دانلود مقالات ISI درباره نورورتین + ترجمه فارسی

تأثیر کاربرد فاکتور نوروتروپیک درون مغزی بر علائم حرکتی در بیماری پارکینسون: بررسی منظم و متاآنالیز

Effects of intracerebral neurotrophic factor application on motor symptoms in Parkinson's disease: A systematic review and meta-analysis

Keywords: نورورتین; Parkinson's disease; Neurotrophic therapy; Clinical trials; Systematic review/meta-analysis; Neurotrophic factors; CI; confidence interval; DA; dopaminergic/dopamine; GDNF; glial cell line-derived neurotrophic factor; NTF; neurotrophic factor; NTN; neurtu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

تجزیه و تحلیل ایمونوهیستولوژیک نورتورین و گیرنده های آن در حلقه انسانی

Immunohistological analysis of neurturin and its receptors in human cochlea

Keywords: نورورتین; Human cochlea; Spiral ganglion neuron; GDNF family ligand; Neurturin; cRet; GFRα-1; GFRα-2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

اثر کمبود نوروتین بر غربالگری کولینرژیک و کاتچولامینرژیک چشم چشمی

Effect of neurturin deficiency on cholinergic and catecholaminergic innervation of the murine eye

Keywords: نورورتین; neurturin; iris; ciliary body; retina; dopamine; amacrine cells; parasympathetic; sympathetic; BSA; bovine serum albumin; ChAT; choline acetyltransferase; GDNF; glial cell-line derived neurotrophic factor; GFRα2; GDNF family receptor α2; H&E; hematoxyli

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

ژن درمان آنتی اکسیدان در برابر مرگ سلول های عصبی

Antioxidant gene therapy against neuronal cell death

Keywords: نورورتین; Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ΔΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2014 سفارش ترجمه

Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation

Keywords: نورورتین; Skeletal muscle; PGC-1α; Neurturin; Motor neuron; Myokine;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Role of RET protein-tyrosine kinase inhibitors in the treatment RET-driven thyroid and lung cancers

Keywords: نورورتین; ARTN; artemin; AS; activation segment; CD; cadherin-like domain; CDK; cyclin-dependent protein kinase; CL; catalytic loop; CS or C-spine; catalytic spine; CTT; carboxyterminal tail; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor re

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2018 سفارش ترجمه

ReviewGene therapy for Parkinson's disease: Disease modification by GDNF family of ligands

Keywords: نورورتین; Adeno-associated virus; AAV; Viral vectors; Non-human primates; GDNF; Neurturin; Neurotrophic factors; Dopamine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Translational research for Parkinson׳s disease: The value of pre-clinical primate models

Keywords: نورورتین; PD; Parkinson׳s disease; SNpc; substantia nigra pars compacta; L-DOPA; Levodopa, 3,4-dihydroxyphenylalanine; 6OHDA; 6-hydroxydopamine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AADC; L-aromatic amino acid decarboxylase; TH; tyrosine hydroxylase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-l-lysine dendrons

Keywords: نورورتین; Cell-penetrating peptides; Poly-l-lysine dendron; DNA delivery; Gene therapy; Neurturin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)

Keywords: نورورتین; Neurotrophic factors; Neurturin; AAV-NRTN; Parkinson's disease; Gene transfer; Axonopathy; Substantia nigra; Neuronal survival; Axon transport deficiencies; Animal model; 6-hydroxydopamine; Translational medicine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease

Keywords: نورورتین; Parkinson's disease; Translational research; Neurodegenerative diseases; Neurotrophic factors; Neurturin; CERE-120; Therapeutic development; Clinical 'proof-of-concept'; Gene transfer; Gene therapy; Viral vectors; Protein delivery;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

GDNF family ligand dependent STAT3 activation is mediated by specific alternatively spliced isoforms of GFRα2 and RET

Keywords: نورورتین; GDNF; glial cell line-derived neurotrophic factor; GFL; GDNF family ligand; NRTN; Neurturin; GFRα; GDNF family receptor alpha; RET; RE arranged during Transformation; STAT3; Signal Transducer and Activator of Transcription 3; NCAM; neural cell adhesion m

