Keywords: N- ترمینال; N-terminus; amino-terminus; C-terminu; scarboxy-terminus; cDNA; complementary deoxyribonucleic acid; CHO; Chinese hamster oocyte; cAMP; cyclic adenosine monophosphate; ECL; extracellular loop; EC50; half maximal effective concentration; HEK cells; human e
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Keywords: N- ترمینال; ÎCN; calcineurin proteolytic fragment; AD; Alzheimer's disease; AID; autoinhibitory domain; IHC; immunohistochemistry; Aβ; beta-amyloid; SMTG; superior and middle temporal gyri; NeuN; neuronal-specific nuclear protein; DAB; 3,3â²-diaminobenzidine; CaM;
Copper induces structural changes in N-terminus of human prion protein
Keywords: N- ترمینال; Prion; N-terminus; Structure; Copper;
Functional characterization of the dual allatostatin-A receptors in mosquitoes
Keywords: N- ترمینال; AstA; allatostatin-A; N-terminus; amino-terminus; AstAR; AstA receptor; C-terminus; carboxy-terminus; cDNA; complementary deoxyribonucleic acid; CHO; chinese hamster oocyte; ECL; extracellular loop; EC50; Half maximal effective concentration; ICL; intrace
Positive effect of strong acidity on the twist of Aβ42 fibrils and the counteraction of Aβ42 N-terminus
Keywords: N- ترمینال; Aβ42 fibril; Protonation; Twist angle; N-terminus; Amyloid material;
Relevance of N-terminal residues for amyloid-β binding to platelet integrin αIIbβ3, integrin outside-in signaling and amyloid-β fibril formation
Keywords: N- ترمینال; Platelets; Alzheimer's disease; Clusterin; Amyloid-β; Cerebral amyloid angiopathy; N-terminus;
ReviewSoxE factors: Transcriptional regulators of neural differentiation and nervous system development
Keywords: N- ترمینال; CNS; central nervous system; C-terminus; carboxyterminus; Hdac; histone deacetylase; HMG; high mobility group; N-terminus; aminoterminus; NC; neural crest; OPC; oligodendrocyte precursor; pMN; precursor to motor neuron; PNS; peripheral nervous system; PCW
The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era
Keywords: N- ترمینال; GPCR; G protein-coupled receptor; N-terminus; Proteolysis; Signalling;
Functional mapping of the N-terminal arginine cluster and C-terminal acidic residues of Kir6.2 channel fused to a G protein-coupled receptor
Keywords: N- ترمینال; ACh; acetylcholine; atm; atmosphere; C-ter; C-terminus; CTD; cytoplasmic domain; D2; D2L dopaminergic receptor; GPCR; G protein-coupled receptor; ICCR; ion channel-coupled receptor; N-ter; N-terminus; TEVC; two-electrode voltage-clamp; TMD; transmembrane
The voltage-sensitive dye RH421 detects a Na+,K+-ATPase conformational change at the membrane surface
Keywords: N- ترمینال; RH421 fluorescence; Na+,K+-ATPase; Stopped-flow kinetics; Molecular dynamics; N-terminus; Phosphorylation;
The long N-terminus of the human monocarboxylate transporter 8 is a target of ubiquitin-dependent proteasomal degradation which regulates protein expression and oligomerization capacity
Keywords: N- ترمینال; MCT8; N-terminus; Ubiquitination; Degradation; Oligomerizationaa, amino acid; AHDS, Allan-Herndon-Dudley Syndrome; GFP, green fluorescent protein; MCT8, monocarboxylate transporter 8; MFS, major facilitator superfamily; reverse T3, 3,3′,5′-tri-iodothyroni
The N-terminus of VDAC: Structure, mutational analysis, and a potential role in regulating barrel shape
Keywords: N- ترمینال; Voltage-dependent anion selective channel; VDAC; Mitochondrial porin; N-terminus; Voltage gating; β-Barrel
RNF138 interacts with RAD51D and is required for DNA interstrand crosslink repair and maintaining chromosome integrity
Keywords: N- ترمینال; HR; homologous recombination; CFA; colony forming assay; NT; N-terminus; ssDNA; single-stranded DNA; ICL; interstrand crosslink; DSB; double-strand break; MEF; mouse embryo fibroblasts; MMC; mitomycin C; MMS; methyl methanesulfonate; PTM; post-translation
