Keywords: میانگین دوز مرگبار; Mulberry leaf extract; Rat; Subacute toxicity; Genotoxicity; Ames assay; Micronucleus; Sperm abnormality; Safety assessment; 1,8-DHAQ; 1,8-dihydroxyanthraquinone; 2-AF; 2-aminofluorene; 4-NO; 4-nitro-O-phenylenediamine; ALB; albumin; ALP; alkalinephosphat
مقالات ISI میانگین دوز مرگبار (ترجمه نشده)
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Keywords: میانگین دوز مرگبار; Genetic differences; Nerve agents; Median lethal dose; Inbred strain panel; Mice; Phenotypes;
Keywords: میانگین دوز مرگبار; Aeromonas hydrophila; Poly(d,l-lactide-co-glycolic acid); Aquaculture; Microparticles; Misgurnus anguillicaudatus; Cyprinus carpio; FKC; formalin-killed whole-cell; PLGA; poly(d,l-lactide-co-glycolic acid); MPs; microparticles; W/O/W; water-in-oil-in-wate
Keywords: میانگین دوز مرگبار; ADP; adenosine diphosphate; ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; Bax; BCL2-associated X protein; Bcl-xL; B-cell lymphoma-extra large; CLP; cecal ligation and puncture; CyP; cyclophilin; DAMP; damage-associated molecular patte
Keywords: میانگین دوز مرگبار; CMC; critical micelle concentration; cryo-TEM; cryogenic transmission electron microscopy; DLS; dynamic light scattering; DPPC; dipalmitoyl phosphatidylcholine; DSC; differential scanning calorimetry; EC50; median effective concentration; HEPES; N-(2-Hydr
Keywords: میانگین دوز مرگبار; ARE; antioxidant response element; C.L.; confidence limit; CS50; current strength required to induce seizure response in 50% of mice; DMSO; dimethyl sulfoxide; ED50; median effective dose; ip; intraperitoneally; IS; internal standard; iv; intravenously; L
Keywords: میانگین دوز مرگبار; AUC; area under the curve; BZD; benzodiazepine; Cl; total clearance; Cmax; peak concentration; CNS; central nervous system; DOPAC; 3,4-dihydroxyphenylacetic acid; DZP; diazepam; GABA; γ-aminobutyric acid; EEG; electroencephalogram;; f; respiratory freque
Keywords: میانگین دوز مرگبار; 6-OHDA; 6-hydroxydopamine; ABTS; 2,2â²-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid); BSA; bovine serum albumin; CNS; central nervous system; CPu; caudate putamen; CXCL12; chemokine (C-X-C motif) ligand 12; CXCR4; chemokine (C-X-C motif) Rece
Keywords: میانگین دوز مرگبار; Piperaceae; Piper vicosanum; Essential oil; Acute toxicity; Genotoxicity; Inflammation; OPV; essential oil from P. vicosanum leaves; GC; gas chromatograph; GC-MS; mass spectrometer detector; OECD; Organisation for Economic Co-operation and Development;
Keywords: میانگین دوز مرگبار; VEE; Venezuelan equine encephalitis; MLT; Melatonin; MIN; Minocycline; AA; Ascorbic acid; NO; Nitric oxide; LD50; Median lethal dose; bw; Body weight; MDA; Malondialdehyde; Melatonin; Minocycline; Ascorbic acid; Viral replication; Oxidative stress; Mouse
Keywords: میانگین دوز مرگبار; Selenium; Selenate; High fat diet; Obesity; Insulin resistance; BAT; brown adipose tissue; C/EBP; CCAAT/enhancer binding protein; DGAT2; diacylglycerol acyltransferase 2; FAS; fatty acid synthase; H&E; haematoxylin and eosin; HF; high fat; HOMA-IR; homeos
Keywords: میانگین دوز مرگبار; ANOVA; one-way analysis of variance; bw; body weight; EGCG; epigallocatechin gallate; GTE; green tea extract; H&E; Hematoxylin & Eosin; IACUC; Institutional Animal Care and Use Committees; LD50; median lethal dose; LFP; lychee fruit extract; LOAEL; lowest
Keywords: میانگین دوز مرگبار; Genotoxins; Food toxicology; Yeast Comet Assay; Standard Comet Assay; 14-AAP; 4-aminoantipyrine; AF-2; furylfuramide; CA; standard Comet Assay; DMSO; dimethyl sulfoxide; LD50; median lethal dose; SCGE; Single Cell Gel Electrophoresis; YCA; Yeast Comet Ass
Keywords: میانگین دوز مرگبار; ADD; average daily dose; COPC; contaminant of potential concern; CR; concentration ratio; EA; environmental assessment; EFW; energy-from-waste; EHQ; environmental hazard quotient; EPC; exposure point concentration; ERA; environmental risk assessment; HHRA
Keywords: میانگین دوز مرگبار; 2-PAM Cl; pralidoxime chloride; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; BBB; blood brain barrier; ChE; cholinesterase; CNS; central nervous system; CWNA; chemical weapon nerve agent; FDA; Food and Drug Administration; HI-6 DMS; 1-(((4-(am