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2013 سفارش ترجمه

Recovery of behavioral symptoms in hemi-parkinsonian rhesus monkeys through combined gene and stem cell therapy

Keywords: نورورتین; differentiation; LMX1A; Neurturin; neuron; Parkinson disease; Rhesus adipose stem cells (rASCs); TH

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

The delivery of tyrosine hydroxylase accelerates the neurorestoration of Macaca Rhesus model of Parkinson's disease provided by Neurturin

Keywords: نورورتین; Parkinson's disease; Bicistronic; Neurturin; Tyrosine hydroxylase; Rhesus Macaque;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Translating the therapeutic potential of neurotrophic factors to clinical ‘proof of concept’: A personal saga achieving a career-long quest

Keywords: نورورتین; Translational research; Neurotrophic factor; Gene transfer; Gene therapy; Parkinson's disease; Neurturin; AAV; CERE-120; Therapeutic development; Proof of concept

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2012 سفارش ترجمه

Neurotrophic factors for the treatment of Parkinson's disease

Keywords: نورورتین; Glial cell line-derived neurotrophic factor; Growth/differentiation factor 5; Neurturin; Mesencephalic astrocyte-derived neurotrophic factor; Cerebral dopaminergic neurotrophic factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: Support for nigral targeting in Parkinson's disease

Keywords: نورورتین; Neurotrophic factors; Neurturin; Parkinson's disease; Translational research; Gene therapy; Gene transfer; Substantia nigra; Axonal transport; Between-species scaling; Substantia nigra volume;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Differential expression of RET receptor isoforms in the olfactory system

Keywords: نورورتین; RET isoforms; olfactory system; immunohistochemistry; olfactory ensheathing cells; olfactory receptor neurons; dopaminergic neurons; BDNF; brain derived neurotrophic factor; CNS; central nervous system; EPL; external plexiform layer; GAP-43; growth associ

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Neurturin protects against 6-hydroxydopamine-induced reductions in evoked dopamine overflow in rat striatum

Keywords: نورورتین; Neurturin; Striatum; Substantia Nigra; Dopamine; GDNF; 6-OHDA; Microdialysis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Parkinson's disease and growth factors - are they the answer?

Keywords: نورورتین; Parkinson's disease; Neurotrophic factors; GDNF; Neurturin; Trials;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Are growth factors the answer?

Keywords: نورورتین; Parkinson's disease; Gene therapy; Trophic factors; GDNF; Neurturin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease

Keywords: نورورتین; Huntington's disease; N171-82Q; Neurturin; CERE-120; Gene therapy; Transgenic mouse model; AAV2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Neural invasion in pancreatic cancer: A mutual tropism between neurons and cancer cells

Keywords: نورورتین; Neural invasion; Pancreatic cancer; In-vitro migration; Myenteric plexus; Dorsal root ganglia; NGF; GDNF; Artemin; Persephin; Neurturin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Current status of gene therapy trials for Parkinson's disease

Keywords: نورورتین; Parkinson's disease; Gene therapy; Clinical trials; Viral vectors; CERE-120; Neurturin; GDNF; AAV2-hAADC; AAV-GAD; Striatum; Subthalamic nucleus; Convection-enhanced delivery;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Treatment of Parkinson's Disease with Trophic Factors

Keywords: نورورتین; Parkinson's disease; trophic factors; clinical trials; glial-derived neurotrophic factors; neurturin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Emerging restorative treatments for Parkinson's disease

Keywords: نورورتین; Ad; adenovirus; AAV; adeno-associated virus; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; bFGF; basic fibroblast growth factor; CD45; cluster of differentiation 45; CNTF; ciliary neurotrophic factor; CSF; cerebrospinal fluid; DAT;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2008 سفارش ترجمه

Differential expression of glial cell line-derived neurotrophic factor family receptor alpha-2 isoforms in rat urinary bladder and intestine

