-κB; nuclear factor-kappa B; IL-1β; interleukin-1β; IFITM3; interferon inducible transmembrane 3; MAVS; mitochondrial antivi
Fish MAVS is involved in RLR pathway-mediated IFN response
Keywords: Crucian carp Carassius auratus; MAVS; MITA; RLR signaling pathway; IFN response
Human pegivirus (GB virus C) NS3 protease activity inhibits induction of the type I interferon response and is not inhibited by HCV NS3 protease inhibitors
Keywords: Human pegivirus; GB Virus-C; Hepatitis C virus; MAVS; TRIF; Type I interferon; Serine protease; Protease inhibitors;
How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1
Keywords: AIM 2; absent in melanoma 2; ASC; apoptosis-associated speck-like protein containing a caspase activation and recruitment domain; CAPS; cryopyrin-associated periodic syndromes; CARD; Caspase Activation and Recruitment Domain; Casp1; Caspase-1; DAMP; dange
Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection
Keywords: BiFC; bimolecular fluorescence complementation; CARD; caspase activation and recruitment domain; cGAMP; cyclic GMP-AMP; cGAS; cyclic GMP-AMP synthase; DC; dendritic cell; DUB; deubiquitinase; hSTING; human STING; IFN; interferon; IRF-3; interferon regulat
The intricate interplay between RNA viruses and NF-κB
Keywords: ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;
MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells
Keywords: BM; bone marrow; MAVS; mitochondrial antiviral signaling protein; MDA5; melanoma differentiation associated gene 5; MV; measles virus; RIG-I; retinoic acid inducible gene-I; TICAM1; Toll/IL-1 receptor homology domain-containing adaptor molecule 1; WT; wil
Journal of Hepatology Update: Hepatitis CInnate and adaptive immune responses in HCV infections
Keywords: AHC; acute hepatitis C; CHC; chronic hepatitis C; HCV; hepatitis C virus; IFN; interferon; IRF; interferon regulatory factor; ISG; interferon-stimulated gene; MAVS; mitochondrial anti-viral signalling protein; Mda5; melanoma differentiation antigen 5; NK
UXT plays dual opposing roles on SARM-induced apoptosis
Keywords: LPS; lipopolysaccharide; SARM; sterile α and heat armadillo motif-containing protein; UXT; ubiquitously expressed transcript; TLR; toll-like receptor; MAVS; mitochondrial anti-viral signaling protein; TIR; toll/interleukin-1 receptor; TNF; tumor necrosis
Research ArticleIndependent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes
Keywords: HCV; hepatitis C virus; IFN; interferon; NK; natural killer; PAMP; pathogen associated molecular pattern; PRR; pattern recognition receptor; TLR3; Toll-like receptor 3; RIG-I; retinoic acid inducible gene I; MAVS; mitochondrial antiviral-signaling protein
A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane using bioluminescence resonance energy transfer
Keywords: BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; CARD; caspase activation and recruitment domain; HCV; hepatitis C virus; HEK; human embryonic kidney; HR1; 4,3 hydrophobic heptad repeat region 1; IFN-β; int
ReviewInnate immunity and HCV
Keywords: AHC; acute hepatitis C; CHC; chronic hepatitis C; DC; dendritic cell; HCV; hepatitis C virus; IFN; interferon; IFNAR; IFN-α receptor; IFNGR; IFN-γ receptor; IRF; interferon regulatory factor; ISG; interferon-stimulated gene; MAVS; mitochondrial antivira
DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication
Keywords: 5â² ppp; 5â² triphosphate; AIM2; Absent In Melanoma 2; ARE; AU-rich element; CARD; Caspase Activation and Recruitment Domains; CDN; cyclic dinucleotide; cGAMP; cyclic-GMP-AMP; cGAS; cGAMP Synthase; CRM1; Chromosome Maintenance Region 1; CstF; Cleavage S
Mitochondrial anti-viral immunity
Keywords: Mitochondria; Anti-viral immunity; RIG-I like receptors; MAVS; Ubiquitin
