دانلود مقالات ISI درباره Mptp + ترجمه فارسی

l-DOPA: A scapegoat for accelerated neurodegeneration in Parkinson's disease?

Keywords: AADC; aromatic l-amino acid decarboxylase; ALDH; aldehyde dehydrogenase; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; AR; aldehyde reeductase; ATP; adenosine triphosphate; Bax; Bcl-2-associated X protein; BDNF; brain-derived neurotrophic fac

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases

Keywords: ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening

Keywords: MPTP; Pioglitazone; Rosiglitazone; Ciglitazone; Troglitazone; Amplex Red; KNIME; MOE-Dock; ERK kinase; PPAR-γ

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition of inducible nitric oxide synthase expression and cell death by (−)-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease

Keywords: Catechins; (−)-Epigallocatechin-3-gallate; Green tea; Inducible nitric oxide synthase; MPTP; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Complex I: Inhibitors, inhibition and neurodegeneration

Keywords: Complex 1; Mitochondria; Tau; Parkinson's disease; Mitochondrial DNA; Annonacin; MPTP;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Decreased RGS9 protein level in the striatum of rodents undergoing MPTP or 6-OHDA neurotoxicity

Keywords: RGS; Striatum; MPTP; 6-OHDA; Western blot

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Protocatechuic acid inhibits neurotoxicity induced by MPTP in vivo

Keywords: Parkinson's disease; Protocatechuic acid; MPTP; Neuroprotection; In vivo

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Gene–environment interactions in Parkinson's disease and other forms of parkinsonism

Keywords: Parkinson; Neurotoxicant; MPTP; Synuclein; Cyanobacteria; Genome

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Keywords: AMPK; MPP+; MPTP; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

5-HT2A receptor antagonists improve motor impairments in the MPTP mouse model of Parkinson’s disease

Keywords: M100907; Motor deficits; MPTP; Ritanserin; SB 206553; Serotonin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

l-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation

Keywords: Monoamine oxidase inhibition; Reactive oxygen species; Dopamine oxidation products; Intact nigrostriatal system; Median forebrain bundle; MPTP; Selegiline; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Age-dependent posttranslational modifications of voltage-dependent anion channel 1

Keywords: AD; Alzheimer's disease; BBE; bovine brain extract; EGM; endothelial growth medium; ESC; embryonic stem cells; FBS; fetal bovine serum; hEGF; human endothelial growth factor; HRP; horse radish peroxidise; Hsp; heat shock protein; HUVEC; human umbilical

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

A rotarod test for evaluation of motor skill learning

Keywords: Rotarod; Motor skill learning; Dopamine; Phasic neurotransmission; MPTP; Parkinson's disease; Mice

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Phenylephrine Induces Early and Late Cardioprotection Through Mitochondrial Permeability Transition Pore in the Isolated Rat Heart

Keywords: ischemia; reperfusion; preconditioning; alpha-1 adrenergic agonist; mPTP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents

Keywords: Parkinson's disease; Mitochondria; Gene expression; Rotenone; MPTP; Dopamine; Substantia nigra; Ventral tegmental area

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: Clinical relevance

Keywords: DA, dopamine; DOPAC, dihydroxyphenylacetic acid; GSH, glutathione; MAO-B, monoamine oxidase-B; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+, 1- methyl-4-phenylpyridinium; TH, tyrosine hydroxylaseZonisamide; Epilepsy; MPTP; MAO-B; Mice; Parkins

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

NeuropharmacologyResearch PaperNeuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease

Keywords: dopamine; adenosine A2A receptor; theophylline; paraxanthine; striatum; neurotoxicity; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; LSD; Least Significance Difference; PD; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Objective and quantitative evaluation of motor function in a monkey model of Parkinson's disease

Keywords: Parkinson's disease; MPTP; Primate model; Video-based analysis; Dopamine transporter;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

The critical role of intracellular zinc in adenosine A2 receptor activation induced cardioprotection against reperfusion injury

Keywords: A2 receptor; Intracellular zinc; NECA; Reperfusion injury; mPTP; Mitochondrial metabolism;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice

Keywords: Parkinson's disease; MPTP; Caspase-3; Apoptosis; Substantia nigra; Striatum;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or l-DOPA in MPTP-treated common marmosets

Keywords: Rotigotine; l-DOPA; Continuous delivery; Dyskinesia; MPTP; Primates; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Preladenant, a selective A2A receptor antagonist, is active in primate models of movement disorders

Keywords: Preladenant; MPTP; Extrapyramidal Syndrome; Monkey; Parkinson's Disease; A2A; Adenosine; Movement disorder

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Oxidants induce alternative splicing of α-synuclein: Implications for Parkinson's disease

Keywords: Synuclein; Parkinson's disease; Oxidative stress; Alternative splicing; Dopamine neurons; MPTP; Neurotoxicity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivo

Keywords: Sevoflurane; Diabetes; Ischaemia; Postconditioning; mPTP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine

Keywords: Rotation; Turning behaviour; Parkinson's disease; Substantia nigra pars compacta; Striatum; MPTP; Apomorphine; Amphetamine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: Implications for Parkinson's disease

Keywords: PD; Parkinson's disease; SN; substantia nigra; GSH; glutathione (reduced); GSSG; glutathione (oxidized); DTNB; 5,5-dithio-bis-2-nitro benzoic acid; ROS; reactive oxygen species; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; γ-GCL; gamma-glutamyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1

Keywords: BKCa; big conductance Ca2+-activated K+-channel (KCa1.1); Clotrimazole; 1-[(2-chlorophenyl)-diphenyl-methyl]imidazole; CsA; Cyclosporin A; DC-EBIO; 5,6-dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one; DMEM; Dulbecco's modified Eagle medium; ER; endopla

