Keywords: FPP; farnesyl pyrophosphate; FPPS; farnesyl pyrophosphate synthase; GPP; geranyl diphosphate; HMG-CoA reductase; 3-hydroxy-3-methylglutaryl-CoA reductase; IPP; isopentenyl diphosphate; MDD; mevalonate 5-diphosphate decarboxylase, also known as mevalonate
مقالات ISI (ترجمه نشده)
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Keywords: AgRP; agouti-related protein; ANOVA; analysis of variance; b-FGF; basic fibroblast growth factor; BMI; body mass index; BTC; betacellulin; CI; Confidence interval; CRF; corticotropin-releasing factor; CRP; C reactive protein; CTE; childhood trauma exposur
Keywords: 2-DE; two-dimensional electrophoresis; ALPFC; anterolateral PFC; ANXA3; annexin A3; CUMS; chronic unpredictable mild stress; DLPFC; dorsolateral PFC; DPYSL2; dihydropyrimidinase-related protein 2; ETC; electron transport chain; GAPDH; glyceraldehyde-3-pho
Keywords: CHAPS; 3-(3-cholamidopropyl)dimethylammonio)-1-propanesulfonic acid; CVD; Cardiovascular diseases; C; Control; 2-D; two-dimension; DNPH; 2,4-dinitrophenylhydrazine; DTT; dithiothreitol; ERR-α; estrogen-related receptor-α; FBS; fetal bovine serum; FC; Fo
Keywords: Glutamate; Antidepressant; Anxiolytic; Analgesic; Ketamine; STAR*D; Receptor occupancy; MOA; mechanism of action; NAM; negative allosteric modulator; PPS; painful physical symptoms; MDD; major depressive disorder; STAR*D; sequenced treatment alternatives
Keywords: BMI; Body mass index; UW; Underweight; NW; Normal weight; OW; Overweight; OB; Obesity; FFAs; free fatty acids (FFAs); Trp; tryptophan; MDD; major depression disorders; HR; Hazard ratio; PR; prevalence ratio; OR; odds ratio; SES; Socioeconomic status; PA;
Keywords: AOR; adjusted odd ratio; AUD; alcohol use disorder; BD; bipolar I disorder; CI; confidence interval; GAD; generalized anxiety disorder; MDD; major depressive disorder; OR; odd ratio; PTSD; post-traumatic stress disorder; SE; sensitivity; SP; specificity;
Keywords: Depression; MDD; Biological clock; Circadian rhythms; Cryptochrome; TMS; PEMF; tPEMF; Weak electromagnetic fields
Keywords: SOA; WSDL; WADL; MDA; MDD
Keywords: AHA; American Heart Association; ATP; third adult treatment panel; BMI; body mass index; CVD; cardiovascular disease; DBP; diastolic blood pressure; ETB; Ethiopian Birr; FFA; free fatty acid; HDL; high density lipoprotein; IDF; International Diabetes Fede
Differentiating responders and non-responders to rTMS treatment for depression after one week using resting EEG connectivity measures
Keywords: Transcranial magnetic stimulation; Treatment resistant depression; Electroencephalography; Theta; Alpha; rTMS; repetitive transcranial magnetic stimulation; fMRI; functional magnetic resonance imaging; ACC; anterior cingulate cortex; DLPFC; dorsolateral p
Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis
Keywords: IBGE; Brazilian Institute of Geography and Statistics; ILAE; International League Against Epilepsy; MRI; magnetic resonance imaging; MDD; major depressive disorder; DSM-IV-TR; Multiaxial Diagnostic and Statistical Manual; PCR; polynucleotide chain reactio
Patient centric measures for a patient centric era: Agreement and convergent between ratings on The Patient Global Impression of Improvement (PGI-I) scale and the Clinical Global Impressions - Improvement (CGI-S) scale in bipolar and major depressive diso
Keywords: CGI-I; clinician global impression scale of improvement; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition; ICH-GCP; International Conference of Harmonisation for Good Clinical Practice Guidelines; ICC; Intraclass Correlation
Glycogen synthase kinase-3β genetic polymorphisms and insomnia in depressed patients: A prospective study
Keywords: GSK3B; Single nucleotide polymorphism; Insomnia; Antidepressants response; MDD; MDE;
Investigating the metabolic alterations in a depressive-like rat model of chronic forced swim stress: An in vivo proton magnetic resonance spectroscopy study at 7T