Translocase of outer mitochondrial membrane 70 induces interferon response and is impaired by hepatitis C virus NS3
Keywords: HCV; Tom70; MAVS; IFN; IRF-3; NS3;
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and
Interferon-γ-Stimulated Genes, but Not USP18, Are Expressed in Livers of Patients With Acute Hepatitis C
Keywords: HCV; Jak-STAT Signaling; Host-Virus Interaction; Immune Response; AHC; acute hepatitis C; CHC; chronic hepatitis C; CHC-NR; CHC nonresponder; CHC-R; CHC responder; HCV; hepatitis C virus; HPF; high-power field; ISG; interferon-stimulated gene; JAK; Ja
Expression profiles of carp IRF-3/-7 correlate with the up-regulation of RIG-I/MAVS/TRAF3/TBK1, four pivotal molecules in RIG-I signaling pathway
Keywords: RIG-I; MAVS; TRAF3; TBK1; Common carp
Differential, Type I Interferon-Mediated Autophagic Trafficking of Hepatitis C Virus Proteins in Mouse Liver
Keywords: Autophagy; TLR3; Liver Disease; RIG-I; AdLacZ; recombinant adenovirus LacZ; ER; endoplasmic reticulum; HCV; hepatitis C virus; IFN; interferon; IRF-3; IFN regulatory factor-3; ISG; IFN-stimulated gene; LAMP1; lysosome-associated membrane protein 1; LC3B;
The role of mitochondria in the mammalian antiviral defense system
Keywords: MAVS; Innate immunity; NLRX1; STING; Mitochondria; Apoptosis
Degradation of RIG-I following cytomegalovirus infection is independent of apoptosis
Keywords: RIG-I; MAVS; IPS-1; Cardif; vMIA; UL37x1; Cleavage; Apoptosis; Cytomegalovirus
Mitochondrial factors in the regulation of innate immunity
Keywords: MAVS; IPS-1; Cardif; VISA; Mitochondria; Innate Immunity; CARD domain
RIG-I-like receptors: Sensing and responding to RNA virus infection
Keywords: RIG-I; MDA-5; MAVS; STING; RNA virus
The role of mitochondria in cellular defense against microbial infection
Keywords: Mitochondria; Innate immunity; Viruses; Bacteria; Microbial pathogenesis; RIG-I; MAVS; NLRX1
GuÃa de práctica clÃnica para la valoración del riesgo cardiaco preoperatorio y el manejo cardiaco perioperatorio en la cirugÃa no cardiaca1
Keywords: AAA; aneurisma aórtico abdominal; ACC; American College of Cardiology; AHA; American Heart Association; BNP; péptido natriurético cerebral; BRA; bloqueador de los receptores de la angiotensina; CABG; cirugÃa de bypass aortocoronario; CASS; Coronary Ar
The mitochondrial antiviral signaling protein, MAVS, is cleaved during apoptosis
Keywords: MAVS; IPS-1; Cardif; Apoptosis; Innate immunity; Mitochondria; Cleavage; Proteasome; Caspase
Potential Relevance of Cytoplasmic Viral Sensors and Related Regulators Involving Innate Immunity in Antiviral Response
Keywords: CARD; Caspase-recruiting domain; Cardif; caspase-recruiting domain adaptor inducing IFN-β; G3PDH; glyceraldehyde-3-phosphate dehydrogenase; HCV; hepatitis C virus; IPS-1; IFN-β promoter stimulator I; ISG15; IFN-stimulated gene 15; PEG-IFN; pegylated int
Antiviral Suppression vs Restoration of RIG-I Signaling by Hepatitis C Protease and Polymerase Inhibitors
Keywords: EC50; 50% effective concentration; HCV; hepatitis C virus; IFN; interferon; IRF-3; IFN regulatory factor 3; ISG; IFN-stimulated gene; MAVS; mitochondrial antiviral signaling protein (also, IPS-1, Cardif, VISA); NS; nonstructural protein; RIG-I; retinoic a
Angioma cavernoso del segundo nervio craneal y apoplejÃa quiasmática
Keywords: Angioma cavernoso; ApoplejÃa quiasmática; Nervio óptico; Cavernous angioma; Chiasmatic apoplexy; Optic nerve; AC; angioma cavernoso; ACs; angiomas cavernosos; IRM; imagen por resonancia magnética; SNC; sistema nervioso central; MAV; malformación arte
Innate immune evasion by hepatitis C virus and West Nile virus
Keywords: LGP2; IPS-1; IRF-3; MAVS; RIG-I; Interferon; JAK; STAT