Cytokine-mediated modulation of MMPs and TIMPs in multipotential neural precursor cells
Keywords: Cytokines; MMP; Multiple sclerosis; TIMP; NPC
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Developmental and hormonal regulation of meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life
Keywords: ADAM19; Testicular development; Hormonal regulation; MMP; Mouse
Transcriptomics and proteomics: Advancing the understanding of genetic basis of fracture healing
Keywords: ALP; alkaline phosphatase; Ang; angiogenin; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; BSP; bone sialoproteins; Cbfα1; core binding factor α1; c-fos; cellular osteosarcoma oncogene; c-myc; cellular myelocytomatosis oncog
Stimulation of human breast carcinoma cell invasiveness and urokinase plasminogen activator activity by glucose deprivation
Keywords: Breast cancer; Glucose; Tumour microenvironment; Invasion; Metastasis; uPA; PAI-1; MMP; Plasmin
Matrix metalloproteinases and their inhibitors as biomarkers for metal toxicity in vitro
Keywords: Chromium; MMP; Cell cycle; Toxicity; Nickel
Mifepristone-induced cervical ripening: Structural, biomechanical, and molecular events
Keywords: Mifepristone; Progesterone; Cervix; Labor; Pregnancy; MMP; Rat
Expression of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) as a prognostic indicator in gastric cancer
Keywords: RECK; Stomach neoplasms; MMP; VEGF; Pathology
Repeated Sputum Inductions Induce a Transient Neutrophilic and Eosinophilic Response
Keywords: eosinophils; inflammation; neutrophils; sputum induction; CO; carbon monoxide; ECP; eosinophilic cationic protein; IL; interleukin; iNOS; inducible nitric oxide synthase; IQR; interquartile range; IVC; inspiratory vital capacity; LTB4; leukotriene B4; MMP
Vascular-wall remodeling of 3 human bypass vessels: Organ culture and smooth muscle cell properties
Keywords: 23; 17; 31; CABG; coronary artery bypass grafting; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; ITA; internal thoracic artery; MMP; Matrix metalloprotease; NIH; neointimal hyperplasia; PBS; phosphate-buffered saline; PDGF; platelet
Molecular modeling of non-covalent binding of homochiral (3S,3′S)-astaxanthin to matrix metalloproteinase-13 (MMP-13)
Keywords: 3S,3′S-Astaxanthin; Astaxanthin; Blind docking; Homochiral astaxanthin; Matrix metalloproteinase; MMP; MMP-13; Molecular modeling
The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells
Keywords: glioma; glioblastoma; mitogen-activated protein kinase kinase; mitogen-activated protein kinase kinase inhibitors; U0126; glial fibrillary acidic protein; BrdU; bromodeoxyuridine; BSA; bovine serum albumin; DAB; 3,3â²-diaminobenzidine; Disc-1; Discovery-
Carboxylated chitooligosaccharides (CCOS) inhibit MMP-9 expression in human fibrosarcoma cells via down-regulation of AP-1
Keywords: AP-1; Activator protein-1; COS; Chitooligosaccharides; CCOS; Carboxylated chitooligosaccharides; ECM; Extracellular matrix; MMP; Matrix metalloproteinase; MTT; 3-(4,5-dimethyl-2-yl)-2,5-diphenyltetrazolium bromide; NF-κB; Nuclerfactor kappa B; PMA; Phorb
TNFα-induced MMP-9 promotes macrophage recruitment into injured peripheral nerve
Keywords: TNF null; Real-time RT-PCR; Taqman, macrophage migration; MMP; Schwann cell
The Ets transcription factors of the PEA3 group: Transcriptional regulators in metastasis
Keywords: Metastasis; Transcription factor; Ets; PEA3 group; MMP
Inhibition of matrix metalloproteinase activity in DU145 human prostate cancer cells by flavonoids from lowbush blueberry (Vaccinium angustifolium): possible roles for protein kinase C and mitogen-activated protein-kinase-mediated events
Keywords: Flavonoids; MMP; PKC; MAP kinase; Blueberry; Cells
Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression
Keywords: MMP; ADAMTS; Fracture healing; Transcriptional profiling
Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease)
