Keywords: MLC، زنجیره سبک میوزین; ESCs, embryonic stem cells; EBs, embryoid bodies; FPP, farnesyl pyrophosphate; GGPP, geranylgeranyl pyrophosphate; MHC, myosin heavy chain; MLC, myosin light chain; ANP, atrium natriuretic peptideStatin; Myogenesis; Transcription; Cholesterol synthesis; S
مقالات ISI MLC، زنجیره سبک میوزین (ترجمه نشده)
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Keywords: MLC، زنجیره سبک میوزین; Ccl K18, caspase cleaved keratin 18; eNOS, endothelial nitric oxide synthase; FE Na, fractional excretion of sodium; KLF-2, Krüppel-like factor 2; LFABP, liver type fatty acid binding protein; MLC, myosin light chain; RPL19, ribosomal protein L19; TNF, tu
Wogonin inhibits LPS-induced vascular permeability via suppressing MLCK/MLC pathway
Keywords: MLC، زنجیره سبک میوزین; Wogonin (PubChem CID: 5281703); Wortmannin (PubChem CID: 312145)LPS, lipopolysaccharide; VEGF, vascular endothelial growth factor; ZO-1, zonula occludens-1; MLCK (MYLK), myosin light chain kinase; MLC, myosin light chain; p-MLCK, phosphorylated myosin lig
Protective effect of 1,25-dihydroxyvitamin D3 on ethanol-induced intestinal barrier injury both in vitro and in vivo
Keywords: MLC، زنجیره سبک میوزین; 1,25(OH)2D3, 1,25-dyhydroxy vitamin D3; TJ, tight junction; ALD, alcoholic liver disease; VDR, vitamin D receptor; TEER, transepithelial electrical resistance; FD-4, FITC-Dextran 4000 Da; MLCK, myosin light chain kinase; MLC, myosin light chain; ROS, reac
P21-activated kinase 4 – Not just one of the PAK
Keywords: MLC، زنجیره سبک میوزین; MRLCs, myosin regulatory light chains; MLC, myosin light chain; NK, natural killer; NES, nuclear export signal; NLS, nuclear localisation signal; CRM-1, chromosome region maintenance-1; UV, ultraviolet; ECM, extracellular matrix; miRNA, microRNA; SH3, Src
Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits
Keywords: MLC، زنجیره سبک میوزین; PKGIα, protein kinase G type Iα; MLC, myosin light chain; MLCP, myosin light chain phosphatase; MLCK, myosin light chain kinase; MYPT1, myosin phosphatase target subunit 1Filtration barrier permeability; Insulin; NAD(P)H oxidase; Protein kinase G type Iα;
cGMP-dependent protein kinase I promotes cell apoptosis through hyperactivation of death-associated protein kinase 2
Keywords: MLC، زنجیره سبک میوزین; cGK, cGMP-dependent protein kinase; DAPK, death-associated protein kinase; NO, nitric oxide; CaM, calmodulin; MLC, myosin light chain; GST, glutathione S-transferase; PBS, phosphate-buffered saline; GFP, green fluorescent protein; APC, adenomatous polypos
Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves
Keywords: MLC، زنجیره سبک میوزین; BCEC, bovine brain capillary endothelial cells; BK, bradykinin; Cx, connexin; CaMKII, Ca2+/calmodulin-dependent kinase II; DF, dextran fluorescein; ICW, intercellular Ca2+ wave; IP3, inositol-trisphosphate; LY, lucifer yellow; MLC, myosin light chain; PKC
Atorvastatin preserves the integrity of endothelial adherens junctions by inhibiting vascular endothelial cadherin tyrosine phosphorylation
Keywords: MLC، زنجیره سبک میوزین; VE-cad, vascular endothelial cadherin; Tyr, tyrosine; ECs, endothelial cells; AJs, adherens junctions; IL-1β, interleukin-1β; MLC, myosin light chain; TEM, transendothelial migration; Pyk2, proline-rich tyrosine kinase 2; FPP, farnesyl pyrophosphate; GGPP
Intraradial administration of fasudil inhibits augmented Rho kinase activity to effectively dilate the spastic radial artery during coronary artery bypass grafting surgery
