Keywords: N-استیل سیستئین; Toxicant mixture; Acrylamide; Additive; Synergistic; Concentration addition; Environmental toxicologyMVK, methylvinyl ketone; EA, 2-ethylacrolein; MA, methyl acrylate; ACR, acrylamide; HNE, 4-Hydroxy-2-nonenal; NAC, N-acetylcysteine; GSH, glutathione; HSA
مقالات ISI N-استیل سیستئین (ترجمه نشده)
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Keywords: N-استیل سیستئین; NAC; Alcoholism; Cirrhosis; SteroidAH, alcoholic hepatitis; AST, aspartate aminotransferase; DF, discriminant function; G-CSF, granulocyte colony–stimulating factor; MELD, model for end-stage liver disease; NAC, N-acetylcysteine; STOPAH, steroids or pento
Keywords: N-استیل سیستئین; APN, adiponectin; HCC, hepatocellular carcinoma; JNK, C-Jun N-terminal kinase; Trx, thioredoxin; NAC, N-acetylcysteine; AMPK, 5′-adenosine monophosphate-activated protein kinase; ROS, reactive oxygen species; ASK1, apoptosis signal-regulating kinase 1; PC
Keywords: N-استیل سیستئین; gluc, glucuronide; sulf, sulfate; NAPQI, N-acetyl-p-benzoquinone imine; glut, glutathione; cys, cysteine; NAC, N-acetylcysteine; LC–MS/MS, liquid chromatography–tandem mass spectrometry; HPLC–ESI–MS/MS, high-performance liquid chromatography–electrospray
Keywords: N-استیل سیستئین; EMT, Epithelial–mesenchymal transition; BLM, Bleomycin; NAC, N-acetylcysteine; BMZ, Basement membrane zone; ROS, Reactive oxygen species; MDA, MalondialdehydeBleomycin; Epithelial–mesenchymal transition; N-acetylcysteine; Oxidative stress; Skin fibrosis;
Keywords: N-استیل سیستئین; BIS-11, Barratt Impulsiveness Scale; dACC, dorsal anterior cingulate cortex; NAC, N-acetylcysteine; SUD, substance use disorderImpulsivity; Non-adherence; Abstinence; Cannabis; Marijuana; Adolescent; Youth; Pharmacotherapy; N-acetylcysteine
Keywords: N-استیل سیستئین; Sb, Antimony; NAC, N-acetylcysteine; Nrf2, NF-E2-related factor 2; ROS, Reactive oxygen species; Sb2O3, Antimony trioxide; TBHQ, Tertiary butylhydroquinoneAntimony; Apoptosis; Nrf2; Gadd45b; ROS
Keywords: N-استیل سیستئین; NAC, N-acetylcysteine; PN, pyramidal neuron; PNN, perineuronal net; PVIs, parvalbumin interneurons; RNS, reactive nitrogen species; ROS, reactive oxygen speciesParvalbumin interneurons; Oligodendrocytes; Myelination; N-acetylcysteine; Development; Oxidati
Keywords: N-استیل سیستئین; Cisplatin; Resveratrol; Malignant mesothelioma; Apoptosis; Autophagy; ChemoresistanceMM, malignant mesothelioma; CDDP/RSV, combination of cisplatin and resveratrol; NAC, N-acetylcysteine; ROS, reactive oxygen species; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5
Enhanced inhibition of bacterial biofilm formation and reduced leukocyte toxicity by chloramphenicol:β-cyclodextrin:N-acetylcysteine complex
Keywords: N-استیل سیستئین; CP, chloramphenicol; NAC, N-acetylcysteine; β-CD, β-cyclodextrin; CTC, chloramphenicol ternary complexes; FD, freeze-drying; PM, physical mixture; FT-IR, fourier transform infrared spectroscopy; SEM, scanning electron microscopy; DSC, differential scannin
Effect of inhaled N-acetylcysteine monotherapy on lung function and redox balance in idiopathic pulmonary fibrosis
Keywords: N-استیل سیستئین; 6MWD, 6-min walk distance; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; BAL, Bronchoalveolar lavage; FVC, vital capacity; GSH, Reduced levels of glutathione; GSSG, Oxidized glutathione; IPF, Idiopathic pulmonary fibrosis; NAC, N-acetylcysteine; ROS, Reactive oxyg
N-acetylcysteine relieves oxidative stress and protects hippocampus of rat from radiation-induced apoptosis by inhibiting caspase-3