Keywords: نورورتین; Neurturin; GDNF; Autonomic nervous system; Smooth muscle; RNA; Gene expression; Sprague-Dawley rat;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Neurotrophic factors for the treatment of Parkinson's disease

Keywords: نورورتین; Glial cell line-derived neurotrophic factor; GDNF; Neurturin; NTN; Brain-derived neurotrophic factor; BDNF; Bone morphogenetic protein 7; BMP7; Parkinson's disease; Neurotrophic factor; Neurodegenerative disease

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRα2

Keywords: نورورتین; Activated caspase-3; GDNF; Intrapancreatic neurons; Neurturin; Parasympathetic nervous system; Programmed cell death; Submandibular ganglion; TUNEL

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Issues regarding gene therapy products for Parkinson's disease: The development of CERE-120 (AAV-NTN) as one reference point

Keywords: نورورتین; Neurotrophic factors; Disease progression; Neurturin; Neuronal restoration; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: Long-term efficacy and tolerability of CERE-120 for Parkinson’s disease

Keywords: نورورتین; Parkinson’s disease; Neurturin; Glial cell line-derived neurotrophic factor; Gene delivery; Adeno-associated virus; 6-OHDA lesion; Neurotrophic therapy safety; Toxicity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease

Keywords: نورورتین; Huntington’s disease; Neurturin; Gene therapy; 3-Nitropropionic acid; Adenoassociated viral vector

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson’s disease

Keywords: نورورتین; Neurturin; Bone marrow stromal cell; Parkinson’s disease; Gene therapy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease

Keywords: نورورتین; Neural stem cell; Neurturin; Parkinson's disease; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Neurturin-GFRα2 signaling controls liver bud migration along the ductus venosus in the chick embryo

Keywords: نورورتین; Liver development; GDNF; Neurturin; Migration; Chick; Organogenesis; Endoderm; Chemoattractant; Ductus venosus; Endothelial cell

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys

Keywords: نورورتین; Aging; Dopamine; GDNF; Neurturin; Parkinson's disease; RET; Substantia nigra; Trophic factors

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Age-related alteration of neurturin receptor GFRa2 and nNOS in pelvic ganglia

Keywords: نورورتین; Aging; Castration; Glial cell line derived neurotrophic factor family receptor alpha-2 (GFRa2); Neuronal nitric oxide (nNOS); Cavernous nerve; Neurturin; Major pelvic ganglia (MPG); Erectile dysfunction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Expression of Nerve Growth Factor and Neurturin, and Their Receptors in Mouse Taste Buds

Keywords: نورورتین; neurotrophic factor; nerve growth factor; neurturin; TrkA; GFRa2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct

Keywords: نورورتین; Neurturin; Signal peptide; Pro-peptide processing; 6-hydroxydopamine lesion; Lentiviral delivery; Gene therapy; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Intrathecal injection of GDNF and BDNF induces immediate early gene expression in rat spinal dorsal horn

Keywords: نورورتین; Brain-derived neurotrophic factor; c-Fos; c-Jun; GDNF family receptor α1; Glial cell line-derived neurotrophic factor; Krox-24; Pain; Neurturin; RET; Tyrosine kinase B;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells

Keywords: نورورتین; ES cells; embryonic stem cells; ESGM; ES cell growth media; ESIM; ES cell induction media; MEM; Modified Eagle's media; LIF; leukemia inhibitory factor; PBS; phosphate buffered saline; NMDA; N-methyl-d-aspartate; NeuN+; NeuN immunopositive; GFL; GDNF fami

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Ret, GFRalpha-1, GFRalpha-2 and GFRalpha-3 receptors in the human hippocampus and fascia dentata

Keywords: نورورتین; CA; Cornus Ammonis; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GDNF; glial cell line-derived neurotrophic factor; GFAP; glial fibrillary acidic protein; GFRalpha; GDNF family receptor alpha; NTN; neurturin; ART; artemin; PSP; persephin; mw; molecula

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه