Keywords: NMDA، N-methyl-d-aspartic acid; Nootropics; Neuropathic pain; GlutamateART, antiretroviral therapy; CCI, chronic constriction injury; CIPN, Chemotherapy Induced Peripheral Neuropathy; ddC, 2′,3′-dideoxycytidine; MIA, sodium monoiodo acetate; NMDA, N-methyl-D-aspartic acid; NSAIDs, non s
مقالات ISI NMDA، N-methyl-d-aspartic acid (ترجمه نشده)
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Keywords: NMDA، N-methyl-d-aspartic acid; AMI, amitriptyline; GABA, gamma-aminobutyric acid; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; Hp, hippocampus; IHP, immunohistochemistry; IR, immunoreactivity; MT, metallothionein; NMDA, N-methyl-d-aspartic acid; NO, nitric oxide; OB, olfactory bulb
Keywords: NMDA، N-methyl-d-aspartic acid; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BIC, bicuculline; ED50, median effective dose; KA, kainic acid; Nic-BZA, nicotinic acid benzylamide; NMDA, N-methyl-d-aspartic acid; PI, protective index; PILO, pilocarpine; PTZ, pentylenetetrazo
Adolescent social defeat alters N-methyl-d-aspartic acid receptor expression and impairs fear learning in adulthood
Keywords: NMDA، N-methyl-d-aspartic acid; NMDA, N-methyl-d-aspartic acid; mPFC, medial prefrontal cortex; CPu, caudate putamen; NAc, nucleus accumbens; CeA, central amygdala; BLA, basolateral amygdala; CA, cornu ammonisNMDA; Adolescence; Stress; Social defeat; Conditioned fear
Hyperforin attenuates microglia activation and inhibits p65-Ser276 NFκB phosphorylation in the rat piriform cortex following status epilepticus
Keywords: NMDA، N-methyl-d-aspartic acid; SE, status epilepticus; BBB, brain–blood barrier; PC, piriform cortex; TNF-α, tumor necrosis factor-α; ET-1, endothelin-1; MIP-2, macrophage inflammatory protein-2; NMDA, N-methyl-d-aspartic acid; TRPC6, transient receptor potential conical channel-6; PB,
Ventral tegmental ionotropic glutamate receptor stimulation of nucleus accumbens tonic dopamine efflux blunts hindbrain-evoked phasic neurotransmission: Implications for dopamine dysregulation disorders
Keywords: NMDA، N-methyl-d-aspartic acid; AMPA, (±)-α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; D2R, D2 autoreceptor; FPA, fixed potential amperometry; iGluR, ionotropic glutamate receptor; LDT, laterodorsal tegmental nucleus; NAc, nucleus accumbens; NMDA, N-methyl-d-aspartic acid; o.d
JAK2 inhibition is neuroprotective and reduces astrogliosis after quinolinic acid striatal lesion in adult mice
Keywords: NMDA، N-methyl-d-aspartic acid; CNS, central nervous system; CNTF, ciliary neurotrophic factor; DMSO, dimethyl sulfoxide; GFAP, glial fibrillary acidic protein; IL-6, interleukin-6; NMDA, N-methyl-d-aspartic acid; QA, quinolinic acid; JAK2, Janus Kinase 2; STAT, signal transducer and ac
Sex, stroke, and inflammation: The potential for estrogen-mediated immunoprotection in stroke
Keywords: NMDA، N-methyl-d-aspartic acid; OGD, oxygen-glucose deprivation; NMDA, N-methyl-d-aspartic acid; estrogen, 17 beta-Estradiol; OVX, ovariectomy; TNF-α, tumor necrosis factor-α; MCP-1, monocyte chemotactic protein-1; ERT, estrogen replacement therapy; MCAO, middle cerebral artery occlusio
nNOS downregulation attenuates neuronal apoptosis by inhibiting nNOS–GluR6 interaction and GluR6 nitrosylation in cerebral ischemic reperfusion
Keywords: NMDA، N-methyl-d-aspartic acid; AS-ODNs, antisense oligonucleotides; GluR6, glutamate receptor 6; IB, immunoblotting; IP, immunoprecipitation; JNK, c-Jun N-terminal kinase; MLK, mixed-lineage kinase; MS-ODNs, missense oligodeoxynucleotides; NMDA, N-methyl-d-aspartic acid; nNOS, neuronal
Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice
Keywords: NMDA، N-methyl-d-aspartic acid; NMDA, N-methyl-d-aspartic acid; dNPA, D.NP(N-Me)AFLFQPQRFamide; NPA-NPFF, NPAFLFQPQRFamide; NPVF, VPNLPQRFamide; SIA, stress-induced analgesiaNeuropeptide FF (NPFF); Forced swimming; Stress-induced analgesia (SIA); Opioid-modulating; Mice
