کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9004637 1119652 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma
چکیده انگلیسی
Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and cervical lymph node metastasis. The aim of this article was to review the expression of epidermal growth factor receptor (EGFR), c-erbB-2, vascular endothelial growth factor (VEGF) and matrix metal loproteinases (MMPs) in HNSCC patients and to study their possible correlation to various clinicopathologic parameters. Based on this review, the expression of EGFR, c-erbB-2, VEGF, or MMPs play important roles for tumor growth, invasion and metastasis in HNSCC. c-erbB receptors, MMPs and VEGF might aid the clinician in the selection of an appropriate therapy for individual patients and help to predict the prognosis of patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 59, Supplement 2, October 2005, Pages S366-S369
نویسندگان
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