Keywords: 5-Aza; 5-Aza-2-deoxycytidine; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; BIR; baculoviral inhibitor of apoptosis repeat; CAD; caspase-activated deoxyribonuclease; CDK; cyclin-dependent kinase; cIAP; cellular inhibitor of apoptosis; CL
مقالات ISI (ترجمه نشده)
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Keywords: AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;
Keywords: Ectodermal dysplasia with immune deficiency; NF-κB inhibitor α; canonical nuclear factor κB pathway; noncanonical nuclear factor κB pathway; lymphorganogenesis; hematopoietic stem cell transplantation; AD EDA-ID; Autosomal dominant anhidrotic ectoderm
Keywords: COPD; chronic obstructive pulmonary disease; DAMPs; damage-associated molecular patterns; DC; dendritic cells; IFN; interferon; IKK (IKB); inhibitor kappa B kinase; IL; interleukins; MHC; major histocompatibility complex; MyD88; myeloid differentiation pr
Keywords: Ginger; Multiple sclerosis; Experimental autoimmune encephalomyelitis; Therapeutic potentials; AP-1; Activator protein 1; APCs; Antigen-presenting cells; ASC; apoptosis speck-like protein containing CARD; BAFF; B cell-activating factor belonging to the TN
Keywords: Cytokines; Signal transduction; Drug development; Inflammation; Autoimmunity; Therapy; JAK; Janus Kinase; STAT; Signal transducer and activator of transcription; NF-kB; nuclear factor kappa-light-chain-enhancer of activated B cells; MAPK; Mitogen activate
Keywords: Gut-Kidney axis; Inflammation; Kidney injury; Short-chain fatty acids; AKI; acute kidney injury; βarrs; β-arrestins; cAMP; cyclic adenosine monophosphate; CKD; chronic kidney disease; CIN; contrast-induced nephropathy; ESRD; end-stage renal disease; E
Keywords: ADCC; antibody-dependent cell-mediated cytotoxicity; AP3; adaptor protein 3; CHS; Chediak-Higashi syndrome; CMV; cytomegalovirus; CNKD; classical natural killer cell deficiency; CrkL; chicken tumor virus number 10 regulator of kinase-like; CTL; cytotoxi
Keywords: AP-1; activator protein 1; APC; antigen-presenting cells; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; CBP; CREB binding protein; CsA; ciclosporin A; ERK; Extr
Keywords: Primary immune deficiency; microscopy; cell biology; cytoskeleton; host defense; AP3; Adaptor protein 3; Arp2/3; Actin-related proteins 2 and 3; CDC42; Cell division cycle 42; CGD; Chronic granulomatous disease; CHS; Chediak-Higashi syndrome; CTL; Cytotox
Keywords: BMI; body mass index; NIK; Neighborhood Impact on Kids Study; METs; metabolic equivalents; MVPA; moderate-to-vigorous physical activity; Childhood obesity; Screen time; Basketball; Parental support; Home environment; Physical activity equipment; Electroni
Keywords: CD 14; cluster determinant 14; TLR; toll like receptor; TNF; tumor necrotic factor; EGFR; epidermal growth factor receptor; ODE; ordinary differential equation; PCA; principal component analysis; NIK; NFκB-inducing kinase; MKK; mitogen kinase kinases; PI
Keywords: AA; arachidonic acid; ADF; actin depolymerizing factor; AIF; apoptosis-inducing factor; ASIC; acid-sensing ion channel; BBB; blood-brain barrier; BK; bradykinin; CAMKII; Ca2+/calmodulin (CaM)-dependent protein kinase II; CHP; calcineurin homologous prot
NF-κB pathways in the development and progression of colorectal cancer
Keywords: 5-FU; 5-fluorouracil; AMPK/mTOR; AMP-activated Protein Kinase/mammalian target of rapamycin; APC; adenomatous polyposis coli; BAFF; B-cell activating factor; COX-2; cyclooxygenase 2; CRC; Colorectal cancer; DD; Dimerization domain; EGFR; epidermal growth
Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signaling
Keywords: CagA; cytotoxin-associated gene A; cagPAI; cytotoxin-associated gene pathogenicity island; cIAP; cellular inhibitor of apoptosis protein; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HBV; hepatitis B virus; HCV; hepatitis C virus; IκBα; NF-kappa-B i
Impact of intracellular ionic strength on dimer binding in the NF-kB Inducing kinase
Keywords: NIK; MAP3K14; Serine-threonine kinase; NF-κB; Signal transduction; Protein-protein interactions; Ionic strength; Structure-activity relationships; Conformational-activity relationships; Homoligomers; Protein dimers; Molecular dynamics simulation;
Transcriptome analysis reveals novel insights into the response of low-dose benzo(a)pyrene exposure in male tilapia