Keywords: MLC، زنجیره سبک میوزین; 23.1CABG, coronary artery bypass grafting; 5-HT, 5-hydroxytryptamine; MLC, myosin light chain; MLCP, myosin light chain phosphatase; MYPT1, myosin phosphatase targeting subunit 1; NA, noradrenalin; RA, radial artery; ROCK, Rho kinase; VG, verapamil–glycer
Curcumin has bright prospects for the treatment of multiple sclerosis
Keywords: MLC، زنجیره سبک میوزین; AD, Alzheimer's disease; BBB, blood–brain barrier; CNS, central nervous system; EAE, experimental autoimmune encephalomyelitis; IL-17, interleukin-17; MLC, myosin light chain; MS, multiple sclerosisAutoimmune disease; Curcumin; Multiple sclerosis; Experim
7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration
Keywords: MLC، زنجیره سبک میوزین; ROCK, Rho-associated coiled-coil forming protein kinase; MLC, myosin light chain; MBS, myosin binding subunit; DMSO, dimethyl sulfoxide; PI, propidium iodide; MTT, 3-(4,5-dimethyl-thiazol-2-yl) 2,5-diphenyl tetrazolium bromide; FBS, fetal bovine serum; ER
RhoA and NF-κB are involved in lipopolysaccharide-induced brain microvascular cell line hyperpermeability
Keywords: MLC، زنجیره سبک میوزین; lipopolysaccharide; tight junction; RhoA; NF-κB; permeability; brain microvascular endothelial cellsBBB, blood brain barrier; LPS, lipopolysaccharide; MLC, myosin light chain; TEER, transendothelial electrical resistance; TJs, tight junctions; ZO-1, zonul
LIM-kinase is critical for the mesenchymal-to-amoeboid cell morphological transition in 3D matrices
Keywords: MLC، زنجیره سبک میوزین; LIM-kinase; Cofilin; Rho; Mesenchymal-amoeboid transition; Tumor invasionDMEM, Dulbecco’s modified Eagle’s medium; ECM, extracellular matrix; LIMK, LIM-kinase; MLC, myosin light chain; MMP, matrix metalloprotease; PI, protease inhibitor; SSH, Slingshot; W
Interleukin-4 upregulates RhoA protein via an activation of STAT6 in cultured human bronchial smooth muscle cells
Keywords: MLC، زنجیره سبک میوزین; BSM, bronchial smooth muscle; AHR, airway hyperresponsiveness; MLC, myosin light chain; IL, interleukin; STAT, signal transducer and activator of transcription; hEGF, human epidermal growth factor; hFGF-b, human fibroblast growth factor-basic; GAPDH, glyc
Effect of tongxinluo on vasoconstriction induced by the chronic injury of the adventitia in the rat carotid artery
Keywords: MLC، زنجیره سبک میوزین; ANOVA, one-way analysis of variance; ECL, enhanced chemiluminescence; GAPDH, glyceraldehydes phosphate dehydrogenase; LA, lumen area; MD, media diameter; MLC, myosin light chain; MLCP, myosin light chain phosphatase; MYPT1, myosin-binding subunit of myosi
Role of protein kinase Cζ in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers
Keywords: MLC، زنجیره سبک میوزین; HMEC, human dermal microvessel endothelial cells; IEJs, inter-endothelial junctions; TER, transendothelial electrical resistance; MLC, myosin light chain; dn, dominant-negative; PKC, protein kinase C; PMA, phorbol 12-myristate 13-acetate; 4α-PDD, 4α-phorb
Regulation of myofibroblast activities: Calcium pulls some strings behind the scene
Keywords: MLC، زنجیره سبک میوزین; α-SMA, α-smooth muscle actin; [Ca2+]i, intracellular free cytoplasmic Ca2+ concentration; AJ, adherens junction; AT-II, angiotensin-II; ECM, extracellular matrix; ER, endoplasmic reticulum; ET-1, endothelin-1; FN, fibronectin; MLC, myosin light chain; MLC