Keywords: N-استیل سیستئین; NAC, N-acetylcysteine; Caspase, cysteinyl aspartate specific proteinase; ROS, reactive oxygen species; IR, irradiation; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end-labeling; GSH, glutathione; CT, cycle threshold; DCF, dichlorofluoresceinN-a
Oxidative DNA damage induced by di-(2-ethylhexyl) phthalate in HEK-293 cell line
Keywords: N-استیل سیستئین; DEHP, di-(2-ethylhexyl) phthalate; HEK-293, human embryonic kidney cell line 293; GSH, glutathione; BSO, buthionine-(S,R)-sulfoximine; NAC, N-acetylcysteine; MEHP, mono(2-ethylhexyl) phthalate; SCGE, single-cell gel electrophoresis; ROS, reactive oxygen s
NEFAs activate the oxidative stress-mediated NF-κB signaling pathway to induce inflammatory response in calf hepatocytes
Keywords: N-استیل سیستئین; NEFAs, nonesterified fatty acids; PDTC, pyrrolidine dithiocarbamate; NAC, N-acetylcysteine; NEB, negative energy balance; ROS, reactive oxygen species; MDA, malonaldehyde; GSH-Px, glutathione peroxidase; SOD, superoxide dismutase; CAT, catalase; SFA, satu
Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione
Keywords: N-استیل سیستئین; GCS, glucosylceramide synthase; GSH, glutathione; NAC, N-acetylcysteine; nSMase, neutral sphingomyelinase; PMSF, phenylmethylsulfonyl fluoride; ROS, reactive oxygen species; SMS, sphingomyelin synthaseCurcumin; Ceramide; Bcl proteins; Glutathione; Caspase
Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells
Keywords: N-استیل سیستئین; STAT3, signal transducer and activator of transcription 3; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor receptor; JAK, Janus-activated kinases; DCF-DA, 2,7-dichlorofluorescein diacetate; NAC, N-acetylcysteine; GSH, glutath
S-Allylmercapto-N-acetylcysteine (ASSNAC) protects cultured nerve cells from oxidative stress and attenuates experimental autoimmune encephalomyelitis
Keywords: N-استیل سیستئین; ASSNAC, S-allylmercapto-N-acetylcysteine; Nrf2, nuclear factor erythroid-derived 2-related factor 2; tBuOOH, tert-butyl hydroperoxide; EAE, experimental autoimmune encephalomyelitis; ROS, reactive oxygen species; NAC, N-acetylcysteine; SSA, 5-sulfosalicyl
Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs
Keywords: N-استیل سیستئین; ECs, endothelial cells; HUVECs, human umbilical vein endothelial cells; GSI, γ-secretase inhibitor; Nox, NADPH oxidase; PTPs, phosphotyrosine phosphotases; DPI, diphenyl-iodide; NAC, N-acetylcysteine; DMSO, dimethyl sulfoxideNotch signaling; ROS; HUVECs;
HPLC separation of human serum albumin isoforms based on their isoelectric points
Keywords: N-استیل سیستئین; EPGC, external pH gradient chromatofocusing; AEHIC, anion exchange-hydrophobic interaction chromatography; DTNB, 5,5′-dithiobis-(2-nitrobenzoate); DEAE, diethylaminoethyl; pI, isoelectric point; GSH, reduced glutathione; NAC, N-acetylcysteine; HSA, human
Docosahexaenoic acid decreases TNF-α-induced lectin-like oxidized low-density lipoprotein receptor-1 expression in THP-1 cells
Keywords: N-استیل سیستئین; Ac-LDL, acetylated LDL; DHA, docosahexaenoic acid; ROS, reactive oxygen species; NAC, N-acetylcysteine; LFA1, lymphocyte function-associated antigen1; LOX-1, lectin-like oxidized LDL receptor-1; TNF-α, tumor necrosis factor alpha; VAL4, very late antigen-
Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity
Keywords: N-استیل سیستئین; DPI, diphenyleneiodonium; NAC, N-acetylcysteine; H2O2, hydrogen peroxide; LDH, lactate dehydrogenase; siRNA, small interfering RNAs; AA, arachidonic acid; LOX, lipoxygenase; COX, cyclooxygenase; PLA2, phospholipase A2; LTB4, leukotriene B4; 12(S)-HETE, 12
