Keywords: Mass spectrometry; Metallodrugs; Metallomics; Mode of action; Molecular target identification; CZE; capillary zone electrophoresis; ESI; electrospray ionization; FITExP; functional identification of target by expression proteomics; HPLC; high performance
مقالات ISI (ترجمه نشده)
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Keywords: Liquid chromatography-inductively coupled plasma-mass spectrometry; Speciation; Bio-elements; Metalloproteins; Metalloproteomics; Metallodrugs;
Keywords: Nanoparticles; Metallodrugs; Drug carriers; Catalytic activity; Clusters;
Keywords: Tf; transferrin; TfR; transferrin receptor; RR; ribonucleotide reductase; ROS; reactive oxygen species; MT; metallothionein; HO; heme oxygenase-1; Gallium; Iron; Cancer; Infections; Therapeutics; Metallodrugs;
Advances in the design of organometallic anticancer complexes
Keywords: Bioorganometallic chemistry; Metallodrugs; Anticancer;
Mechanochemistry - A green synthetic methodology leading to metallodrugs, metallopharmaceuticals and bio-inspired metal-organic frameworks
Keywords: Mechanochemistry; Green methodology; Metallodrugs; Metallopharmaceuticals; BioMOFs;
Keywords: Antimicrobial Peptides; Bioorganometallic Chemistry; Medicinal Inorganic Chemistry; Metallocenes; Metallodrugs; synthetic Antimicrobial Peptides (synAMP);
Keywords: Cisplatin; Metallodrugs; Bioinorganic chemistry; Medicinal chemistry; Antitumor agents; Platinum; Platinated proteinsa.u., asymmetric unit; Atox-1, a copper chaperone protein; ATP7A, Menkes’ disease protein; ATP7B, Wilson's disease protein; beSOD, superox
Antimicrobial activity of cis-[Ru(bpy)2(L)(Lâ²)]n+ complexes, where Lâ¯=â¯4-(4-chlorobenzoyl)pyridine or 4-(benzoyl)pyridine and Lâ²â¯=â¯Clâ or CO
Keywords: Ruthenium complexes; Nucleobases; Photochemical; Antibacterial drugs; Metallodrugs;
Synthetic investigation of binary-ternary Cr(III)-hydroxycarboxylic acid-aromatic chelator systems. Structure-specific influence on adipogenic biomarkers linked to insulin mimesis
Keywords: Chromium-hydroxycarboxylic acid systems; Synthesis and X-ray structure; Metal-induced adipogenesis; Insulin mimesis; Diabetes mellitus; Metallodrugs;
New zinc(II) N4 tetradentate Schiff base complex: A potential cytotoxic metallodrug and simple precursor for the preparation of ZnO nanoparticles
Keywords: Schiff base; Metallodrugs; Protein interactions; ZnO nanoparticles; Photocatalytic degradation;
Preparation, characterization and evaluation of novel 1,3,5-triaza-7-phosphaadamantane (PTA)-based palladacycles as anti-cancer agents
Keywords: Palladacycles; Metallacycles; DNA binding studies; Anti-cancer agents; Metallodrugs; 1,3,5-Triaza-7-phosphaadamantane complexes;
Improving cytotoxic properties of ferrocenes by incorporation of saturated N-heterocycles
Keywords: Metallodrugs; Ferrocene derivatives; N-heterocycles; Cytotoxicity; Ovarian cancer;
Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes
Keywords: Copper; Bis(thiosemicarbazones); Metallodrugs; Cancer theranostics;
Synthesis, characterization and biological activity of gallium(III) complexes with non-symmetrical N2O-donor Schiff bases
Keywords: Gallium complexes; Metallodrugs; Cancer; A-549; Schiff bases;
Insights into molecular mechanism of action of salan titanium(IV) complex with in vitro and in vivo anticancer activity
Keywords: Cytotoxicity mechanism; Metallodrugs; Cisplatin; In vivo; Cell cycle; Apoptosis;
Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs
Keywords: Metal N-heterocyclic carbene complexes; Anti-tumor; Metallodrugs; Mode of action; Structure-activity relationships;
DNA damage and induction of apoptosis in pancreatic cancer cells by a new dinuclear bis(triazacyclonane) copper complex
Keywords: Copper; Cytotoxicity; DNA damage; Metallodrugs
Selective interaction of Hpn-like protein with nickel, zinc and bismuth in vitro and in cells by FRET
Keywords: FRET; Metal selectivity; Metallodrugs; Metalloproteins; Nickel storage
Antitubercular activity of Ru (II) isoniazid complexes
Keywords: Tuberculosis; Resistant strains; Metal complexes; Metallodrugs; Tetraammine- and pentaammine ruthenium complexes; Isoniazid
Ruthenium(II) complexes with hydroxypyridinecarboxylates: Screening potential metallodrugs against Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; Cytotoxicity; Ruthenium(II) complexes; Metallodrugs; Hydroxypyridinecarboxylates;
Inductively coupled plasma mass spectrometry for metallodrug development: Albumin binding and serum distribution of cytotoxic cis- and trans-isomeric platinum(II) complexes
Keywords: Metallodrugs; ICP–MS; Human serum; Albumin
[Fe(CN)5(isoniazid)]3 −: An iron isoniazid complex with redox behavior implicated in tuberculosis therapy
Keywords: Isoniazid; Metallodrugs; Pentacyanoferrate; Tuberculosis; EPR radical trapping
Advances of CE-ICP-MS in speciation analysis related to metalloproteomics of anticancer drugs
Keywords: BGE, Background electrolyte; CE, Capillary electrophoresis; EOF, Electro osmotic flow; ICP-MS, Inductively coupled plasma mass spectrometryCapillary electrophoresis; ICP-MS; Metallodrugs; Proteins; Mode of action
Hydroxypyridinones as “privileged” chelating structures for the design of medicinal drugs
Keywords: Hydroxypyridinones; 3-Hydroxy-4-pyridinones; Iron chelators; Anti-neurodegeneratives; Metallodrugs; Medicinal chemistry;
Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro
Keywords: Gold compounds; Metallodrugs; Malaria; Falcipain 2
Zinc finger proteins as templates for metal ion exchange: Substitution effects on the C-finger of HIV nucleocapsid NCp7 using M(chelate) species (M = Pt, Pd, Au)
Keywords: NCp7; Mass spectrometry; Protein adducts; Zinc finger; Metallodrugs
Metals in anticancer therapy: Copper(II) complexes as inhibitors of the 20S proteasome
Keywords: Proteasome inhibition; Anticancer therapy; Copper(II); Metallodrugs; Bioinorganic
On the medicinal chemistry of gold complexes as anticancer drugs
Keywords: Gold complexes; Thioredoxin reductase; Metallodrugs; Mitochondria
Cyclic tetranuclear half-sandwich ruthenium(II) complexes with 4,7-phenanthroline and hydroxo bridges: Crystal structure, solution behaviour and binding to nucleosides
Keywords: Cymene; Metallodrugs; Antitumour drugs; Nucleobase; Temperature variable 1H NMR