Keywords: Enzyme immobilization; Layered double hydroxides; Nitroreductase; Biohybrid materials; Biomolecules; Mesotrione;
مقالات ISI (ترجمه نشده)
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Keywords: Rosamine; Pyronine-pyridine skeleton; Red emission; Nitroreductase; Mitochondrial targetable;
Keywords: Probe; Fluorescence; Nitroreductase; Small molecule probes;
Keywords: Nitroreductase; Cancer stem cell; Hypoxia; Microenvironment; Two-photon;
Keywords: Naphthalimide; Fluorescent probe; Nitroreductase; Hypoxia;
Keywords: Fluorescent probe; Nitroreductase; Imaging; Hypoxia;
Keywords: Fluorescence probe; Two-photon excited fluorescence; Endoplasmic reticulum; Nitroreductase; Fluorescence imaging;
Keywords: Fluorescent probes; Nitroreductase; Selectivity; Tumor cells; Bioimaging;
Keywords: Azo dyes; Nitro aromatics; Nitroreductase; Azo reductase; Electron shuttle;
Keywords: Nitroreductase; Ames test; Mutagenicity; Nitroimidazole; Nitrofuran; Metabolic rate; Mutagen specific activity; DT-Diaphorase (NQO1); NQO2; Delamanid; Multidrug-resistant tuberculosis; (MDR-TB); Furazolidone; (FZD); Nitrofurantoin; (NIT); Metronidazole; (
Keywords: 2; 4; 6-trinitrotoluene (TNT); Transformation; Bioremediation; Cometabolism; Nitroreductase; Toxicity;
Keywords: Cancer; Target therapy; Prodrug; MDR; Multidrug resistance; ROS; Reactive oxygen species; GSH; Glutathione; ADCs; Antibody-drug conjugates; ADEPT; Antibody-directed enzyme prodrug therapy; GDEPT; Gene-directed enzyme prodrug therapy; HIF; Hypoxia-inducibl
Keywords: EPT; enzyme prodrug therapy; NSC; neural stem cells; MSC; mesenchymal stromal cells; NK; natural killer cells; iPSCs; induced pluripotent stem cells; HSV-TK; herpes simplex virus thymidine kinase; GCV; ganciclovir; 5-FC; 5-Flurocytosine; 5-FU; 5-Flurouric
Keywords: 5-FC; 5-fluorocytosine; 5-FU; 5-fluorouracil; 6-MeP; 6-methylpruine; 6-MeP-dR; 6-methylpurine-2-deoxyriboside; 9-AC; 9-aminocamptothecin; 9-ACG; 9-aminocamptothecin glucuronide; ACV; acyclovir; ADEPT; antibody-directed enzyme prodrug therapy; API; active
Keywords: Nitrogen mustards; NQO1; Nitroreductase; CB 1954; Nitroaromatic prodrugs;
Keywords: Giardia lamblia; Ferredoxin oxidoreductase; Nitroreductase; Nitazoxanide; Metronidazole
Keywords: Enzyme prodrug; Bystander effect; Cancer Gene therapy; GDEPT; Ganciclovir; Nitroreductase; Cytosine deaminase; Thymidine kinase
Keywords: Fluorescent probe; Near-infrared; Ratiometric; Nitroreductase; Cellular imaging;
Keywords: Vetiver; TNT; Phytoremediation; Urea; Nitroreductase
Keywords: Nitroreductase; Fluorescence; Enzyme substrates; Microorganism detection; Bacterial detection;
Keywords: Benzothiadiazole; Hypoxic; Fluorescent probe; Nitroreductase;
Keywords: Chromogenic substrates; Nitroreductase; Phenoxazinones; Microbial identification;
Keywords: ablation; kidney regeneration; nitroreductase; podocyte; zebrafish;
Keywords: Regeneration; Nitroreductase; Zebrafish; Retina; Ablation; Stem cells; Time-lapse;
Keywords: Nitroreductase; Prodrugs; Sulfamethoxazole
A benzothiazole-based water soluble and pH-independent probe for nitroreductase with a dramatic change of chromogenic and fluorogenic properties
Keywords: Benzothiazole; Dual optical change; pH-independent fluorescence; Nitroreductase;
A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging
Keywords: Nitroreductase; MRI contrast agent; Smart imaging probes; Bacterial imaging; Bacterial infection;
Toxic effects and mechanism of 2,2â²,4,4â²-tetrabromodiphenyl ether (BDE-47) on Lemna minor
Keywords: 2,2â²,4,4â²-tetrabromodiphenyl ether (BDE-47); Lemna minor; Toxic effects; Toxic mechanism; Chronic toxicity; Direct toxicity; PBDEs; Polybrominated diphenyl ethers; BDE-47; 2,2â²,4,4â²-tetrabromodiphenyl ether; SOD; superoxide dismutase; POD; peroxid
Characteristics of new bioreductive fluorescent probes based on the xanthene fluorophore: Detection of nitroreductase and imaging of hypoxic cells
Keywords: Xanthene fluorophore; Bioreductive dye; Activity-based fluorescent probe; Nitroreductase; Hypoxia; Imaging of cancer;
A functional and genetic overview of exopolysaccharides produced by Lactobacillus plantarum
Keywords: EPS; exopolysaccharides; SDM; semi-defined medium; MRS; deMan Rogosa Sharpe; Gtf; glycosyl transferase; Act; acyltransferase; CPS; capsular polysaccharide; SPS; slime polysaccharide; LAB; lactic acid bacteria; TNF; tumor necrosis factor; IL; interleukin;
A new aggregation-induced emission fluorescent probe for rapid detection of nitroreductase and its application in living cells
