Keywords: α-MSH; α-melanocyte-stimulating hormone; E-cig18; e-vapour from nicotine containing e-fluid; E-cig0; nicotine-free e-vapour; iNOS; inducible nitric oxide synthases; MCR; melanocortin receptors; NPY; neuropeptide Y; Y1R; NPY Y1 receptor; POMC; proopiomel
مقالات ISI (ترجمه نشده)
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Keywords: Feline; MC4R; MRAP2; α-MSH; Interaction; Glycosylation;
Keywords: α-MSH; α-melanocyte stimulating hormone; AGRP; agouti related protein; ARC; arcuate nucleus of hypothalamus; ATF; activating transcription factor; BBB; blood-brain barrier; CRH; corticotropin-releasing hormone; CSF; cerebrospinal fluid; Cys; cysteine; D
Keywords: Estrogen; MC4R; Energy homeostasis; Reproduction;
Keywords: GWAS; genome-wide association study; SNPs; single nucleotide polymorphisms; JHS; Jackson Heart Study; BMI; body mass index; MDR; multifactor dimensionality reduction; SE; standard error; MAF; minor allele frequency; HWE; Hardy-Weinberg equilibrium; LD; li
Keywords: MC4R; Liver regeneration; pERK; pSTAT3
Keywords: ACTH; adrenocorticotropic hormone; AgRP; agouti-related protein; ARC; arcuate nucleus; cAMP; cyclic adenosine monophosphate; CCK; cholecystokinin; CNS; central nervous system; GPCR; G protein-coupled receptor; MCR; melanocortin receptor; MC4R; melanocorti
Keywords: MC4R; Nucleus accumbens; Voluntary wheel running; Dopamine; Obesity; Diabetes; Food intake
Keywords: AgRP; agouti-related peptide; α-MSH; α-melanocyte stimulating hormone; CNS; central nervous system; COR; Contrave Obesity Research; DIO; diet-induced obese; fMRI; functional magnetic resonance imaging; MC4R; melanocortin-4 receptor; MOP-R; μ-opioid rec
Keywords: αMSH; α-melanocyte stimulating hormone; ACTH; adrenocorticotrophic hormone; AgRP; agouti-related peptide; ARC; arcuate nucleus; AVPV; anteroventral periventricular area; BMI; body mass index; BMR; basal metabolic rate; CART; cocaine amphetamine related
Melanocortin-4 receptor in swamp eel (Monopterus albus): Cloning, tissue distribution, and pharmacology
Keywords: ACTH; Adrenocorticotropic hormone; AgRP; Agouti-related protein; α-MSH; α-melanocyte-stimulating hormone; BSA; bovine serum albumin; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CNS; central nervous system; DMEM; Dulbecco's Modified Eagle Medium; ECL
Weight gain prevention buffers the impact of CETP rs3764261 on high density lipoprotein cholesterol in young adulthood: The Study of Novel Approaches to Weight Gain Prevention (SNAP)
Keywords: Prevention; Body mass index; Genetics; High-density lipoprotein cholesterol; Young adulthood; ADCY3; Adenylate Cyclase 3; ATP2A1; ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 1; BCDIN3D; BCDIN3 Domain Containing RNA Methyltransferase; BDNF;
Neuroinflammation produced by heavy alcohol intake is due to loops of interactions between Toll-like 4 and TNF receptors, peroxisome proliferator-activated receptors and the central melanocortin system: A novel hypothesis and new therapeutic avenues
Keywords: PPAR; Neuroinflammation; Anti-inflammation; Ethanol intake; TLR4; Melanocortin system; MC4R;
The G protein-coupled receptors deorphanization landscape
Keywords: GPCRs; G protein-coupled receptors; GRK; GPCR kinase; IUPHAR; International Union of Basic and Clinical Pharmacology; BPS; British Pharmacological Society; CTR; Calcitonin receptor; CLR; CT Receptor-like; RAMP; Receptor Activity-Modifying Proteins; β2AR;
Adipocytes spectrum - From homeostasia to obesity and its associated pathology
Keywords: Acrp30 (AdipoQ); adiponectin gene; AdipoR; adiponectin receptor; AGE; angiotensinogen; ALP; alkaline phosphatase; Ang II; angiotensin II; Angptl2; angiopoietin-like protein-2; Aqp7; aquaporin-7; aP2; adipocyte-specific fatty acid binding protein 2 gene; A
Fructo-oligosaccharides reduce energy intake but do not affect adiposity in rats fed a low-fat diet but increase energy intake and reduce fat mass in rats fed a high-fat diet
Keywords: Fructo-oligosaccharide; High-protein diet; High-fat diet; Energy intake; Adiposity; exp1; experiment 1; exp2; experiment 2; NP; normal protein normal fat; NP-FOS; normal protein normal fat with fructo-oligosaccharide; HP; high protein normal fat; HP-FOS;
Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat
Keywords: α-MSH; Melanocortin; MC4R; Agonist; Tetrapeptide; Food intake;
Feedback from Arctic charr: Feed flavour stimulation and re-feeding after feed deprivation stimulate genes encoding both orexigenic and anorexigenic neuropeptides
Keywords: Teleosts; Appetite regulation; Gene expression; Feed deprivation; Flavour stimulation; Hypothalamic appetite regulators; AgRP; MC4R; CART;
Associations between single-nucleotide polymorphisms of melanocortin gene and sexual desire behavior in rabbit (Oryctolagus cuniculus)
Keywords: V-line; MC4R; sexual desire; SNPs; prediction;
Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population
Keywords: BMI; body mass index; GWAS; genome-wide association study; SNP; single-nucleotide polymorphism; WC; waist circumference; WtHR; waist-to-height ratio; SD; standard deviations; GRS; genetic risk score; SBP; systolic blood pressure; DBP; diastolic blood pres
Pharmacological chaperones for the misfolded melanocortin-4 receptor associated with human obesity
Keywords: AgRP; agouti-related peptide; V2R; vasopressin V2 receptor; CFTR; cystic fibrosis transmembrane conductance regulator; ER; endoplasmic reticulum; GnRHR; gonadotropin-releasing hormone receptor; GPCR; G protein-coupled receptor; Hsc70; cytosolic cognate 70
Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer
Keywords: BMI; body mass index; CCFR; Colon Cancer Family Registry; CI; confidence interval; FTO; fat-mass and obesity-associated; GECCO; Genetics and Epidemiology of Colorectal Cancer Consortium; GWAS; genome-wide association study; MAF; minor allele frequency; MC
Association study between near-MC4R variants and obesity-related variables in Portuguese young adults
Keywords: GWAS; genome-wide association studies; BMI; body mass index; MC4R; melanocortin-4 receptor gene; WC; waist circumference; WHO; World Health Organization; RFLP; restriction fragment length polymorphism; FTO; fat-mass and obesity-associated gene; MC4R gene;
Association of FTO and near MC4R variants with obesity measures in urban and rural dwelling Sri Lankans
Keywords: FTO; MC4R; Single nucleotide polymorphism; Obesity; Sri Lankan;
Changes in body weight and fatness of sows during reproductive activity depending on LEPR and MC4R genes polymorphism
Keywords: Condition; Rearing of piglets; Three reproductive cycles; LEPR; MC4R
The association of MC4R rs17782313 polymorphism with dietary intake in Iranian adults
Keywords: BMI; Body Mass Index; GPAQ; Global Physical Activity Questionnaire; IMOS; Iranian Multicenter Osteoporosis Study; MC4R; melanocortin 4 receptor; PA; physical activity; PCR; polymerase chain reaction; PCR-RFLP; polymerase chain reaction-restriction fragmen
Novel polymorphisms in the 5′UTR of FASN, GPAM, MC4R and PLIN1 ovine candidate genes: Relationship with gene expression and diet
Keywords: Sheep; FASN; GPAM; MC4R; PLIN; Polymorphisms
Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition
Keywords: SNP; single nucleotide polymorphism; FABP3; fatty acid binding protein 3; HMGA1; high mobility group AT-hook 1; MC4R; melanocortin-4 receptor; IGF2; insulin-like growth factor-2; FABP4; fatty acid binding protein 4; QTL; quantitative trait locus; SFA; sat
Three novel MC4R SNPs associated with growth traits in Hu sheep and East Friesian à Hu crossbred sheep
Keywords: MC4R; Sheep; SNP; Haplotype; Growth traits;
Chronic delivery of α-melanocyte-stimulating hormone in rat hypothalamus using albumin-alginate microparticles: Effects on food intake and body weight
Keywords: α-MSH; α-melanocyte-stimulating hormone; ANOVA; analysis of variance; CSF; cerebro-spinal fluid; DDS; drug delivery system; FITC; fluorescein isothiocyanate; HSA; human serum albumin; HSA-alg MP; HSA-alginate microparticles; MC4R; melanocortin receptor
Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus
Keywords: α-MSH; α-melanocyte-stimulating hormone; AC; adenylate cyclase; BDNF; brain-derived neurotrophic factor; CREB; cAMP responsive element binding protein; DAPI; 4â²,6-diamido-2-phenylindole dihydrochloride; ERK; extracellular signal-regulated kinase; GFAP
Transcriptomic analysis of Rongchang pig brains and livers
Keywords: RNA-seq; RNA sequencing; DEGs; differentially expressed genes; NMS; neuromedin S; MSH; melanocyte-stimulating hormone; ECLP; extracorporeal liver perfusion; SAGE; serial analysis of gene expression; IGFBPs; insulin-like growth factor binding proteins; qRT
Regulation of the mesocorticolimbic and mesostriatal dopamine systems by α-melanocyte stimulating hormone and agouti-related protein
Keywords: αMSH; AgRP; Dopamine; Feeding; Drug abuse; Melanocortin; MC3R; MC4R; VTA;
The FTO gene polymorphism (rs9939609) is associated with metabolic syndrome in morbidly obese subjects from southern Italy
Keywords: Morbid obesity; SNPs; FTO; MC4R; SIRT1; metabolic syndrome
Research ReportProlyl carboxypeptidase mRNA expression in the mouse brain
Keywords: PRCP: CNS; Central Nervous System; Prolyl carboxypeptidase; α-MSH: alpha-melanocyte stimulating hormone; MC3R; melanocortin 3 receptor; MC4R; melanocortin 4 receptor; Lv; lateral ventricle; 3v; third ventricle; 4v; fourth ventricle; HP; hippocampus; HY
5â²Cis regulatory polymorphisms in candidate genes in Bos taurus and Bos indicus
Keywords: FASN; GPAM; MC4R; SCD; PLIN; Functional polymorphisms;
Association between melanocortin 4 receptor (MC4R) gene haplotypes and carcass and production traits in Italian Large White pigs evaluated with a selective genotyping approach
Keywords: MC4R; Haplotypes; SNP; Back fat thickness; Average daily gain; Association study;
Melanocortin MC4 receptor-mediated feeding and grooming in rodents
Keywords: Melanocortin MC4 receptor; MC4R; MSH; ACTH; Grooming; Food intake; Body weight;
N-acylation of phosphatidylethanolamine and its biological functions in mammals
Keywords: NAE; N-acylethanolamine; PA; phosphatidic acid; OEA; N-oleoylethanolamine; PEA; N-palmitoylethanolamine; LEA; N-linoleoylethanolamine; AEA; N-arachidonoylethanolamine; SEA; N-stearoylethanolamine; NAPE; N-acylphosphatidylethanolamine; pNAPE; N-acylplasmen
Food-intake dysregulation in type 2 diabetic Goto-Kakizaki rats: Hypothesized role of dysfunctional brainstem thyrotropin-releasing hormone and impaired vagal output
Keywords: AgRP; agouti-related peptide; Amb; nucleus ambiguus; AP; area postrema; BW; body weight; DMV; dorsal motor nucleus of the vagus; DVC; dorsal vagal complex; F48h; 48Â h fasted; GHSR; ghrelin receptor; GIP; glucose-dependent insulinotropic polypeptide; GK r
Angiotensin-converting enzyme inhibition reduces food intake and weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats
Keywords: Melanocortin; MC4R; ACE inhibitor; Renin–angiotensin system; Captopril
Evolution of melanocortin receptors in cartilaginous fish: Melanocortin receptors and the stress axis in elasmobranches
Keywords: MCR; MC3R; MC4R; MC5R; Cartilaginous fish; Evolution
Dog obesity – The need for identifying predisposing genetic markers
Keywords: Dog; Human; Obesity; FTO; MC4R; Adipokines
Inhibiting neuropeptide Y Y1 receptor modulates melanocortin receptor- and NF-κB-mediated feeding behavior in phenylpropanolamine-treated rats
Keywords: NPY Y1 receptor; NF-κB; NPY; MC4R; Hypothalamus
Weight-Independent Effects of Roux-en-Y Gastric Bypass on Glucose Homeostasis via Melanocortin-4 Receptors in Mice and Humans
Keywords: Weight-Loss Surgery; Stomach; Mouse Model; Insulin Sensitivity; CRWM-sham; calorie-restricted, weight-matched sham; DIO; diet-induced obesity; DMV; dorsal motor vagus; HFD; high-fat diet; HOMA-IR; homeostasis model assessment - insulin resistance; IML; in
High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families
Keywords: Monogenic obesity; Congenital leptin deficiency; LEP; MC4R; Consanguinity
Characterization of neuropeptide Y in snakeskin gourami and the change in its expression due to feeding status and melanocortin 4 receptor expression
Keywords: Neuropeptide Y; NPY; MC4R; Gourami; Circadian feeding; Post-prandial;
Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc × Iberian crossbred pigs
Keywords: MC4R; LEPR; Meat quality; Heavy pigs; Duroc; Iberian
Gonadotropin-releasing hormone II (GnRH II) mediates the anorexigenic actions of α-melanocyte-stimulating hormone (α-MSH) and corticotropin-releasing hormone (CRH) in goldfish
Keywords: Goldfish; GnRH II; Anorexigenic action; MC4R; MT II; CRH receptor; GnRH receptor; Antide
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist
Keywords: Melanocortin subtype-4 receptor; MC4R; Partial agonist; Urea piperazine; Erectile dysfunction; Obesity