Keywords: In vivo proton magnetic resonance spectroscopy (1H MRS); Major depressive disorders; Chronic forced swim stress; MDD; major depressive disorder; 1H MRS; proton magnetic resonance spectroscopy; Cho; choline-compounds; mIns; myo-inositol; Cr; creatine; Glu
Baicalin exerts neuroprotective effects via inhibiting activation of GSK3β/NF-κB/NLRP3 signal pathway in a rat model of depression
Keywords: MDD; major depressive disorder; HPA; Hypothalamus-Pituitary-Adrenal; CNS; central nervous system; NSCs; neural stem cells; DG; dentate gyrus; CUMS; chronic unpredictable mild stress; BA; Baicalin; SPT; sucrose preference test; FST; forced swimming test; O
High-frequency repetitive TMS for suicidal ideation in adolescents with depression
Keywords: Adolescent; Brain stimulation; Depression; Suicidality; Suicidal ideation; Transcranial magnetic stimulation; ATHF; Antidepressant treatment history form; CDRS-R; Children's depression rating scale, revised; CGI-S; Clinical global impression-severity scal
A Randomized, Double-Blind, Placebo-Controlled Trial of Escitalopram in Patients with Asthma and Major Depressive Disorder
Keywords: Major depressive disorder; Asthma; Escitalopram; Selective serotonin reuptake inhibitor; ACQ; Asthma Control Questionnaire; HRSD17; 17-item Hamilton Rating Scale for Depression; IDS-SR; Inventory of Depressive Symptomatology-Self-Report; MDD; Major depres
Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress
Keywords: Depression; D-Serine; Serine racemase; Stress resilience; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; CSDS; chronic social defeat stress; CSF; cerebrospinal fluid; DG; dentate gyrus; ECL; enhanced chemiluminescence; FST; forced swi
Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults
Keywords: Depression; Major depressive disorder; MDD; Gene expression; WGCNA; Transcriptome;
Symptoms of depression and anxiety and 11-year all-cause mortality in men and women undergoing coronary artery bypass graft (CABG) surgery
Keywords: Anxiety; Depression; Cardiovascular disease; Mortality; Multicenter study; Sex; CABG; Coronary artery bypass graft; CR; Cardiac rehabilitation; HADS; Hospital Depression and Anxiety Scale; HADS-D; Hospital Depression and Anxiety Scale - depression subscal
Application of machine learning classification for structural brain MRI in mood disorders: Critical review from a clinical perspective
Keywords: BD; bipolar disorder; MDD; major depressive disorder; MRI; magnetic resonance imaging; sMRI; structural MRI; fMRI; functional MRI; SVM; support vector machine; PCA; principal component analysis; ROI; regions of interest; RVM; relevance vector machine; GPC
Sprint interval training (SIT) substantially reduces depressive symptoms in major depressive disorder (MDD): A randomized controlled trial
Keywords: Exercise training; Intermittent exercise; Interval training; Inpatient; Depressive disorder; Depression; BDI-II; Beck Depression Inventory; BDNF; brain-derived neurotrophic factor; BMI; Body Mass Index; CAT; Continuous aerobic exercise training; f; respir
Methodology for the model-driven development of service oriented IoT applications
Keywords: Thing; IoT; MDD; SOA; Transformation;
Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies
Keywords: Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe
Factorial structure and familial aggregation of the Hypomania Checklist-32 (HCL-32): Results of the NIMH Family Study of Affective Spectrum Disorders
Keywords: BD; bipolar disorder; HCL-32; Hypomania Checklist-32; MDD; major depressive disorder; NIMH; National Institute of Mental Health; NIH; National Institutes of Health; DIAS; NIMH Family Study Diagnostic Interview for Affective Spectrum Disorders; DIAS-FHX; N
Individuals with more severe depression fail to sustain nucleus accumbens activity to preferred music over time
Keywords: Ventral striatum; MDD; Classical music; Anhedonia; Major depression; fMRI; Mood induction;
Modulation of P2X7 purinergic receptor activity by extracellular Zn2+ in cultured mouse hippocampal astroglia
Keywords: CNS; central nervous system; MDD; major depressive disorder; BzATP; 3â²-O-(4-Benzoyl) benzoyl ATP; BBG; Brilliant Blue G; OGB-1; OregonGreen Bapta-1; PI; propidium iodide; VGluT1; vesicularglutamate transporter 1; P2X7R; Hippocampus; Purinergic receptor;
Histone deacetylases (HDACs) as therapeutic target for depressive disorders
Keywords: Depression; Epigenetic modifications; Histone deacetylase inhibitors; HDACs; MDD; Antidepressants;
Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway
Keywords: Agmatine; Akt; HT22; Ketamine; Neuroprotection; p70S6 kinase; PSD95; 4E-BPs; 4E binding proteins; ANOVA; analysis of variance; DMEM; Dulbecco's Modified Eagle Medium; ECT; electroconvulsive therapy; CUS; chronic unpredictable stress; FST; forced swim test
The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices
Keywords: BOLD; blood oxygenation level dependent; fMRI; functional magnetic resonance imaging; GABA; γ-aminobutyric acid; IPSC; inhibitory post synaptic current; MDD; major depressive disorder; serotonin; 5-HT; SNRI; serotonin norepinephrine reuptake inhibitor; S
Solution NMR views of dynamical ordering of biomacromolecules
Keywords: ALS; Amyotrophic Lateral Sclerosis; CPMG; Carr-Purcell-Meiboom-Gill; CPP; Cell Penetrating Peptide; CHO; Chinese Hamster Ovary Cells; Rex; Chemical/Conformational Exchange; (C)EST; (Chemical) Exchange Saturation Transfer; CSA; Chemical Shift Anisotropy; C
Functionalized liposomes and phytosomes loading Annona muricata L. aqueous extract: Potential nanoshuttles for brain-delivery of phenolic compounds
Keywords: Annona muricata L.; Phytosomes; Liposomes; mApoE; hMAO-A; Hydrogen peroxide scavenging; AE; aqueous extract; ApoE; apolipoprotein E; BBB; blood-brain barrier; CNS; central nervous system; DCM; dichloromethane; DMSO; dimethylsulfoxide; DSPE-PEG-maleimide;
Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice
Keywords: Major depression; Nicotinic receptor; Microglia; α7 positive allosteric modulator; Neuroinflammation; Mice; MDD; major depressive disorder; CNS; central nervous system; LPS; lipopolysaccharide; nAChR; nicotinic acetylcholine receptor; PAM; positive allos
Curcumin Protects Against Chronic Stress-induced Dysregulation of Neuroplasticity and Depression-like Behaviors via Suppressing IL-1β Pathway in Rats
Keywords: ADF; actin-depolymerizing factor; CIN; chronophin; CNS; central nervous system; CUMS; chronic unpredictable mild stress; ELISA; enzyme-linked immunosorbent assay; LIMKs; LIM-kinases; MDD; major depressive disorder; mPFC; medial prefrontal cortex; PDTC; py
Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition
Keywords: Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure
Archival ReportNonsynonymous Variation in NKPD1 Increases Depressive Symptoms in European Populations
Keywords: CESD; Depressive symptoms; Exome sequencing; Major depression; MDD; NKPD1;
Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression
Keywords: GWA studies; genome-wide association studies; SNP; single nucleotide polymorphism; MDD; major depressive disorder; TAS; trait/disease-associated SNP; lncRNA; long noncoding RNA; DSM-IV; Diagnostic and Statistical Manual of Mental Disorders Fourth Edition;
Perfluoroalkyl substance exposure and urine CC16 levels among asthmatics: A case-control study of children
Keywords: CC16; The 16-kDa club cell secretory protein; ETS; Environmental tobacco smoke; GBCA; Genetics and Biomarkers study for Childhood Asthma; LOD; limit of detection; LOQ; limit of quantification; MDD; minimum detectable dose; NHANES; US National Health and E
