Keywords: BMD; bone mineral density; BV/TV; bone volume fraction; BS; bone surface; BFR/BS; bone formation rate/bone surface; CFU-F; CFU-fibroblast; CFU-Ob; CFU-osteoblast; Car2; carbonic anhydrase II; CTSK; cathepsin K; DFO; deferoxamine mesylate; FPN1; ferroporti
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Keywords: AR; adrenergic receptor; BMAL1; brain and muscle arnt-like 1; BMP; bone morphogenetic protein; CCG; clock-controlled genes; CLOCK; circadian locomotor output cycles kaput; CRY; cryptochromes; E4BP4; E4 promoter-binding protein 4; FGF; fibroblast growth fa
Keywords: BMD; bone mineral density; BMSC; Bone marrow stromal cell; Col1a1; collagen type 1 alpha-1; CTSK; cathepsin K; CTx; cross-linked type I collagen; HDL; high density lipoprotein; HFD; high-fat diet; LDL; low density lipoprotein; LDLRâ/â; Low-density lip
Keywords: MNCs; multinucleated cells; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; M-CSF; macrophage colony stimulating factor; OPG; osteoprotegerin; c-fms; colony-stimulating factor-1 receptor; ERK; extracellul
Keywords: Tβ4; Expression; Differentiation; Periodontium; Periodontal ligament cells; NFATc1;
Keywords: AA; arachidonic acid; aP2 (or FABP4); adipocyte protein 2; BMD; bone mass density; BMP-2; bone morphogenic protein-2; CE; cholesterol esters; CHL; cholesterol; cAMP; cyclic 3,5-adenosine monophosphate; CLA; conjugated isomers of linoleic acid; COX; cycloo
Keywords: Osteoclast; Oleanolic acid acetate; PLCγ2; Calcium oscillation; NFATc1;
Keywords: LPS; lipopolysaccharide; TLR4; toll-like receptor-4; RANKL; receptor activator of nuclear factor κB ligand; RANK; receptor activator of nuclear factor κB; FBGC; foreign body giant cell; MEMκ; minimum essential medium alpha medium; PBS; phosphate-buffer
Keywords: g; gravitational acceleration; RANK; receptor activator of nuclear factor kappa-B; RANKL; RANK ligand; OPG; osteoprotegerin; Dlx5; distal-less homeobox protein 5; ALP; alkaline phosphatase; NFATC1; nuclear factor of activated T cells, cytoplasmic 1; DCSTA
Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation
Keywords: Methyl-3,5-di-O-caffeoyl-epi-quinate; Osteoclast; Differentiation; NFATc1;
Platycarya strobilacea leaf extract inhibits tumor necrosis factor-α production and bone loss induced by Porphyromonas gingivalis-derived lipopolysaccharide
Keywords: LPS; lipopolysaccharide; TNF-α; tumor necrosis factor (TNF)-α; RANKL; receptor activator of nuclear factor-κB ligand; ALP; alkaline phosphatase; M-CSF; macrophage-colony stimulating factor; NFATc1; nuclear factor of activated T cell c1; DC-STAMP; dendr
Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation
Keywords: Macrophage; Osteoclast; RANK; RANKL; NFATc1; Necrostatin-7; RANK; receptor activator of nuclear factor-kappa B; RANKL; RANK ligand; M-CSF; macrophage colony-stimulating factor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated ki
A flavonoids compound inhibits osteoclast differentiation by attenuating RANKL induced NFATc-1/c-Fos induction
Keywords: Pectolinarigenin; NFATc1;c-Fos; MAPKs; Signaling pathway; BMMs;
Osteon Myospalacem Baileyi attenuates osteoclast differentiation through RANKL induced NFAT pathways
Keywords: Osteon Myospalacem Baileyi; RANKL; Osteoclast differentiation; ERK; NFATc1;
Transcriptomic hallmarks of bone remodelling revealed by RNA-Seq profiling in blood of Arabian horses during racing training regime
Keywords: ACAP2; Arf-GAP with coiled-coil; ACLY; ATP citrate lyase; ADCY9; adenylate cyclase 9; AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; ARFGEF2; ADP ribosylation factor guanine nucleotide exchange factor 2; ARHGEF6; Rho guanine nucleotide excha
Tea polysaccharide inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells and ameliorates ovariectomy-induced osteoporosis in rats
Keywords: BMD; bone mineral density; RANKL; receptor activator nuclear factor-kappa B ligand; M-CSF; macrophage colony-stimulating factor; TPS; tea polysaccharide; OVX; ovariectomized; IL-1β; interleukin-1β; IL-6; interleukin-6; ELISA; enzyme-linked immunosorbent
TRIM38 regulates NF-κB activation through TAB2 degradation in osteoclast and osteoblast differentiation
Keywords: TRIM38; tripartite motif 38; BMM; bone marrow-derived macrophage-like cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor kappa B ligand; M-CSF; macrophage colony sti
Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated osteoclastogenesis
Keywords: IL-21/IL-21R; AA-FLS; PI3K/Akt; mTOR; Nfatc1; Osteoclastogenesis;
Tatarinan N inhibits osteoclast differentiation through attenuating NF-κB, MAPKs and Ca2+-dependent signaling
Keywords: Tatarinan N; Osteoclasts; NFATc1; c-Fos; MAPKs; NF-κB;
8-Nitro-cGMP is a promoter of osteoclast differentiation induced by RANKL
Keywords: Osteoclasts; 8-Nitro-cGMP; Nitric oxide; Reactive oxygen species; RANK; receptor activator of nuclear factor κ-B; RANKL; receptor activator of nuclear factor κ-B ligand; NFATc1; nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 1;
Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation
Keywords: Cathepsin K; Collagen type I; LAIR-1; Leukocyte receptor complex; NFATc1; Osteoclast;
BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway
Keywords: BCAP; B-cell adaptor for PI3K; PI3K; phosphatidylinositol 3-Kinase; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear
BCL3 regulates RANKL-induced osteoclastogenesis by interacting with TRAF6 in bone marrow-derived macrophages
Keywords: TRAF6; tumor necrosis factor receptor-associated factor 6; BCL3; B-cell chronic lymphatic leukemia protein 3; TAK1; transforming growth factor β-activated kinase 1; RANKL; Receptor activator of nuclear factor-κB ligand; NFATC1; nuclear factor of activat
Anti-osteoclastic effect of caffeic acid phenethyl ester in murine macrophages depends upon the suppression of superoxide anion production through the prevention of an active-Nox1 complex formation
Keywords: CAPE; caffeic acid phenethyl ester; RANKL; receptor activator of nuclear factor-κB ligand; TRAP; tartrate-resistant acid phosphatase; ROS; reactive oxygen species; Nox1; NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 1; NF-κB; nuclear facto
RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales
Keywords: RANKL; receptor activator of NF-κB ligand; RANK; receptor activator of nuclear factor κB; TRAP; tartrate-resistant acid phosphatase; NFATC1; Nuclear factor of activated T cells C1; CTSK; cathepsin K; OC-Stamp; osteoclast stimulatory transmembrane protei
Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review
Keywords: AD; Alzheimer's disease; AcOEt; Ethyl acetate; AOE; Ethanolic extract of the fruit of A. oxyphylla; AOF; Alpinia oxyphylla fruit; BBB; Blood-brain barrier; CAT; Catalase; CCl4; Carbon tetrachloride; CKD; Chronic kidney disease; EA portion; Ethyl acetate-s
The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review
Keywords: AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography
Inorganic phosphate-induced impairment of osteoclast cell-cell fusion by the inhibition of AP-1-mediated DC-STAMP expression
Keywords: Cell-cell fusion; c-Fos; DC-STAMP; Inorganic phosphate; NFATc1; Osteoclastogenesis;
25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p
Keywords: 25-hydroxycholesterol; miR-139-5p; NFATc1; Sp1; Osteoclast; RANKL;
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca2+-calcineurin-NFATc1 signaling pathway
Keywords: PEMF; Osteoclastic differentiation; Ca2+ oscillation; Calcineurin; NFATc1;
MicroRNA-34a targets regulator of calcineurin 1 to modulate endothelial inflammation after fetal cardiac bypass in goat placenta
Keywords: MicroRNAs; Placental insufficiency; Endothelial cells; Inflammation; Fetus; Cardiopulmonary bypass; miRNA; microRNA; miR-34a; miRNA-34a; mRNA; messenger RNA; 3'-untranslated regions (UTRs); untranslated region; RCAN1; regulator of calcineurin 1; NFATC1;
Alpinumisoflavone inhibits osteoclast differentiation and exerts anti-osteoporotic effect in ovariectomized mice
Keywords: Alpinumisoflavone; Ovariectomy-induced bone loss; c-Fos; NFATc1;
Neuromedin B and its receptor silencing suppresses osteoclast generation by modulating precursor proliferation via M-CSF/c-Fms/D-type cyclins
Keywords: BMM; bone marrow macrophage; M-CSF; macrophage colony-stimulating factor; NFATc1; nuclear factor of activated T cells c1; NMB; neuromedin B; NMBR; neuromedin B receptor; RANKL; receptor activator of NF-κB ligand; TRAP; tartrate-resistant acid phosphatase
Sciadopitysin suppresses RANKL-mediated osteoclastogenesis and prevents bone loss in LPS-treated mice
Keywords: Osteoclasts; Bone resorption; NFATc1; Bone loss; NF-κB; RANKL;
Daily chemical evodiamine from Chinese prickly ash attenuates osteoclast differentiation through RANKL induced NFAT pathways
Keywords: CTSK; cathepsin K; NFATc1; nuclear factor of activated T cells cytoplasmic 1; TRAP, Acp5; tartrate resistant acid phosphatase; DC-STAMP; dendrite cell-specific transmembrane protein; CTR; calcitonin receptor; OSCAR; osteoclast associated and immunoglobuli
Urtica thunbergiana prevents UVB-induced premature skin aging by regulating the transcription factor NFATc1: An in vitro and in vivo study
Keywords: Urtica thunbergiana; Skin; Anti-aging; UVB; NFATc1; Chlorogenic acid;
Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro
Keywords: Gastrodin; Osteoclasts; Differentiation; NFATc1; Osseointegration;
ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins
Keywords: ATF3; activating transcription factor; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; Osteoclast
Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways
Keywords: Salicortin; Osteoclastogenesis; JNK; NF-κB/NFATc1; BMM; bone marrow macrophage; JNK; c-Jun N-terminal kinase; M-CSF; macrophage colony-stimulating factor; NFATc1; nuclear factor of activated T cells c1; RANKL; receptor activator of nuclear factor-κB lig
Identification of Spongionella compounds as cyclosporine A mimics
Keywords: Calcineurin; NFATc1; T lymphocyte; Spongionella; Cyclophilin A; IL-2;
Cytosolic malate dehydrogenase regulates RANKL-mediated osteoclastogenesis via AMPK/c-Fos/NFATc1 signaling
Keywords: Osteoclast; MDH1; RANKL; AMPK; c-Fos; NFATc1;
Tatarinan O, a lignin-like compound from the roots of Acorus tatarinowii Schott inhibits osteoclast differentiation through suppressing the expression of c-Fos and NFATc1
Keywords: Tatarinan O; Osteoclast; Bone resorption; NFATc1; c-Fos; RANKL
Herbacetin inhibits RANKL-mediated osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo
Keywords: Herbacetin; Osteoclast; RANKL; NFATc1; Bone loss
Effects of gallotannin on osteoclastogenesis and the p38 MAP kinase pathway
Keywords: Osteoclast; Gallotannin; Tannin; p38 MAP kinase; NFATc1;
Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation via NFATc1 activation
Keywords: BMMs; bone marrow macrophages; CCR9; CCchemokine receptor 9; LPS; lipopolysaccharide; NFATc1; nuclear factor of activated T cells cytoplasmic 1; NF-κB; nuclear factor κB; P. gingivalis; Porphyromonas gingivalis; RANKL; receptor activator of nuclear fact
E-cadherin is important for cell differentiation during osteoclastogenesis
Keywords: DC-STAMP; dendritic cell-specific transmembrane protein; bAb; blocking antibody; pre-OC; pre-osteoclast; ICAM-2; intercellular adhesion molecule-2; Mac-1; macrophage antigen 1; ASCT2; alanine-serine-cysteine-preferring neutral amino acid transporter 2
Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption
Keywords: Salicylanilide; 3-Phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione; Osteoclast; NFATc1; IDBOTYTXAFSKNM-UHFFFAOYSA-N; IMTYSNSPCDNDMX-UHFFFAOYSA-N; YUANXIAYECFAMD-UHFFFAOYSA-N; HHGYSGPMGVTOKX-UHFFFAOYSA-N; LEWZGUAYGDKHIZ-UHFFFAOYSA-N; LZHBVNDEKDYBCT-UHFFFAOYSA-
Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice
Keywords: Connexin; NFATc1; Foxc2; Valve development; Chronic venous disease; Lymphedema;
Follistatin-like 1 promotes osteoclast formation via RANKL-mediated NF-κB activation and M-CSF-induced precursor proliferation
Keywords: BMM; bone marrow-derived macrophage; FSTL1; follistatin-like 1; M-CSF; macrophage colony-stimulating factor; NFATc1; nuclear factor of activated T cells c1; RANKL; receptor activator of NF-κB ligand; TRAP; tartrate-resistant acid phosphatase.; FSTL1; Ost
Notch2 signaling promotes osteoclast resorption via activation of PYK2
Keywords: DBZ; dibenzazepine; NFATc1; nuclear factor of activated T cells, cytoplasmic 1; PYK2; proline-rich tyrosine kinase 2; NICD2; Notch intracellular domain 2; IL-1; interleukin 1; Dibenzazepine (PubChem CID: 11454028); Osteoclast; Notch2; Dibenzazepine; PYK2;