Theoretical study on potency and selectivity of novel non-peptide inhibitors of matrix metalloproteinases MMP-1 and MMP-3
Keywords: MMP; Inhibitors; Modeling;
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A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells
Keywords: MEK; mitogen-activated protein/extracellular signal-regulated kinase; TPA; 12-O-tetradecanoyl phorbol 13-acetate; MMP; matrix metalloproteinase; ERK; extracellular regulated kinases; HEPT; 3,5,6,7,8,3â²,4â²-heptamethoxyflavone; MEM; Eagle's minimum es
Assessment of systemic vasculitis
Keywords: ACE; Angiotensin converting enzyme; ACR; American College of Rheumatology; ANA; Anti-nuclear antibody; ANCA; Anti-neutrophil cytoplasm antibody; BVAS; Birmingham Vasculitis Activity Score; CRP; C reactive protein; CSS; Churg-Strauss syndrome; CT; Comput
S-Allylcysteine reduces breast tumor cell adhesion and invasion
Keywords: Breast cancer; E-cadherin; Garlic; Matrix metalloprotease; Metastasis; MDA-MB-231; MMP; SAC; S-Allylcysteine; Tumor growth;
HL-37, a novel anthracene derivative, induces Ca2+-mediated apoptosis in human breast cancer cells
Keywords: Rh123; rhodamine123; PI; propidium iodide; MMP; mitochondrial membrane potential; FCS; fetal calf serum; IC50; concentration resulting in 50% inhibition of cell growth; MTT; 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium bromide; [Ca2+]i; intracellular f
Guggulsterone blocks IL-1β-mediated inflammatory responses by suppressing NF-κB activation in fibroblast-like synoviocytes
Keywords: Guggulsterone; IL-1β; MMP; Fibroblast-like synoviocytes; NF-κB
A Critical Role for Matrix Metalloproteinases in Liver Regeneration 1
Keywords: matrix metalloproteinase; MMP; liver regeneration; IL-6; TNF-α; microvessel density; metalloproteinase inhibitor; Marimastat
Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M
Keywords: Aggrecanase; ADAMTS; MMP; Hyaluronidase; IL-1; TNFα
Role of basement membrane in EMMPRIN/CD147 induction in rat tracheal epithelial cells
Keywords: EMMPRIN; Extracellular matrix; Laminin; Basement membrane; Type IV collagen; MMP;
Asociación de la metaloproteinasa-10 y el tabaquismo en sujetos sin enfermedad cardiovascular
Keywords: Tabaquismo; Metaloproteinasas; Inflamación; Riesgo cardiovascular; Smoking; Metalloproteinases; Inflammation; Cardiovascular risk; EIMc; espesor Ãntima-media carotÃdeo; IL-6; interleucina 6; MEC; matriz extracelular; MMP; metaloproteinasa; MT-MMP; meta
Relaxin stimulates MMP-2 and α-smooth muscle actin expression by human periodontal ligament cells
Keywords: MMP; Relaxin; Periodontal ligament; Fibroblasts; α-SMA
Hepatic expression of A Disintegrin And Metalloproteinase (ADAM) and ADAMs with thrombospondin motives (ADAM-TS) enzymes in patients with chronic liver diseases
Keywords: ADAM; A Disintegrin And Metalloproteinase; MMP; matrix metalloproteinase; ECM; extracellular matrix; TIMP; tissue inhibitor of metalloproteinases; HSC; hepatic stellate cells; A Disintegrin And Metalloprotease (ADAM); Matrix metalloprotease (MMP); Liver f
Matrix metabolism rate differs in functionally distinct tendons
Keywords: Matrix; Turnover; Collagen; MMP; Tendon;
Metalloproteinase Gene Expression Correlates With Clinical Outcome in Dupuytren's Disease
Keywords: ADAMTS; Dupuytren's Disease; gene expression; MMP; TIMP
The Rat Femoral Arteriovenous Fistula Model: Increased Expression of Matrix Metalloproteinase-2 and â9 at the Venous Stenosis
Keywords: AV; arteriovenous; MMP; matrix metalloproteinase; PTFE; polytetrafluoroethylene; TIMP; tissue inhibitor of matrix metalloproteinase;
Expression of Hypoxia Inducible Factor-1α, Macrophage Migration Inhibition Factor, Matrix Metalloproteinase-2 and â9, and Their Inhibitors in Hemodialysis Grafts and Arteriovenous Fistulas
Keywords: AVF; arteriovenous fistula; HIF-1α; hypoxia inducible factor-1α; IgG; immunoglobulin G; MIF; macrophage migration inhibition factor; MMP; matrix metalloproteinase; PTFE; polytetrafluoroethylene; SDS; sodium dodecyl sulfate; TIMP; tissue inhibitor of m
Prevention of methylmercury-induced mitochondrial depolarization, glutathione depletion and cell death by 15-deoxy-delta-12,14-prostaglandin J2
Keywords: 15d-PGJ2; 15-deoxy-delta-12,14-prostaglandin J2; BSO; d,l-buthionine-(S,R)-sulfoximine; HBSS; Hank's balanced salt solution; HO-1; heme oxygenase-1; JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â²-tetraethylbenzimidazolocarbocyanine iodide; MeHg; methylme
Increased glomerular matrix metalloproteinase activity in murine lupus nephritis
Keywords: MMP; lupus nephritis; glomerulonephritis; GBM; collagen IV; lipocalin-2
Matrix Metalloproteinase Inhibition Reduces Contraction by Dupuytren Fibroblasts
Keywords: Dupuytren; ilomastat; MMP; recurrent contracture
Regulation of mRNAs encoding MMP-9 and MMP-2, and their inhibitors TIMP-1 and TIMP-2 by androgens in the rat ventral prostate
Keywords: Actinomycin D; Antiandrogen; Castration; Flutamide; MMP; TIMP
Dense collagen matrix accelerates osteogenic differentiation and rescues the apoptotic response to MMP inhibition
Keywords: Dense collagen; Osteoblast; MMP; Mineralisation; Biomechanics
Oxidative stress and matrix metalloproteinase-9 activity in the liver after hypoxia and reoxygenation with 21% or 100% oxygen in newborn piglets
Keywords: Hypoxia-reoxygenation; Histology; MMP; Glutathione; Energy;
Licochalcone A inhibits the formation and bone resorptive activity of osteoclasts
Keywords: Licochalcone A; Osteoclast formation; Bone resorption; ERK; NF-κB; Fra-2; AP; activator protein; ATP6v0d2; v-ATPase V0 subunit d2; BMM; bone marrow-derived macrophage; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; GAPDH; glyceralde
Follow-up of Endovascular Aneurysm Repair: Plain Radiography, Ultrasound, CT/CT Angiography, MR Imaging/MR Angiography, or What?
Keywords: AAA; abdominal aortic aneurysm; EVAR; endovascular aneurysm repair; MMP; matrix metalloproteinase;
Brain regional and cellular localization of gelatinase activity in rat that have undergone transient middle cerebral artery occlusion
Keywords: GM6001; in situ zymography; reperfusion injury; stroke; matrix metalloproteinases; neuroinflammation; BBB; blood-brain barrier; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DQ; dye quenched; ECM; extracellular matrix; GM6001; N-[(2R)-2-(hydrox
Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation
Keywords: MMP; Invasion; HDAC; Ceramide; Lung;
Identification of a lepidopteran matrix metalloproteinase with dual roles in metamorphosis and innate immunity
Keywords: Matrix metalloproteinase; Innate immunity; Metamorphosis; Galleria mellonella; Insects; Danger model; MMP; matrix metalloproteinases; LPS; lipopolysaccharide; RT-PCR; reverse transcriptase polymerase chain reaction;
Preparation and characterization of chitosan microspheres for doxycycline delivery
Keywords: Chitosan microspheres; Doxycycline; Biocompatibility; Fibroblasts; MMP
Infrared plus visible light and heat from natural sunlight participate in the expression of MMPs and type I procollagen as well as infiltration of inflammatory cell in human skin in vivo
Keywords: Infrared; Heat; MMP; Type I procollagen; Natural sunlight
Sleep Disorders and the Eye
Keywords: CPAP; continuous positive airway pressure; ICP; intracranial pressure; IOP; intraocular pressure; MMP; matrix metalloproteinase; NAION; nonarteritic anterior ischemic optic neuropathy; NTG; normal-tension glaucoma; OSA; obstructive sleep apnea/hypopnea sy
Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells
Keywords: AMI; acute myocardial infarction; BLI; bioluminescence imaging; Ees; end-systolic elastance; EMax; maximal elastance; fluc; firefly luciferase gene; GFP; green fluorescent protein; LAD; left anterior descending coronary artery; LVEF; left ventricular ejec
Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: Regulation of NF-κB activation via ROS signal pathway
Keywords: Platycodon grandiflorum; Saponins; MMP; NF-κB; Reactive oxygen species
Sub-clinical necrotic enteritis in broiler chickens: Novel etiological consideration based on ultra-structural and molecular changes in the intestinal tissue
Keywords: Broiler; Clostridium perfringens; Necrotic enteritis; Morphological changes; Electron microscopy; Extra-cellular matrix; MMP
Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes
Keywords: MMP; TIMP; Expression profiling; MAP kinase; Protein synthesis inhibition; Fibroblast
Scar Treatments: Preclinical and Clinical Studies
Keywords: ACE; angiotensin-converting enzyme; bFGF; basic fibroblast growth factor; COX-2; cyclooxygenase-2; MMP; matrix metalloproteinase; PDL; pulsed dye laser; PGE2; prostaglandin E2; TAC; triamcinolone; TGF; transforming growth factor;
S-nitrosylation of proteins at the leading edge of migrating trophoblasts by inducible nitric oxide synthase promotes trophoblast invasion
Keywords: Nitrosylation; Trophoblast; Migration; Invasion; Nitric oxide; MMP;
Small Cell Lung Cancer
Keywords: CI; confidence interval; ED; extensive-stage disease; EGFR; epidermal growth factor receptor; EP; etoposide plus cisplatin; GRP; gastrin-releasing peptide; IGF1; insulin-like growth factor 1; IGF1R; IGF1 receptor; IP; irinotecan plus cisplatin; IV; intrav
Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: Focus on cell-matrix signaling
Keywords: 26; 29; 35; AI; apoptotic index; BAV; bicuspid aortic valve; Bmf; Bcl-2-modifying factor; DAPI; 4â²,6-diamidino-2â²-phenylindole; ECM; extracellular matrix; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MMP; matrix metalloproteinases; mRNA; messenger
Differential expression of matrix metalloproteinases during stimulated ovarian recrudescence in Siberian hamsters (Phodopus sungorus)
Keywords: Ovary; MMP; Seasonal reproduction; Photoperiod; Hamster; Gonad recrudescence
(−)-Epigallocatechin-3-gallate (EGCG) inhibits HGF-induced invasion and metastasis in hypopharyngeal carcinoma cells
Keywords: HGF; EGCG; MMP; uPA; Hypopharnygeal carcinoma
Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge
Keywords: Matrix metalloproteinases; MMP; Metzincins; ADAM; ADAMTS; PCP; Procollagen C-proteinase; Selective; Inhibitor; Specific; Zn-metalloproteinases; TACE; Hydroxamate; Phosphinic; Zinc-binding group
Tumorigenicity of IL-1α- and IL-1β-Deficient Fibrosarcoma Cells
Keywords: BMC; bone marrow cells; IL-1αâ/â/IL-1βâ/â/IL-1αβâ/â fibrosarcoma; tumors derived from mice with a targeted deletion of the corresponding genes; IL-1comp; IL-1 competent; IL-1Ra; IL-1 receptor antagonist; i.v.; intravenously; MDSC; myeloid-
Targeted Deletion of Metalloproteinase 9 Attenuates Experimental Colitis in Mice: Central Role of Epithelial-Derived MMP
Keywords: DSS; dextran sodium sulfate; ECM; extracellular matrix; fMLP; n-formyl methionine leucine phenylalanine; HBSS; Hanks' balanced salt solution; MMP; matrix metalloproteinase; MPO; myeloperoxidase; PMN; polymorphonuclear neutrophil; t1/2; half time; WT; wi
CD95 Ligand Is a Proliferative and Antiapoptotic Signal in Quiescent Hepatic Stellate Cells
Keywords: BrdU; bromodeoxyuridine; CD95L; CD95 ligand; CHX; cycloheximide; DISC; death-inducing signaling complex; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; HSC; hepatic stellate cell; JNK; c
Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer
Keywords: EGFR; epidermal growth factor receptor; MMP; matrix metalloproteinase; mPIN; mouse prostatic intraepithelial neoplasia; OR; odds ratio; PLAT; tissue plasminogen activator; PLAU; urokinase plasminogen activator; PrEC; primary benign prostate epithelial cel
Epigenetic Changes Induced by Reactive Oxygen Species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter
Keywords: 5-aza-dC; 5-aza-2â²-deoxycytidine; BS; bisulfite sequencing; ChIP; chromatin immunoprecipitation; DNMT; DNA methyltransferase; GPx1; glutathione peroxidase 1; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; MAPK; mitogen-activated protein kinas
The nerve growth factor and its receptors in airway inflammatory diseases
Keywords: ADAM; a disintegrin and metalloprotease domain; AP-1; activating protein 1; AP-2; clathrin adaptative protein-2; APPL; amyloid precursor protein-like; ARMS; ankyrin repeat-rich membrane spanning; BDNF; brain-derived neurotrophic factor; bFGF; basic fibrob
Expression of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) genes in blasts of infant acute lymphoblastic leukemia with organ involvement
Keywords: Leukemia; Dissemination; Organ involvement; Metalloproteinase; MMP; TIMP
Catalytic domain of MMP20 (Enamelysin) – The NMR structure of a new matrix metalloproteinase
Keywords: NMR; Solution structure; Protein–ligand interaction; MMP
Hybrid solar cells based on CuInS2 and organic buffer-sensitizer layers
Keywords: MMP; matrix metalloproteinase; MMP20; matrix metalloproteinase-20 enamelysin; AMEL; amelogenin; PCR; polymerase chain reaction; RT-PCR; reverse transcription PCR; GAPDH; glycerol 3-phosphate dehydrogenase; Poly-A; polyadenylation; mRNA; messenger RNA.; Cu