A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant
Keywords: N- ترمینال; DRG; dorsal root ganglion; EA2; Episodic ataxia 2; FHM1; familial hemiplegic migraine type 1; SCA6; spinocerebellar ataxia type 6; TAT; transactivator of transcription; Episodic ataxia-2; P/Q-type calcium channel; Dominant negative suppression; N-terminus
A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights
Keywords: N- ترمینال; SDF-1; stromal cell-derived factor 1; GPCR; G protein-coupled receptor; CNS; central nervous system; NS; nervous system; DRG; dorsal root ganglion; OPC; oligodendrocyte precursor cell; MS; multiple sclerosis; PDB; Protein Data Bank; TM; transmembrane; EL;
SCN4A mutation as modifying factor of Myotonic Dystrophy Type 2 phenotype
Keywords: N- ترمینال; Myotonic dystrophy type 2; Myotonia; SCN4A; N-terminus;
Subcellular localization and internalization of the vasopressin V1B receptor
Keywords: N- ترمینال; AVP; arginine-vasopressin; C-terminus; carboxyl-terminus; CHO; Chinese hamster ovary; DAB; 3,3â²-diaminobenzidine; DMEM; Dulbecco's modified Eagle's medium; GFP; green fluorescent protein; GPCRs; G-protein coupled receptors; HEK; human embryonic kidn
Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom
Keywords: N- ترمینال; ASIC; acid-sensing ion channel; CNF; conorfamide; C-terminus; carboxyl terminus; [Ca2Â +]i; cytosolic calcium ion concentration; DRG; dorsal root ganglion; FaNaC; FMRF-amide-gated Na+ channel; GPCR; G-protein-coupled receptor; IC; intracranial; MeCN; acet
Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae
Keywords: N- ترمینال; RPA; N-terminus; Phosphorylation; DNA damage response;
Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death
Keywords: N- ترمینال; AkoMEFS; Apaf1 knock-out mice; Apaf1; apoptotic protease-activating factor 1; Cyt c; cytochrome c; DMEM; Dulbecco's Modified Eagle Medium; DOXO; doxorubicin; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EGFP; enhanced green fluorescent pr
Interplay of DNA damage and cell cycle signaling at the level of human replication protein A
Keywords: N- ترمینال; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; ATRIP; ATR-interacting protein; CDK; cyclin-dependent kinase; CIP; calf intestinal phosphatase; DDR; DNA damage response; DNA-PKcs; D
Expression and purification of recombinant calpain-derived N-terminal peptides from glycine transporter GlyT2
Keywords: N- ترمینال; Glycine; Transporter; GlyT2; Calpain; N-terminus; Purification;
Experimental determination of organelle targeting-peptide cleavage sites using transient expression of green fluorescent protein translational fusions
Keywords: N- ترمینال; Mitochondria; Chloroplast; Plastid; GFP; Import; Targeting peptide; Transit peptide; Signal peptide; N-terminus; Edman; Mass spectrometry; Transfection;
The use of plasma-activated covalent attachment of early domains of tropoelastin to enhance vascular compatibility of surfaces
Keywords: N- ترمینال; Tropoelastin; N-terminus; Stent; Endothelial cell; Plasma surface modification; Covalent immobilization
N-terminal mono-PEGylation of growth hormone antagonist: Correlation of PEG size and pharmacodynamic behavior
Keywords: N- ترمینال; PEGylation; Growth hormone antagonist; N-terminus; Polyethylene glycol; Acromegaly
Deletion combined with saturation mutagenesis of N-terminal residues in transglutaminase from Streptomyces hygroscopicus results in enhanced activity and thermostability
Keywords: N- ترمینال; Transglutaminase; Specific activity; Thermostability; N-terminus; Saturation mutagenesis;
The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity
Keywords: N- ترمینال; TDP-43; DNA/RNA binding; Oligomerization; Neurodegenerative disease; N-terminus;
Soil-mediated prion transmission: Is local soil-type a key determinant of prion disease incidence?
Keywords: N- ترمینال; PrP protein; Transmissible spongiform encephalopathy; N-terminus; BSE; CJD; Fate
Upstream start codon in segment 4 of North American H2 avian influenza A viruses
Keywords: N- ترمینال; FL; firefly luciferase; HA; hemagglutinin; NA; neuraminidase; N-ter; N-terminus; RL; Renilla luciferase; UTR; untranslated region; Segment 4; Influenza A virus; Hemagglutinin; Start codon; Kozak consensus; Untranslated region;
Competing interactions for antimicrobial selectivity based on charge complementarity
Keywords: N- ترمینال; POPG; palmitoyl-oleoyl-phosphatidyl-glycerol; POPC; palmitoyl-oleoyl-phosphatidyl-choline; MD; molecular dynamics; AMPs; antimicrobial peptides; PG; phosphatidyl-glycerol; PE; phosphatidyl-ethanolamine; PC; phosphatidyl-choline; DPPC; diplamitoyl-PC; DPPG
Five mutations in N-terminus confer thermostability on mesophilic xylanase
Keywords: N- ترمینال; Xylanase; Thermostability; N-terminus; Chimera; Mutant
A novel functional element in the N-terminal region of Arum concinnatum alternative oxidase is indispensable for catalytic activity of the enzyme in HeLa cells
Keywords: N- ترمینال; Alternative oxidase; Arum lily; Thermogenesis; Inactive isoform; N-terminus; Loss of function
Actinoporins from the sea anemones, tropical Radianthus macrodactylus and northern Oulactis orientalis: Comparative analysis of structure–function relationships
Keywords: N- ترمینال; Radianthus macrodactylus; Oulactis orientalis; Actinoporin; Amino acid sequence; Hemolytic activity; Homology model; N-Terminus; RGD motif; POC binding site; Phylogenetic analysis; Structure–function relationshipsALPs, actinoporin-like proteins; SM, sphin
Structure and function of G protein-coupled receptors using NMR spectroscopy
Keywords: N- ترمینال; Membrane proteins; Magic angle spinning; Structure; CL; cytoplasmic loop; cryo-EM; cryogenic electron microscopy; C-terminus; carboxy terminus; DARR; dipolar-assisted rotational resonance; DDM; dodecyl-β-d-maltoside; DNA; deoxyribonucleic acid; DNP; dyna
E. coli cardiolipin synthase: Function of N-terminal conserved residues
Keywords: N- ترمینال; Cardiolipin; CL synthase; N-terminus; Conserved residue; Processing; Mutagenesis
Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm
Keywords: N- ترمینال; Binding; DNA; Minor-groove; N-terminus; Polyamide;
Functional comparison of full-length and N-terminal-truncated octopamine transporters from Lepidoptera
Keywords: N- ترمینال; Octopamine; Transporter; Moth; Full-length; N-terminus; Trichoplusia ni; Ostrinia nubilalis; Pieris rapae
Macromolecular substrate affinity for free factor VIIa is independent of a buried protease domain N-terminus
Keywords: N- ترمینال; Factor VIIa; Activation pocket; N-terminus; N-terminal insertion; Zymogen-like; Substrate affinity
N-terminal peptides from unprocessed prion proteins enter cells by macropinocytosis
Keywords: N- ترمینال; Prion protein; N-terminus; Cell-penetrating peptide; Endocytosis; Macropinocytosis; Proteoglycan
The N-terminal cleavage site of PrPSc from BSE differs from that of PrPSc from scrapie
Keywords: N- ترمینال; Prion; Scrapie; BSE; PrPSc; PrPcore; N-terminus;
Improvement of the thermostability and catalytic activity of a mesophilic family 11 xylanase by N-terminus replacement
Keywords: N- ترمینال; Xylanase; Thermostability; Catalytic activity; N-terminus; Pichia pastoris;
Structural analysis and expression profile of a novel gene on chromosome 5q23 encoding a Golgi-associated protein with six splice variants, and involved within the 5q deletion of a Ph(â) CML patient
Keywords: N- ترمینال; MDS; myelodysplastic syndromes; IL3; interleukin 3; TCF-1; T-cell transcription factor 1; GM-CSF; granulocyte macrophage-colony stimulating factor; IRF1; interferon regulatory factor 1; cDNA; complementary deoxuribonucleic acid; YAC; yeast artificial chro