دانلود مقالات ISI درباره Mptp + ترجمه فارسی

Fluorescence assay for mitochondrial permeability transition in cardiomyocytes cultured in a microtiter plate

Keywords: MPTP; Rhodamine-123; Fluorescence; Microtiter plate; Neonatal rat cardiomyocytes; Cell culture

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity

Keywords: ATP content; MPTP; Near-infrared light; Neurotoxicity; Parkinson's disease; Rotenone

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys

Keywords: Dyskinesia; Kynurenic acid; Kynurenine; l-Dopa; MPTP; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore

Keywords: ANT; adenine nucleotide translocase; BKA; bongkrekic acid; CAT; carboxyatractyloside; CsA; cyclosporin A; CyP; cyclophilin; IMM; inner mitochondrial membrane; MPTP; mitochondrial permeability transition pore; NEM; N-ethylmaleimide; PAO; phenylarsine oxide

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons

Keywords: Associated adenoviral vector (AAV); Dopamine; Fetal tissue; Glial derived neurotrophic factor (GDNF); Graft; Monkey; MPTP; Parkinson's disease; Striatum; Transplantation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease

Keywords: Antioxidant; MPTP; 6-OHDA; Parkinson disease; SUN N8075

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Amiloride is neuroprotective in an MPTP model of Parkinson's disease

Keywords: MPTP; Amiloride; Psalmotoxin; Substantia nigra; Parkinson's disease; Dopamine transporter; Tyrosine hydroxylase; ASIC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets

Keywords: Parkinson's disease; MPTP; Common marmosets; Ropinirole; Continuous delivery; Dyskinesia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats

Keywords: Active avoidance; Cognitive impairment; Melatonin; MPTP; Parkinson's disease; Tyrosine hydroxylase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish

Keywords: Monoaminergic; Transgenic; Zebrafish; MPTP; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission

Keywords: Substantia nigra pars compacta; Turning behaviour; Dopamine; Basal ganglia; Dopamine receptor; Parkinson's disease; MPTP; 6-Hydroxydopamine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury

Keywords: Affective behavior; MPTP; Parkinson's disease; Anxiety; Depression; Conditioned fear

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism

Keywords: J-113397; L-DOPA; MPTP; Nociceptin/orphanin FQ; NOP−/− mice; NOP receptor; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular imaging reveals a correlation between 2′-CH3-MPTP-induced neonatal neurotoxicity and dopaminergic neurodegeneration in adult transgenic mice

Keywords: Molecular imaging; Gliosis; GFAP; MPTP; Parkinson's disease; Mouse model;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Caspase-independent apoptosis in yeast

Keywords: Apoptosis; AIF1; EndoG; AMID; MPTP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Pallidal burst activity during therapeutic deep brain stimulation

Keywords: Subthalamic nucleus; Macaque; Basal ganglia; Parkinson's disease; MPTP; Network

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Preclinical development of gene therapy for Parkinson's disease

Keywords: 6-OHDA; 6-hydroxydopamine; AADC; aromatic l-amino acid decarboxylase; AAV; adeno-associated virus; AdV; adenovirus; BH4; tetrahydrobiopterin; CNS; central nervous system; D2; dopamine D2 receptor; GABA; γ-aminobutyric acid; GAD; glutamic acid decarboxyla

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

A novel adenosine A1 and A2A receptor antagonist ASP5854 ameliorates motor impairment in MPTP-treated marmosets: Comparison with existing anti-Parkinson's disease drugs

Keywords: ASP5854, 5-[5-amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1H)-one; l-DOPA, l-3,4-diydroxyphenylalanine; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineAdenosine receptor antagonist; ASP5854; Parkinson's disease; MPTP; Monkeys; Motor dis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Contribution of calpain activation to early stages of hippocampal damage during oxygen-glucose deprivation

Keywords: CsA; cyclosporin A; HSD; hypoxic spreading depression; MPTP; mitochondria permeability transition pore; OGD; oxygen-glucose deprivation; Rh 123; Rhodamine 123; ROI; region of interest; ROS; reactive oxygen species; ΔΨm; mitochondrial membrane potentia

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Exploring the neuroprotective effects of modafinil in a marmoset Parkinson model with immunohistochemistry, magnetic resonance imaging and spectroscopy