Keywords: TGFi; TGF induced factor homeobox; TGF; transforming growth factor; IL1; interleukin 1; IL1i; IL1 inhibitors; IL1RL1; interleukin 1 receptor like 1; TNF; tumor necrosis factor; Nogo; reticulon 4 (RTN4/Nogo); NGF; nerve growth factor; STC; stanniocalcin 1;
Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling
Keywords: Smac mimetics; Microarray; Breast cancer; Cell death; IAP proteins; Cytokines; AP-1; activator protein 1; BIR; baculovirus IAP repeat; cIAP; cellular IAP; DEG; differential regulated gene; FADD; FAS-associated protein with death domain; FCS; fetal calf se
Full Length ArticleOxidative cracking of vacuum residue with steam over NiK/CeZr-Al catalysts
Keywords: Oxidative cracking; NiK; CeyZr1âyO2-Al2O3; Vacuum residue; Steam;
Immune defects caused by mutations in the ubiquitin system
Keywords: Ubiquitin; nuclear factor κB; immunodeficiency; CVID; Common variable immunodeficiency; DUB; Deubiquitinating enzyme; EDA-ID; Ectodermal dysplasia with immunodeficiency; HECT; Homologous to EGAP C-terminus; HOIL-1; Heme-oxidase iron responsive element bi
Original ArticleOTUD7B and NIK expression in non-small cell lung cancer: Association with clinicopathological features and prognostic implications
Keywords: OTUD7B; NIK; Survival; Prognosis; Lung cancer;
Hierarchical macro–mesoporous Al2O3-supported NiK catalyst for steam catalytic cracking of vacuum residue
Keywords: NiK; Alumina support; Macroporosity; Vacuum residue; Steam; Catalytic cracking
Mangiferin induces apoptosis in multiple myeloma cell lines by suppressing the activation of nuclear factor kappa B-inducing kinase
Keywords: Mangiferin; Multiple myeloma; NIK; NF-κB; ApoptosisMM, multiple myeloma; NF-κB, nuclear factor kappa B; IκB, inhibitor kappa B; IKK, inhibitor kappa B kinase; NIK, nuclear factor kappa B-inducing kinase; AML, acute myeloid leukemia; IAP, inhibitors of apo
The role of IL-18 in type 1 diabetic nephropathy: The problem and future treatment
Keywords: COX-2; cyclooxygenase-2; DN; diabetic nephropathy; ICAM-1; intracellular adhesion molecule-1; IL-18BP; IL-18 binding protein; IRAKs; IL-1R-associated kinases; MAPK; mitogen-activated protein kinase; MCP-1; monocyte chemotactic protein-1; MyD99; myeloid di
Noncanonical NF-κB Signaling in Health and Disease
Keywords: non-canonical NF-κB signaling; NIK; p52/RelB
Mangiferin, a novel nuclear factor kappa B-inducing kinase inhibitor, suppresses metastasis and tumor growth in a mouse metastatic melanoma model
Keywords: NIK; nuclear factor kappa B-inducing kinase; NF-κB; nuclear factor kappa B; IκB; inhibitor of kappa B; IKK; inhibitor of kappa B kinase; ERK1/2; extracellular signal-regulated kinase 1/2; mTOR; mammalian target of rapamycin; MMP; matrix metalloproteinas
The Paracaspase MALT1
Keywords: NF-κB signaling; Protease; Caspase; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1); ABC; activated B cell-like; ABC-DLBCL; activated B cell-like diffuse large B cell lymphoma; Ac; acetyl; ALL; acute lymphomblastic leukemia; AM
Identification of differentially expressed microRNAs involved in non-traumatic osteonecrosis through microRNA expression profiling
Keywords: miRNA, microRNA; ONFH, osteonecrosis of femoral head; qPCR, quantitative polymerase chain reaction; TLR, toll-like receptor; MRIs, magnetic resonance images; H&E, hematoxylin and eosin; GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; NIK
The Nuclear Factor κB pathway: A link to the immune system in the radiation response
Keywords: Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP
Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis
Keywords: NF-κB; Sinomenine; Invasion and metastasis; IKK phosphorylation; CUEDC2; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; EMT; epithelial-mesenchymal transition; IκB; inhibitor of NF-κB; IKK; IκB kinase; pIKK; phosphorylated I
MiRNA in melanoma-derived exosomes
Keywords: Biomarker; Exosome; Melanoma; MicroRNA; MiRNA; AGO-2; argonaute protein 2; BMDCs; bone marrow-derived cells; BMP4; bone morphogenetic protein 4; CCND1; cyclin D1; CDK4; cyclin-dependent kinase; DGCR8; DiGeorge critical region gene 8; EMT; epithelial to me
The intricate interplay between RNA viruses and NF-κB
Keywords: ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;
Styryl-lactone goniothalamin inhibits TNF-α-induced NF-κB activation
Keywords: BSA; bovine serum albumin; EMSA; electrophoretic mobility shift assay; GTN; goniothalamin; IKKβ; inhibitor of κB kinase beta; IL-8; interleukine-8; NF-κB; nuclear factor κB; NIK; NF-κB inducing kinase; PBMC; peripheral blood mononuclear cells; TAB1;
Inhibiting NF-κB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures
Keywords: NIK; Nuclear factor (NF)-κB; p100 processing; 2-Aminopyrimidine;
In vitro anti-inflammatory effect of apigenin in the Helicobacter pylori-infected gastric adenocarcinoma cells
Keywords: AP-1; activator protein 1; CagA; cytotoxin associated antigen; COX-2; cyclooxygenase-2; ERK1/2; extracellular signal regulated kinase 1/2; EtBr; ethidium bromide; H2DCF-DA; dihydrodichlorofluorescein diacetate; HE; dihydroethidium; ICAM-1; intercellular a
Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells
Keywords: AHH; aryl hydrocarbon hydroxylase; ANOVA; analysis of variance; AO/EB; acridine orange/ethidium bromide; CAT; catalase; CCCP; carbonyl cyanide m-chlorophenylhydrazone; COX-2; cyclooxygenase-2; CYP1A1; cytochrome P4501A1; DAB; diaminobenzidine; DCF; 2â²,7
DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication
Keywords: 5â² ppp; 5â² triphosphate; AIM2; Absent In Melanoma 2; ARE; AU-rich element; CARD; Caspase Activation and Recruitment Domains; CDN; cyclic dinucleotide; cGAMP; cyclic-GMP-AMP; cGAS; cGAMP Synthase; CRM1; Chromosome Maintenance Region 1; CstF; Cleavage S
Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response
Keywords: NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro
B-lymphocyte lineage cells and the respiratory system
Keywords: B cells; plasma cells; plasmablasts; respiratory diseases; AID; Activation-induced cytidine deaminase; APRIL; A proliferation-inducing ligand; BAFF; B cell-activating factor of the TNF family; BAL; Bronchoalveolar lavage; BCMA; B-cell maturation antigen
Impact of NF-κB gene polymorphism on allograft outcome in Hispanic renal transplant recipients
Keywords: SNP, single nucleotide polymorphism; NF-κB, nuclear factor kB; NIK, NF-κB inducing kinase; AR, acute rejectionNF-κB1; NF-κB2; NIK; SNP; Gene polymorphisms; Transplantation; Rejection; Survival; Hispanics
Human T Cell Leukemia Virus Type I Tax-Induced IκB-ζ Modulates Tax-Dependent and Tax-Independent Gene Expression in T Cells
Keywords: Abs; antibodies; AP-1; activator protein 1; ATL; adult T cell leukemia; Bcl3; B cell CLL/lymphoma 3; CBB; Coomassie brilliant blue; CREB; cyclic adenosine 3â²,5â²-monophosphate response element-binding protein; EGFP; enhanced green fluorescent protein;
Prolongation of carrageenan-induced inflammation in human colonic epithelial cells by activation of an NFκBâBCL10 loop
Keywords: BCL10; B-cell leukemia/lymphoma 10; CAPE; caffeic phenethyl ester; CARMA; caspase recruitment domain membrane-associated guanylate kinase; CBM; CARMA-BCL10-MALT complex; CGN; carrageenan; ChIP; chromatic immunoprecipitation; DSS; dextran sulfate sodium; H
Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis
Keywords: AdipoR; adiponectin receptor; AMPK; 5â²-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and
A new alternative NF-ΚB Pathway mediated the neuroprotection of GDNF on 6-OHDA-induced DA neurons neurotoxicity
Keywords: GDNF, glial cell line-derived neurotrophic factor; DA, dopaminergic; SNc, substantia nigra pars compacta; NIK, NF-κB-inducing kinase; I B, inhibitor of B; IKK, I B kinase; TH, tyrosine hydroxylaseGDNF; DA neurons; NIK; IKKα; NF-κB
Inhibition of NF-κB1 and NF-κB2 activation in prostate cancer cells treated with antibody against the carboxyl terminal domain of GRP78: Effect of p53 upregulation
Keywords: Anti-GRP78 receptor antibody; Prostate cancer cells; NF-κB1; NF-κB2; Nuclear p53; Cyclin D1; p27kip; P21WAF; Phospho-IKK-α; Phospho-IKKα/β; NIK
Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages
Keywords: COX-2; cyclooxygenase-2; DMEM; Dulbecco's modified Eagle's medium; IKK; IκB kinase; NF-κB; nuclear factor-κB; NIK; NF-κB-inducing kinase; PGN; peptidoglycan; PC-PLC; phosphatidylcholine-phospholipase C; PI-PLC; phosphatidylinositol-PLC; PKC; p
NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening
Keywords: NF-κB inducing kinase; NIK; Virtual screening;
Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-κB pathway
Keywords: ZFP91; p52; NIK; NF-κB; LIGHT; LTβRZFP91, zinc-finger protein 91; NIK, NF-kappa-B inducing kinase; LTβR, lymphotoxin-β receptor; LIGHT, lymphotoxin homolog inducible and competes with HSV glycoprotein D for HveA and is expressed on T-lymphocytes; TNFRSF,
Overexpression of NF-κB inducing kinase underlies constitutive NF-κB activation in lung cancer cells
Keywords: NSCLC; H1299; NF-κB; NIK; RNA interference; mmp-9;