Keywords: واحدهای شیمیایی جدید; A549; lung cancer cells; 7-ACA; 7-aminocephalosporanic acid; 7-ADCA; 7-aminodesacetoksycephalosporanic acid; 6-APA; 6-aminopenicillanic acid; Asn; asparagine; Asp; aspartic acid; 4B16; murine melanoma cells; BE7404; liver cancer cells; BJAB; Burkitt's lym
مقالات ISI واحدهای شیمیایی جدید (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: واحدهای شیمیایی جدید; ADME; absorption distribution metabolism elimination; ASEs; aerosols solvent extractions; AUC; area under curve; BBB; blood-brain barrier; BCS; Biopharmaceutical Classification System; BDP; beclomethasone dipropionate; CFC; critical flocculation concent
Keywords: واحدهای شیمیایی جدید; Alzheimer's disease; MAO-B inhibitors; AChE inhibitors; New chemical entities; Chromone; Multi-target-directed ligands;
Keywords: واحدهای شیمیایی جدید; ADMET; adsorption distribution metabolism excretion and toxicity; CtD; complexity-to-diversity; DCC; N,Nâ²-dicyclohexylcarbodiimide; DCE; 1,2-dichloroethane; DIPEA; N,Nâ²-diisopropylethylamine; DMAP; 4-dimethylaminopyridine; DMF; N,Nâ²-dimethylformamid
Keywords: واحدهای شیمیایی جدید; Nanosuspension; Safety; Nanotoxicology; Sterilization; Drug delivery; NCEs; new chemical entities; MTD; maximum tolerated doses; IV; intravenous; MPS; mononuclear phagocyte system; EPR; enhanced permeability and retention; HPMC; hydroxy propyl methyl cell
Keywords: واحدهای شیمیایی جدید; log D; distribution coefficient; log P; partition coefficient; NCEs; new chemical entities; PBS; phosphate buffer saline; SGF; Simulated gastric fluid; SIF; Simulated intestinal fluid; RP-HPLC; reverse-phase high-performance liquid chromatography; tR; ret
Keywords: واحدهای شیمیایی جدید; Tuberculosis; Mycobacterium; New chemical entities; Phenotypic screening; Drug discovery;
Keywords: واحدهای شیمیایی جدید; 3Rs; replacement, refinement and reduction of animals in research; ACSA; Agricultural Chemicals Safety Assessment; ADA; anti-drug antibody; CNS; central nervous system; DBS; dried blood spot; DART; developmental and reproductive toxicity; DRF; dose range
Keywords: واحدهای شیمیایی جدید; Synthesis; New drug molecules; New chemical entities; Medicine; Therapeutic agents;
In vivo efficacy and pharmacokinetics of bi-aryl oxazolidinone RBx 11760 loaded polylactic acid-polyethylene glycol nanoparticles in mouse hematogenous bronchopneumonia and rat groin abscess caused by Staphylococcus aureus
Keywords: واحدهای شیمیایی جدید; Nanoparticles; PLA-PEG; Oxazolidinone; Staphylococcus aureus; Antibacterial; Nanomedicine; ATCC; American type culture collection; ATR-FTIR; attenuated total reflectance-Fourier transforms infrared spectroscopy; ACN; acetonitrile; ADME; absorption, dist
Development of solid SEDDS, VI: Effect of precoating of Neusilin® US2 with PVP on drug release from adsorbed self-emulsifying lipid-based formulations
Keywords: واحدهای شیمیایی جدید; SEDDS; Solid dosage forms; Silicates; Lipid based formulations; PVP; Pore size distribution; NCE's; new chemical entities; GI; gastro-intestinal; SEDDS; self-emulsifying drug delivery systems; SMEDDS; self-microemulsifying drug delivery systems;
Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats
Keywords: واحدهای شیمیایی جدید; drug interactions; in vitro/in vivo correlations; pharmacokinetics; protein binding; transporters; CYP enzymes; hepatocytes; organic anion-transporting polypeptide transporters; multidrug resistance transporters; solute transporters; ABT; 1-aminobenzotr
Oral toxicity of Miglyol 812® in the Göttingen® minipig
Keywords: واحدهای شیمیایی جدید; Miglyol 812®; Vehicle; Minipig; Medium-chain triglycerides; Oral; Toxicity; CMC; carboxymethylcellulose; NCE; new chemical entities;
Mucoadhesive oral films: The potential for unmet needs
Keywords: واحدهای شیمیایی جدید; APR; applied pharma research; BDSI®; BioDelivery Sciences International; BEMA®; BioErodible MucoAdhesive; CMC; carboxymethylcellulose; DDS; drug delivery systems; FDA; Food and Drug Administration; GI; gastrointestinal; HEC; hydroxyethyl cellulose; HPC;
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol
Keywords: واحدهای شیمیایی جدید; Liver X receptor agonists; Molecular modeling; New chemical entities; SAR; Gene regulation;
Ensemble docking and molecular dynamics identify knoevenagel curcumin derivatives with potent anti-EGFR activity
Keywords: واحدهای شیمیایی جدید; EGFR; epidermal growth factor receptor; TK; tyrosine kinases; NSCLC; non-small-cell lung carcinoma; NCEs; new chemical entities; MD; molecular dynamics; RMSD; root mean square deviation; EGFR; Tyrosine kinase; Curcumin; Ensemble docking; Molecular dynamic
Quantified tracking and monitoring of diazepam treated socially housed cynomolgus monkeys
Keywords: واحدهای شیمیایی جدید; Quantitative; Behaviour; Cynomolgus monkey; Locomotor activity; Group-housed nonhuman primates; Video-tracking; Long-tailed macaque; Automation of patterns of moving; COG; centre of gravity; FOB; functional observation battery; NCEs; new chemical entities
Synthetic approaches to the 2010 new drugs
Keywords: واحدهای شیمیایی جدید; Synthesis; New drug molecules; New chemical entities; Medicine; Therapeutic agents
Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Keywords: واحدهای شیمیایی جدید; Formyl peptide; Endogenous anti-inflammation; Annexin A1; New chemical entities; Novel therapeutics; Neutrophil migrationAc2–26, Peptide Ac2–26 of Annexin A1; AnxA1, Annexin A1; βA42, Beta-amyloid 1–42; C43, Compound 43; COX, Cyclo-oxygenase; ATL, Aspirin
A simple method for differentiation of monoisotopic drug metabolites with hydrogen-deuterium exchange liquid chromatography/electrospray mass spectrometry
Keywords: واحدهای شیمیایی جدید; Time-of-flight; New chemical entities; Biotransformation; Hydrogen-deuterium exchange; Post-column infusion;
Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo
Keywords: واحدهای شیمیایی جدید; AhR; aryl hydrocarbon receptor; CAR; constitutive androstane receptor; CYP; cytochrome P450; HPBCD; hydroxypropyl-β-cyclodextrin; MGB; minor groove binding; NCEs; new chemical entities; PAHs; polycyclic aromatic hydrocarbons; PB; phenobarbital; PCN; preg
Synthetic approaches to the 2012 new drugs
Keywords: واحدهای شیمیایی جدید; 1,2-DAP; 1,2-diaminopropane; 1,2-DCE; 1,2-dichloroethane; Ac; acetyl; aq; aqueous; B2(pin)2; bis(pinacolato)diboron; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthyl; BOP; benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophospate; CDI; N