Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Cochlea; Immunity; Macrophage; Inflammation; TLR; Toll-like receptor; RIG-I; Retinoic acid inducible gene-I; MDA5; Melanoma differentiation-associated gene 5; TGF-β; Transforming growth factor beta; MHC-II; major histocompatibility complex II; ICAM-1; In
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Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Interstitial lung disease; Myositis; Heterogeneity; antiaminoacyl-tRNA synthetase; melanoma differentiation-associated gene 5;
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; ÎÏ; mitochondrial membrane potential; Bcl-2; B-cell CLL/lymphoma 2; BH; Bcl-2 homology; CJ; crista junction; CM; cristae membrane; Erv1; essential for respiration and viability; ETC; electron transport chain; FAD; flavin adenine dinucleotide; FADH2; fla
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Clarithromycin (PubChem CID: 84029); poly I:C (PubChem CID: 32744); Pam3CSK4 (PubChem CID: 130704); CAM; clarithromycin; CARD; caspase activation and recruitment domain; CCL5; chemokine (C-C motif) ligand 5; CF; cystic fibrosis; COPD; chronic obstructive
The role of type I interferons in innate and adaptive immunity against viruses in Atlantic salmon
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Adjuvant; DNA vaccine; Fish; IFN; ISG; TLR; CRFB; class II cytokine receptor family member; HE; hemagglutininesterase; IFN; interferon; IFN-I; type I IFN; IFNAR; mammalian type I IFN receptor; IPNV; infectious pancreatic necrosis virus; IPS-1; interferon
Rig-I is involved in inflammation through the IPS-1/TRAF6 pathway in astrocytes under chemical hypoxia
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; RIG-I; retinoic acid-inducible gene I; IPS-1; interferon-β promoter stimulator-1; TRAF; TNF receptor-associated factor; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NLRs; NOD-like receptors; RLRs; RIG-like receptors; MDA5; melanoma dif
Identification of a novel porcine OASL variant exhibiting antiviral activity
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; JEV; Japanese encephalitis virus; IFNs; interferons; ISGs; IFN-stimulated genes; OAS; 2',5'-oligoadenylate synthetase; PRRs; pattern-recognition receptors; RNase L; ribonuclease L; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-
Innate immunity related pathogen recognition receptors and chronic hepatitis B infection
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; acLDL; acylated LDL; AIM2; absent in melanoma 2; AP-1; activator protein 1; BDCA-2; blood DC antigen; BEC; biliary epithelial cells; CARD; caspase recruitment and activation domains; cDC; common dendritic cells; CL-L1; collectin liver 1; CL-K1; collectin
Zebrafish STAT6 negatively regulates IFNÏ1 production by attenuating the kinase activity of TANK-binding kinase 1
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r
Comparative transcriptome analyses indicate enhanced cellular protection against FMDV in PK15 cells pretreated with IFN-γ
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; IFN-γ; Interferon gamma; FMDV; Foot and mouth disease virus; ISGs; IFN-stimulated genes; FMD; Foot-and-mouth disease; DGE; Digital gene expression; FDR; False discovery rate; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; qRT-PCR; Quan
Identification and characterization of the melanoma differentiation - associated gene 5 in sea perch, Lateolabrax japonicus
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Melanoma differentiation-associated gene 5; Sea perch; Nervous necrosis virus; Innate immune;
Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Dermatomyositis; Interstitial lung disease; Cytokine; Chemokine CX3CL1; Ab; antibody; ADM; amyopathic dermatomyositis; CT; computed tomography; CX3CL1; chemokine (C-X3-C motif) ligand 1; EGF; epidermal growth factor; FGF-2; fibroblast growth factors-2; Fl
Research ArticleMDA5 plays a critical role in interferon response during hepatitis C virus infection
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; HCV; hepatitis C virus; RIG-I; retinoic acid inducible gene I; MDA5; melanoma differentiation-associated gene 5; IFN; interferon; UTR; untranslated region; MAVS; mitochondrial antiviral signaling protein; PAMP; pathogen-associated molecular patterns; HCVc
Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; MAVS variants; Negative regulator; Interferon; IRF7; Zebrafish; CARD; caspase recruiting domain; CPE; cytopathic effect; DBD; DNA binding domain; EPC; epithelioma papulosum cyprini; GBP4; guanylate binding protein 4; IFN; interferon; IKKε; IkappaB kinase
Dermatomyositis, polymyositis and immune-mediated necrotising myopathies
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; BAFF; B cell-activating factor; BLTK; B lymphoid tyrosine kinase; CCL21; chemokine (C-C motif) ligand 2; CK; creatine kinase; DC; dendritic cell; CTD; connective tissue disease; DFS70; dense fine speckled 70; DM; dermatomyositis; HIV; human immunodeficien
Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; MAVS; mitochondrial antiviral signaling gene; IFN; type I interferon; SNPs; single nucleotide polymorphisms; CDS; coding region; UTR; untranslated region; PRRs; pathogen recognition receptors; PAMPs; pathogen-associated molecular patterns; TLRs; toll-like
An anti-interferon activity shared by paramyxovirus C proteins: Inhibition of Toll-like receptor 7/9-dependent alpha interferon induction
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; IFN; interferon; PIVs; parainfluenza viruses; MeV; measles virus; NiV; Nipah virus; ORF; open reading frame; SeV; Sendai virus; ISGs; IFN-stimulated genes; ds; double stranded; PKR; protein kinase R; PAMPs; pathogen-associated molecular patterns; IRF; int
ISG54 and ISG56 are induced by TLR3 signaling in U373MG human astrocytoma cells: Possible involvement in CXCL10 expression
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; DAMPs; danger-associated molecular patterns; IFN; interferon; ISG; interferon-stimulated gene; MDA5; melanoma differentiation-associated gene 5; PAMPs; pathogen-associated molecular patterns; poly IC; polyinosinic-polycytidylic acid; PRRs; pattern recogni
Viral infections in asthma and COPD
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; RSV; respiratory syncytial virus; HRV; human rhinovirus; LAI; lower airway infection; AHR; airway hyperresponsiveness; TLR3; Toll-like receptor 3; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-associated gene 5; TRIF; Toll/IL-1R do
Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; BiFC; bimolecular fluorescence complementation; CARD; caspase activation and recruitment domain; cGAMP; cyclic GMP-AMP; cGAS; cyclic GMP-AMP synthase; DC; dendritic cell; DUB; deubiquitinase; hSTING; human STING; IFN; interferon; IRF-3; interferon regulat
Activation of Toll-like receptor 3 induces apoptosis of oral squamous carcinoma cells in vitro and in vivo
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; TLR3; Toll-like receptor 3; dsRNA; double-stranded RNA; OSCC; oral squamous cell carcinoma; poly I:C; dsRNA-polyinosinic-polycytidilic acid; IFN-β; interferon-β; PRR; pattern recognition receptors; DCs; dendritic cells; siRNA; small interfering RNA; TUN
Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; ROS; reactive oxygen species; T1D; type 1 diabetes; NOD; nonobese diabetic; BM-MÏ; bone marrow-derived macrophages; MHC; major histocompatibility complex; NOX; NADPH oxidase; Ncf1; neutrophil cytosolic factor 1; TLR; Toll-like receptor; poly(I:C); polyin
Transcriptional regulation of type I interferon gene expression by interferon regulatory factor-3 in Japanese flounder, Paralichthys olivaceus
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; ATF2; activating transcription factor 2; BAC; bacterial artificial clone; CpG-ODN; cytosine-phosphate-guanosine oligodeoxynucleotides; dsRNA; double-strand RNA; IFN; interferon; IKKε; IκB kinase epsilon; IPS-1/MAVS/VISA/Cardif; IFN-β promoter stimulato
Toll-like receptors and macrophage activation in atherosclerosis
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; TLR; Toll-like receptor; PAMP; Pathogen associated molecular pattern; LDL; Low density lipoprotein; SMC; Smooth muscle cell; VCAM-1; Vascular cell adhesion molecule-1; M-CSF; Macrophage colony stimulating factor; TCFA; Thin-cap fibroatheroma; MMP; Matrix
Exogenous IFN-β has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus
Keywords: ژن 5 مرتبط با تمایز ملانوم 5; Innate immunity; picornaviridae infections; type I interferons; asthma exacerbation; BEC; Bronchial epithelial cell; IP-10; Interferon-inducible protein 10; IRF-7; Interferon regulatory factor 7; MDA-5; Melanoma differentiation-associated gene 5; PBEC; Pr