Keywords: Modafinil; Marmoset monkey; MPTP; MRI; MRS; Tyrosine hydroxylase; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of magnesium on calcium-induced depolarisation of mitochondrial transmembrane potential

Keywords: Mitochondria; Calcium; Magnesium; Trans-membrane potential; CsA; Cyclosporin A;; mCICR; Ca2+-induced release of Ca2+ from mitochondria; mPTP; mitochondrial permeability transition pore; ΔΨm; mitochondrial trans-membrane potential; RuR; ruthenium red;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Cyclosporine A prevents apoptosis-related mitochondrial dysfunction after neonatal cardioplegic arrest

Keywords: 20; 21; 31; CCP; cold crystalloid cardioplegia; COX IV; cytochrome c oxidase IV; CPB; cardiopulmonary bypass; CsA; cyclosporine A; Ig; immunoglobulin; IV; intravenous; MPTP; mitochondrial permeability transition pore; OCT; optimal cutting temperature; TUN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Repeated intranigral MPTP administration: A new protocol of prolonged locomotor impairment mimicking Parkinson's disease

Keywords: Parkinson's disease; MPTP; Intranigral; Animal model; Tyrosine hydroxylase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Pathophysiology of the basal ganglia and movement disorders: From animal models to human clinical applications

Keywords: Parkinson's disease; MPTP; Primate; Neural network; DBS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Vitamin B12b enhances the cytotoxicity of dithiothreitol

Keywords: AO; acridine orange; B12b; hydroxycobalamine; DCF; 2',7'-dichlorofluorescin; DFO; desferrioxamine; DMEM; Dulbecco's modified Eagle's medium; DTT; dithiothreitol; DTTox; oxidized dithiothreitol; Н2DCFDA; 2',7'-dichlorofluorescin diacetate (2',7'-dichlorod

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

Keywords: EE; Enriched environments; SE; Standard Environment; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; BDNF; Brain-derived neurotrophic factor; cDNA; complementary DNA; MAPK; mitogen-activated protein kinase; GAPDH; Glyceraldehyde-3-phosphate dehydrogen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibition of 6-hydroxydopamine-induced oxidative damage by 4,5-dihydro-3H-2-benzazepine N-oxides

Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; 6-OHDA; 6-hydroxydopamine; MPTP; N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PBN; α-phenyl-N-tert-butylnitrone; ROS; reactive oxygen species; OH; hydroxyl radical; LP

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

In vivo gene delivery for development of mammalian models for Parkinson's disease

Keywords: 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated virus; Ad; adenovirus; CsCl; cesium chloride; DA; dopamine; DAT; dopamine transporter; LRRK2; leucine-rich repeat kinase-2; LV; lentivirus; MFB; medial forebrain bundle; MPTP; N-methyl-4-phenyl-1,2,3,6-tetr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease

Keywords: Cystamine; MPTP; 6-OHDA; Basal ganglia; ATP; Capsase-3; Dopamine

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

A cell-permeable peptide inhibitor TAT-JBD reduces the MPP+-induced caspase-9 activation but does not prevent the dopaminergic degeneration in substantia nigra of rats

Keywords: Akt/PKB; protein kinase B; Apaf-1; apoptotic protease activating factor-1; JNK; c-Jun N-terminal kinase; LEHD; Leu-Glu-His-Asp acid; MAPK; mitogen-activated protein kinase; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrop

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Receptor mosaics of neural and immune communication: Possible implications for basal ganglia functions

Keywords: Ab; amyloid-beta protein; ABGA; antibasal ganglia antibody; AD; Alzheimer's disease; AGE; advanced glycation endproducts; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; CA; cornu ammonis; CB; cannabinoid; CD; cluster designa

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

2,3-Benzodiazepine-type AMPA receptor antagonists and their neuroprotective effects

Keywords: ABP; AMPA receptor-binding protein; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMK-II and IV; Ca2+-calmodulin kinase II and IV; EAE; experimental autoimmune encephalomyelitis; EGIS-8332; (±)-1-(4-aminophenyl)-3-acetyl-4-cyano-4-meth

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

Emerging restorative treatments for Parkinson's disease

Keywords: Ad; adenovirus; AAV; adeno-associated virus; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CD45; cluster of differentiation 45; CNTF; ciliary neurotrophic factor; CSF; cerebrospinal fluid; DAT;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2008 سفارش ترجمه

A chronic mouse model of Parkinson's disease has a reduced gait pattern certainty