Cytokinesis and cancer: Polo loves ROCK‘n’ Rho(A)
Keywords: MLC، زنجیره سبک میوزین; Polo-like kinase 1; RhoA GTPase; Rho kinase; cytokinesisPlk1, Polo-like kinase 1; GEF, guanine nucleotide-exchange factor; GAP, GTPase-activating protein; ROCK, Rho-associated coiled- coil-forming kinase; MLC, myosin light chain
Regulatory mechanisms in lymphatic vessel contraction under normal and inflammatory conditions
Keywords: MLC، زنجیره سبک میوزین; SM, smooth muscle; MHC, myosin heavy chain; MLC, myosin light chain; MLCK, myosin light chain kinase; MLCP, myosin light chain phosphatase; TM, tropomyosin; CaD, caldesmon; ERK, extracellular regulated kinase; Tn, troponin; TXA2, thromboxane A2; PAR2, pro
Effects of raloxifene on cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits
Keywords: MLC، زنجیره سبک میوزین; cGMP, cyclic guanosine monophosphate; ER, estrogen receptor; MLC, myosin light chain; NO, endothelin-derived relaxing factor, nitrous oxide; RLX, raloxifene; SAH, subarachnoid hemorrhage; SERM, selective estrogen receptor modulator; VDCC, voltage-dependen
The mechanism of vasorelaxation induced by Schisandra chinensis extract in rat thoracic aorta
Keywords: MLC، زنجیره سبک میوزین; SC, Schisandra chinensis; SCHE, hexane extract of Schisandra chinensis; MLC, myosin light chain; NO, nitric oxide; l-NAME, NG-nitro-l-arginine methyl ester; ODQ, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one; PE, phenylephrineSchisandra chinensis; Hexane e
Sarcoplasmic calcium-binding protein is an EF-hand–type protein identified as a new shrimp allergen
Keywords: MLC، زنجیره سبک میوزین; Allergen; Crustacea; shellfish; shrimp; recombinant; Lit v 4; sarcoplasmic calcium-binding proteinBS, Boiled shrimp; MLC, Myosin light chain; LC-MS/MS, Liquid chromatography mass spectrometry of maximum sensitivity; MW, Molecular weight; r, Recombinant; R
Contribution of cathepsins B, L and D to muscle protein profiles correlated with texture in rainbow trout (Oncorhynchus mykiss)
Keywords: MLC، زنجیره سبک میوزین; DMSO, dimethyl sulfoxide; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; GP, glycogen phosphorylase; MALDI–ToF, matrix-assisted laser desorption ionisation–time of flight; MHC, myosin heavy chain; MLC, myosin light chain; MS, mass spectrometr
RhoA/ROCK I signalling downstream of the P2Y13 ADP-receptor controls HDL endocytosis in human hepatocytes
Keywords: MLC، زنجیره سبک میوزین; HDL, High density lipoprotein; ROCK, rho-associated kinase; MLC, Myosin light chain; AR-C69931MX, N6-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)-β,γ-dichloromethylene ATP; GPCR, G-protein coupled receptor; PH domain, Pleckstrin homology domain; PtdI
Gα13 regulates methacholine-induced contraction of bronchial smooth muscle via phosphorylation of MLC20
Keywords: MLC، زنجیره سبک میوزین; GPCRs, G-protein-coupled receptors; G-proteins, GTP-binding proteins; MEF, murine embryonic fibroblast; BSMC, bronchial smooth muscle cell; WT, wild type; KO, knockout; KD, knockdown; MLC, myosin light chain; PCR, polymerase chain reaction; SMA, smooth mu
Diabetic Bladder Dysfunction: Current Translational Knowledge
Keywords: MLC، زنجیره سبک میوزین; urinary bladder; diabetes mellitus; urination disorders; complications; epidemiologyDBD, diabetic bladder dysfunction; DM, diabetes mellitus; DSM, detrusor smooth muscle; LUT, lower urinary tract; MLC, myosin light chain; MLCP, MLC phosphatase; PCR, polym
Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases
Keywords: MLC، زنجیره سبک میوزین; F-actin, filamentous actin; BAEC, bovine aortic endothelial cells; GTPases, guanine trinucleotide phosphatases; ILK, integrin-linked kinase; siRNA, small interfering RNA; ROCK, Rho-associated kinase; MLC, myosin light chain; MLCK, myosin light chain kinas
The Role of the N-Terminus of the Myosin Essential Light Chain in Cardiac Muscle Contraction
Keywords: MLC، زنجیره سبک میوزین; ELC, essential light chain; Tg, transgenic; Tg-WT, human ventricular ELC wild type; Tg-Δ43, 43-amino-acid N-terminal truncation mutant; MHC, myosin heavy chain; MLC, myosin light chain; RLC, regulatory light chain; huELCv, human ventricular ELC; FHC, fami
Cofilin mediates tight-junction opening by redistributing actin and tight-junction proteins
Keywords: MLC، زنجیره سبک میوزین; Cofilin; Tight-junction; Caco-2 cells; Capsaicin; Actin alterationCFS, Ca2+-free solution; CyA, cyclosporin A; Cyto B, cytochalasin B; MLC, myosin light chain; MLCK, myosin light chain kinase; OA, okadaic acid; P-cofilin, phosphorylated cofilin; P-MLC, ph
A Rho-kinase inhibitor improves cardiac function after 24-hour heart preservation
Keywords: MLC، زنجیره سبک میوزین; CBF, coronary blood flow; CKMB, creatine kinase–MB; Ct, cycle threshold; eNOS, endothelial nitric oxide synthase; LAP, left atrial pressure; LV, left ventricular; MLC, myosin light chain; NO, nitric oxide; p-MLC, phosphorylated myosin light chain; RKI, Rh
Myosin light chain is a novel shrimp allergen, Lit v 3
Keywords: MLC، زنجیره سبک میوزین; Myosin light chain; allergen; crustacean; shrimp; recombinant; Lit v 32-D, Two-dimensional; MALDI, Matrix-assisted laser desorption/ionization; MLC, Myosin light chain; MS, Mass spectrometry
Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor
Keywords: MLC، زنجیره سبک میوزین; CA, constitutively active; DN, dominant negative; EMT, epithelial–mesenchymal transition; LCM, low-Ca2+ medium; MLC, myosin light chain; MRTF, myocardin-related transcription factor; PAK, p21-activated kinase; PBD, p21 binding domain; ROK, Rho kinase; SFM
Vascular smooth muscle dysfunction induced by monomethylarsonous acid (MMAIII): A contributing factor to arsenic-associated cardiovascular diseases
Keywords: MLC، زنجیره سبک میوزین; Smooth muscle dysfunction; Arsenic; Monomethylarsonous acid (MMAIII); Vasoconstriction; Cardiovascular diseasesET-1, Endothelin-1; KR, Krebs–Ringer; LDH, Lactate dehydrogenase; MLC, Myosin light chain; MMAIII, Monomethylarsonous acid; SMC, Smooth muscle c
Rho GTPases in cancer cell biology
Keywords: MLC، زنجیره سبک میوزین; ECM, extracellular matrix; JNK, Jun N-terminal kinase; MLC, myosin light chain; MMP, matrix metalloproteases; PAK, p21-activated kinase; PKA, cAMP-dependent protein kinase; ROCK, Rho-associated, coiled-coil containing protein kinaseRho GTPases; Cytoskelet
Slow motility in hair cells of the frog amphibian papilla: Myosin light chain-mediated shape change
Keywords: MLC، زنجیره سبک میوزین; AP, amphibian papilla; [Ca2+]i, intracellular free calcium concentration; CaM, calmodulin; CaMK, multifunctional Ca2+/CaM-dependent kinase; DIC, differential interference contrast; DMPP, 1,1-dimethyl-4-henylpiperazinium iodide; MLC, myosin light chain; ML
Involvement of a Rho-ROCK-JNK pathway in arsenic trioxide-induced apoptosis in chronic myelogenous leukemia cells
