دانلود مقالات ISI درباره Nicd + ترجمه فارسی

ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice

Keywords: CBC; Intestinal Epithelium; Development; Differentiation; ADAM10; A disintegrin and metalloproteinase domain-containing protein 10; CBCs; crypt-based columnar cells; Dll; Delta-like ligand; EGFP; enhanced green fluorescent protein; IP; intraperitoneally;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor protein; CTF; carboxyl-terminal fragment; FTH; ferritin heavy chain; FTL; ferritin light chain; HEK293Swe; HEK293 cells stably expressing human APP Swedish mutations; NICD; notch intracel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Hypoxia inhibits the differentiation of mesenchymal stem cells into osteoblasts by activation of Notch signaling

Keywords: MSCs; mesenchymal stem cells; SD; Male Sprague-Dawley; ARS; Alizarin red S; ALP; Alkaline phosphatase; NICD; Notch in intracellular domain; Mesenchymal stem cell; Osteoblast; Hypoxia; Notch signaling;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Basic NeuroscienceAn improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates

Keywords: GSI; γ-secretase inhibitor; GSM; γ-secretase modulator; NICD; Notch intracellular domain; β-Amyloid; Aβ; 2B; 7CHO-2B7; γ-Secretase; Notch; Aβ; Alzheimer's Disease; Modulator; NICD;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway

Keywords: CSLCs; cancer stem-like cells; GBM; glioblastoma multiforme; ATO; arsenic trioxide; GSI; γ-secretase inhibitors; Hes1; hairy enhancer of split 1; Hey1; Hes-related protein 1; APL; acute promyelocytic leukemia; GSLCs; glioblastoma stem like cells; NICD; N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Caveolin-1 regulates neural differentiation of rat bone mesenchymal stem cells into neurons by modulating Notch signaling

Keywords: Caveolin-1; MSCs; Differentiation; Notch-1; NICD; Hes5; Neuron

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of Tumor Angiogenesis and Tumor Growth by the DSL Domain of Human Delta-Like 1 Targeted to Vascular Endothelial Cells

Keywords: Dll1; Delta-like 1; ECs; endothelial cells; HUVECs; human umbilical vein endothelial cells; RGD; arginine-glycine-aspartate; NICD; intracellular domain of Notch receptors;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Notch ligand endocytosis: Mechanistic basis of signaling activity

Keywords: ADAM; a disintegrin and metalloprotease; AFM; atomic force microscopy; CSL; CBF1, Su(H), LAG-1; Dll; Delta-like; EDTA; ethylenediaminetetraacetic acid; GSI; γ-secretase inhibitor; HD; heterodimerization domain; LNRs; Lin12/Notch repeats; NECD; Notch extr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Protein kinase Cδ negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro

Keywords: ChIP; chromatin immunoprecipitation; DAPI; 4′,6-diamidino-2-phenylindole; DLL; delta-like; DTT; dithiothreitol; ER; estrogen receptor; HDAC; histone deacetylase; NICD; Notch1 intracellular domain; PKCδ; protein kinase Cδ; PKCδ K376R; kinase-dead domi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Notch Signaling Is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice

Keywords: Genetically Engineered Mouse Model; Notch Activation; Gene Expression Profiling; AFP; α-fetoprotein; GFP; green fluorescent protein; GSI; γ-secretase inhibitor; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; Igf2; insulin-like growth factor 2; I

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

hCLP46 regulates U937 cell proliferation via Notch signaling pathway

Keywords: hCLP46; human CAP10-like protein 46 kDa; Poglut; protein O-glucosyltransferase; Poglut1; protein O-glucosyltransferase1 (mammalian); CDKI; cyclin-dependent kinase inhibitor; CDKN1B (p27); cyclin-dependent kinase inhibitor 1B; RB; retinoblastoma; CSL; CBF

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of remyelination in multiple sclerosis

Keywords: Remyelination; Oligodendrocytes; Hyaluronan; Wnt; Notch1; Retinoid X receptor; 15d-PGJ(2); 15-deoxy-Δ12,14-prostaglandin J2; CNP; 2′,3′-cyclic nucleotide 3′-phosphodiesterase; CNS; central nervous system; cKO; conditional knockout; dpl; days post l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic trafficking of ligands and receptors

Keywords: Notch; Endocytosis; Signaling; Receptor; DSL ligands; EGF; epidermal growth factor; NRR; negative regulatory region (structural domain of Notch that shields S2 cleavage site in absence of ligand binding and activation); LNR; Lin12/Notch repeat; HD; hetero

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Notch: Architect, Landscaper, and Guardian of the Intestine

Keywords: Intestine; Stem Cells; Homeostasis; Notch; Colon Cancer; AES; Amino terminal Enhancer of Split; AMP; adult midgut progenitor; bHLH; basic helix-loop-helix; CBC; columnar base cell; Dll; Delta-like ligand; EB; enteroblast; EC; enterocyte; EE; enteroendocri

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Presenilin mouse and zebrafish models for dementia: Focus on neurogenesis

Keywords: AD; Alzheimer's disease; PSEN; presenilin; APP; amyloid precursor protein; Aβ; β-amyloid; FAD; familial forms of AD; SVZ; subventricular zone; SGZ; subgranular zone; DG; dentate gyrus; NSCs; neural stem cells; DCX; doublecortin; NPC; neural progenitor c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Dll1- and Dll4-Mediated Notch Signaling Are Required for Homeostasis of Intestinal Stem Cells

Keywords: GI Development; Knockout Mice; Intestinal Stem Cells; Gene Regulation; DBZ; dibenzazepine; Dll; Delta-like; Jag; Jagged; Klf4; Krüppel-like factor 4; NICD; Notch1 intracellular domain; qRT-PCR; quantitative reverse-transcription polymerase chain reaction

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2011 سفارش ترجمه

Notch signaling and Atoh1 expression during hair cell regeneration in the mouse utricle

Keywords: CSF; cerebrospinal fluid; GER; greater epithelial ridge; NICD; Notch intracellular domain; PBS; phosphate-buffered saline; PFA; paraformaldehyde; qRTPCR; quantitative real-time polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories

Keywords: AICD; NICD; Transcription; Nuclear signaling; Live cell imaging; Tip60; Fe65; Nuclear bodies; FISH

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

The Notch pathway mediates expansion of a progenitor pool and neuronal differentiation in adult neural progenitor cells after stroke

Keywords: Notch pathway; neural progenitor cell; proliferation; differentiation; stroke; rat; bFGF; basic fibroblast growth factor; BrdU; bromodeoxyuridine; CBF1; C-promoter binding factor 1; CNTF; ciliary neurotrophic factor; DAPI; 4′,6′-diamidino-2-phenylindo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury

Keywords: cerebral ischemia; γ-secretase; hippocampus; neurogenesis; regeneration; aCSF; artificial cerebrospinal fluid; APP; amyloid precursor protein; aSVZ; anterior subventricular zone; BrdU; bromodeoxyuridine; DCX; doublecortin; DLL4; delta-like protein 4; DMS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction

Keywords: Beta-catenin; Notch1; NICD; HES1; LEF1; Osteogenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Down-regulation of Notch-dependent transcription by Akt in vitro

Keywords: NICD, Notch intracellular domain; dnAkt, dominant negative Akt; HDAC, histone deacetylase; TSA, trichostatin A; SMRT, silencing mediator of retinoid and thyroid hormone receptors; GSK3β, glycogen synthase kinase 3βAkt; NICD; Notch; Transcription

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Olfactory ensheathing cells promote proliferation and inhibit neuronal differentiation of neural progenitor cells through activation of Notch signaling

Keywords: conditioned medium; spinal cord injury; DAPT; BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo2′-deoxy-uridine; DMSO; dimethyl sulfoxide; FGF2; fibroblast growth factor-2; GDNF; glial cell-derived neurotrophic factor; GFAP; glial fibrillary acidic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Intestinal Deletion of Pofut1 in the Mouse Inactivates Notch Signaling and Causes Enterocolitis

Keywords: BSA; bovine serum albumin; CVA; crypt-villus axis; GALT; gut-associated lymphoid tissue; GSI; γ-secretase inhibitor; HES; hairy and enhancer of split; HRP; horseradish peroxidase; NICD; Notch intracellular domain; MLN; mesenteric lymph nodes; PCR; polyme

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders

Keywords: ADAM; a disintegrin and metalloprotease; ACDL; acidic dileucine; ADDL; amyloid-β derived diffusible ligands; APP; amyloid precursor protein; Aph; anterior pharynx defective phenotype; APLP; APP-like protein; AICD; APP intracellular domain; AD; Alzheimer'

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Fe65 does not stabilize AICD during activation of transcription in a luciferase assay

Keywords: Aβ; β-amyloid peptide; APP; amyloid precursor protein; AICD; APP intracellular domain; sαAPP; soluble α-amyloid precursor protein; BACE; β-site APP-cleaving enzyme; CHO; Chinese hamster ovary; CTF; C-terminal fragment of APP; DAPT; N-[N-(3,5-difluoro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Matrix Metalloproteinase-9 Regulates MUC-2 Expression Through Its Effect on Goblet Cell Differentiation

Keywords: AB; Alcian Blue; CA; carbonic anhydrase; ECM; extracellular matrix; MMP; matrix metalloproteinases; NICD; Notch intracellular domain; PAS; periodic acid-Schiff stain; WT; wild type;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Presenilin endoproteolysis is an intramolecular cleavage

Keywords: Aβ; amyloid-β peptide; APP; β-amyloid precursor protein; CTF; C-terminal fragment; ELISA; enzyme-linked immunosorbent assay; FL; full-length; HEK; human embryonic kdney 293; IP; immunoprecipitation; MEF; mouse embryonic fibroblasts; NΔE; Notch ΔE; NC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis

Keywords: Arf6; ARF ribosylation factor 6; bHLH; basic helix-loop-helix; CSL; CBF1, Supressor of Hairless, Lag-1; DSL; Delta, Serrate, Lag-2; E(spl); Enhancer of Split; JNK; jun N-terminal kinase; MADS; MCM1, agamous, deficiens, serum response factor; MEF2; myocyte

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Inducible Nitric Oxide Synthase Up-Regulates Notch-1 in Mouse Cholangiocytes: Implications for Carcinogenesis

Keywords: BrdU; 5-bromo-2′-deoxyuridine; CCA; cholangiocarcinoma; COX-2; cyclooxygenase-2; DAPT; N-[N-(3,5-difluorophenacetyl-L-alanyl)-S-phenylglycine]-t-butyl ester; GSNO; S-nitroso-L-glutathione; Hes; hairy and enhancer of split; iNOS; inducible nitric oxide s

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه