NFATc1 regulates the transcription of DNA damage-induced apoptosis suppressor
Keywords: DDIAS; NFATc1; ChIP; Lung cancer; Pancreatic cancer
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Insulin enhances RANKL-induced osteoclastogenesis via ERK1/2 activation and induction of NFATc1 and Atp6v0d2
Keywords: Osteoclast differentiation; Insulin; ERK1/2; NFATc1; Atp6v0d2;
Involvement of PU.1 in NFATc1 promoter function in osteoclast development
Keywords: NFATc1; Osteoclasts; Promoter; PU.1; Transcription factorBM, bone marrow; ChIP, chromatin immunoprecipitation; DC, dendritic cells; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; TRAP, tartrate resistant acid phosphatase
Effect of BioAggregate on Receptor Activator of Nuclear Factor-Kappa B Ligand–induced Osteoclastogenesis from Murine Macrophage Cell Line In Vitro
Keywords: BioAggregate; NFATc1; osteoclastogenesis; receptor activator for nuclear factor kappaB; root repair
Esculetin attenuates receptor activator of nuclear factor kappa-B ligand-mediated osteoclast differentiation through c-Fos/nuclear factor of activated T-cells c1 signaling pathway
Keywords: Esculetin; Osteoclast; c-Fos; NFATc1; F-actin ring;
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints
Keywords: Nfatc1; ALK2; Acvr1; BMP receptor; Heterotopic ossification; Fibrodysplasia ossificans progressive; FOP; Cartilage; Bone; Endochondral ossification;
NFATc1 activity regulates the expression of myocilin induced by dexamethasone
Keywords: Glucocorticoids; Glaucoma; Trabecular meshwork; Calcineurin; NFATc1; MyocilinCsA, cyclosporin A; DEX, dexamethasone; EtOH, ethanol; HTM, human trabecular meshwork; IOP, intraocular pressure; MYOC, myocilin; NFAT, Nuclear factor of activated T-cells; POAG,
Osteogenic differentiation of human MSCs: Specific occupancy of the mitochondrial DNA by NFATc1 transcription factor
Keywords: Osteogenic differentiation; Mesenchymal stem cells; Mitochondria; NFATc1; Chromatin immunoprecipitation assay;
Zoledronate inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclast differentiation via suppression of expression of nuclear factor of activated T-cell c1 and carbonic anhydrase 2
Keywords: Bisphosphonate; Zoledronate; DNA microarray; RANKL; NFATc1; CAII;
Mollugin from Rubea cordifolia suppresses receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis and bone resorbing activity in vitro and prevents lipopolysaccharide-induced bone loss in vivo
Keywords: Mollugin; Rubea cordifolia; Osteoclastogenesis; Bone resorption; NFATc1;
In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz
Keywords: Osteoclasts; NFATc1; c-Fos; JunB; Salubrinal; Guanabenz;
Syndecan-4 ectodomain evokes mobilization of podocyte TRPC6 channels and their associated pathways: An essential role for integrin signaling
Keywords: ADAM17; A disintegrin and metalloproteinase 17; Ang II; angiotensin II; CGT; cilengitide; CsA; cyclosporine A; DAG; diacylglycerol; FSGS; focal and segmental glomerulosclerosis; GBM; glomerular basement membrane; NFATc1; nuclear factor of activated T-cell
Role of protein kinase CK2 in the dynamic interaction of platelets, leukocytes and endothelial cells during thrombus formation
Keywords: ADP; adenosin diphosphate; DAPI; 4â²,6-diamidine-2â²-phenylindole dihydrochloride; DMSO; dimethyl sulfoxide; DRB; 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole; ELISA; enzyme-linked immunosorbent assay; ER; endoplasmatic reticulum; FITC; fluorescein is
Scoparone attenuates RANKL-induced osteoclastic differentiation through controlling reactive oxygen species production and scavenging
Keywords: TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; ROS; reactive oxygen species; Nox1; NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 1; SOD 1; superoxide dismutase 1; CAT; catalase; NFATc1; nuc
n-3 polyunsaturated fatty acids stimulate osteoclastogenesis through PPARγ-mediated enhancement of c-Fos expression, and suppress osteoclastogenesis through PPARγ-dependent inhibition of NFkB activation
Keywords: AA; arachidonic acid; aP2; adipocyte fatty acid binding protein; BMCs; bone marrow cells; BMMs; bone marrow-derived macrophage/monocyte precursor cells; COX2; cyclooxygenase 2; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; LA; linoleic acid; M-CS
Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling
Keywords: Ursolic acid; Osteoclastogenesis; NF-κB; Titanium particle; Osteolysis; AP-1; activator protein-1; BV/TV; bone volume/tissue volume; BMD; bone mineral density; BMC; bone mineral content; BMMs; bone marrow monocytes; CK; cathepsin K; CT; computed tomograp
Synergy between IL-6 and soluble IL-6 receptor enhances bone morphogenetic protein-2/absorbable collagen sponge-induced bone regeneration via regulation of BMPRIA distribution and degradation
Keywords: BMP-2; IL-6; sIL-6R; BMPRIA; Bone regeneration; Cell surface translocation; BMP-2; bone morphogenetic protein-2; BMPRIA; bone morphogenetic protein receptor IA; BMPRIB; bone morphogenetic protein receptor IB; BMPRII; bone morphogenetic protein receptor II
Miconazole inhibits receptor activator of nuclear factor-κB ligand-mediated osteoclast formation and function
Keywords: Miconazole nitrate (PubChem CID: 68553).Miconazole; Osteoclast; RANKL; NFATc1; Bone loss
Inhibitory activity on RANKL-mediated osteoclastogenesis of Glossogyne tenuifolia extract
Keywords: EA; ethyl acetate; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FBS; fetal bovine serum; GT; Glossogyne tenuifolia; GTE; Glossogyne tenuifolia ethanolic extract; IGEPAL; tert-octylphenoxy poly(oxyethylene)ethanol; JNK; c-
A comparative study of the bone metabolic response to dried plum supplementation and PTH treatment in adult, osteopenic ovariectomized rat
Keywords: AIN; American Institute of Nutrition; Alp; alkaline phosphatase; BAP; bone-specific alkaline phosphatase; BFR; bone formation rate; BMD; bone mineral density; BMP; bone morphogenetic protein; BV/TV; bone volume per total volume; Conn Density; connectivity
A novel microRNA regulates osteoclast differentiation via targeting protein inhibitor of activated STAT3 (PIAS3)
Keywords: miRNAs; microRNAs; PIAS3; protein inhibitor of activated STAT3; M-CSF; macrophage colony stimulating factor; RANKL; receptor activator of nuclear factor-κB ligand; RANK; receptor activator of NF-κB; OPG; osteoprotegerin; MAPKs; mitogen-activated protein
The mechanism of anti-osteoporosis effects of 3-hydroxybutyrate and derivatives under simulated microgravity
Keywords: Osteoporosis; Microgravity; PHB; 3-Hydroxybutyrate acid; 3-Hydroxybutyrate methyl ester; NFATc1
Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis
Keywords: Wnt3a; Osteoclasts; RANKL; NFATc1; c-Fos;
Osterix/Sp7 regulates biomineralization of otoliths and bone in medaka (Oryzias latipes)
Keywords: Bmp; bone morphogenetic protein; Col; collagen; Dlx; distal-less gene; Elf; elongation factor; Eya; eyes absent gene; MO; morpholino oligonucleotide; Msx; muscle segment homeobox gene; NFATc1; nuclear factor of activated T cells; nlGFP; nuclear green fluo
The effect of metallic magnesium degradation products on osteoclast-induced osteolysis and attenuation of NF-κB and NFATc1 signaling
Keywords: Magnesium; Osteoclast; Osteolysis; NF-κB; NFATc1;
The effect of dose on rhBMP-2 signaling, delivered via collagen sponge, on osteoclast activation and in vivo bone resorption
Keywords: rhBMP-2; High-dose; Osteoclast activation; RANKL; NFATc1; Bone formation
The prevention of titanium-particle-induced osteolysis by OA-14 through the suppression of the p38 signaling pathway and inhibition of osteoclastogenesis
Keywords: Total joint arthroplasty; OA-14; Osteoclast; Osteolysis; MAP kinase; NFATc1;
EDF-1 downregulates the CaM/Cn/NFAT signaling pathway during adipogenesis
Keywords: Cn; calcineurin; CaM; calmodulin; CsA; cyclosporine A; Dex; dexamethasone; EDF-1; endothelial differentiation factor-1; Iono; ionomycin; NFAT; nuclear factor of activated T-cells; St; staurosporine; Differentiation; Adipogenesis; edf1; Calmodulin; Calcine
Recombinant human erythropoietin pretreatment alleviates renal glomerular injury induced by cardiopulmonary bypass by reducing transient receptor potential channel 6-nuclear factor of activated T-cells pathway activation
Keywords: 41.3; 41.1; ARI; acute renal injury; CPB; cardiopulmonary bypass; EMSA; electrophoretic mobility shift assay; IP; intraperitoneally; NFAT; nuclear factor of activated T cell; NFATc1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent
AG490 inhibits NFATc1 expression and STAT3 activation during RANKL induced osteoclastogenesis
Keywords: Osteoclastogenesis; AG490; RANKL; NFATc1; JAK2/STAT3;
MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31
Keywords: 3â²UTR; 3â² untranslated region; ALP; Alkaline phosphatase; AP-1; Activator protein 1; ATF4; Activating transcription factor 4; BGLAP; Bone gamma-carboxyglutamate (gla) protein; BMP; Bone morphogenetic protein; COL1A1; Collagen, type I, alpha 1; FBS; Fe
Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation
Keywords: OC; osteoclast; M-CSF; macrophage colony-stimulating factor; NF-κB; nuclear factor-κB; RANKL; receptor activator of NF-κB ligand; TNF; tumor necrosis factor; TRAF; TNF receptor-associated factor; MAPK; mitogen-activated protein kinase; JNK; c-Jun N-ter
Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-κB
Keywords: ApoE; Apolipoprotein E; BMMs; Bone marrow-derived macrophages; RANKL; Receptor activator of NF-κB ligand; M-CSF; Macrophage colony-stimulating factor; NFATc1; Nuclear factor of activated T cell c1; TRAP; Tartrate-resistant acid phosphatase; OSCAR; Osteoc
Aminocoumarins inhibit osteoclast differentiation and bone resorption via downregulation of nuclear factor of activated T cells c1
Keywords: Aminocoumarins; Osteoclast; RANKL; NFATc1; c-Fos; Bone lossBMM, bone marrow-derived macrophages; M-CSF, macrophage CSF; RANKL, receptor activator of NF-kB ligand; TRAP, tartrate-resistant acid phosphatase; μCT, microcomputer tomography
The effect of CD137-CD137 ligand interaction on the expression of NFATc1 in apolipoprotein E-deficient mice
Keywords: CD137; CD137L; NFATc1; Atherosclerosis;
Regulation of ITAM adaptor molecules and their receptors by inhibition of calcineurin-NFAT signalling during late stage osteoclast differentiation
Keywords: Osteoclast; ITAM; Calcineurin; NFATc1; FK506; VIVIT; β3 Integrin; Annexin VIII
Deltamethrin inhibits osteoclast differentiation via regulation of heme oxygenase-1 and NFATc1
Keywords: Abs; antibodies; OCLs; osteoclasts; RANK; receptor activator of nuclear factor kappa-B; RANKL; receptor activator of nuclear factor kappa-B ligand; BMMs; bone marrow-derived macrophages; TRAP; tartrate-resistant acid phosphatase; NFATc1; nuclear factor of
The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development
Keywords: Calcineurin; Nfatc1; Secondary heart field; Semilunar valve; Endocardial cushion
VapB as a regulator of osteoclastogenesis via modulation of PLCγ2-Ca2+-NFAT signaling
Keywords: Osteoclast; VapB; PLCγ2; NFATc1
A novel small molecule, NecroX-7, inhibits osteoclast differentiation by suppressing NF-κB activity and c-Fos expression
Keywords: Osteoclast; NecroX-7; NF-κB; c-Fos; NFATc1;
Ginsenoside Rh2 inhibits osteoclastogenesis through down-regulation of NF-κB, NFATc1 and c-Fos
Keywords: Ginsenoside Rh2; Osteoclast; NF-κB; NFATc1; Osteoporosis;
Molecular effects of gallium on osteoclastic differentiation of mouse and human monocytes
Keywords: Gallium; Osteoclast; CD11b+; NFATc1; NFκB; Calcium
Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish
Keywords: Zebrafish; Heart; Endocardium; Hedgehog; Fibronectin; NFATc1; Endoderm; Cyclopamine; Smoothened; Notochord;
High extracellular calcium-induced NFATc3 regulates the expression of receptor activator of NF-κB ligand in osteoblasts
Keywords: Cnb1; calcineurin regulatory subunit; ChIP; chromatin immunoprecipitation; NFATc1NUC; constitutively nuclear NFATc1; CsA; cyclosporin A; [Ca2+]o; extracellular calcium; MC4; MC3T3-E1 subclone 4; MCCs; mouse calvarial osteoblasts; Osteoblasts; NFATc1; NFAT
The small molecule harmine regulates NFATc1 and Id2 expression in osteoclast progenitor cells
Keywords: DYRK1A; Harmine; Id2; NFATc1; Osteoclast; Small molecule;
Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo
Keywords: Doxycycline; Osteoclast; RANK ligand; MMP-9; MAPKs; NFATc1
Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression
Keywords: RANKL; RIZ1; NFATc1; RAW 264.7; Osteoclastogenesis
NFATc1: Functions in osteoclasts
Keywords: NFATc1; Osteoclasts; RANKL; Ca2+; Autoamplification
Bone regulatory factors NFATc1 and Osterix in human calcific aortic valves
Keywords: Calcific; Aortic valves; NFATc1; Osterix
Gymnasterkoreayne F inhibits osteoclast formation by suppressing NFATc1 and DC-STAMP expression
Keywords: GK-F; Osteoclasts; NFATc1; DC-STAMP; β3 integrin