Hydroxyproline metabolism in a mouse model of Primary Hyperoxaluria Type 3
Keywords: مدل موش; Primary Hyperoxaluria; Oxalate; Hydroxyproline; Mouse model;
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HspX knock-out in Mycobacterium tuberculosis leads to shorter antibiotic treatment and lower relapse rate in a mouse model - A potential novel therapeutic target
Keywords: مدل موش; Mycobacterium tuberculosis; hspX knock-out mutant; Treatment; Mouse model;
Inhalative IL-10 treatment after bilateral femoral fractures affect pulmonary inflammation in mice
Keywords: مدل موش; Inhalative IL-10; Inflammation; Fracture; Mouse model;
In vivo tumor growth of high-grade serous ovarian cancer cell lines
Keywords: مدل موش; High grade serous ovarian cancer; Xenograft; Pax8; Mouse model
Decrease in CA3 inhibitory network activity during Theiler's virus encephalitis
Keywords: مدل موش; Viral encephalitis; IPSCs; CA3; Mouse model; Mesial temporal sclerosis; Epilepsy;
Recombinant transferrin binding protein A (rTbpA) fragments of Pasteurella multocida serogroup B:2 provide variable protection following homologous challenge in mouse model
Keywords: مدل موش; Immunogenicity; Pasteurella multocida; Mouse model; Recombinant transferrin binding protein A (rTbpA); Protective efficacy
Overexpression of CRY1 protects against the development of atherosclerosis via the TLR/NF-κB pathway
Keywords: مدل موش; Cryptochrome 1 (CRY1); Atherosclerosis; TLR/NF-κB; Mouse model
Original researchGene expression profile of necrotizing enterocolitis model in neonatal mice
Keywords: مدل موش; Necrotizing enterocolitis (NEC); Mouse model; Gene expression;
Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes
Keywords: مدل موش; Autism; Caspr2; Interaction proteomics; Mouse model; Brain
A PB1 T296R substitution enhance polymerase activity and confer a virulent phenotype to a 2009 pandemic H1N1 influenza virus in mice
Keywords: مدل موش; Influenza A virus; H1N1; Mouse model; Virulence;
Effect of topical application of quercetin-3-O-(2″-gallate)-α-l-rhamnopyranoside on atopic dermatitis in NC/Nga mice
Keywords: مدل موش; Quercetin; Atopic dermatitis; Cytokine; Mouse model
Behavioural characteristics of the Prader–Willi syndrome related biallelic Snord116 mouse model
Keywords: مدل موش; SNORD116; MBII-85; HBII-85; Prader–Willi syndrome; Mouse model; Behaviour; Anxiety; Cognition; Social preference
Increased sensitivity to kindling in mice lacking TSP1
Keywords: مدل موش; CNS; central nervous system; EGF; epidermal growth factor; IP; intraperitoneal injection; KO; knock out; PTZ; pentylenetetrazole; PNS; peripheral nervous system; qPCR; quantitative polymerase chain reaction; TSP; thrombospondin; TGF-β; transforming growt
Limited miR-17-92 overexpression drives hematologic malignancies
Keywords: مدل موش; miR-17-92; Mouse model; Lymphoma
Combined peri-ischemic administration of Bβ15-42 in treating ischemia reperfusion injury of the mouse kidney
Keywords: مدل موش; Renal ischemia reperfusion injury; Mouse model; Endothelial dysfunction; Vascular leak; Vascular permeability; FX06;
Quantitative detection of drug dose and spatial distribution in the lung revealed by Cryoslicing Imaging
Keywords: مدل موش; Cryoslicing Imaging; Drug delivery; Fluorescence; Mouse model; Tissue attenuation coefficient;
BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analyses
Keywords: مدل موش; Type-2 diabetes; Obesity; Diabetic neuropathy; Mouse model; Leptin; Gene expression analysis; Functional enrichment; Inflammation; Cytokine; Matrix metalloproteinase;
The potential of adjuvants to improve immune responses against TdaP vaccines: A preclinical evaluation of MF59 and monophosphoryl lipid A
Keywords: مدل موش; Adjuvants; Vaccine formulation; Pertussis; Mouse model;
Modeling hepatitis B virus infection, immunopathology and therapy in mice