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

MPTP-induced dopaminergic degeneration and deficits in object recognition in rats are accompanied by neuroinflammation in the hippocampus

Keywords: Parkinson's disease; Dementia; Object recognition; Neuroinflammation; Microglial activation; MPTP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease

Keywords: Parkinson's disease; MPTP; Motor deficit; Dopamine; Vertical grid test; Horizontal grid test

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The timing of administration, dose dependence and efficacy of dopa decarboxylase inhibitors on the reversal of motor disability produced by L-DOPA in the MPTP-treated common marmoset

Keywords: L-DOPA; Carbidopa; Benserazide; Motor disability; Dyskinesia; MPTP; Primate; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The partial dopamine agonist pardoprunox (SLV308) administered in combination with l-dopa improves efficacy and decreases dyskinesia in MPTP treated common marmosets

Keywords: Pardoprunox (SLV308); Partial agonist; l-dopa; Dyskinesia; MPTP; Common marmoset

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

NeuropharmacologyResearch PaperChanges of AMPA receptors in MPTP monkeys with levodopa-induced dyskinesias

Keywords: glutamate; motor complications; Parkinson; cabergoline; CI-1041; dopamine; DA; dopamine; DL; dorso-lateral; DM; dorso-medial; l-DOPA; levodopa; LTD; long-term depression; LTP; long-term potentiation; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex

Keywords: MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson's disease; PFC, prefrontal cortex; NER, normalized expression rate; FDR, false discovery rateMicroarray; Quantitative PCR; Monkey; Human; Parkinson's disease; MPTP; Brain; Prefrontal cortex

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia

Keywords: PD; Parkinson's disease; 5-HT; 5-hydroxytryptamine; TPH; tryptophan hydroxylase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride; 6-OHDA; 6-hydroxydopamine; Serotonin; Tryptophan hydroxylase; Primate; L-DOPA; Dyskinesia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

Keywords: CsA; cyclosporine A; 5-HD; 5-hydroxydecanoic acid; IPC; ischemic pre-conditioning; I/R; ischemia/reperfusion; LAD; left anterior descending coronary artery; KATP; ATP-sensitive potassium channel; MPTP; mitochondrial permeability transition pore; Myocardia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Research reportExercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse

Keywords: MPTP; Anxiety; Depression; Affective behavior; Mood; Motor; C57BL/6; Male; Mouse;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Dopamine inhibits GABA transmission from the globus pallidus to the thalamic reticular nucleus via presynaptic D4 receptors

Keywords: basal ganglia; dopamine receptors; D4-agonists; Parkinson's disease; sleep disorders; thalamus; ABC; avidin-biotin-peroxidase complex; ACSF; artificial cerebrospinal fluid; CPu; caudate-putamen; DAB; 3,3′-diaminobenzidine tetrahydrochloride; EDS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Transient elevation of adult hippocampal neurogenesis after dopamine depletion

Keywords: Parkinson's disease; Adult neurogenesis; Dentate gyrus; Stem cells; MPTP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides

Keywords: Parkinson's disease; MPTP; Dyskinesia; Levodopa; Neuropeptides; Non-dopaminergic treatments

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

A direct projection from the subthalamic nucleus to the ventral thalamus in monkeys

Keywords: Basal ganglia; MPTP; Hyperdirect pathway; Retrograde tracing; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Exercise protects against MPTP-induced neurotoxicity in mice

Keywords: MPTP; Parkinson's disease; Exercise; Substantia nigra; Proteomics

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

MPTP-induced parkinsonism extends to a subclass of TH-positive neurons in the gut

Keywords: Parkinson's disease; Gut; MPTP; Mouse; DopaminePD, Parkinson's disease; DA, dopamine; LC, locus coeruleus; NE, norepinephrine; GI, gastrointestinal; ENS, enteric nervous system; 6-OHDA, 6-hydroxydopamine; MP, myenteric plexus; TH, tyrosine hydroxylase; SD

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D2/D3 receptor blockade

Keywords: Dopamine; MPTP; l-dopa; Pramipexole; Nociceptin/orphanin FQ; Trap-101; J-113397

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

An in vivo pharmacological evaluation of pardoprunox (SLV308) — A novel combined dopamine D2/D3 receptor partial agonist and 5-HT1A receptor agonist with efficacy in experimental models of Parkinson's disease

Keywords: Pardoprunox (SLV308); Dopamine D2/D3 partial agonist; 5-HT1A agonist; MPTP; Parkinson's

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism

Keywords: Parkinson's disease; Microarray; MPTP; Caffeine; Nicotine; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease

Keywords: Parkinson's disease; MPTP; Echinacoside; GDNF; BDNF; Neurorescue;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Prosurvival effect of human wild-type α-synuclein on MPTP-induced toxicity to central but not peripheral catecholaminergic neurons isolated from transgenic mice

Keywords: α-synuclein transgenic mice; Parkinson's disease; protection against MPTP; nigrostriatal system; peripheral nervous system; α-SYN; alpha-synuclein; DA; dopamine; DAB; 3,3′-diaminobenzidine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenyl acetic

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2010 سفارش ترجمه

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Keywords: Ropinirole; Pramipexole; Pergolide; Antiparkinson; α2-Adrenoceptor; D2 receptor; D3 receptor; ACh; acetylcholine; Akt; atypical kinase; AR; adrenoceptor; BDNF; brain derived neurotrophic factor; COMT; catechol-Ortho-methyltransferase; DA; dopamine; ERK;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2010 سفارش ترجمه

Is there a pathogenic role for mitochondria in Parkinson's disease?

Keywords: DJ1; Mitochondria; MPTP; Neurodegneration; PD; PINK1; Parkin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه