دانلود مقالات ISI درباره Melas + ترجمه فارسی

Inherited leukoencephalopathies with clinical onset in middle and old age

Keywords: ADLD; Adult onset autosomal dominant leukodystrophy; CADASIL; Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; CARASIL; Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

Keywords: AMPK; AMP-activated protein kinase; CaMKs; calmodulin-dependent protein kinases; CPEO; chronic progressive external ophthalmoplegia; CREB; cAMP-responsive element-binding protein; FOXO; forkhead box O transcription factor; G6PD; glucose 6-phosphate dehydr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

A novel mitochondrial mutation m.8989G>C associated with neuropathy, ataxia, retinitis pigmentosa - The NARP syndrome

Keywords: ffERG; full-field electroretinogram; LHON; Leber's hereditary optic neuropathy; MELAS; mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes; MERRF; myoclonic epilepsy with ragged red fibers; MID; mitochondrial disorders; mtDNA; mitoc

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients

Keywords: ASL; arterial spin labeling; A3243G; A-to-G transition at nucleotide position 3243; CBF; cerebral blood flow; DWIs; diffusion-weighted images; FLAIR; fluid-attenuated inversion recovery; MRI; magnetic resonance imaging; mtDNA; mitochondrial DNA; MELAS; mi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

A new mutation in MT-ND1 m.3928G>C p.V208L causes Leigh disease with infantile spasms

Keywords: EEG; electroencephalogram; PAGE; polyacrylamide gel electrophoresis; mtDNA; mitochondrial DNA; LHON; Leber hereditary optic neuropathy; MELAS; mitochondrial encephalomyopathy with lactic acidosis and stroke like episodes; HRM; high resolution melt; PCR; p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of TNF-α in mitochondrial diseases caused by mutations in mtDNA: evidence for signaling through its receptors on mitochondria

Keywords: COX; Cytochrome c oxidase; CPEO; Chronic progressive external ophthalmoplegia; MD; Mitochondrial disease; MELAS; Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes; MERRF; Myoclonic epilepsy with ragged red fibers; OXPHOS; Oxida

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Localization of exogenous DNA to mitochondria in skeletal muscle following hydrodynamic limb vein injection

Keywords: Ch; channel; CLSM; confocal laser scanning microscopy; COX; cytochrome c oxidase; DAPI; 4′, 6-Diamidino-2-phenylindole; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; FISH; fluorescent in situ hybridization; GAPDH; Glyceraldehyde 3-phosphat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cardiomyopathies due to homoplasmic mitochondrial tRNA mutations: morphologic and molecular features

Keywords: mt-tRNAIle; mitochondrial isoleucine tRNA; mtDNA; mitochondrial DNA; HCM; hypertrophic cardiomyopathy; MELAS; mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes; mt-tRNALeu(UUR); mitochondrial leucine (UUR) tRNA; COX; cytochrome c oxid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes

Keywords: CI; complex I; CIII; complex III; CIV; complex IV; CV; complex V; DB; decyl-benzoquinone; D-loop; displacement loop; HIF1α; hypoxia inducible factor 1α; LDH; lactate dehydrogenase; LHON; Leber's hereditary optic neuropathy; LS; Leigh syndrome; MELAS; mi

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Unusual exocrine complication of pancreatitis in mitochondrial disease

Keywords: Mitochondrial disease; Pancreatitis; CPEO; MELAS

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS

Keywords: Cerebral blood flow; MELAS; TCCS; SPECT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

In vivo functional brain imaging and a therapeutic trial of l-arginine in MELAS patients

Keywords: MELAS; Functional brain imaging; PET; MRI; l-arginine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Adult-onset of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) Syndrome Presenting as Acute Meningoencephalitis: A Case Report

Keywords: MELAS; epilepsy; mitochondrial disease; meningoencephalitis; valproic acid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Case reportMELAS-like encephalomyopathy caused by a new pathogenic mutation in the mitochondrial DNA encoded cytochrome c oxidase subunit I

Keywords: mtDNA; Mutation; MELAS; Cytochrome c oxidase; COX; Ragged-red fibers; SDH; Stroke-like episode; MTCOI; Mitochondrial disorder; Respiratory chain;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular investigations of mitochondrial deletions: Evaluating the usefulness of different genetic tests

Keywords: MELAS; mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes; MLPA; multiplex ligation-dependent probe amplification; MNGIE; mitochondrial neurogastrointestinal encephalopathy; RRF; ragged red fibers; mtDNA deletions; MLPA; Mito

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Blastocyst preimplantation genetic diagnosis (PGD) of a mitochondrial DNA disorder

Keywords: Mitochondrial DNA; MELAS; preimplantation genetic diagnosis; mutation load

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Decreased hippocampal expression of calbindin D28K and cognitive impairment in MELAS

Keywords: Mitochondria; MELAS; Cognitive dysfunction; Calbindin; Hippocampus; Calcium-binding protein; Mitochondrial DNA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