Keywords: مدل موش; Hepatitis B virus; Immunopathogenesis; Antiviral therapy; Mouse model;
Suppression of Th2 immune responses by the sulfated polysaccharide from Porphyra haitanensis in tropomyosin-sensitized mice
Keywords: مدل موش; Porphyra haitanensis; Sulfated polysaccharide; Food allergy; Tropomyosin; Th2 immune response; Mouse model;
Therapeutic effect of post-exposure treatment with antiserum on severe fever with thrombocytopenia syndrome (SFTS) in a mouse model of SFTS virus infection
Keywords: مدل موش; Severe fever with thrombocytopenia syndrome; Human antiserum; Mouse model; Post-exposure prophylaxis; Ribavirin;
The type 2 cannabinoid receptor regulates susceptibility to osteoarthritis in mice
Keywords: مدل موش; CB2; Cnr2; Cannabinoids; Osteoarthritis; Cartilage; Mouse model;
Evaluation of the potential therapeutic effects of a double-stranded RNA mimic complexed with polycations in an experimental mouse model of endometriosis
Keywords: مدل موش; Endometriosis; angiogenesis; apoptosis; mouse model; pICPEI
Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength
Keywords: مدل موش; EP1; PGE2; Ovariectomy; Age-related bone loss; Mouse model; Bone homeostasis
The impact of weakly bound 89Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection
Keywords: مدل موش; Zr-89; PET/MR; Mouse model; Cancer; Infection; Aspergillus fumigatus
Dsprul: A spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome
Keywords: مدل موش; CHS, Carvajal-Huerta syndrome; rul, ruffled, Dsp/DSP, desmoplakin gene/protein; tm, targeted mutation; HTS, high throughput sequencing; kD, kilodaltonDsp; Hair shaft; Gene networks; Mouse model; Carvajal-Huerta syndrome
Time Course of Contrast Enhancement by Micro-CT with Dedicated Contrast Agents in Normal Mice and Mice with Hepatocellular Carcinoma
Keywords: مدل موش; Micro-CT; contrast agents; contrast enhancement; hepatocellular carcinoma; mouse model;
Structural analysis and immunogenicity of recombinant major envelope protein (rA27L) of buffalopox virus, a zoonotic Indian vaccinia-like virus
Keywords: مدل موش; Buffalopox virus; Immunogenicity; Indirect-ELISA; Mouse model; Oligomers; Recombinant A27L protein; Structural analysis;
Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model
Keywords: مدل موش; Trisomy 21; Down syndrome; Treatment; Mouse model; Cognition
Cardiac mMCP-4+ mast cell expansion and elevation of IL-6, and CCR1/3 and CXCR2 signaling chemokines in an adjuvant-free mouse model of tree nut allergy
Keywords: مدل موش; Hazelnut allergy; Cardiac mast cell; Intestinal mast cell; Mouse model; Cytokines; Chemokines;
Regulation of IgE production and airway reactivity by CD4âCD8â regulatory T cells
Keywords: مدل موش; AHR; airway hyperreactivity; Alum; aluminium hydroxide; BAL; bronchoalveolar lavage; CTLA-4; cytotoxic T lymphocyte-associated antigen 4; dnTC; CD4âCD8â double-negative T cells; GITR; glucocorticoid-induced TNFR-related protein; HD; high dose immuniza
Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice
Keywords: مدل موش; Abeta; Aging; Alzheimer's disease; Amyloid-beta precursor protein; CA1 pyramidal neurons; Calorie restriction; Entorhinal cortex; Hippocampus; Microarray; Mouse model; qPCR;
Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study
Keywords: مدل موش; Bone marrow-derived cells; Stem cells; Intervertebral disc; Disc degeneration; Bone marrow chimera; Spinal deformity; Mouse model;
Research reportA partial lesion model of Parkinson's disease in mice - Characterization of a 6-OHDA-induced medial forebrain bundle lesion
Keywords: مدل موش; Parkinson's disease; Mouse model; Medial forebrain bundle; 6-Hydroxydopamine; Behavioral test; Prediction model;
Types A and B Niemann-Pick disease
Keywords: مدل موش; Niemann-Pick; acid Sphingomyelinase; sphingomyelin; mouse model; enzyme replacement therapy;
The relevance of EMT in breast cancer metastasis: Correlation or causality?
Keywords: مدل موش; Breast cancer; Cell migration; Epithelial to mesenchymal transition; Metastasis; Mouse model;
Development of ADA Against Recombinant Human Interferon Beta in Immune Tolerant Mice Requires Rapid Recruitment of CD4+ T Cells, Induces Formation of Germinal Centers but Lacks Susceptibility for (Most) Adjuvants
Keywords: مدل موش; immunogenicity; therapeutic interferon beta; mouse model; immune mechanism; vaccine adjuvants; proteins; transgenics; immunology; protein aggregates;
∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis
Keywords: مدل موش; DNMT3B; ΔDNMT3B; ΔDNMT3B-del; DNA methylation; Lung cancer; Mouse model; Tumorigenesis
Syngap1 Haploinsufficiency Damages a Postnatal Critical Period of Pyramidal Cell Structural Maturation Linked to Cortical Circuit Assembly
Keywords: مدل موش; Autism spectrum disorder; Development; Epilepsy; Intellectual disability; Mouse model; Synapse; Syngap1;
Visual impairment in an optineurin mouse model of primary open-angle glaucoma
Keywords: مدل موش; POAG; Neurodegeneration; Optineurin; Retinal ganglion cells; Mouse model; Vision;
Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress
Keywords: مدل موش; Age related macular degeneration; Oxidative stress; Mitochondria; Retinal pigment epithelium; 5-hydroxy-tryptamine 1a receptor; Drug therapy; Mouse model; Superoxide dismutase;
Acinar Cell Production of Leukotriene B4 Contributes to Development of Neurogenic Pancreatitis in Mice
Keywords: مدل موش; Gallstone Pancreatitis; Mouse Model; Neurogenic Inflammation; Secretagogue; Vanilloid5-LO, 5-lipoxygenase; FLAP, 5-lipoxygenase-activating protein; Gpbar-1, G protein-coupled bile acid receptor-1; LTB4, leukotriene B4; MK886, 1[(4-chlorophenyl)methyl]-3-[
Gastrointestinal Autoimmunity Associated With Loss of Central Tolerance to Enteric α-Defensins
Keywords: مدل موش; Mouse Model; Intestinal Crypt; DEFA; MicrobiotaAIRE, autoimmune regulator; APECED, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; cTECs, cortical thymic epithelial cells; EECs, enteroendocrine cells; FACS, fluorescence-activated cell sort
GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease
Keywords: مدل موش; 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3â²,5â²-cyclic adenosine monophosphate;
Trigeminal Inflammatory Compression (TIC) injury induces chronic facial pain and susceptibility to anxiety-related behaviors
Keywords: مدل موش; CCI-ION; chronic constriction injury of the infraorbital nerve; TIC; Trigeminal Inflammatory Compression; chronic orofacial pain; stress-induced analgesia; acoustic startle; mouse model; operant tests; nerve injury;
Disruption of tubular Flcn expression as a mouse model for renal tumor induction
Keywords: مدل موش; BHD; FLCN; gene targeting; kidney cancer; mouse model; mTOR; RCC; TGF-β;
The effect of mild traumatic brain injury on peripheral nervous system pathology in wild-type mice and the G93A mutant mouse model of motor neuron disease
Keywords: مدل موش; ALS; amyotrophic lateral sclerosis; CST; cortical spinal tract; EMG; electromyography; GFAP; glial fibrillary acidic protein; MND; motor neuron disease; RT; room temperature; TBI; traumatic brain injury; TBI; amyotrophic lateral sclerosis; mouse model; ox
Xeno-immunosuppressive properties of human decidual stromal cells in mouse models of alloreactivity in vitro and in vivo
Keywords: مدل موش; cell therapy; decidual stromal cells; graft-versus-host disease; mesenchymal stromal cells; mouse model
Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts
Keywords: مدل موش; GPCR; G protein-coupled receptor; OBs; osteoblasts; TRAP; tartrate-resistant acid phosphatase; FTIR; Fourier transform infrared; SRµCT; synchrotron radiation micro-computed tomography; GFP; green fluorescent protein; qPCR; quantitative real-time polymera
Ablation of Foxl1-Cre-Labeled Hepatic Progenitor Cells and Their Descendants Impairs Recovery of Mice From Liver Injury
Keywords: مدل موش; HPCs; Oval Cells; Mouse Model; Nonalcoholic Fatty Liver Disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CDE; choline-deficient, ethionine-supplemented; CK19; Cytokeratin 19; CreER; Cre-estrogen receptor