Cdk1 and BRCA1 target γ-tubulin to microtubule domains
Keywords: ریزلوله یا میکروتوبول; Cdk1; BRCA1; γ-Tubulin; Microtubule; DNA damage response;
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Antibody-DM1 conjugates as cancer therapeutics
Keywords: ریزلوله یا میکروتوبول; Maytansinoid; DM1; Microtubule; Cancer; Tubulin
SAP-like domain in nucleolar spindle associated protein mediates mitotic chromosome loading as well as interphase chromatin interaction
Keywords: ریزلوله یا میکروتوبول; NuSAP; nucleolar spindle associated protein; MT; microtubule; SAP; SAF, Acinus, PIAS; CMV IE; cytomegalovirus immediate early; GST; glutathione S-transferase; eGFP; enhanced green fluorescent protein; FCS; fluorescence correlation spectroscopy; FRAP; fluo
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one induces cell cycle arrest and apoptosis in HeLa cells by preventing microtubule polymerization
Keywords: ریزلوله یا میکروتوبول; ODQ; Tubulin; Microtubule; Cell cycle arrest; Apoptosis
βIII-Tubulin is required for interphase microtubule dynamics in untransformed human mammary epithelial cells
Keywords: ریزلوله یا میکروتوبول; Microtubule; βIII-Tubulin; Tubulin isotype; Mammary epithelial cells; Breast cancer
Dynamic regulation of GEF-H1 localization at microtubules by Par1b/MARK2
Keywords: ریزلوله یا میکروتوبول; Cell polarity; GEF-H1; Microtubule; Par1b/MARK2
Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules
Keywords: ریزلوله یا میکروتوبول; Tubulin; Tubulin-active compound; Microtubule; Microtubule destabilization; Pironetin analogue; Cytotoxicity
Design of self-organizing microtubule networks for molecular communication
Keywords: ریزلوله یا میکروتوبول; Biological computing and communication; Molecular motor; Microtubule; Self organization; Microtubule network
The ins and outs of tubulin acetylation: More than just a post-translational modification?
Keywords: ریزلوله یا میکروتوبول; Acetylation; Tubulin; Microtubule; HDAC6; Signalling; Post-translational modification;
Acetyl analogs of combretastatin A-4: Synthesis and biological studies
Keywords: ریزلوله یا میکروتوبول; Combretastatin A-4; Trimethoxyphenylacetone; Tubulin; Microtubule; Cytotoxicity; Cancer
Microtubule-targeted agents: When mitochondria become essential to chemotherapy
Keywords: ریزلوله یا میکروتوبول; Anticancer drug; Microtubule; Mitochondria; Apoptosis; Pharmacology
Centrosomes, microtubules and neuronal development
Keywords: ریزلوله یا میکروتوبول; Neuronal development; Migration; Differentiation; Neuronal polarization; Neuropsychiatric disease; Centrosome; Acentrosomal microtubule organization; Microtubule
Microtubules are involved in regulating body length in hydra
Keywords: ریزلوله یا میکروتوبول; Body size; Microtubule; Actin; Epithelial cell shape; Hydra
Phosphorylated β-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain
Keywords: ریزلوله یا میکروتوبول; Wnt signaling; Neurogenesis; Cell polarity; Microtubule; Centrosome; Mitotic spindle; Asymmetric cell division; Midbrain;
Role of gamma-synuclein in microtubule regulation
Keywords: ریزلوله یا میکروتوبول; Gamma-synuclein; Cancer; Drug resistance; Paclitaxel; Microtubule
The distribution of β-tubulin isotypes in cultured neurons from embryonic, newborn, and adult mouse brains
Keywords: ریزلوله یا میکروتوبول; Beta-tubulin; Tubulin isotypes; Beta-II; Beta-III; Beta-V; Microtubule;
Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde
Keywords: ریزلوله یا میکروتوبول; Mitotic catastrophe; Spindle assembly; Microtubule; Cell cycle arrest; DNA damage; Therapeutic target; Vanillin derivative
p21Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells
Keywords: ریزلوله یا میکروتوبول; CDKN1A; p21Cip1; Focal adhesion; Microtubule; HDAC6; Mammary epithelial cells; Breast cancer
Macroscopic simulations of microtubule dynamics predict two steady-state processes governing array morphology
Keywords: ریزلوله یا میکروتوبول; Microtubule; Dynamic instability;
Reversible response of protein localization and microtubule organization to nutrient stress during Drosophila early oogenesis
Keywords: ریزلوله یا میکروتوبول; Drosophila oogenesis; Polarized transport; oskar RNP; Starvation response; Microtubule;
Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth
Keywords: ریزلوله یا میکروتوبول; 3-AT; 3-amino-1,2,4-triazole; AD; activation domain; ANOVA; analysis of variance; BD; binding domain; CaMy1; calmyrin1; CIB1; calcium and integrin binding protein 1; DIV; days in vitro; DMEM; Dulbecco's Modified Eagle Medium; FBS; fetal bovine serum; GFP;
Regulation of nucleocytoplasmic trafficking of viral proteins: An integral role in pathogenesis?