MELAS: A nationwide prospective cohort study of 96 patients in Japan

Keywords: JMDRS, Japanese mitochondrial disease rating scale; NPMDS, Newcastle pediatric mitochondrial disease scale; NMDAS, Newcastle mitochondrial disease adult scalePrevalence; MELAS; Cohort study; Natural course; Survival curve; Severity of disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Mitochondrial tRNA valine as a recurrent target for mutations involved in mitochondrial cardiomyopathies

Keywords: MD; mitochondrial disease; mtDNA; mitochondrial DNA; tRNA; transfer ribonucleic acid; MCM; mitochondrial cardiomyopathy; MELAS; mitochondrial encephalopathy, lactic acidosis and stroke-like episodes; MiMyCa; maternally inherited myopathy and cardiomyopath

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Prognosis of symptomatic patients with the A3243G mutation of mitochondrial DNA

Keywords: A3243G mutation; MELAS; mitochondrial disease; mitochondrial DNA; prognosis; seizures; Taiwanese

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The effects of idebenone on mitochondrial bioenergetics

Keywords: CRC; calcium retention capacity; Cs; cyclosporin; DMEM; Dulbecco's modified Eagle's medium; Δψm; mitochondrial membrane potential difference; DTT; dithiothreitol; FCCP; carbonylcyanide-p-trifluoromethoxyphenyl hydrazone; LHON; Leber's hereditary optic n

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

LHON/MELAS overlap mutation in ND1 subunit of mitochondrial complex I affects ubiquinone binding as revealed by modeling in Escherichia coli NDH-1

Keywords: d-NADH; deamino-NADH; DB; decylubiquinone; HAR; hexaammineruthenium; LHON; Leber hereditary optic neuropathy; MELAS; mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome; mtDNA; mitochondrial DNA; NDH-1; bacterial prot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of a mutation in LARS as a novel cause of infantile hepatopathy

Keywords: SNP; single nucleotide polymorphism; PDB; protein data-bank; siRNA; small-interfering ribonucleic acid; LARS; gene encoding the cytoplasmic leucyl-tRNA synthetase; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; LeuRS; leucyl-tRNA syn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Spectrum of neurological and survival outcomes in pyruvate dehydrogenase complex (PDC) deficiency: Lack of correlation with genotype

Keywords: CIDEM; Center for Inherited Disorders of Energy Metabolism; CQ; cognitive quotient; DCA; dichloroacetate; MELAS; mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes; PDC; pyruvate dehydrogenase complex; TPP; thiamine pyrophosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Maintenance of mitochondrial genome distribution by mitochondrial AAA+ protein ClpX

Keywords: mtDNA; mitochondrial DNA; AAA+; ATPase associated with various cellular activities; RNAi; RNA interference; TFAM; mitochondrial transcription factor A; MELAS; mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes; OPA1; optic atrop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Radiolabeled Cu-ATSM as a novel indicator of overreduced intracellular state due to mitochondrial dysfunction: studies with mitochondrial DNA-less ρ0 cells and cybrids carrying MELAS mitochondrial DNA mutation

Keywords: Cu-ATSM, Cu-diacetyl-bis (N4-methylthiosemicarbazone); MELAS, mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes; mtDNA, mitochondrial DNA; PET, positron emission tomographyCu-ATSM; MELAS; Mitochondrial dysfunction; Overreduc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Metabolomic profiling rationalized pyruvate efficacy in cybrid cells harboring MELAS mitochondrial DNA mutations

Keywords: MELAS; Pyruvate; Cybrid; Energy metabolism; Metabolome; CE-MS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Hypersensitivity of A8344G MERRF mutated cybrid cells to staurosporine-induced cell death is mediated by calcium-dependent activation of calpains

Keywords: CPEO; Chronic Progressive External Ophthalmoplegia; KSS; Kearns-Sayre Syndrome; LHON; Leber's Hereditary Optic Neuropathy; MELAS; Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-like episodes; MERRF; Myoclonic Epilepsy with Ragged Red Fibers;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Initial experience in the treatment of inherited mitochondrial disease with EPI-743

Keywords: ARE; antioxidant response element; BSO; l-buthionine-(S,R)-sulfoximine; FRDA; Friedreich ataxia; HMPAO; technetium-99m-hexamethylpropyleneamine oxime; KSS; Kearns-Sayre syndrome; LHON; Leber hereditary optic neuropathy; LS; Leigh syndrome; MELAS; Mitoch

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Mitochondrial disease – a review

Keywords: Alpers; Barth syndrome; heteroplasmy; Kearns–Sayre syndrome; Leigh syndrome; MELAS; mitochondrial disease; MERRF; NARP; Pearson syndrome; PEO

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

CMR gives clue to “ragged red fibers” in the heart in a patient with mitochondrial myopathy

Keywords: MELAS; Ragged red fibers; Cardiovascular magnetic resonance (CMR); Late gadolinium enhancement (LGE)

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Mutation in the mitochondrial tRNAVal causes mitochondrial encephalopathy, lactic acidosis and stroke-like episodes

Keywords: MELAS; mitochondrial encephalopathy, lactic-acidosis and stroke-like episodes; MNGIE; mitochondrial neurogastrointestinal encephalopathy; MTTV; mitochondrial tRNAVal; mtDNA; mitochondrial DNA; DNP; dinitrophenol; Mitochondrial DNA; Mitochondrial disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

New mitochondrial tRNAHIS mutation in a family with lactic acidosis and stroke-like episodes (MELAS)

Keywords: Mitochondria; mt-tRNAHis; MELAS; mt-translation; Cybrids

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Peptides from aminoacyl-tRNA synthetases can cure the defects due to mutations in mt tRNA genes

Keywords: aaRS; aminoacyl-tRNA synthetase(s); bp; base-pair; MELAS; Mitochondrial Encephalomyophathy, Lactic Acidosis, and Stroke-like episodes; mt; mitochondrial; nt; nucleotide; rho+; mt DNA wild-type; WT; wild-type; Mitochondrial diseases; tRNAs; mt mutations;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Mitochondrial DNA damage in spinal and bulbar muscular atrophy patients and carriers

Keywords: poly-Q; Poly-glutamine; SBMA; Spinal and bulbar muscular atrophy; AR; Androgen receptor; SCA1; Spinocerebellar atrophy 1; HD; Huntington's disease; PGC-1α; Peroxisome proliferator activated receptor-γ coactivator-1α; ROS; Reactive oxygen species; SOD2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Detection of eight frequently encountered point mutations in mitochondria in Chinese patients suggestive of mitochondrial encephalomyopathies

Keywords: Mitochondrial encephalomyopathy; Mitochondrial DNA; Mutation; MELAS

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Clinical features of mitochondrial DNA m.3243A>G mutation in 47 Chinese families

Keywords: Mitochondrion; m.3243A>G mutation; MELAS; Urine; Family; China

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Hereditary and non-hereditary microangiopathies in the young. An up-date

Keywords: Cerebral small vessel disease; Cerebral microangiopathy; Hereditary small vessel disease; CADASIL; CARASIL; MELAS; AD-RVLC; PADMAL; HEMID; FABRY; COL4A1; SVBD; Susac's syndrome; Posterior reversible encephalopathy

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

The investigation and diagnosis of pathogenic mitochondrial DNA mutations in human urothelial cells

Keywords: Mitochondrial DNA (mtDNA); Heteroplasmy; MELAS; Urothelial cells; mtDNA rearrangements; Non-invasive diagnosis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of the mitochondrial protein quality control system and actin cytoskeletal alterations in cells harbouring the MELAS mitochondrial DNA mutation

Keywords: MELAS; Mitochondria; Proteome; 2D DIGE; Lon protease; Actin cytoskeleton

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images

Keywords: MELAS; MR spectroscopy (MRS); Lactate; Continuous arterial spin labeling (CASL); Perfusion

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Extensive screening system using suspension array technology to detect mitochondrial DNA point mutations

Keywords: mtDNA; Pathological mutation; Mitochondria; MELAS; Suspension array

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Atteinte rétinienne et myopathies génétiques

Keywords: Rétinite pigmentaire; Dystrophie maculaire réticulaire; Maladie de Coats; Syndrome de Kearn et Sayre; MELAS; MIDD; Dystrophie musculaire facio-scapulo-humérale; Retinitis pigmentosa; Pattern retinal dystrophy; Coats disease; Kearn Sayre Syndrome; MELAS

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

The Neuro-ophthalmology of Mitochondrial Disease

Keywords: chronic progressive external ophthalmoplegia; dominant optic atrophy; Kearns-Sayre syndrome; Leber hereditary optic neuropathy; MELAS; mitochondria; NARP; neuro-ophthalmology; pigmentary retinopathy

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2010 سفارش ترجمه

La l-arginine, une thérapeutique symptomatique efficace au cours d'un syndrome MELAS

Keywords: MELAS; l-arginine; Mitochondriopathie; Épisodes pseudovasculaires; MELAS; l-arginine; Mitochondriopathy; Stroke-like episodes;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

The study of mitochondrial A3243G mutation in different samples

Keywords: A3243G; MELAS; Mitochondrion; Mutation; Urine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

PET imaging of redox and energy states in stroke-like episodes of MELAS

Keywords: MELAS; Stroke-like episodes; Oxidative stress; Over-reduction state; PET; Functional imaging

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Coma arrefléxico en el síndrome de MELAS

Keywords: MELAS; Miopatía mitocondrial; Fibras rojas rasgadas; Acidosis láctica; Coma; MELAS; Mitochondrial myopathy; Ragged-red fibers; Lactic acidosis; Coma;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Accumulation of oxidative stress around the stroke-like lesions of MELAS patients

Keywords: MELAS; Stroke-like episode; Oxidative stress; Edaravone; 8-hydroxy-2′-deoxyguanosine; Manganese superoxide dismutase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

The m.3243A>G mtDNA mutation is pathogenic in an in vitro model of the human blood brain barrier

Keywords: Cell culture model; Blood brain barrier; MELAS; Stroke; Endothelial cells; Astrocytes

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه