Keywords: Predictive biomarkers; Pathology response; Esophageal cancer; Chemo(radio)therapy; Meta-analysis; ESCC; Esophageal squamous cell carcinoma; AC; Adenocarcinoma; TS; Thymidylate synthase; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CYFRA21-1;
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A new method measuring the interaction of radiotracers with the human P-glycoprotein (P-gp) transporter
Keywords: AUC; area under the curve; BCRP; breast cancer resistance protein; Ki; equilibrium inhibitory constant; hMDR1; human multiple drug resistance 1; MDCKII; Madin-Darby Canine Kidney cell line; MRP-1; multiple drug resistance protein 1; PET; positron emission
Research paperTransfer of multidrug resistance among acute myeloid leukemia cells via extracellular vesicles and their microRNA cargo
Keywords: EVs; extracellular vesicles; MRP-1; multidrug resistance protein 1; Pgp; P-glycoprotein 1; EVs/AR; extracellular vesicles generated by HL60/AR cells; EVs/S; extracellular vesicles generated by HL60 cells; HL60/EVs1; HL60 cells receiving one treatment with
Role of MRP-1 and GST-Pi in MDR and their inhibition by indomethacin in AML
Keywords: MDR; multidrug resistance; MRP-1; multidrug resistance-associated protein-1; GST-Pi; Glutathione-S-Transferase-Pi; NSAIDs; non-steroidal anti-inflammatory drugs; AML; acute myeloid leukemia; CR; complete remission; UR; un-remitted; DFS; disease-free survi
Exosomes: Therapy delivery tools and biomarkers of diseases
Keywords: AAV; adeno-associated virus; APC; antigen-presenting cell; CNS; central nervous system; CSF; cerebrospinal fluid; DC; dendritic cell; EBV; Epstein-Barr virus; EGFR; epidermal growth factor receptor; EEF; eukaryotic elongation factors; ESCRT; endosomal-sor
Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells
Keywords: ApppI; triphosphoric acid 1-adenosin-5â²-yl ester 3-(3-methylbut-3-enyl) ester; ECL; enhanced chemiluminescence; FPPS; farnesyl pyrophosphate synthase; FOH; farnesol; GGOH; geranylgraniol; HMGR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; HPLC-ESI
Sp1 transcription factor: A long-standing target in cancer chemotherapy
Keywords: Anticancer drugs; Prognosis; Sp1; Sp3; Transcription factors; Targeted therapy; AMPKα; AMP-activated protein kinase alpha catalytic subunit; Bcl-2; B cell/lymphoma 2; Bcl-w; member of the Bcl-2 family; Bid; BH3 interacting domain death agonist; CDK; cycl
Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: Implication of reconstituted tumor microenvironment and multidrug resistance phenotype
Keywords: DCFDA; dichlorodihydrofluorescein diacetate; DL; Dalton's lymphoma; FASN; fatty acid synthase; iNOS; inducible nitric oxide synthase; MRP-1; multidrug resistant associated protein-1; MDR; multidrug resistant protein; NO; nitric oxide; ROS; reactive oxygen
Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein
Keywords: Triterpenes; Doxorubicin; MRP-1; Drug resistance; Soft tissue sarcomas
Nanomedicines in the future of pediatric therapy
Keywords: ACTs; artemisinin combined therapies; ALN; alendronate; ANMAT; Administración Nacional de Medicamentos, Alimentos y TecnologÃa Médica; ARV; antiretrovirals; AS; antisense; AUC; area-under-the-curve; BMS; burning mouth syndrome; CD; cytosine deaminase;
Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies
Keywords: Stathmin; P-glycoprotein; Resistance; Taxane; p53; HER2; BRCA1/2; MRP-1;
Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain
Keywords: adriamycin (doxorubicin); glutathione; glutathione-related enzymes; oxidative stress; chemobrain; proteomics; ADR; adriamycin; BBB; blood brain barrier; GFAP; glial fibrillary acidic protein; GPx; glutathione peroxidise; GR; glutathione reductase; GSH;
Convergence of nitric oxide and lipid signaling: Anti-inflammatory nitro-fatty acids
Keywords: âNO; nitric oxide; sGC; soluble guanylate cyclase; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; LOX; lipoxygenase; NO2-FA; nitrated fatty acids; NOS; nitric oxide synthase; ONOO-; peroxynitrite; RSNO; nitrosothiols; PUFAs; polyunsaturated
Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5-a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines
Keywords: Condensed 1,2,4-triazine; Benzimidazole; Hydrazones; Topoisomerase; MRP-1; Pgp
MRP-1 expression levels determine strain-specific susceptibility to sodium arsenic-induced renal injury between C57BL/6 and BALB/c mice
Keywords: Arsenic; acute renal injury; strain susceptibility; MRP-1;
Monoclonal antibody 5C3 raised against formalin fixed paraffin-embedded invasive breast tumour tissue: Characterisation of its reactive antigen via immunoprecipitation and internal sequencing
Keywords: ABC; avidin-biotin complex; ATCC; American Type Tissue Culture Collection; BCA protein assay; bicinchonic acid protein assay; CMF; cyclophosphamide methotrexate 5-fluorouracil; DAB; 3-3,diaminobenzidine tetrachloride; DCIS; ductal carcinoma in situ; ECACC