Keywords: Cathepsins; Endo-lysosomes; Mct8; Mct10; Thyroid auto-regulation; Thyroid states; Thyroxine; Translocation across membranes;
مقالات ISI (ترجمه نشده)
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Keywords: Brain; Neuron; Thyroid hormone transport; Mct8; Deiodinase; T4; thyroxine; T3; 3,5,3â²-triiodothyronine; TH; thyroid hormones; 3,5-T2; 3,5-diiodothyronine; 3,3â²-T2; 3,3â²-diiodothyronine; 3-T1AM; 3-iodothyronamine; Tbg; thyroxin-binding globuline; Ttr
Keywords: gLE; genetic leukoencephalopathy; CNS; central nervous system; MRI; magnetic resonance imaging; MSUD; Maple Syrup Urine Disease; ClC-2; Chloride Ion Channel 2; MLC; Megalencephalic Leukoencephalopathy with subcortical cysts; X-ALD; X-linked Adrenoleukodys
Keywords: thyroid hormone cell-membrane transporter; MCT8; Allan–Herndon–Dudley syndrome; deiodinase; selenoprotein; SBP2
Knockdown of the thyroid hormone transporter MCT8 in chicken retinal precursor cells hampers early retinal development and results in a shift towards more UV/blue cones at the expense of green/red cones
Keywords: Thyroid hormone; Monocarboxylate transporter 8; Retina; Development; Chicken embryo; RNA interference; AP; alkaline phosphatase; BRN3a; brain-specific homeobox/POU domain protein 3a; CNS; central nervous system; CRX; Cone-Rod homeobox; DAC; displaced amac
From zebrafish to human: A comparative approach to elucidate the role of the thyroid hormone transporter MCT8 during brain development
Keywords: Thyroid hormone; MCT8; Brain development; Animal model; AHDS;
Zebrafish - An emerging model to explore thyroid hormone transporters and psychomotor retardation
Keywords: Zebrafish; Thyroid transporters; Thyroid hormone analogues; MCT8; OATP1C1; Mental retardation; THs; thyroid hormones; THTTs; thyroid hormone transmembrane transporters; MCT; monocarboxylate transporter; OATP1C1; organic anion transporting polypeptide 1C1;
Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes
Keywords: Thyroid hormone; Thyroid hormone analogues; Resistance to thyroid hormone; RTH-Beta; AHDS; MCT8; Triac; Tetrac; DITPA; TH; thyroid hormone; T3; 3,3â²,5-triiodothyronine; TR; T3-receptors; RTH; resistance to thyroid hormone; Triac; 3,3â²,5-triiodothyroac
Application of a nonradioactive assay for high throughput screening for inhibition of thyroid hormone uptake via the transmembrane transporter MCT8
Keywords: MCT8; High throughput screening; Thyroid hormone disruptors; Bisphenol A (BPA);
The long N-terminus of the human monocarboxylate transporter 8 is a target of ubiquitin-dependent proteasomal degradation which regulates protein expression and oligomerization capacity
Keywords: MCT8; N-terminus; Ubiquitination; Degradation; Oligomerizationaa, amino acid; AHDS, Allan-Herndon-Dudley Syndrome; GFP, green fluorescent protein; MCT8, monocarboxylate transporter 8; MFS, major facilitator superfamily; reverse T3, 3,3′,5′-tri-iodothyroni
Allan-Herndon-Dudley syndrome (AHDS) in two consecutive generations caused by a missense MCT8 gene mutation. Phenotypic variability with the presence of normal serum T3 levels
Keywords: AHDS; MCT8; Thyroid hormone; Phenotype; Variability; Mental retardation;
The thyroid hormone transporters MCT8 and MCT10 transport the affinity-label N-bromoacetyl-[125I]T3 but are not modified by it
Keywords: Monocarboxylate transporter 8; Monocarboxylate transporter 10; MCT8; MCT10; Thyroid hormone transport; Affinity-label N-bromoacetyl-[125I]T3; Inhibition studies
MCT8: From gene to disease and therapeutic approach
Keywords: MCT8; Transporteurs des hormones thyroïdiennes; T3; Retard psychomoteur; Syndrome d'Allan-Herndon-Dudley; MCT8; Thyroid hormone transporters; T3; Psychomotor retardation; Allan-Herndon-Dudley syndrome;
Síndromes de resistencia a las hormonas tiroideas
Keywords: Hipotiroidismo; Transportadores de membrana; Desyodasas; Déficit intelectual; Receptores nucleares; MCT8Hypothyroidism; Membrane transporters; Deiodinases; Intellectual deficit; Nuclear receptors; MCT8
Genetics and phenomics of thyroid hormone transport by MCT8
Keywords: X-linked mental retardation; MCT8; Thyroid hormone transport
Thyroid hormone action during brain development: More questions than answers
Keywords: Central nervous system; Neuronal differentiation; Thyroid hormone receptor; Deiodinase; Thyroid hormone transporter; MCT8
Iodothyronine deiodinase enzyme activities in bone
Keywords: Thyroid hormone metabolism; MCT8; Chondrocyte; Osteoblast; Osteoclast;
Think globally: Act locally: New insights into the local regulation of thyroid hormone availability challenge long accepted dogmas
Keywords: Deiodinase; Mct8; Regulation; Obesity; Bile acids
The importance of thyroid hormone transporters for brain development and function
Keywords: iodothyronine deiodinases; MCT8; OATP1c1; X-linked psychomotor retardation
Placental transport of thyroid hormone
Keywords: L-type amino acid transporters; MCT8; organic anion transporters; placenta; thyroid hormone; transporters
Thyroid hormone transport by monocarboxylate transporters
Keywords: MCT; MCT8; MCT10; monocarboxylate transporter; TAT1; thyroid hormone transporter
The MCT8 thyroid hormone transporter and Allan–Herndon–Dudley syndrome
Keywords: Allan–Herndon–Dudley syndrome; MCT8; T3; thyroid hormone transporter
Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination
Keywords: deiodinases; MCT8; metabolism; receptor; resistance; SECISBP2/SBP2; selenoproteins; thyroid hormone; transmembrane transport
Syndromes of hormone resistance in the hypothalamic–pituitary–thyroid axis
Keywords: TRH; TSH; thyroid hormones; transporter; MCT8; deiodinases; SECISBP2