Keywords: ریزلوله یا میکروتوبول; BPV; bovine papillomavirus; BRAP2; BRCA1-associated protein 2; CAV; chicken anaemia virus; CBP; CREB binding protein; Cdk; cyclin dependent kinase; CK1; protein kinase CK1; CK2; protein kinase CK2; Crm1; chromosome region maintenance protein 1; CTD; C-ter
The role of the Kinesin-13 family protein TbKif13-2 in flagellar length control of Trypanosoma brucei
Keywords: ریزلوله یا میکروتوبول; Flagellum; Kinesin; Sleeping sickness; Microtubule; Axoneme;
Temperature dependence rigidity of non-taxol stabilized single microtubules
Keywords: ریزلوله یا میکروتوبول; Microtubule; Flexural rigidity; Temperature; Anisotropic property; Conformation change;
Podophyllotoxin analogues active versus Trypanosoma brucei
Keywords: ریزلوله یا میکروتوبول; Sleeping sickness; Trypanosoma brucei; Microtubule
Distinct neuronal localization of microtubule-associated protein 4 in the mammalian brain
Keywords: ریزلوله یا میکروتوبول; MAP; microtubule-associated protein; NGF; nerve growth factor; GFAP; glial fibrillary acidic protein; CA; cornu ammonis; DG; dentate gyrus; MAP4; MAP2; tau; Microtubule; Hippocampus; Cerebellum;
Neurite elongation from Drosophila neural BG2-c6 cells stimulated by 20-hydroxyecdysone
Keywords: ریزلوله یا میکروتوبول; Drosophila; Neurite; Actin; Microtubule;
Nucleotide-dependent behavior of single molecules of cytoplasmic dynein on microtubules in vitro
Keywords: ریزلوله یا میکروتوبول; AMP-PNP; 5â²-adenylylimidodiphosphate; Vi; vanadate; Cytoplasmic dynein; Dynactin; p150; Single molecule; Microtubule;
Stochastic simulation and graphic visualization of mitotic processes
Keywords: ریزلوله یا میکروتوبول; Mitosis; Microtubule; Simulation; Stochastic; Imaging; Yeast;
Mathematical modeling of microtubule dynamics: Insights into physiology and disease
Keywords: ریزلوله یا میکروتوبول; AD, Alzheimer's diseaseCytoskeleton; Kinetics; Microtubule; Model; Tau phosphorylation
Filamentous microtubules in the neuronal spinous process and the role of microtubule regulatory drugs in neuropathic pain
Keywords: ریزلوله یا میکروتوبول; Taxol; Chemotherapy; Microtubule; Pain; Synapse; CNS; Vinca drugs;
Dynamic modulation of cytoskeleton during in vitro maturation in human oocytes
Keywords: ریزلوله یا میکروتوبول; cortical granule; microfilament; microtubule; mitochondria; spindle;
Characterization of gold nanoparticle binding to microtubule filaments
Keywords: ریزلوله یا میکروتوبول; Microtubule; Gold nanowires; Biotemplating; Surface enhanced Raman spectroscopy; X-ray photoelectron spectroscopy
A new method for characterization of thermal properties of human enamel and dentine: Influence of microstructure
Keywords: ریزلوله یا میکروتوبول; Enamel; Dentine; Thermal diffusivity; Thermal conductivity; Microtubule; Infrared thermography
Live-cell analysis of kinetochore-microtubule interaction in budding yeast
Keywords: ریزلوله یا میکروتوبول; Saccharomyces cerevisiae; Chromosome; Kinetochore; Centromere; Spindle; Microtubule; Mitosis; Live cell imaging; Fluorescence microscopy;
The role of formins in human disease
Keywords: ریزلوله یا میکروتوبول; Formin; Actin; Microtubule; Rho GTPase; Non-syndromic deafness; Cancer; Myelodysplasia; Tumor suppression; Premature ovarian failure; Limb deformity; Metastasis; Immune response; Oncosome; Microvesicle