Clozapine decreases exploratory activity and increases anxiety-like behaviour in the Wistar–Kyoto rat but not the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder
Keywords: NMDA، N-methyl-d-aspartic acid; 6-OHDA, 6-hydroxydopamine; ADHD, Attention-deficit/hyperactivity disorder; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; DAT, Dopamine transporter; GABA, γ-aminobutyric acid; NMDA, N-methyl-d-aspartic acid; PFC, Prefrontal cortex; SD, Spragu
Agmatine (decarboxylated l-arginine): Physiological role and therapeutic potential
Keywords: NMDA، N-methyl-d-aspartic acid; ADC, arginine decarboxylase; ODC, ornithine decarboxylase; DAO, diamine oxidase; hOCT1, human organic cation transporter 1; hOCT2, human organic cation transporter 2; hOCT3, human organic cation transporter 3; NMDA, N-methyl-D-aspartic acid; NO, nitric ox
Genomic analysis of [d-Ala2, d-Leu5] enkephalin preconditioning in cortical neuron and glial cell injury after oxygen deprivation
Keywords: NMDA، N-methyl-d-aspartic acid; DADLE, [d-Ala2, d-Leu5] enkephalin; DOR, δ-opioid receptor; ESTs, expressed sequence tags; LDH, Lactate dehydrogenase; MTT, [3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a tetrazole]; NMDA, N-Methyl-d-aspartic acid; OD, oxygen-deprivation
Neuronal nicotinic receptor antagonist reduces anxiety-like behavior in mice
Keywords: NMDA، N-methyl-d-aspartic acid; ACh, acetylcholine; EPM, elevated plus-maze; HPA, hypothalamic–pituitary–adrenal; nAChR, nicotinic acetylcholine receptor; NMDA, N-methyl-d-aspartic acid; OFT, open-field testNicotinic receptor; Anxiety; Lobeline; Mecamylamine; Elevated plus-maze; Mice; M
Cell non-autonomous functions of homeoproteins in neuroprotection in the brain
Keywords: NMDA، N-methyl-d-aspartic acid; CPP, cell penetrating peptide; DA, dopamine; GCL, ganglion cell layer; INL, inner nuclear layer; iPSCs, inducible pluripotent stem cells; mDA, mesencephalic dopaminergic; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridium; NMDA, N-methyl-d-aspartic acid;
Selective knockdown of NMDA receptors in primary afferent neurons decreases pain during phase 2 of the formalin test
Keywords: NMDA، N-methyl-d-aspartic acid; NMDA receptor; dorsal root ganglia; hyperalgesia; nociception; presynapticCGRP, calcitonin gene-related peptide; DMEM, Dulbecco's Modified Eagle's Medium; DRG, dorsal root ganglia; NGF, nerve growth factor; NMDA, N-methyl-d-aspartic acid; NMDAR, NMDA rece
The ERBB4 intracellular domain (4ICD) regulates NRG1-induced gene expression in hippocampal neurons
Keywords: NMDA، N-methyl-d-aspartic acid; 4ICD, ERBB4 intracellular domain; CE, compound E; DIV, day in vitro; ER, endoplasmic reticulum; IHC, immunohistochemistry; IPA, Ingenuity Pathway Analysis; mGlu7, metabotropic glutamate receptor 7; NMDA, N-methyl-d-aspartic acid; NRG1, heregulin β1; RIP,
A novel free radical scavenger rescues retinal cells in vivo
Keywords: NMDA، N-methyl-d-aspartic acid; oxidative stress; neuro-protection; retinal disease; radical scavenger; photoreceptor; ganglion cellBP, 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran; DHE, dihydroethidine; MDA, malondialdehyde; NMDA, N-methyl-d-aspartic acid; ROS, reactiv
Chronic stress-induced hippocampal dendritic retraction requires CA3 NMDA receptors
Keywords: NMDA، N-methyl-d-aspartic acid; HPA axis; CA3; NMDA receptor; chronic stress; dendritic retraction; Golgi stainingANOVA, analysis of variance; CIS, chronic immobilization stress; HPA, hypothalamic-pituitary-adrenal; NMDA, N-methyl-d-aspartic acid; NMDAR, NMDA receptor
Dynamic, experience-dependent modulation of synaptic zinc within the excitatory synapses of the mouse barrel cortex
Keywords: NMDA، N-methyl-d-aspartic acid; barrel cortex; cortical plasticity; ultrastructure; whisker; zincE.M.S., Electron Microscopy Sciences; LTD, long-term depression; LTP, long-term potentiation; NMDA, N-methyl-d-aspartic acid
N-methyl-d-aspartic acid receptors are altered by stress and alcohol in Wistar–Kyoto rat brain
Keywords: NMDA، N-methyl-d-aspartic acid; depression; animal model; [3H] MK-801 binding; glutamateAL, alcohol treatment; BLA, basolateral amygdala; CPu, caudate–putamen; CS, chronic-stress; DA, dopamine; HIP, hippocampus; NAc, nucleus accumbens; NMDA, N-methyl-d-aspartic acid; PFC, prefrontal cor
Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion
Keywords: NMDA، N-methyl-d-aspartic acid; xenon; mice; gender; tMCAO; HIF-1α; AktAkt, protein kinases B; AUC, area under curve; CREB, cyclic AMP, responsive element binding protein; HIF-1α, hypoxia-inducible factor-1α; mTOR, mammalian target of rapamycin; NMDA, N-methyl-d-aspartic acid; PI3K, pho
Transduced PDZ1 domain of PSD-95 decreases Src phosphorylation and increases nNOS (Ser847) phosphorylation contributing to neuroprotection after cerebral ischemia
Keywords: NMDA، N-methyl-d-aspartic acid; Ad, adenovirus; GFP, green fluorescent protein; NMDA, N-methyl-d-aspartic acid; PMSF, phenylmethylsulfonyl; PY, phosphotyrosine; 4-VO, four-vessel occlusion; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; ABC, avidin–biotin complex;
Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity
Keywords: NMDA، N-methyl-d-aspartic acid; NMDA, N-methyl-d-aspartic acid; EAAs, excitatory amino acids; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; DAPI4′, -6-diamidino-2-phenylindole; PV, parvalbumin; CB, calbindin; DAPI-4′, 6-Diamidino-2-Phenylindole Dihydrochloride; ABC, avidi
Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia
Keywords: NMDA، N-methyl-d-aspartic acid; EEG, electroencephalogram; GABA, gamma aminobutyric acid; CA1, cornu ammonis 1 of hippocampus; CA2, cornu ammonis 2 of hippocampus; CA3, cornu ammonis 3 of hippocampus; LC, locus coeruleus; LOD, logarithmic odds; NMDA, N-methyl-d-aspartic acid; S, septal
Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains
Keywords: NMDA، N-methyl-d-aspartic acid; kainate receptor; glycosylation; structural biology; cell surface receptor; synaptic plasticityiGluR, ionotropic glutamate receptor; NMDA, N-methyl-d-aspartic acid; ATD, amino-terminal domain; LBD, ligand binding domain; Endo H, endoglycosidase H; ESI, el
G72 gene is associated with susceptibility to methamphetamine psychosis
Keywords: NMDA، N-methyl-d-aspartic acid; DTNBP1, dystrobrevin-binding protein 1; GRM3, metabotropic glutamate receptor 3; DAOA, d-amino acid oxidase activator; NMDA, N-methyl-D-aspartic acid; SNP, single nucleotide polymorphism; DAAO, D-amino acid oxidase; JGIDA, the Japanese Genetics Initiative
Pharmacological screening of Malian medicinal plants used against epilepsy and convulsions
Keywords: NMDA، N-methyl-d-aspartic acid; aCSF, artificial cerebrospinal fluid; GABA, γ-aminobutyric acid; NMDA, N-methyl-d-aspartic acid; PTZ, pentylenetetrazol; SEDs, spontaneous epileptiform dischargesCortical wedge preparation; Epilepsy; GABA; Malian traditional medicine
Low in vivo brain glucose consumption and high oxidative stress in accelerated aging
Keywords: NMDA، N-methyl-d-aspartic acid; SAMR, senescence accelerated mice resistant; SAMP, senescence accelerated mice prone; NMDA, N-methyl-d-aspartic acid; ROS, reactive oxygen species; PMA, phorbol 12-myristate 13-acetateAging; Positron emission tomography; Stem cells; Free radicals
Functional differences between D1 and D5 revealed by high resolution imaging on live neurons
Keywords: NMDA، N-methyl-d-aspartic acid; D1; D5; NMDA receptor; lateral diffusion; spines; PSD-95FRAP, fluorescence recovery after photobleaching; GPCR, G-protein coupled receptor; GST, glutathione S-transferase; NMDA, N-methyl-d-aspartic acid; PSD-95, postsynaptic density-95
Somatostatin receptors in the nucleus accumbens modulate dopamine-dependent but not acetylcholine-dependent turning behaviour of rats
Keywords: NMDA، N-methyl-d-aspartic acid; nucleus accumbens; turning behaviour; dopamine receptors; somatostatin receptors; ratsAMPA, α-amino-3-hydro-methyl-4-isoxazolpropionic acid; ANOVA, analysis of variance; GABA, γ-aminobutyric acid; Nacc, nucleus accumbens; NMDA, N-methyl-d-aspartic acid; S
Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis
Keywords: NMDA، N-methyl-d-aspartic acid; AD, Alzheimer's disease; Ibo model, ibotenic acid induced memory deficient model; ChAT, choline acetyl transferase; GAD65/67, glutamic acid decarboxylase 65/67; NMDA, N-methyl-d-aspartic acid; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: Implications for seizure susceptibility
Keywords: NMDA، N-methyl-d-aspartic acid; astrocytes; AMPA; cytokines; inflammation; NMDA; kainate receptorsAP-5, 2-amino-5-phosphopentanoic acid; NBQX, 6-nitro-7-sulfamoyl-benzo(f)quinoxaline-2,3-dione; NMDA, N-methyl-d-aspartic acid; TNF-alpha, tumor necrosis factor-alpha
Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions
Keywords: NMDA، N-methyl-d-aspartic acid; Nrg1, neuregulin-1; NMDA, N-methyl-d-aspartic acid; PPI, pre-pulse inhibition; MMN, mismatch negativity; ERP, event-related potentialNeuregulin; Schizophrenia; Mice; Animal model; Event-related potential; Social; Behavior
Protease-activated receptors as drug targets in inflammation and pain
Keywords: NMDA، N-methyl-d-aspartic acid; CGRP, calcitonin gene-related peptide; DSS, dextran sodium sulfate; IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; IL, interleukin; MMP, matrix metalloprotease; NMDA, N-methyl-D-aspartic acid; PAR, protease-activated receptor; PKA, protei
The effect of extracts of Searsia species on epileptiform activity in slices of the mouse cerebral cortex
Keywords: NMDA، N-methyl-d-aspartic acid; GABA, γ-aminobutyric acid; NMDA, N-methyl-d-aspartic acid; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; aCSF, artificial cerebrospinal fluid; SEDs, spontaneous epileptiform dischargesCortical wedge preparation; NMDA receptor antagonist; Sea
mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo
Keywords: NMDA، N-methyl-d-aspartic acid; CNS, central nervous system; mGlu, metabotropic glutamate; mGluR1, mGlu receptor subtype 1; mGluR5, mGlu receptor subtype 5; (S)-3,5-DHPG, (S)-3,5-dihydroxyphenylglycine; NMDA, N-methyl-d-aspartic acid; PKC, protein kinase C; PKA, protein kinase A; ED50,
Co-activation of GABA receptors inhibits the JNK3 apoptotic pathway via the disassembly of the GluR6-PSD95-MLK3 signaling module in cerebral ischemic-reperfusion
Keywords: NMDA، N-methyl-d-aspartic acid; NMDA, N-methyl-d-aspartic acid; GABA, γ-amino butyric acidCerebral ischemia; Muscimol; Baclofen; JNK pathway; Neuroprotection
A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons
Keywords: NMDA، N-methyl-d-aspartic acid; BSO, L-buthionine-(S,R)-sulfoximine; DA, dopamine; GSH, glutathione; GSHEE, GSH-ethyl-ester; L-type channels, voltage-gated L-type calcium channels; NMDA, N-methyl-D-aspartic acid; NR1, subunit NR1 of NMDA receptor; RyRs, ryanodine receptors; TTX, tetrodo
Protective action of honokiol, administered orally, against oxidative stress in brain of mice challenged with NMDA
Keywords: NMDA، N-methyl-d-aspartic acid; Honokiol; NMDA; Neuroprotection; Glutathione; Lipid peroxidationHK, honokiol; GSH, glutathione; NMDA, N-methyl-d-aspartic acid; TBARS, thiobarbituric acid-reactive substances; ICR, Institute of Cancer Research; i.p., intraperitoneally
Antimanic therapies target brain arachidonic acid signaling: Lessons learned about the regulation of brain fatty acid metabolism
Keywords: NMDA، N-methyl-d-aspartic acid; Acsl, acyl-CoA synthetase; AP, activator protein; cPLA2, cytosolic phospholipase A2; COX, cyclooxygenase; DHA, docosahexaenoic acid; GRE, glucocorticoid response element; NMDA, n-methyl-d-aspartic acid; NF-κB, nuclear factor kappa B; PLA2, phospholipase A
Specific blockade of morphine- and cocaine-induced reinforcing effects in conditioned place preference by nitrous oxide in mice
Keywords: NMDA، N-methyl-d-aspartic acid; cocaine; morphine; nitrous oxide; reward; place conditioningANOVA, analysis of variance; CPP, conditioned place preference; NMDA, N-methyl-D-aspartic acid; N2O, nitrous oxide
Imaging signal transduction via arachidonic acid in the human brain during visual stimulation, by means of positron emission tomography
Keywords: NMDA، N-methyl-d-aspartic acid; AA, arachidonic acid; BA, Brodmann area; LED, light emitting diode; MRI, magnetic resonance imaging; NMDA, N-methyl-d-aspartic acid; PET, positron emission tomography; PGE2, prostaglandin E2; PLA2, phospholipase A2; cPLA2, cytosolic PLA2; SPM, statistical
Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia
Keywords: NMDA، N-methyl-d-aspartic acid; APD, antipsychotic drug; DLPFC, dorsolateral prefrontal cortex; qPCR, quantitative polymerase chain reaction; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; NMDA, N-methyl-D-aspartic acid; GRIA, glutamate receptor ionotropic AMPA; B2M, β-2 mi
Hippocampal formation: Shedding light on the influence of sex and stress on the brain
Keywords: NMDA، N-methyl-d-aspartic acid; AR, androgen receptor; EAA, excitatory amino acids; ER, estrogen receptor; mPFC, medial prefrontal cortex; NGF, nerve growth factor; NMDA, N-methyl-d-aspartic acid; PR, progestin receptor; RVLM, rostral ventrolateral medulla; TH, tyrosine hydroxylase; TPH
Genistein inhibits glutamate-induced apoptotic processes in primary neuronal cell cultures: An involvement of aryl hydrocarbon receptor and estrogen receptor/glycogen synthase kinase-3β intracellular signaling pathway
Keywords: NMDA، N-methyl-d-aspartic acid; phytoestrogen; SERM; apoptosis; excitotoxicity; brain tissuesDIV, days in vitro; DMSO, dimethyl sulfoxide; GSK-3β, glycogen synthase kinase-3β; LDH, lactate dehydrogenase; MAPK, mitogen-activated protein kinase; NMDA, N-methyl-d-aspartic acid; PBS, phosph
Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation
Keywords: NMDA، N-methyl-d-aspartic acid; 3-AB, 3-aminobenzamide; AIF, apoptosis inducing factor; LPS, lipopolysaccharide; NAD, nicotinamide adenine dinucleotide; NF-κB, nuclear factor-κB; NMDA, N-methyl-d-aspartic acid; NOS, nitric oxide synthase; PAR, poly(ADP-ribose); PARP-1, poly(ADP-ribose)
Activation of α2-adrenoceptors in the trigeminal region produces sex-specific modulation of nociception in the rat
Keywords: NMDA، N-methyl-d-aspartic acid; α2-adreoceptors; analgesia; estrogen; pain; sex differencesANOVA, analysis of variance; DiE, diestrous; GIRK2, G protein-coupled inwardly rectifying potassium channel 2; GPCR, G protein-coupled receptor; KF, Kölliker-Fuse; NMDA, N-methyl-d-aspartic acid;
Short-term plasticity in excitatory synapses of the rat medial preoptic nucleus
Keywords: NMDA، N-methyl-d-aspartic acid; AMPA, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; eEPSC, evoked excitatory postsynaptic current; GABAA, γ-aminobutyric acidA; IPI, intra-pair interval; ISI, inter-stimulus interval; MPN, medial preoptic nucleus; NMDA, N-methyl-d-aspartic acid; P
Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices
Keywords: NMDA، N-methyl-d-aspartic acid; AP5, d-(−) 2-amino-5-phosphonopentanoic acid; 2-APB, 2-aminoethoxydiphenyl borane; NMDA, N-methyl-d-aspartic acid; TRP, transient receptor potential (channel); Rin, input resistance; Gin, input conductance; VSCC, voltage-sensitive calcium channelHippocamp