Glutathione initiates the development of Dictyostelium discoideum through the regulation of YakA
Keywords: N-استیل سیستئین; GSH, reduced glutathione; GSSG, oxidized glutathione; PSF, prestarvation factor; CMF, conditioned medium factor; cAR1, cAMP receptor; ACA, adenylyl cyclase; PKA, protein kinase A; DTT, dithiothreitol; NAC, N-acetylcysteine; mBBr, monobromobimane; NEM, N-e
Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways
Keywords: N-استیل سیستئین; ROS, reactive oxygen species; MAPKs, mitogen-activated protein kinases; JNK, c-Jun N-terminal kinase; ERK, extracellular signal-related kinase; Nrf2, nuclear-factor-E2-related factor 2; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; ER stress,
Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd2+-induced apoptosis
Keywords: N-استیل سیستئین; NAC, N-acetylcysteine; BAEC, bovine aortic endothelial cell; BSO, buthionine sulfoximine; DUSP4/MKP2, dual-specificity phosphatase 4 or MAPK phosphatase 2; ED, endothelial dysfunction; eNOS, endothelial nitric oxide synthase; EPR, electron paramagnetic re
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells
Keywords: N-استیل سیستئین; BSO, l-buthionine-sulfoximine; CSC, cancer stem cell; DCF-DA, 2′,7′-dichlorofluorescein diacetate; GFAP, glial fibrillary acidic protein; GIC, glioma-initiating cell; GSH, glutathione; NAC, N-acetylcysteine; ROS, reactive oxygen species
ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma
Keywords: N-استیل سیستئین; AMPK, adenosine monophosphate-activated protein kinase; Cur, curcumin; GSH, glutathione; LKB1, liver kinase B1; mTOR, mammalian target of rapamycin; NAC, N-acetylcysteine; p70S6K, p70S6 kinase; Par-4, prostate apoptosis response 4; PARP, poly (ADP-ribose)
Bridging the gap between old and new concepts in drug-induced liver injury
Keywords: N-استیل سیستئین; APAP, acetaminophen; 2-APB, 2-aminoethoxydiphenyl borate; Cx32, connexin 32; CYP2E1, cytochrome P450 2E1; DILI, drug-induced liver injury; MPT, membrane permeability transition; NAC, N-acetylcysteine; NAPQI, N-acetyl-p-benzoquinone imine; OXPHOS, oxidativ
Cadmium(Cd)-induced oxidative stress down-regulates the gene expression of DNA mismatch recognition proteins MutS homolog 2 (MSH2) and MSH6 in zebrafish (Danio rerio) embryos
Keywords: N-استیل سیستئین; BHT, butylhydroxyltoluene; Cd, cadmium; hpf, hours post fertilization; MMR, DNA mismatch repair; MSH2, MutS homolog 2; MSH6, MutS homolog 6; NAC, N-acetylcysteine; PAGE, polyacrylamide gel electrophoresis; ROS, reactive oxygen speciesCadmium; DNA mismatch
Gentamicin caused renal injury deeply related to methylglyoxal and Nɛ-(carboxyethyl)lysine (CEL)
Keywords: N-استیل سیستئین; GM, gentamicin; GN, gentamicin nephropathy; AG, Aminoglycoside; AN, Aminoglycoside nephropathy; MGO, methylglyoxal; CEL, Nɛ-(carboxyethyl)lysine; AGEs, advanced glycation end products; DM, diabetes mellitus; GSH, glutathione; NAC, N-acetylcysteine; Ucr, u
Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance
Keywords: N-استیل سیستئین; CF, Control-fed; MR, Methionine restriction/restricted; NAC, N-acetylcysteine; SAA, Sulfur amino acids; SCD1, Stearoyl-coenzyme A desaturase-1; tCys, Total cysteine; tGSH, Total glutathione; tHcy, Total homocysteineGlutathione; Cysteine; Sulfur amino acid
Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways
Keywords: N-استیل سیستئین; Rhizoma Curcumae Longae; bisdemethoxycurcumin (BDMC); reactive oxidative species (ROS); breast cancerΔψm, mitochondrial membrane potential; BDMC, bisdemethoxycurcumin; NAC, N-acetylcysteine; Rb, retinoblastoma protein; ROS, reactive oxidative species
Characterizing low dose and dose rate effects in rodent and human neural stem cells exposed to proton and gamma irradiation
Keywords: N-استیل سیستئین; ROS, Reactive oxygen species; RNS, Reactive nitrogen species; NAC, N-acetylcysteine; CM-H2DCFDA (or CM), 5-(and 6-) Chloromethyl-2,7-dichlorodihydrofluorescein diacetate; DAF, 4-Amino-5methylamino-2′,7′-difluorescein diacetate; MS, Mitosox; GCR, Galactic
Adhesion of quantum dots-induced membrane damage of Escherichia coli
Keywords: N-استیل سیستئین; MPA, mercaptopropionic acid; NAC, N-acetylcysteine; GSH, glutathione; QDs, quantum dotsCdTe QDs; Adhesion; Membrane fluidity; Membrane permeability; Toxicity; Microcalorimetric methods
Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursorcells
Keywords: N-استیل سیستئین; ROS, reactive oxygen species; O2•−, superoxide; Sod2, manganese superoxide dismutase; FECH, ferrochelatase; NO•, nitric oxide; IRE, iron-response element; DHE, dihydroethidium; TBARS, thiobarbituric acid-reactive substances; NAC, N-acetylcysteine; CBC, co
Developmental neuroinflammation and schizophrenia
Keywords: N-استیل سیستئین; 3-OHKY, 3-hydroxykynurenine; CNS, central nervous system; EGF, epidermal growth factor; FGF, fibroblast growth factor; GABA, γ-aminobutyric acid; IFN, interferon; IL, interleukin; LPS, lipopolysaccharide; NAC, N-acetylcysteine; polyI:C, polyriboinosinic–p
Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process
Keywords: N-استیل سیستئین; ASC, ascorbate acid; Fv/Fm, the ratio of the variable fluorescence to the maximal fluorescence; GPS, glyphosate; MCPA-Na, 2-methyl-4-chlorophenoxyacetic acid; MDA, malondialdehyde; NAC, N-acetylcysteine; ROS, reactive oxygen species; SOD, superoxide dismu
Contemporary Use and Effectiveness of N-Acetylcysteine in Preventing Contrast-Induced Nephropathy Among Patients Undergoing Percutaneous Coronary Intervention
Keywords: N-استیل سیستئین; contrast-induced nephropathy; N-acetylcysteine; percutaneous coronary interventionCIN, contrast-induced nephropathy; GFR, glomerular filtration rate; NAC, N-acetylcysteine; PCI, percutaneous coronary intervention
Titanium dioxide particles phosphorylate histone H2AX independent of ROS production
Keywords: N-استیل سیستئین; BSA, bovine serum albumin; BSFGE, biased sinusoidal field gel electrophoresis; DCFH-DA, 6-carboxy-2,7′-diclorodihydrofluorescein diacetate, di(acetoxy ester); DSBs, double strand breaks; FCM, flow cytometer; NAC, N-acetylcysteine; FS, forward-scattered li
Regulation of prostate cancer cell invasion by modulation of extra- and intracellular redox balance
Keywords: N-استیل سیستئین; CySS, cystine; FITC, fluorescein isothiocyanate; DTT, dithiothreitol; GSH, glutathione; GSSG, glutathione disulfide; IAA, iodoacetic acid; MMP, matrix metalloproteinase; NAC, N-acetylcysteine; •NO, nitric oxide; NOX1, NADPH oxidase 1; PrEC, normal prostat
Antioxidant treatment reduces blast-induced cochlear damage and hearing loss
Keywords: N-استیل سیستئین; ABR, auditory brainstem response; DPOAE, distortion product otoacoustic emission; SNHL, sensorineural hearing loss; NAC, N-acetylcysteine; HPN-07, 2,4-disulfonyl α-phenyl tertiary butyl nitrone; OHC, outer hair cell; IHC, inner hair cell; SPL, sound press
Spectroscopic studies on the interactions between CdTe quantum dots coated with different ligands and human serum albumin