The influence of mediators of intracellular trafficking on transgene expression efficacy of polymer–plasmid DNA complexes
Keywords: ریزلوله یا میکروتوبول; Non-viral gene delivery; Histone deacetylase inhibitors; HDAC; Tubacin; Microtubule; Trichostatin A
Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents
Keywords: ریزلوله یا میکروتوبول; Microtubule; Colchicine; Virtual screening; Molecular docking; Pharmacophore
How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays
Keywords: ریزلوله یا میکروتوبول; Mitosis; Kinesin; Motor; Microtubule; Mitotic spindle
Formins and microtubules
Keywords: ریزلوله یا میکروتوبول; Formin; Microtubule; Microtubule stability; Centrosome
Kinesins to the core: The role of microtubule-based motor proteins in building the mitotic spindle midzone
Keywords: ریزلوله یا میکروتوبول; Mitosis; Cytokinesis; Microtubule; Motor protein; Kinesin
Synthesis and biological evaluation of 2′,5′-dimethoxychalcone derivatives as microtubule-targeted anticancer agents
Keywords: ریزلوله یا میکروتوبول; Synthesis; Claisen–Schmidt condensation; Chalcone; Anticancer; Microtubule; Tubulin polymerization; Paclitaxel; Anti-mitotic
RIP3 and AtKinesin-13A – A novel interaction linking Rho proteins of plants to microtubules
Keywords: ریزلوله یا میکروتوبول; Rho; ROP; Effector; ICR; RIP; Polar growth; AtKinesin-13A; Plant; Microtubule; Cytoskeleton
Polycystin-1 is a microtubule-driven desmosome-associated component in polarized epithelial cells
Keywords: ریزلوله یا میکروتوبول; Polycystin; Cytoskeleton; Microtubule; Intermediate filament; Desmosome
Microtubules govern stress granule mobility and dynamics
Keywords: ریزلوله یا میکروتوبول; RNP; Stress granules; Arsenate; Microtubule; FRAP; PABP;
Olesoxime prevents microtubule-targeting drug neurotoxicity: Selective preservation of EB comets in differentiated neuronal cells
Keywords: ریزلوله یا میکروتوبول; Neuroprotection; Microtubule; EB proteins; Mitochondria; Taxanes; Vinca alkaloids
Chemical target and pathway toxicity mechanisms defined in primary human cell systems
Keywords: ریزلوله یا میکروتوبول; Cell-based assay; Endothelial cell; Epithelial cell; Human; Inflammation; Mechanism of action; Microtubule; Mitochondria; Smooth muscle cell; Toxicity pathway
The immediate large-scale dendritic plasticity of cortical pyramidal neurons subjected to acute epidural compression
Keywords: ریزلوله یا میکروتوبول; compression; microtubule; sensorimotor cortex; taxol; trauma; LY; Lucifer Yellow; MAP2; microtubule associated protein 2; PB; phosphate buffer; PBS; phosphate-buffered saline; PGP; protein gene product;
Formins in development: Orchestrating body plan origami
Keywords: ریزلوله یا میکروتوبول; Formin; Development; Cytoskeleton; Cytokinesis; Polarity; Actin; Microtubule; Actin nucleation; Diaphanous; Daam; Cappuccino; Spire
Biomolecular motors at the intersection of nanotechnology and polymer science
Keywords: ریزلوله یا میکروتوبول; Biopolymer; Hybrid device; Kinesin; Myosin; Microtubule; Actin; Molecular shuttle; Molecular motor; Motor protein; Cyotskeletal filament;