Keywords: Variability; Gait; Locomotion; Parkinson's disease; Entropy; MPTP; Probenecid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Use-dependent behavioral and neurochemical asymmetry in MPTP mice

Keywords: MPTP; Behavior; Inactivity; Dopamine; Exercise

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Evaluation of neuroprotective and anti-fatigue effects of sildenafil

Keywords: MPTP; 6-OHDA; Sildenafil; Parkinson's disease; Dopamine; Fatigue

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Mitochondrial dysfunction in Parkinson’s disease

Keywords: Parkinson’s disease; Oxidative stress; Mitochondrial dysfunction; MPTP; MTH1; OGG1; MUTYH

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

N-Methyltetrahydro-β-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic β-carbolinium cations by heme peroxidases

Keywords: MPTP; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-Methyl-4-phenylpyridinium; β-Carbolinium; N-Methyltetrahydro-β-carbolines; Myeloperoxidase; Lactoperoxidase; Horseradish peroxidase; Cytochrome P450; CYP2D6; Monoamine oxidase (MAO); Parkinson’s

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Calorie restriction in nonhuman primates: assessing effects on brain and behavioral aging

Keywords: locomotor activity; MRI; PET; basal ganglia; neuroprotection; DNA; AL; ad libitum fed; BDNF; brain derived neurotrophic factor; CR; calorie restriction; DA; dopamine; D2R; D2 dopamine receptor; MAP; motor assessment panel; MCI; mild cognitive impairment;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

The role of poly(ADP-ribose) polymerase-1 in CNS disease

Keywords: DNA; transcription; inflammation; cell death; oxidative stress; AIF; apoptosis-inducing factor; DPQ 3; 4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone; EAE; experimental allergic encephalomyelitis; GPI 6150; 1,11b-dihydro-[2H]benzopyrano[4,3,2-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson’s disease

Keywords: Parkinson’s disease; Diffusion tensor imaging; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPTP; Substantia nigra; Striatum; Dopaminergic neurons

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: Pharmacological validation with R-(−)-deprenyl

Keywords: Mice; MPTP; Beam-walking apparatus; R-(−)-Deprenyl; Dopamine; Tyrosine hydroxylase; Striatum; Substantia nigra;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Gene–environment interactions in Parkinson's disease

Keywords: Parkinson's disease model; Environmental factor; LRRK2; alpha-Synuclein; MPTP; Rotenone

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult

Keywords: MPTP; rotenone; hypothalamus; susceptibility; neurodegeneration; tyrosine hydroxylaseARC, arcuate nucleus; DA, dopamine; DAT, dopamine transporter; DMSO, dimethylsulfoxide; DOPAC, 3,4-dihyroxyphenylacetic acid; MAO, monoamine oxidase; MBH, mediobasal hypo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of glycogen synthase kinase-3β protects dopaminergic neurons from MPTP toxicity

Keywords: GSK-3β; Indirubin-3′-oxime; AR-A014418; Dopaminergic neurons; MPTP; Parkinson's diseaseAR-A014418, N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl) urea; CGNs, cerebellar granule neurons; FITC, fluorescein isothiocyanate; GSK-3β, glycogen synthase kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

The administration of entacapone prevents l-dopa-induced dyskinesia when added to dopamine agonist therapy in MPTP-treated primates

Keywords: MPTP; Primates; l-dopa; Ropinirole; Entacapone; Dyskinesia; Continuous dopaminergic stimulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Research ReportLipid-lowering drugs in the MPTP mouse model of Parkinson's disease: Fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not

Keywords: HMG-CoA; 3-hydroxy 3-methyl glutaryl co-enzyme A; MAO; monoamine oxidase; MPP+; 1-methyl-4-phenyl pyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; PPAR; peroxisome proliferator-activated receptor; ROS; reactive oxyg

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Quantitative [123I]FP-CIT pinhole SPECT imaging predicts striatal dopamine levels, but not number of nigral neurons in different mouse models of Parkinson's disease

Keywords: Dopamine transporter; FP-CIT; Pinhole SPECT; MPTP; 6-OHDA; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease

Keywords: Echinacoside; Parkinson's disease; MPTP; MPP+; Apoptosis; Caspase-3; Caspase-8

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: increased susceptibility of olfactory bulb

Keywords: Parkinson's disease; MPTP; Oxidative stress; Glutathione; Lipid peroxidation; γ-Glutamyl transpeptidase; Rat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه