Keywords: UVB; UVA; Melanoma; MC1R; NER; Immunosuppression;
مقالات ISI (ترجمه نشده)
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Keywords: ASIP; Agouti signalling protein; BMDC; bone marrow-derived cell; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptor; HBD3; human β-defensin 3; KITLG; KIT ligand; LN; lymph node; MC; melanoma cell; MC1R; melanocortin 1 receptor;
Keywords: ACTH; adrenocorticotrophic hormone; α-MSH; alpha-melanocyte stimulating hormone; b-FGF; basic fibroblast growth factor; CREB; cAMP response element binding protein; DDB; deep dermal burns; DCT; dopachrome tautomerase; Ednr; endothelin receptor; e-McSCs;
Keywords: α-Msh; Asip; Fish; Mc1r; Pigmentation; Pomc;
Keywords: Melanoma; Non-melanoma skin cancer; Risk factors; MC1R; Second malignancy; Keratinocyte skin cancer;
Keywords: Ab; antibody; ACP; alternating current polarography; APBA; 4-(2-(4-acetylthio)phenyl)ethynyl)benzoic acid; APTA; ptamer; AuE; gold electrode; AuSPE; gold screen printed electrode; BDDE; boron doped diamond electrode; BR; Britton-Robinson; CNT; carbon nano
Keywords: Melanoma; MC1R; Tumour infiltrating lymphocytes; Cytotoxic T lymphocytes; Immunotherapy
Keywords: Melanin; Eumelanin; Ultraviolet radiation; MC1R; Afro-textured hair; Thermoregulation; African American;
Keywords: CSLM; confocal scanning laser microscopy; MC1R; melanocortin-1 receptor; PD; Parkinson disease; SEER; Surveillance Epidemiology and End Results; SES; socioeconomic status;
Keywords: anesthesia – genetics; pharmacogenetics; drug–drug interactions; drug–gene interactions; CYP2D6; CYP3A4; CYP2B6; opioid metabolism; OPRM1; OPRK1; UGT2B7; COMT; GABA; ABCB1; MC1R
Keywords: MC1R; Selection; Animal breeding;
Keywords: Ovis aries; Animal genetic resources; Coat color pigmentation; GWAS; MC1R; Molecular markers
Association of the 16q24.3 region gene variants rs1805007 and rs4785763 with heightened risk of melanoma in Latvian population
Keywords: ACD; adrenocortical dysplasia protein homolog gene; AFG3L1P; AFG3-like matrix AAA peptidase subunit 1 of the pseudogene; BAP1; BRCA1 associated protein-1 gene; BRAF; serine/threonine-protein kinase B-Raf; CDK4; cyclin-dependent kinase 4; CDK10; cyclin-dep
Mc1r gene in Astroblepus pholeter and Astyanax mexicanus: Convergent regressive evolution of pigmentation across cavefish species
Keywords: Astroblepus pholeter; Chaetostoma microps; Astyanax; Cave; Catfish; Jumandi cave; Troglobite; Reduction in pigmentation; Regressive evolution; OCA2; Mc1r;
Dynamic regulation of mRNA and miRNA associated with the developmental stages of skin pigmentation in Japanese ornamental carp
Keywords: DEGs; differentially expressed genes; DEMs; differentially expressed miRNAs; dph; days post hatching; mc1r; melanocortin 1 receptor; mitf; microphthalmia-associated transcription factor; tyr; tyrosinase; tyrp1; tyrosinase related protein 1; dct; dopachrom
Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase
Keywords: ARRB; β-arrestin; β2AR; β2-adrenergic receptor; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; LOF; loss-of-function; αMSH; α melanocyte-stimulating hormone; MCR; melanocortin receptor; MC1R; melanocortin 1 receptor; MGRN1;
Left-right pigmentation pattern of Japanese flounder corresponds to expression levels of melanocortin receptors (MC1R and MC5R), but not to agouti signaling protein 1 (ASIP1) expression
Keywords: α-MSH; alpha-melanophore-stimulating hormone; MCH; melanin-concentrating hormone; ASIP1; agouti-signaling protein; MC1R; melanocortin 1 receptor; MC5R; melanocortin 5 receptor; MCHR2; melanin-concentrating hormone receptor 2; Asymmetrical coloration; Cou
Key amino acid residue in Melanocortin-1 receptor (melanocyte α-MSH receptor) for ligand selectivity
Keywords: POMC; MC1R; Melanocortins; Agonist; α-MSH;
Association of five SNPs with human hair colour in the Polish population
Keywords: Hair pigmentation; SNP; MC1R; OCA2; HERC2; SLC24A5; SLC45A2; TPCN2; TYR; TYRP1;
ReviewRecent development of signaling pathways inhibitors of melanogenesis
Keywords: UVR; ultraviolet radiation; CNS; central nervous system; TYR; tyrosinase; TRP-1; tyrosinase-related protein-1; TRP-2; tyrosinase-related protein-2; DQ; dopaquinone; DCT; dopachrome tautomerase; α-MSH; α-melanocyte stimulating hormone; MC1R; melanocortin
Nanomedicine as a potent strategy in melanoma tumor microenvironment
Keywords: α-SMA; α-smooth muscle actin; MCP1; monocyte chemotactic protein 1; FAP; fibroblast activation protein; PDGF; platelet-derived growth factor; HGF; hepatocyte growth factor; CAPS; cancer associate protease; PLGA; poly (lactic-co-glycolic acid); ESMSVs; e
Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: AÂ Pooled Analysis from the M-Skip Project
Keywords: cAMP; cyclic adenosine monophosphate; MC1R; melanocortin-1 receptor; SOR; summary odds ratio; WT; wild-type;
Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease
Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; TREM2; the triggering receptor expressed on myeloid cells 2 gene; VPS35; the vacuolar protein sorting 35 gene; EIF4G1; the eukaryotic translation initiation factor 4-gamma 1 gene; S100B; the S100 calci
Niveles de 25-hidroxivitamina D en pacientes con melanoma y factores asociados con su insuficiencia
Keywords: 25-hidroxivitamina D; Colecalciferol; Melanoma; MC1R; Radiación ultravioleta; Obesidad; 25-Hydroxyvitamin D; Cholecalciferol; Melanoma; Melanocortin-1 receptor; Ultraviolet light; Obesity;
The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder
Keywords: Parkinson disease; Genetics; MC1R; Melanoma;
Polymorphisms in MC1R and ASIP genes and their association with coat color phenotypes in llamas (Lama glama)
Keywords: Llama; MC1R; ASIP; Polymorphisms; Coat color;
The study of nevi in children: Principles learned and implications for melanoma diagnosis
Keywords: adolescence; childhood; dermoscopy; detection; melanoma; nevi; nevogenesis; CI; confidence interval; Mc1R; melanocortin-1 receptor; OR; odds ratio; RHC; red hair color; SONIC; Study of Nevi in Children;
Histologic and Phenotypic Factors and MC1R Status Associated with BRAFV600E, BRAFV600K, and NRAS Mutations in a Community-Based Sample of 414 Cutaneous Melanomas
Keywords: CI; confidence interval; MC1R; melanocortin-1 receptor; NRHC; non-red hair color; OR; odds ratio; RHC; red hair color;
New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations
Keywords: ATP; adenosine triphosphate; BRAF; serine/threonine-protein kinase B-Raf; cAMP; cyclic adenosine monophosphate; CDK4; cyclin-dependent kinases 4; CREB; cAMP response element binding protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxi
Molecular cloning, mRNA expression and tissue distribution analysis of Slc7a11 gene in alpaca (Lama paco) skins associated with different coat colors
Keywords: Slc7a11; solute carrier family 7 member 11; cDNA; DNA complementary to RNA; bp; base pair(s); AA_permease_2; amino acid permease; Asip; agouti signaling protein; Mc1r; melanocortin-1 receptor protein; Tyrp1; tyrosinase related protein 1; Tyr; tyrosinase;
MC1R variant alleles and malignant melanoma risk in Israel
Keywords: Ashkenazi Jews; Malignant melanoma risk; MC1R; Sequence variants
Activation of β2-adrenergic receptor by (R,Râ²)-4â²-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells
Keywords: AC; adenylate cyclase; α-MSH; α-melanocyte stimulating hormone; ANOVA; analysis of variance; AR; adrenergic receptor; ATR; ataxia telangiectasia and Rad3-related protein; BCA; bicinchoninic acid; cAMP; cyclic adenosine monophosphate; CI; cell index; CIM
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
Alpha-melanocyte stimulating hormone protects retinal pigment epithelium cells from oxidative stress through activation of melanocortin 1 receptor-Akt-mTOR signaling
Keywords: AMD; age-related macular degeneration; RPE; retinal pigment epithelium; α-MSH; α-melanocyte stimulating hormone; mTOR; mammalian target of rapamycin; MC1R; melanocortin 1 receptor; H2O2; hydrogen peroxide; Age related macular degeneration (AMD); Retinal
Association of MC1R genotypes with shank color traits in Korean native chicken
Keywords: Korean native chicken; MC1R; Shank color; SNP
Agouti signalling protein is an inverse agonist to the wildtype and agonist to the melanic variant of the melanocortin-1 receptor in the grey squirrel (Sciurus carolinensis)
Keywords: MC1R; melanocortin-1receptor; MC1R-wt; melanocortin-1 receptor of the wildtype; MC1RÎ24; mutant melanocortin-1 receptor with 24 base pair deletion; ASIP; agouti signalling protein; POMC; pro-opiomelanocortin; CREB; cAMP responsive element binding protein
Hydroalcoholic extract of Rhodiola rosea L. (Crassulaceae) and its hydrolysate inhibit melanogenesis in B16F0 cells by regulating the CREB/MITF/tyrosinase pathway
Keywords: Rhodiola rosea; Melanin; Tyrosinase; MC1R; CREB; GSK3β;
Características clínicas de los pacientes con melanoma cutáneo en función de las variaciones en el gen del receptor 1 de la melanocortina (MC1R)
Keywords: Melanoma; Epidemiología; Predisposición genética; MC1RMelanoma; Epidemiology; Genetic predisposition; MC1R
Short CommunicationSequence variation in the Mc1r gene for a group of polymorphic snakes
Keywords: Mc1r; melanocortin-1 receptor; Mc1r; Melanin; Color pattern polymorphism; Black banding;
Pleiotropic effects of coat colour-associated mutations in humans, mice and other mammals
Keywords: αMSH; alpha-melanocyte-stimulating hormone; AS; Angelman syndrome; ATRN; Attractin (mahogany); ASIP; Agouti signalling protein; BLOC; Biogenesis of lysosomal organelles complex; CCSD; Canine congenital sensorineural deafness; CHS; Chediak-Higashi syndrom
Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation
Keywords: Melanin; Eumelanin; Barrier function; Folate; Vitamin D; 5-MTFH; 5-methyltetrahydrofolate; 7-DHC; 7-dehydrocholesterol; 25(OH)D; 25-hydroxycholecalciferol, or 25-hydroxyvitamin D, or serum vitamin D; ASIP; agouti signaling protein; DHFR; dihydrofolate red
Progression of disability in multiple sclerosis: A study of factors influencing median time to reach an EDSS value
Keywords: Ultraviolet radiation; Multiple sclerosis; EDSS; MC1R; Disability evaluation
Characterization of a novel tyrosinase inhibitor, (2RS,4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid (MHY384)
Keywords: ANOVA; Analysis of variance; CREB; cAMP responsive element binding protein; CO2; Carbon dioxide; CBP; CREB-binding protein; cAMP; Cyclic adenosine monophosphate; CDCl3; Deuterated chloroform; l-DOPA; l-3,4-dihydroxyphenylalanine; DMSO; Dimethyl sulfoxide;
Analysis of polymorphisms in the agouti signalling protein (ASIP) and melanocortin 1 receptor (MC1R) genes and association with coat colours in two Pramenka sheep types
Keywords: ASIP; Coat colour; MC1R; Polymorphisms; Pramenka sheep;
MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in Southern European populations: Results from a Meta-analysis
Keywords: MC1R; SLC45A2; TYR; Polymorphism; Meta-analysis;
Assessing diversity losses due to selection for coat colour in the endangered bay-Asturcón pony using microsatellites
Keywords: Conservation; MC1r; ASIP; Gene diversity; Allelic richness
Melanocortin receptors and their accessory proteins
Keywords: MC1R; MC2R; MC3R; MC4R; MC5R; MRAP; MRAP2;
Melanocortin MC1 receptor in human genetics and model systems
Keywords: MC1R; Melanoma; Red hair colour; Melanocyte; Tanning; Pigmentation
Unexpectedly Severe Acute Radiotherapy Side Effects Are Associated With Single Nucleotide Polymorphisms of the Melanocortin-1 Receptor
Keywords: Acute radiation reaction; MC1R; single nucleotide polymorphisms; R160W; predictive assays;