Keywords: MLC، زنجیره سبک میوزین; APL, acute promyelocytic leukemia; CML, chronic myelogenous leukemia; JNK, c-Jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; DN MKK, dominant negative MAPK kinase; MLC, myosin light chain; GEF, guanine nucleotide exchange factorArsenic tr
Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts
Keywords: MLC، زنجیره سبک میوزین; SPC, sphingosylphosphorylcholine; SrcPTKs, Src family protein tyrosine kinases; ROCK, Rho-kinase; LPA, l-α-lysophosphatidic acid; MYPT1, myosin phosphatase target subunit 1; MLCP, myosin light chain phosphatase; MLC, myosin light chain; FAK, focal adhesio
Protection of cardiomyocyte function by propofol during simulated ischemia is associated with a direct action to reduce pro-oxidant activity
Keywords: MLC، زنجیره سبک میوزین; CCT, creatine–carnitine–taurine; PBS, phosphate-buffered saline; FCS, fetal calf serum; MDA, malondialdehyde; 4-HNE, 4-hydroxy-2-nonenal; BSA, bovine serum albumin; PKC, protein kinase C; MLC, myosin light chain; MPTP, mitochondrial permeability transitio
H-ras Inhibits RhoA/ROCK Leading to a Decrease in the Basal Tone in the Internal Anal Sphincter
Keywords: MLC، زنجیره سبک میوزین; IAS, internal anal sphincter; IOD, integrated optical density; MLC, myosin light chain; MLCP, MLC-phosphatase; MYPT1, the inhibitory subunit of myosin light chain phosphatase; NCM, nitrocellulose membrane; PCR, polymerase chain reaction; ROCK, Rho kinase;
The role of actin, actomyosin and microtubules in defining cell shape during the differentiation of Naegleria amebae into flagellates
Keywords: MLC، زنجیره سبک میوزین; Naegleria; Actin; Actomyosin; Cytoskeleton; Microtubules; TubulinBDM, 2, 3-butanedione monoxime; CD, cytochalasin D; LatA, latrunculin A; MAPs, microtubule-associated proteins; MLC, myosin light chain; MLCK, myosin light chain kinase; MTC, microtubule cyt
What Limits the Velocity of Fast-skeletal Muscle Contraction in Mammals?
Keywords: MLC، زنجیره سبک میوزین; myosin isoforms; temperature dependence; fast kinetics; flash photoplysis; subfragment 1HMM, heavy meromyosin; MHC, myosin heavy chain; MLC, myosin light chain; S1, myosin subfragment 1
Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells
Keywords: MLC، زنجیره سبک میوزین; ROCK, Rho kinase; MLC, myosin light chain; GlcNAc, N-acetyl glucosamine; WGA, wheat germ agglutinin; PMA, phorbol 12-myrisate 13-acetate; PS, phosphatidylserine; caROCK-I, constitutively active ROCK-I; BFA, brefeldin ARho kinase; ROCK; Execution; Apoptosi
Theoretical model of the interactions between Ca2+, calmodulin and myosin light chain kinase
Keywords: MLC، زنجیره سبک میوزین; CaM, calmodulin; MLCK, myosin light chain kinase; MLC, myosin light chain; CaMKII, calmodulin kinase IICalcium; Calmodulin; Myosin light chain kinase; Mathematical model
ALK5 and Smad4 are involved in TGF-β1-induced pulmonary endothelial permeability
Keywords: MLC، زنجیره سبک میوزین; ALK, activin receptor-like kinase; EC, endothelial cell; MLC, myosin light chain; MYPT1, myosin phosphatase regulatory subunit 1; RDU, relative density units; TER, transendothelial electrical resistance; TGFβ1, transforming growth factor beta 1; TβRI, TGF
Inhibition of RhoA-mediated SRF activation by p116Rip
Keywords: MLC، زنجیره سبک میوزین; GFP, green fluorescent protein; GST, glutathione S-transferase; HA, hemagglutinin; LPA, lysophosphatidic acid; MLC, myosin light chain; MBS, myosin-binding subunit of MLC phosphatase; ROCK, Rho-kinase; SRE, serum response element; SRF, serum response fact