
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase – The importance of accommodating the active site water
Keywords: NCS، تقارن غیر کریستالوگرافی; BTP, 1,3-bis(tris(hydroxymethyl)methylamino)propane; DAH7PS, 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; E4P, d-erythrose 4-phosphate; EDTA, ethylenediaminetetraacetic acid; LE, ligand efficiency; NCS, non-crystallographic symmetry; NMR, nuclear