Research paperAbnormal functional connectivity within resting-state networks is related to rTMS-based therapy effects of treatment resistant depression: A pilot study
Keywords: MDD; major depressive disorder; TRD; treatment resistant depression; fMRI; functional magnetic resonance imaging; rTMS; repetitive transcranial magnetic stimulation; ICA; independent component analysis; ROC; receiver operating characteristic; HRSD; Hamilt
Three-dimensional components of selfhood in treatment-naive patients with major depressive disorder: A resting-state qEEG imaging study
Keywords: EEG; Electroencephalogram; DMN; Default Mode Network; OA; Operational Architectonics; OM; Operational Module; MDD; major depression disorder; HAM; Hamilton Depression Rating Scale; SCID; Structured Diagnostic Interview; SC; synchrocomplexes; RTP; rapid tr
Modulation of motor cortex excitability predicts antidepressant response to prefrontal cortex repetitive transcranial magnetic stimulation
Keywords: MDD; rTMS; Dorsolateral prefrontal cortex; Motor cortex; Excitability; Antidepressant response prediction; APB; abductor pollicis brevis muscle; AUC; area under the curve; BDI-II; 21-item Beck Depression Inventory-II; DLPFC; dorsolateral prefrontal cortex
Brain-derived neurotrophic factor Val66Met genotype modulates amygdala habituation
Keywords: BPD; borderline personality disorder; BDNF; brain-derived neurotrophic factor; fMRI; functional magnetic resonance imaging; SPD; schizotypal personality disorder; HC; healthy control; SNP; single nucleotide polymorphism; Val; valine; Met; methionine; PTSD
Research reportUp-regulation of SIRT6 in the hippocampus induced rats with depression-like behavior via the block Akt/GSK3β signaling pathway
Keywords: MDD; major depressive disorder; CNS; central nervous system; CUMS; chronic unpredictable mild stress; IPA; ingenuity pathway analysis; SPT; sucrose preference test; BW; body weight; FST; forced swimming test; OFT; open field test; RT; retention time; RT-q
Senegenin exerts anti-depression effect in mice induced by chronic un-predictable mild stress via inhibition of NF-κB regulating NLRP3 signal pathway
Keywords: SEN; senegenin; Flu; fluoxetine; MDD; major depressive disorder; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; CUMS; chronic unpredictable mild stress; BDNF; brain-derived neurotrophic factor; NT-3; neurotrophins-3; NLRP3; NOD-like receptor p
Research reportRole of proBDNF and BDNF in dendritic spine plasticity and depressive-like behaviors induced by an animal model of depression
Keywords: BDNF; brain-derived neurotrophic factor; MDD; major depressive disorder; CUMS; chronic unpredicted mild stress; NR2B; NMDA receptor subtype 2B; PSD95; postsynaptic density protein 95; TrkB; tropomyosin-related kinase B; BDNF; proBDNF; Depression; Stress;
A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophrenia
Keywords: ECS; endocannabinoid system; MAM; methylazoxymethanol acetate; CNR1; gene coding for the type-1 cannabinoid receptor; PBMCs; human peripheral blood mononuclear cells; MDD; major depressive disorder; BD; bipolar disorder; SZ; schizophrenia; THC; tetrahydro
Priority CommunicationGenome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder
Keywords: Genome-wide analyses; Haplotype block; HRHM; MDD; Regional heritability; TOX2;
Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila
Keywords: 5-HT; serotonin; BP; biological process; CC; cellular component; Con; control flies; CPZ; flies fed with 2000Â mg/L of Chlorpromazine for 48Â h; DEGs; differentially expressed genes; dscDNA; double-strand cDNA; FXS; Fragile X syndrome; GO; Gene ontology;
P3b amplitude is not reduced in abstinent alcoholics with a current MDD
Keywords: Alcohol dependence; Self-medication; P3b; Major depressive disorder; AUD; alcohol-use disorders; MDD; major depressive disorder; LTAAs; long-term abstinent alcoholics; NSACs; non-substance abusing controls;