Keywords: Fluorescent probe; Nitroreductase; Aggregation-induced emission; Tetraphenylethene; Hypoxia;
Biotransformation of disperse dyes using nitroreductase immobilized on magnetic particles modified with tosyl group: Identification of products by LC-MS-MS and theoretical studies conducted with DNA
Keywords: Biotransformation; Nitroreductase; Enzyme immobilized onto magnetite; Disperse dyes degradation;
A new fluorescent probe with a large turn-on signal for imaging nitroreductase in tumor cells and tissues by two-photon microscopy
Keywords: Fluorescence Probe; Turn-on; Two-photon; Nitroreductase; Hypoxia; Imaging;
meso-ester BODIPYs for the imaging of hypoxia in tumor cells
Keywords: Bioimaging; BODIPY; Hypoxia; Nitroreductase; Fluorescent turn-on probe;
Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA): Characterization of kinetics and substrate specificity
Keywords: NfsA; Quinones; Nitroaromatic compounds; CB-1954; Bioreductive activation; ArNO2; nitroaromatic compound; FAD; flavin adenine dinucleotide; FMN; flavin mononucleotide; kcat; the apparent catalytic constant; kcat/Km; the bimolecular rate constant in the st
Synthesis and evaluation of 18F-labeled 4-nitrobenzyl derivatives for imaging tumor hypoxia with positron emission tomography: Comparison of 2-[18F]fluoroethyl carbonate and 2-[18F]fluoroethyl carbamate
Keywords: Hypoxia; Positron emission tomography; Fluorine-18; Nitroreductase; 2-Fluoroethanol; 2-Fluoroethylamine;
Biomimetic sensor based on molecularly imprinted polymer with nitroreductase-like activity for metronidazole detection
Keywords: Biomimetic sensor; Molecularly imprinted polymer; Electrochemistry; Metronidazole; Nitroreductase;
Biodegradation of pendimethalin by Bacillus subtilis Y3
Keywords: Pendimethalin; Biodegradation; Bacillus sp. Y3; Metabolic pathway; Nitroreductase
Research ArticleBromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration
Keywords: BEC; biliary epithelial cell; CDE; choline-deficient, ethionine-supplemented; BET; bromodomain and extraterminal domain; HB-LCs; hepatoblast-like cells; LPC; liver progenitor cell; Mtz; metronidazole; DMSO; dimethyl sulfoxide; NTR; nitroreductase; CFP; cy
in vivo imaging and detection of nitroreductase in zebrafish by a new near-infrared fluorescence off-on probe
Keywords: Nitroreductase; Near-infrared fluorescence probe; in vivo imaging; Zebrafish;
Biomimetic sensor based on copper-poly(cysteine) film for the determination of metronidazole
Keywords: Biomimetic sensor; Copper; Electrochemistry; Metronidazole; Nitroreductase;
Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug
Keywords: Bacillus cereus; Nitroreductase; CB1954; Prodrug therapy
Osterix/Sp7 regulates biomineralization of otoliths and bone in medaka (Oryzias latipes)
Keywords: Bmp; bone morphogenetic protein; Col; collagen; Dlx; distal-less gene; Elf; elongation factor; Eya; eyes absent gene; MO; morpholino oligonucleotide; Msx; muscle segment homeobox gene; NFATc1; nuclear factor of activated T cells; nlGFP; nuclear green fluo
Extensive Conversion of Hepatic Biliary Epithelial Cells to Hepatocytes After Near Total Loss of Hepatocytes in Zebrafish
Keywords: Oval Cells; Liver Regeneration; Dedifferentiation; Stem Cells; BEC; biliary epithelial cell; BrdU; bromodeoxyuridine; CFP; cyan fluorescent protein; dpf; days post-fertilization; HB-LCs; hepatoblast-like cells; Mtz; metronidazole; NTR; nitroreductase;
Nitroreductase-activated nitric oxide (NO) prodrugs
Keywords: Nitric oxide; Prodrug; Nitroreductase; Diazeniumdiolate; Directed prodrug therapy;
A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib
Keywords: Prodrug; Colon; Targeting; Nitroreductase; Cancer; Celecoxib; Budesonide; Prednisolone
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A
Keywords: CB1954; PR-104; Nitroreductase; Gene therapy; Nitroaromatic prodrug; SOS chromotest
Design, synthesis, and evaluation of potential prodrugs of DFMO for reductive activation
Keywords: α-Difluoromethylornithine; Nitroreductase; Prodrug design; Reductive activation; Trypanocidal;
Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae
Keywords: 4-NOSO; 4-nitrosoquinoline-N-oxide; 4-NQO; 4-nitroquinoline-Noxide; 4-AQO; 4-aminoquinoline-N-oxide; LC-MS; liquid chromatography-mass spectrometry; Frm2; Nitroreductase; Oxidative stress; 4-NQO; 4-AQO;
Purification and characterization of a nitroreductase from the soil bacterium Streptomyces mirabilis
Keywords: Biotransformation; Nitroreductase; Nitroaromatic compounds; Streptomyces