Keywords: Skeletal muscle; Wasting; Chronic obstructive pulmonary disease (COPD); Therapeutic strategies; AECOPD; acute exacerbation of COPD; ATP; adenosine triphosphate; Cdk; cyclin-dependent kinases; COPD; chronic obstructive pulmonary disease; FEV1; forced expir
Therapeutic peptides: Targeting the mitochondrion to modulate apoptosis
Keywords: ANT; adenine nucleotide translocator; Cyt c; cytochrome c; ÎΨm; mitochondrial transmembrane potential; HK; hexokinase; MMP; mitochondrial membrane permeabilization; MUP; 4-methylumbelliferyl phosphate; IM; inner membrane; OM; outer membrane; ROS; reacti
From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling
Keywords: Angiogenesis; Ca2+-dependent K+ channels; Cytochrome P450; Eicosanoids; Endothelium; Hyperpolarization; Membrane potential; Signal transduction; bFGF; basic fibroblast growth factor; BKCa channels; large conductance KCa+ channels; COX; cyclooxygenase; cyc
Matrix metalloproteinase activation and blood–brain barrier breakdown following thrombolysis
Keywords: Focal cerebral ischemia; tPA; MMP; BBB breakdown
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces matrix metalloproteinase (MMP) expression and invasion in A2058 melanoma cells
Keywords: TCDD; AhR; MMP; Melanoma; Invasion; AP-1
Green Tea, the “Asian Paradox,” and Cardiovascular Disease
Keywords: EC; endothelial cells; EGCG; (-)-epigallocatechin-3-gallate; MMP; matrix metalloproteinase; ROS; reactive oxygen species; SMC; smooth muscle cells;
ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells
Keywords: ROCK; MMP; Invasion; Migration; Breast cancer
Tissue inhibitor of metalloproteinases 3 regulates extracellular matrix—Cell signaling during bronchiole branching morphogenesis
Keywords: TIMP; MMP; E-cadherin; ECM; FAK; Fibronectin; Bronchiole branching morphogenesis; Lung development; Epithelial–mesenchymal interactions
Molecular Imaging: A Primer for Interventionalists and Imagers
Keywords: CEA; carcinoembryonic antigen; FDG; fluorodeoxyglucose; HSV1-tk; herpes simplex virus type 1 thymidine kinase; MMP; matrix metalloproteinase; NIR; near-infrared; PET; positron emission tomography; SPECT; single photon emission computed tomography; VEGF; v
Design and synthesis of an orally active matrix metalloproteinase inhibitor
Keywords: MMP; Matrix metalloproteinase inhibitor; Hydroxamate inhibitor; l-Glutamic acid
Design and synthesis of novel metalloproteinase inhibitors
Keywords: MMP; Matrix metalloproteinase inhibitor; Hydroxamate inhibitor; 4-Aminobutyric
Oral treatment options for degenerative joint disease—presence and future
Keywords: Osteoarthritis; Pharmacotherapy; Analgesics; SADOA; NSAID; MMP; COX
Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma
Keywords: EGFR; c-erbB-2; VEGF; MMP; Squamous cell carcinoma;
Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates
Keywords: TACE; MMP; Hydroxamate; Rheumatoid arthritis
Transactivation of the EGF receptor and a PI3 kinase-ATF-1 pathway is involved in the upregulation of NOX1, a catalytic subunit of NADPH oxidase
Keywords: PG; prostaglandin; EGF; epidermal growth factor; ERK; extracellular signal-regulated protein kinase; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; MMP; matrix metalloproteinase; PI3; phosphoinositide 3; NOX1; NADPH oxidase; Prostaglandin F
Plasma transforming growth factor β1, metalloproteinase-1 and tissue inhibitor of metalloproteinases-1 in acute viral hepatitis type B
Keywords: TGF-β; MMP; TIMP; Liver; Hepatitis;
Molecular prognostic factors in resectable non-small cell lung cancer
Keywords: EGFR; epidermal growth factor receptor; TGF; transforming growth factor; VEGF; vascular endothelial growth factor; HGF; hepatocyte growth factor; MMP; matrix metalloproteinases; DAPK; death-associated protein kinase; RASSF1A; ras association domain family
Proteoglycans in axonal regeneration
Keywords: GAG; glycosaminoglycan; CS; chondroitin sulfate; HS; heparan sulfate; KS; keratan sulfate; DS; dermatan sulfate; CSPG; chondroitin sulfate proteoglycan; HSPG; heparan sulfate proteoglycan; KSPG; keratan sulfate proteoglycan; DSPG; dermatan sulfate proteog
Anti-angiogenic effect of the seed extract of Benincasa hispida Cogniaux
Keywords: bFGF; basic fibroblast growth factor; HUVECs; human umbilical vein endothelial cells; MMP; matrix metalloproteinase; EBM; endothelial cell basal medium; EGM; endothelial cell medium; NNGH; N-isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic acid; Beni
Identification of potent and selective MMP-13 inhibitors
Keywords: MMP; Anti-inflammatory
Differential expression of the LGI and SLIT families of genes in human cancer cells
Keywords: GBM; glioblastoma multiforme; MMP; matrix metaloproteinasses; ADPEAF; autosomal dominant partial epilepsy with auditory features; Nb; Neuroblastoma; RCC; renal cell carcinoma; LGI1; leucine-rich, glioma inactivated-1; RT-PCR; reverse transcription polymer
New HIV-Drug Inhibits In Vitro Bladder Cancer Migration and Invasion
Keywords: Chemokines; Bladder cancer; Migration; Invasion; CXCR4 antagonist; 4F-benzoyl-TE14011; MMP;
A mechanistic study of colon cancer growth promoted by cigarette smoke extract
Keywords: 5-LOX; Colon cancer; Cigarette smoke; Angiogenesis; MMP; VEGF1;
Pathogenesis and Natural History of Usual Interstitial Pneumonia
Keywords: idiopathic pulmonary fibrosis; natural history; pathogenesis; usual interstitial pneumonia; vascular remodeling; bFGF; basic fibroblast growth factor; CXC; nonconserved amino acid; ECM; extracellular matrix; ELR; glutamic acid-leucine-arginine; IFN; inter
Ascending Thoracic Aneurysms Are Associated With Decreased Systemic Atherosclerosis
Keywords: aneurysm; aorta; atherosclerosis; dissection; LAD; left anterior descending coronary artery; LCA; left circumflex coronary artery; MMP; matrix metalloproteinase; RCA; right coronary artery;
Regulatory roles of sex hormones in cutaneous biology and immunology
Keywords: AR; androgen receptor; CBP; CREB-binding protein; E2; 17β-estradiol; ER; estrogen receptor; MIF; macrophage migration inhibitory factor; MMP; matrix metalloproteinase; TIMP; tissue inhibitor of metalloproteinase; Estrogen; Androgen; Progesterone; Psorias
Abnormal Extracellular Matrix Metabolism in Chronically Ischemic Skin: A Mechanism for Dermal Failure in Leg Ulcers
Keywords: collagen; MMP; TIMP;
Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
Keywords: CYP2E1; cytochrome P4502E1; GSH; glutathione; MMP; mitochondrial membrane potential; PUFA; polyunsaturated fatty acid; CCl4; carbon tetrachloride; E9 cells; HepG2 cells established by retroviral infection methods which express CYP2E1; E47 cells; HepG2 cel
The effect of orally and vaginally administered misoprostol on inflammatory mediators and cervical ripening during early pregnancy
Keywords: Cervical ripening; Matrix metalloproteinases; Misoprostol; MMP; TIMP;
Hypoxia augments gelatinase activity in a variety of adenocarcinomas in vitro
Keywords: hypoxia; cancer; gelatinase; MMP; invasion; proteases; breast; pancreas; colorectal;
Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia
Keywords: cerebral ischemia; cerebral edema; angiotensin II; matrix metalloproteinases; AT1; angiotensin type 1; MCA:O; middle cerebral artery occlusion; MCA:O/R; middle cerebral artery occlusion followed by reperfusion; MMP; matrix metalloproteinase; MT; membrane
Beneficial and detrimental influences of tissue inhibitor of metalloproteinase-1 (TIMP-1) in tumor progression
Keywords: Tissue inhibitor of metalloproteinase-1; Matrix metalloproteinases; Tumor progression; ADAM; a disintegrin with a metalloproteinase domain; MMP; matrix metalloproteinase; TIMP; tissue inhibitor of metalloproteinase;
Dimethyl celecoxib as a novel non-cyclooxygenase 2 therapy in the treatment of non-small cell lung cancer
Keywords: COX-2; cyclooxygenase 2; DMC; 2,5-dimethyl celecoxib; FBS; fetal bovine serum; FITC; fluorescein isothiocyanate; IL; interleukin; MMP; matrix metalloproteinase; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium,