Keywords: میوتوکسین; Immunotoxicology; Inflammation; Myotoxin; PLA2; Antivenom; Lipidomics;
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A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas
Keywords: میوتوکسین; Myotoxin; Phospholipase A2; Porthidium ophryomegas;
Screening for target toxins of the antiophidic protein DM64 through a gel-based interactomics approach
Keywords: میوتوکسین; Snake venoms; Myotoxin; Myotoxin inhibitor; Didelphis aurita; Proteomics; Interactomics;
Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii
Keywords: میوتوکسین; Snake venom; Porthidium lansbergii lansbergii; Phospholipase A2; Myotoxin; Cytotoxin
Biochemical and functional studies of ColTx-I, a new myotoxic phospholipase A2 isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
Keywords: میوتوکسین; Snake venom; Phospholipase A2; Myotoxin; Crotalus oreganus lutosus; Biological activities
P9a(Cdt-PLA2) from Crotalus durissus terrificus as good immunogen to be employed in the production of crotalic anti-PLA2 IgG
Keywords: میوتوکسین; Snake venom; Rattlesnake; HPLC-PR; Myotoxin; Neurotoxicity; Antivenom
Production in Escherichia coli, folding, purification and characterization of notexin with wild type sequence and with N-terminal and catalytic site mutations
Keywords: میوتوکسین; Phospholipase A2; Neurotoxin; Snake venom; Protein folding; Notexin; Myotoxin;
A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms
Keywords: میوتوکسین; Snake venom; Myotoxin; Phospholipase A2; Lys49; Inhibitor; Myonecrosis;
Identification of linear B-cell epitopes on myotoxin II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom
Keywords: میوتوکسین; Snake venom; Phospholipase A2; Epitope mapping; Myotoxin; Antibodies; Antivenom;
Snake venom Lys49 myotoxins: From phospholipases A2 to non-enzymatic membrane disruptors
Keywords: میوتوکسین; Myotoxin; Snake venom; Phospholipase A2 homologue; Muscle damage; Myonecrosis; Lys49;
Crystal structure of Bn IV in complex with myristic acid: A Lys49 myotoxic phospholipase A2 from Bothrops neuwiedi venom
Keywords: میوتوکسین; Phospholipase A2; Myristic acid; Myotoxin; Heparin;
Biochemical and pharmacological characterization of PhTX-I a new myotoxic phospholipase A2 isolated from Porthidium hyoprora snake venom
Keywords: میوتوکسین; Snake venom; Porthidium hyoprora; HPLC-PR; D49 PLA2; Myotoxin; Edema-forming activity; Neurotoxicity; Cytotoxicity;
The C-terminal region of a Lys49 myotoxin mediates Ca2+ influx in C2C12 myotubes
Keywords: میوتوکسین; Myotubes; Calcium; Myotoxin; Phospholipase A2 homologue; Lys49; Peptide; Venomp-Acl, C-terminal peptide 115–129 of Agkistrodon contortrix laticinctus myotoxin; p-Scr, scrambled version peptide; PLA2, phospholipase A2; [Ca2+]c, cytosolic calcium ion concen
Generation of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines
Keywords: میوتوکسین; Myotoxin; Immune adjuvant; Adaptive T-cell immunity; Immune microenvironment;
Isolation and characterization of a myotoxin from the venom of Macrovipera lebetina transmediterranea
Keywords: میوتوکسین; Macrovipera lebetina; Metalloproteinase; Myotoxin; Snake venom; Laminin
Isolation and characterization of two new Lys49 PLA2s with heparin neutralizing properties from Bothrops moojeni snake venom
Keywords: میوتوکسین; Bothrops moojeni; de novo sequencing; Heparin neutralization; LMWH; Mass spectrometry; Myotoxin; Lys49 PLA2; UFHACN, acetonitrile; aPTT, activated partial thromboplastin time; aq, aqueous; ATIII, antithrombin III; CT, clotting time; ESI-MS, electrospray i
Identification and characterization of a phospholipase A2 from the venom of the Saw-scaled viper: Novel bactericidal and membrane damaging activities
Keywords: میوتوکسین; Echis carinatus; Myotoxin; Phospholipase A2; Snake venom; Bactericidal activityPLA2, phospholipase A2; EcTx-I, toxin I from Echis carinatus venom; PBS, phosphate buffered saline; HPLC, high pressure liquid chromatography; CFU, colony forming units; MALDI-
Biochemical and biological characterization of a PLA2 from crotoxin complex of Crotalus durissus cumanensis
Keywords: میوتوکسین; Crotalus durissus cumanensis; Crotoxin; Myotoxin; Neurotoxin; Phospholipase A2
Insights of local tissue damage and regeneration induced by BnSP-7, a myotoxin isolated from Bothrops (neuwiedi) pauloensis snake venom
Keywords: میوتوکسین; Bothrops (neuwiedi) pauloensis; Myotoxin; Phospholipase A2; Snake venom; Matrix metalloproteinase; Inflammation; Cytokine; BnSP-7
Structural and functional characterization of brazilitoxins II and III (BbTX-II and -III), two myotoxins from the venom of Bothrops brazili snake
Keywords: میوتوکسین; Snake venom; Bothrops brazili; HPLC-PR; D49 PLA2; K49 PLA2 homologue; Myotoxin; Edema-forming activity and cytotoxicity;
Ability of fucoidan to prevent muscle necrosis induced by snake venom myotoxins: Comparison of high- and low-molecular weight fractions
Keywords: میوتوکسین; Myotoxin; Myonecrosis; Fucoidan; Phospholipase A2; Venom
Structural and functional characterization of myotoxin, Cr-IV 1, a phospholipase A2 D49 from the venom of the snake Calloselasma rhodostoma
Keywords: میوتوکسین; Phospholipase A2; Snake venom; Calloselasma rhodostoma; Myotoxin; Structural and functional characterization
A novel recombinant system for functional expression of myonecrotic snake phospholipase A2 in Escherichia coli using a new fusion affinity tag
Keywords: میوتوکسین; Affinity tag; Chaperones; Congerin; Escherichia coli; Galectin; Microbacterium liquefaciens protease; Myotoxin; Phospholipase A2; Protobothrops flavoviridis; Recombinant expression; Snake venome; Thrombin
A new acidic myotoxic, anti-platelet and prostaglandin I2 inductor phospholipase A2 isolated from Bothrops moojeni snake venom
Keywords: میوتوکسین; Snake venom; Acidic phospholipase A2; Bothrops moojeni; Myotoxin; Platelet aggregation inhibitor; Prostaglandin I2 inductor; Chemical modificationBPB, p-bromophenacyl bromide; BthTXs, Bothrops jararacussu bothropstoxins; BmooTX-I, Bothrops moojeni myotoxi
Crystal structure of a novel myotoxic Arg49 phospholipase A2 homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus
Keywords: میوتوکسین; Zhaoermia mangshanensis; Snake venom; Arg49-phospholipase A2; Lys49-phospholipase A2; Myotoxin; Crystal structure
Purification, characterization and bactericidal activities of basic phospholipase A2 from the venom of Agkistrodon halys (Chinese pallas)
Keywords: میوتوکسین; Bactericidal; Myotoxin; Phospholipase A2; Amino acid sequence; Agkistrodon halys; Cytotoxicity; AgkTx-II; Agkistrodon halys toxin; LPS; lipopolysaccharide; TFA; trifluoroacetic acid; PLA2; phospholipases A2; MALDI-TOF; matrix-assisted laser desorption ion
Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms
Keywords: میوتوکسین; Cationic peptides; Antitumor; Phospholipase A2; Snake venom; Myotoxin;
Structural and functional properties of BaTX, a new Lys49 phospholipase A2 homologue isolated from the venom of the snake Bothrops alternatus
Keywords: میوتوکسین; Phospholipase A2; Lys-49; Neurotoxin; Myotoxin; Snake venom; Bothrops alternatus
Isolation, characterization and molecular cloning of AnMIP, a new α-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae)
Keywords: میوتوکسین; Atropoides nummifer; Phospholipase A2; Myotoxin; Inhibitor; PLI-alpha; Snake venom
Mapping of the structural determinants of artificial and biological membrane damaging activities of a Lys49 phospholipase A2 by scanning alanine mutagenesis
Keywords: میوتوکسین; Bothropstoxin-I; Myotoxin; Bactericide; Myoblast; Liposome; PLA2
Paralyzing and myotoxic effects of a recombinant bothropstoxin-I (BthTX-I) on mouse neuromuscular preparations
Keywords: میوتوکسین; Myotoxin; Phospholipase A2; Muscle damage; Ultrastructure
Influence of temperature upon paralyzing and myotoxic effects of bothropstoxin-I on mouse neuromuscular preparations
Keywords: میوتوکسین; Bothropstoxin-I; Myonecrosis; Muscle paralysis; Myotoxin; Phospholipase A2; Lys49;
Myotoxic and cytolytic activities of dimeric Lys49 phospholipase A2 homologues are reduced, but not abolished, by a pH-induced dissociation
Keywords: میوتوکسین; Snake venom; Myotoxin; Phospholipase A2; Dimeric protein; Muscle;
Isolation and characterisation of acanmyotoxin-2 and acanmyotoxin-3, myotoxins from the venom of the death adder Acanthophis sp. Seram
Keywords: میوتوکسین; Death adder; Acanthophis; Acanmyotoxin; Myotoxin; Chick biventer cervicis nerve-muscle; Phospholipase A2; Venom;
Purification of a myotoxin from the toadfish Thalassophryne maculosa (Günter) venom
Keywords: میوتوکسین; Calcium conductance; Toadfish venom; myotoxin; Skeletal muscle; Thalassophryne;
New view on crotamine, a small basic polypeptide myotoxin from South American rattlesnake venom
Keywords: میوتوکسین; Crotalus; Myotoxin; Crotamine; Cationic peptide; Structure; Cell penetrating peptide; Biological activity; Gene; Paralogous gene; Toxin;
Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: Isolation of 4-nerolidylcatechol as active principle
Keywords: میوتوکسین; Piper umbellatum; Piper peltatum; Piperaceae; 4-Nerolidylcatechol; Myotoxin; Phospholipase A2; Snake venoms; Bothrops;
A predominant role for hydrogen bonding in the stability of the homodimer of bothropstoxin-I, A lysine 49-phospholipase A2
Keywords: میوتوکسین; Mutagenesis; Myotoxin; Membrane damage; Dimer interface; BthTx-I; a Lys49 phospholipase A2 isolated from B. jararacussu venom; CD; circular dichroism; farUVCD; circular dichroism spectra in the far ultraviolet region; GdnHCl; guanidinium hydrochloride; HE
Renal and antibacterial effects induced by myotoxin I and II isolated from Bothrops jararacussu venom
Keywords: میوتوکسین; Bothrops jararacussu; Myotoxin; Renal; Antibacterial activity; Phospholipase A2;