
Modifications on the hydrogen bond network by mutations of Escherichia coli copper efflux oxidase affect the process of proton transfer to dioxygen leading to alterations of enzymatic activities
Keywords: CueO, copper efflux oxidase; MCO, multicopper oxidase; E. coli, Escherichia coli; T1, type I; T2, type II; T3, type III; TNC, trinuclear copper center; BO, bilirubin oxidase; CD, circular dichroism; EPR, electron paramagnetic resonance; BCA, bicinchoninic