Keywords: میانگین دوز مرگبار; Influenza; Virus; Neuraminidase; Inhibitor; Pharmacokinetics; Molecular modeling; BQLKEXSYWRBWQK-AFMQGRBTSA-N; AUC; area under the concentration-versus-time curve; CC50; 50% cytotoxicity concentration; CL; clearance; CPE; cytopathic effect; D; distributio
Keywords: میانگین دوز مرگبار; Biotoxin; Bioterrorism; Biological warfare agent; BW; Biological warfare; CW; chemical weapons; BWAs; Biological warfare agents; BoNTs; Clostridium botulinum neurotoxins; LD50; median lethal dose; PBT; pentavalent botulinum toxoid; SEB; Staphylococus aure
Keywords: میانگین دوز مرگبار; AHR; aryl hydrocarbon receptor; AHR-KO; aryl hydrocarbon receptor knockout; Ahrr; aryl hydrocarbon receptor repressor; AIP; aryl hydrocarbon receptor interacting protein; ALB; serum albumin; ALP; alkaline phosphatase; ALT; alanine aminotransferase; ARNT;
Keywords: میانگین دوز مرگبار; Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM
Cloning, characterization, antibacterial activity and expression of hamp in pond loach (Misgurnus anguillicaudatus) after bacterial challenge with Aeromonas hydrophila
Keywords: میانگین دوز مرگبار; Hepcidin; hamp1; Antimicrobial peptides; Gene expression; M. anguillicaudatus; A. hydrophila; AMP; Antimicrobial peptide; qRT-PCR; Quantitative Polymerase Chain Reaction; aa; amino acid; pI; Theoretical isoelectric point; EC; Extinction coefficient; II; I
Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract
Keywords: میانگین دوز مرگبار; V; Volume; NaCl; Sodium chloride; HCl; Hydrochloric acid; mm; millimeter; LD50; median lethal dose; Hertia cheirifolia; Anti-inflammatory; Gastroprotective; Liquid chromatography;
Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity
Keywords: میانگین دوز مرگبار; Artemisia herba-alba Asso.; Essential oil; Antibacterial activity; Median lethal dose; Camphor;
Betulinic, oleanolic and ursolic acids inhibit the enzymatic and biological effects induced by a P-I snake venom metalloproteinase
Keywords: میانگین دوز مرگبار; Local tissue damage; Metalloproteinase; Molecular docking; Snake venom; Triterpenic acids; BA; betulinic acid; CK-NAC; creatine kinase activated by N-acetyl cysteine; CM-Sephadex; carboxymethyl sephadex; IC50; half maximal inhibitory concentration; i.p.;
Anti-scorpion venom activity of Thapsia garganica methanolic extract: Histopathological and biochemical evidences
Keywords: میانگین دوز مرگبار; B. occitanus; Buthus occitanus; LD50; Median lethal dose; LD99; Lethal Dose 99; IC 50; Concentration of 50% inhibition; LDH; Lactate deshydrogenase; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; CPK; Créatine phosphokinase; T. garganica
Effects of a new antiprotozoal drug, N,Nâ²-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria
Keywords: میانگین دوز مرگبار; Liver mitochondria; Mitochondrial swelling; Amidine derivatives; Methoxyamidine; Respiratory chain enzymes; ATPase activity; ÎÏm; mitochondrial transmembrane potential; A; absorbance; ADP; adenosine diphosphate; AIDS; acquired immunodeficiency syndrome;
Ameliorating effects of Nigella sativa oil on aggravation of inflammation, oxidative stress and cytotoxicity induced by smokeless tobacco extract in an allergic asthma model in Wistar rats
Keywords: میانگین دوز مرگبار; AHR; airway hyperresponsiveness; b.w.; body weight; BALF; BronchoAlveolar Lavage Fluid; CAT; catalase; DGRSDT; (in Frensh Direction Générale de la Recherche Scientifique et du Développement Technologique) General Directorate for Scientific Research and
Development of a new approach of immunotherapy against scorpion envenoming: Avian IgYs an alternative to equine IgGs
Keywords: میانگین دوز مرگبار; Aah; Androctonus australis hector; ED50; median effective dose; FCA; Freund's complete adjuvant; FIA; Freund's incomplete adjuvant; Fab; Fragment antigen binding; IgY; yolk immunoglobulin; IgG; Immunoglobulin G; LD50; median lethal dose; NMRI; Naval Medic
Regulated delayed attenuation enhances the immunogenicity and protection provided by recombinant Salmonella enterica serovar Typhimurium vaccines expressing serovar Choleraesuis O-polysaccharides
Keywords: میانگین دوز مرگبار; Regulated delayed attenuation; Recombinant vaccines; S. Typhimurium; S. Choleraesuis; O-polysaccharide; Protection; OPS; O-polysaccharides; NTS; non-typhoidal Salmonella; S. Typhimurium; Salmonella enterica serovar Typhimurium; LPS; lipopolysaccharides; C
Dioscorea zingiberensis C. H. Wright: An overview on its traditional use, phytochemistry, pharmacology, clinical applications, quality control, and toxicity
Keywords: میانگین دوز مرگبار; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CK; creatine kinase; CNKI; China Knowledge Resource Integrated; CT; clotting time; CVD; cardiovascular disease; D. zingiberensis; Dioscorea zingiberensis C. H. Wright; ELSD; evaporative light
Nanoencapsulated Thymus capitatus essential oil as natural preservative
Keywords: میانگین دوز مرگبار; EO; essential oil; DPPH; 1,1-diphenyl-2-picrylhydrazyl; GC-MS; Gas Chromatography-Mass Spectrometry; IC50; concentration inhibiting 50% of the observed effect; IZ; inhibition zone diameter; LD50; median lethal dose; L.R.I.; Linear Retention Index; MIC
Anti-Deinagkistrodon acutus venom properties of ethanolic root extract from Cynanchum paniculatum (Bunge) kitag and its GC-MS analysis
Keywords: میانگین دوز مرگبار; CK; creatine kinase; CPER; ethanolic root extract of C. paniculatum; DAV; Deinagkistrodon acutus venom; ED50; effective dose 50; GC-MS; gas chromatography-mass spectrometry; i.m.; intra-muscularly; i.p.; intraperitoneally; i. pl.; intraplantarly; LD50;
Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses
Keywords: میانگین دوز مرگبار; Acylguanidine; Zanamivir; Oseltamivir; Neuraminidase inhibitor; Influenza; Arg; arginine; Boc; tert-butoxycarbonyl; (Boc)2O; di(tert-butyl) dicarbonate; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DIEA; diisopropyl ethylamine; D
A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine
Keywords: میانگین دوز مرگبار; Aconitum carmichaeli Debx.; Aconitum alkaloids; Pharmacokinetics; Herb-drug interactions; Toxicology; Personalized medicine; DMEs; drug-metabolizing enzymes; ETs; efflux transporters; BB; bioavailability barrier; DDAs; diester-diterpene alkaloids; MDAs; m
Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review
Keywords: میانگین دوز مرگبار; AD; Alzheimer's disease; AcOEt; Ethyl acetate; AOE; Ethanolic extract of the fruit of A. oxyphylla; AOF; Alpinia oxyphylla fruit; BBB; Blood-brain barrier; CAT; Catalase; CCl4; Carbon tetrachloride; CKD; Chronic kidney disease; EA portion; Ethyl acetate-s
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review
Keywords: میانگین دوز مرگبار; Qinjiao; Phytochemical; Pharmacology; Pharmacokinetic; Quality control; Authentication; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under curve; 6-BA; 6-benzylaminopurine; CCl4; carbon tetrachloride; Cl; clearance; Cmax; conc
Comparison of the acute inhibitory effects of Tetrodotoxin (TTX) in rat and human neuronal networks for risk assessment purposes
Keywords: میانگین دوز مرگبار; ARfD; acute reference dose; DIV; days in vitro; EFSA; European Food Safety Authority; FBS; fetal bovine serum; hIPSC; human-induced pluripotent stem cell; IC50; half maximal inhibitory concentration; LD50; median lethal dose; LOEAL; lowest observed advers
Mass spectral characterization of tabun-labeled lysine biomarkers in albumin
Keywords: میانگین دوز مرگبار; AChE; acetylcholinesterase; u; unified atomic mass unit; hAChE; human AChE; HCD; high-energy collision-induced dissociation; HPLC; high performance liquid chromatography; LD50; median lethal dose; MS/MS; tandem mass spectrometry fragmentation; MWCO; molec
Antifungal activity of the essential oil obtained from Cryptocarya alba against infection in honey bees by Nosema ceranae
Keywords: میانگین دوز مرگبار; GC-MS; gas chromatography-mass spectrometry; EO; essential oil; INDAP; Instituto de Desarrollo Agropecuario; SAG; Servicio AgrÃcola y Ganadero; OECD; Organization for Economic Co-operation and Development; OIE; Office International des Epizooties; LD50
The toxicity and the acaricidal mechanism against Psoroptes cuniculi of the methanol extract of Adonis coerulea Maxim
Keywords: میانگین دوز مرگبار; AChE; Acetylcholinesterase; CAT; Catalase; CLL model; The complementary log-log model; GST; Glutathione-S-transferase; HPLC; High performance liquid chromatography; IC50; : 50% inhibitory concentration; LD50; Median lethal dose; MDA; Malonyldialdehyde;
The new algorithm for calculation of median lethal dose (LD50) and effective dose fifty (ED50) of Micrarus fulvius venom and anti-venom in mice
Keywords: میانگین دوز مرگبار; Effective dose; Median lethal dose; Snake venom; Snake anti venom; Mice; Micrarus fulvius;
Chimpanzee adenovirus vector-based avian influenza vaccine completely protects mice against lethal challenge of H5N1
Keywords: میانگین دوز مرگبار; HPAI; highly pathogenic avian influenza; RDE; receptor destroying enzyme; AdHu5; human adenovirus serotype 5; HA; haemagglutinin; AdC7; chimpanzee adenovirus serotype 24; LD50; median lethal dose; Influenza; H5N1; AdC7; Vaccine; Immune responses;
Is sunitinib a Narrow Therapeutic Index Drug? - A systematic review and in vitro toxicology-analysis of Sunitinib vs. Imatinib in cells from different tissues
Keywords: میانگین دوز مرگبار; Apoptosis; Drug safety; Imatinib; Narrow Therapeutic Index Drug (NTID); Receptor tyrosine kinase (RTK); Sunitinib; Toxicity; Tyrosine kinase inhibitor (TKI); Cell viability; ALL; acute lymphoblastic leukemia; AUC; area under the curve; b.i.d.; twice daily
Toxicological evaluation of advanced glycation end product Nε-(carboxymethyl)lysine: Acute and subacute oral toxicity studies
Keywords: میانگین دوز مرگبار; Nε-(carboxymethyl)lysine; Oral acute toxicity; Subacute toxicity; Oxidative stress; Mice; CML; Nε-(carboxymethyl)lysine; AGEs; advanced glycation endproducts; OECD; Organization for Economic Co-operation and Development; LD50; median lethal dose; RBC; r
Sperm quality and fertility in rats after prenatal exposure to low doses of TCDD: A three-generation study
Keywords: میانگین دوز مرگبار; TCDD; Tetrachlorodibenzo-p-dioxin; GD; gestational day; LOAEL; lowest observed adverse effect level; LD50; median lethal dose; PND; post-natal day; Dioxin; Epididymis; Sperm quality; Fertility; Transgenerational effect;
VX toxicity in the Göttingen minipig
Keywords: میانگین دوز مرگبار; Nerve agent; Swine; Göttingen minipig; Median lethal dose; Age; Actigraphy;
Acute and sub-chronic toxicity of glucose-cysteine Maillard reaction products in Sprague-Dawley rats
Keywords: میانگین دوز مرگبار; AGEs; advanced glycation end-products; ALB; albumin; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BUN; blood urea nitrogen; CRE; creatinine; FDA; the USA Food and Drug Administration; GLU; glucose; HMF; 5-Hydroxymethyl-2-furfural; LD50;
The molecular mechanisms of sodium metabisulfite on the expression of KATP and L-Ca2+ channels in rat hearts
Keywords: میانگین دوز مرگبار; CA; chromosomal aberrations; Ct; threshold cycle; EC; excitation-contraction; FASEB; Federation of American Societies for Experimental Biology; HE; hematoxylin-eosin; KATP; ATP-sensitive K+; Kir6.x; inward-rectifying K+ channel family; L-Ca2+; L-type
Toxicological evaluation of ferrous N-carbamylglycinate chelate: Acute, Sub-acute toxicity and mutagenicity
Keywords: میانگین دوز مرگبار; Iron amino acid chelates; Ferrous N-carbamylglycinate; Acute toxicity; Sub-acute toxicity; Mutagenicity; MMS; Methyl methyl sulfonate; CP; cyclophosphamide; SD; Sprague-Dawley; BMM; bone marrow micronucleus; LD50; median lethal dose; ANOVA; one-way anal
Proof of concept for a banding scheme to support risk assessments related to multi-product biologics manufacturing
Keywords: میانگین دوز مرگبار; Biologics; Manufacturing; Cross-contamination; Cleaning validation; Impurities; Risk assessment; ADE; acceptable daily exposure; API; active pharmaceutical ingredient; FDA; Food and Drug Administration; G-CSF; granulocyte colony stimulating factor; GM-CSF
Nauclea latifolia Smith (Rubiaceae) exerts antinociceptive effects in neuropathic pain induced by chronic constriction injury of the sciatic nerve
Keywords: میانگین دوز مرگبار; ANOVA; analysis of variance; ATCC; American type culture collection; AUC; areas under the curve; CCI; chronic constriction injury; CHO; Chinese hamster ovary; EC50; the 50% effective concentration; F1; fractions; HPLC; high-performance liquid chromatograp