Keywords: N-استیل سیستئین; MPA, mercaptopropionic acid; NAC, N-acetylcysteine; GSH, glutathione; HSA, human serum albumin; QDs, quantum dotsCdTe quantum dots; Human serum albumin; Spectroscopic methods; Interaction; Thermodynamics
Involvement of oxidative stress-induced ERK/JNK activation in the Cu2+/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic β-cells
Keywords: N-استیل سیستئین; DM, diabetes mellitus; PDTC, pyrrolidine dithiocarbamate; LPO, lipid peroxidation; GSH, glutathione; PARP, poly (ADP-ribose) polymerase; NAC, N-acetylcysteine; MAPKs, mitogen-activated protein kinases; ERK, extracellular signal-regulated kinases; JNK, c-j
Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver
Keywords: N-استیل سیستئین; CYP2E1, Cytochrome P4502E1; WT, Wild-type; KO, Knockout; NAC, N-acetylcysteine; TBARS, Thiobarbituric acid reactive substances; GSH, Glutathione; 4EBP1, 4E-binding protein-1; SREBP, Sterol regulatory element-binding proteins; PPAR, Peroxisome proliferator
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo
Keywords: N-استیل سیستئین; APAP, acetaminophen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GSH, glutathione; GSSG, glutathione disulfide; MDA, malondi-aldehyde; NAC, N-acetylcysteine; MALDI-TOF/TOF-MS/MS, matrix-assisted laser desorption/ionization time of flig
TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2
Keywords: N-استیل سیستئین; DPI, diphenyleneiodonium; IL-6, interleukin-6; ILO, Ilomastat; MMP, matrix metalloproteinase; NAC, N-acetylcysteine; NADPH, nicotinamide adenine dinucleotide phosphate-oxidase; NF-κB, nuclear factor-kappa beta; NSC, NSC23766; PDTC, pyrridoline dithiocarba
Intensive Care of the Adult Patient With Congenital Heart Disease
Keywords: N-استیل سیستئین; CHD, congenital heart disease; CICU, cardiac intensive care unit; CPR, cardiopulmonary resuscitation; GFR, glomerular filtration rate; ICU, intensive care unit; LV, left ventricular; NAC, n-acetylcysteine; VAD, ventricular assist device
Suppression of human prostate cancer PC-3 cell growth by N-acetylcysteine involves over-expression of Cyr61
Keywords: N-استیل سیستئین; NAC, N-acetylcysteine; PI3K, phosphoinositide 3-kinase; PC, prostate cancer; ROS, reactive oxygen species; CHX, cycloheximide; DCF-DA, 2′,7′-Dichlorofluorescin diacetate; ECL, enhanced chemiluminescenceN-acetylcysteine; Cyr61; Prostate cancers; ROS; Antio
Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization
Keywords: N-استیل سیستئین; CSC, cancer stem cell; MMP, mitochondrial membrane potential; ROS, reactive oxygen species; MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; NAC, N-acetylcysteine; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; DiOC6, 3,3-dihexyl
Glutathione modulates the toxicity of, but is not a biologically relevant reductant for, the Pseudomonas aeruginosa redox toxin pyocyanin
Keywords: N-استیل سیستئین; CF, cystic fibrosis; EPR, electron paramagnetic resonance; GSH, glutathione; GSSG, glutathione disulfide; HDF, human dermal fibroblast; NAC, N-acetylcysteine; NADPH, nicotinamide adenine dinucleotide phosphate (reduced); PD, population doubling; ROS, reac
p38 Mitogen-activated protein kinase (p38 MAPK) and NADPH Oxidase (NOX) are cytoprotective determinants in the trophozoite-induced apoptosis of peripheral blood mononuclear cells
Keywords: N-استیل سیستئین; 7-AAD, 7-aminoactinomycin D; AIF, apoptosis-inducing factor; AMC, Aminomethylcoumarin; DPI, diphenylene iodonium chloride; MAPK, mitogen-activated protein kinase; NAC, N-acetylcysteine; NBT, Nitroblue Tetrazolium; NBTred, Reduced Nitroblue Tetrazolium (Fo