A placebo controlled trial for an NMO relapse prevention treatment: Ethical considerations
Keywords: Research ethics; Placebo controlled trial; Justice; Evidence; NMO;
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Neuromyelitis optica in Portugal (NEMIPORT) – A multicentre study
Keywords: NMO; Neuromyelitis optica; Aquaporin 4; AQP4; Autoimmune disorders
Familial forms of multiple sclerosis and neuromyelitis optica at an MS center in Rio de Janeiro State, Brazil
Keywords: Familial form; Multiple sclerosis; Neuromyelitis optica; Aquaporin-4; NMO; NMO spectrum; Concordance; Brazil; Latin America;
Immunogenetics of autoimmune thyroid diseases: A comprehensive review
Keywords: Autoimmune thyroid disease; Graves' disease; Hashimoto's thyroiditis; Autoimmunity; Immunogenetics; Polymorphism; TSHR; thyrotropin receptor; FOXP3; forkhead box P3; CTLA-4; cytotoxic T-lymphocyte-associated molecule-4; PTPN22M; protein tyrosine phosphata
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3
Keywords: ADT; androsterone; AR; androgen receptor; Ar; aryl group; DBD; DNA binding domain; DCM; dichloromethane; DHT; dihydrotestosterone; DIPEA; N,N-diisopropylethylamine; DMF; dimethylformamide; DMSO; dimethylsulfoxide; Î4-dione; 4-androstene-3,17-dione; EtOAc
Lack of association between AQP4 polymorphisms and risk of inflammatory demyelinating disease in a Korean population
Keywords: SNP; single nucleotide polymorphism; CNS; central nervous system; IDD; inflammatory demyelinating disease; MS; multiple sclerosis; NMO; neuromyelitis optica; AQP4; aquaporin 4; AQP4; Inflammatory demyelinating disease; Multiple sclerosis; Neuromyelitis op
Elevated antibody reactivity to measles virus NCORE protein among patients with multiple sclerosis and their healthy siblings with intrathecal oligoclonal immunoglobulin G production
Keywords: MS; multiple sclerosis; OCB; oligoclonal bands; MS OCB trait; multiple sclerosis oligoclonal band trait; IgG; immunoglobulin G; CSF; cerebrospinal fluid; NCORE; N-terminal portion of the measles nucleocapsid protein; CNS; central nervous system; MRZ; meas
MRI characteristics of periaqueductal lesions in multiple sclerosis
Keywords: CIS; clinically isolated syndrome; DIR; double inversion recovery; EDSS; expanded disability status scale; FS; functional system; MRI; magnetic resonance image; MS; multiple sclerosis; NMO; neuromyelitis optica; NRS; numerical rating scale; PAG; periaqued
Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59
Keywords: NMO; Aquaporin-4; Astrocyte; Complement-dependent cytotoxicity; Demyelination
Aquaporin and brain diseases
Keywords: AQP; aquaporin; Kir4.1; inwardly rectifying potassium channel 4.1; OAP; orthogonal array of particles; DWI; diffusion weighted imaging; T2WI; T2-weighted imaging; DTI; diffusion tensor imaging; ADC; apparent diffusion coefficient; MRI; magnetic resonance
IL-22 secreting CD4Â + T cells in the patients with neuromyelitis optica and multiple sclerosis
Keywords: IL-22 secreting CD4Â + T cells; Th22 cells; IL-22; NMO; MS;
Clinical and immunological follow-up of B-cell depleting therapy in CNS demyelinating diseases
Keywords: NMO; LETM; B cells; Rituximab; Aquaporin-4; BAFF;
Aquaporin-4 antibodies, CNS acidosis and neuromyelitis optica: A potential link
Keywords: Ab; antibodies; AQP4; aquaporin-4; BBB; blood-brain barrier; CSF; cerebrospinal fluid; CNS; central nervous system; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IgG; immunoglobulin G; NMO; neuromyelitis optica; SLE; systemic lupus
Synthesis and evaluation of N8-acetylspermidine analogues as inhibitors of bacterial acetylpolyamine amidohydrolase
Keywords: APAH; acetylpolyamine amidohydrolase; dppm; bis(diphenylphosphino)methane; 9-BBN; 9-borabicyclo[3.3.1]nonane; DMP; Dess-Martin periodinane; DFMO; α-difluoromethylornithine; Boc2O; di-tert-butyl pyrocarbonate; ESI; electrospray ionization; HRMS; high-re
Optic neuritis in neuromyelitis optica
Keywords: NMO; Optic nerve; Aquaporin-4; Devic's disease; Neuroinflammation; ADCC; antibody-dependent cell-mediated cytotoxicity; AQP4; aquaporin-4; BBB; blood-brain barrier; CDC; complement-dependent cytotoxicity; CDCC; complement-dependent cell-mediated cytotox
Intractable Nausea and Vomiting From Autoantibodies Against a Brain Water Channel
Keywords: Diagnosis; Chronic Nausea and Vomiting; Central Nervous System; Aquaporin-4 Antibody; AQP4; aquaporin-4; AQP4-IgG; immunoglobulin G against AQP4; CT; computed tomography; EAAT2; excitatory amino acid transporter 2; LETM; longitudinally extensive transvers
[18F]-Fluorodeoxyglucose-Positron Emission Tomography in Patients With Active Myelopathy
Keywords: CSF; cerebrospinal fluid; CT; computed tomography; FDG; [18F]-fluorodeoxyglucose; MRI; magnetic resonance imaging; MS; multiple sclerosis; NMO; neuromyelitis optica; PET; positron emission tomography; SUVmax; maximum standardized uptake value;
A case of ADEM with atypical MRI findings of a centrally-located long spinal cord lesion
Keywords: ADEM; Centrally located long spinal cord lesion (LCL); NMO
Diffusion tensor imaging characterization of occult brain damage in relapsing neuromyelitis optica using 3.0T magnetic resonance imaging techniques
Keywords: CSF; cerebrospinal fluid; DTI; diffusion tensor imaging; EDSS; Expanded Disability Status Scale; FA; fractional anisotropy; fMRI; functional MRI; MD; mean diffusivity; MTI; magnetization transfer imaging; NMO; neuromyelitis optica; RNMO; relapsing neuromy
Testing for antibodies to human aquaporin-4 by ELISA: Sensitivity, specificity, and direct comparison with immunohistochemistry
Keywords: AQP4; aquaporin-4; AQP4-Ab; antibodies to aquaporin-4; ELISA; enzyme-linked immunosorbent assay; HC; healthy controls; IHC; immunohistochemistry; LETM; longitudinally extensive myelitis; MS; multiple sclerosis; NMO; neuromyelitis optica; NMO-IgG; neuromye
Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis
Keywords: NMO; MS; SLE; Interferon; STAT1; MxA
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): A misdiagnosed disease entity
Keywords: ACE; Angiotensin Converting Enzyme (sarcoidosis); AD; Alzheimer's disease; CADASIL; Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy; CSF; Cerebrospinal fluid; HIV; Human immunodeficiency virus; MS; Multiple Scler
A novel synthesis of fluorine-containing cyclopentenones via Pauson–Khand reaction
Keywords: Fluorine-containing cyclopentenone; Pauson–Khand; NMO; TMANO
Synthesis and P2Y2 receptor agonist activities of uridine 5â²-phosphonate analogues
Keywords: NBS; N-bromosuccinimide; TMSBr; trimethylsilyl bromide; TFA; trifluoroacetic acid; NMO; N-methylmorpholine-N-oxide; P2Y2 receptor; G protein-coupled receptor; Uracil nucleotides; Nucleoside phosphonates; Partial agonists;
Neuromyelitis Optica Spectrum Disorder as an Initial Presentation of Primary Sjögren's Syndrome
Keywords: Sjogren's syndrome; myelitis; neuromyelitis optica; Devic's disease; NMO; aquaporin-4
T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement
Keywords: Aquaporin-4; Devic's syndrome; NMO; Lymphocytes; T cells
Orthogonal array formation by human aquaporin-4: Examination of neuromyelitis optica-associated aquaporin-4 polymorphisms
Keywords: NMO; AQP4; Water channel; Neuroinflammation
A comparison of DNA damage induced by aflatoxin B1 in hepatocyte-like cells, their progenitor mesenchymal stem cells and CD34+ cells isolated from umbilical cord blood
Keywords: AFB1; Aflatoxin B1; AU; Arbitrary unit; CYP; Cytochrome P450; IC50; Inhibitory concentration; DMSO; Dimethylsulfoxide; hBMSCs; Human bone marrow mesenchymal stem cells; UCB; Umbilical cord blood; BSA; Bovine serum albumin; SCF; Stem cell factor; TPO; Thro
Strategy for anti-aquaporin-4 auto-antibody identification and quantification using a new cell-based assay
Keywords: NMO; neuromyelitis optica; NMOSD; NMO spectrum disorders; LETM; longitudinally extensive transverse myelitis; MS; multiple sclerosis; CIS; clinically isolated syndrome; AQP4; aquaporin-4; CNS; central nervous system; BBB; blood-brain barrier; CBA; cell-
Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: Results from 211 lumbar punctures
Keywords: AQP4; aquaporin-4; AQP4-Ab; aquaporin-4 antibody; CBA; cell based assay; CSF; cerebro-spinal fluid; IHC; immunohistochemistry; LETM; longitudinally extensive transverse myelitis; LP; lumbar puncture; NMO; neuromyelitis optica; NMOSD; neuromyelitis optica
Synthesis, characterization, and catalytic applications of Ru(III) complexes containing N-[di(alkyl/aryl)carbamothioyl]benzamide derivatives and triphenylphosphine/triphenylarsine
Keywords: Ruthenium(III); Triphenylphosphine; OS donor ligand; Catalytic oxidation; NMO
Higher order structure of aquaporin-4
Keywords: aquaporins; AQP4; BN–SDS/PAGE; NMO; NMO-IgG; OAPsAQP, aquaporin; AQP4, aquaporin-4; BBB, blood-brain barrier; BNE, blue native electrophoresis; CNS, central nervous system; DAPs, dystrophin associated proteins; DDM, dodecyl-beta-d-maltoside; DMD, Duchenne
Aquaporins in spinal cord injury: the janus face of aquaporin 4
Keywords: human spinal cord injury; AQP4-negative astrocytes; AQP4-overexpressing astrocytes; bumetanide; pain; fluid-filled cavity; ALS; amyotrophic lateral sclerosis; AQPs; aquaporins; AQP4; aquaporin 4; ARE; antioxidant-responsive element; BBB; Basso, Beattie, B
Identification of binding sites for anti-aquaporin 4 antibodies in patients with neuromyelitis optica
Keywords: Anti-aquaporin-4 antibodies; NMO; Chimera mutant AQP4; Epitope; Extracellular domain
Occurrence, biological activity and synthesis of cheilanthane sesterterpenoids
Keywords: Cheilanthanes; Sesterterpenoids; Marine natural products; Synthesis; Ac; acetyl; n-Bu; n-butyl; CSA; camphorsulfonic acid; m-CPBA; m-chloroperbenzoic acid; DBU; 1,8-diazobicyclo[5.4.0]undec-7-ene; DCC; 1,3-dicyclohexylcarbodiimide; DHP; 3,4-dihydro-2H-pyr
Disseminated encephalomyelitis in adults
Keywords: Disseminating encephalomyelis; Acute disseminating encephalomyelitis recurrent; Multiphasic DEM; NMO
Advances in the Baylis-Hillman reaction-assisted synthesis of cyclic frameworks
Keywords: Baylis-Hillman reaction; Cyclic compounds; Heterocycles; Nucleophilic substitution; Ac; acetyl; AIBN; 2,20-azobisisobutyronitrile; Aq; aqueous; Ar; aryl; 9BBN; 9-borabicyclo[3.3.1]nonane; BINAP; 2,20-bis(diphenylphosphanyl)-1,10-binaphthyl; BF3·Et2O; b
Asymmetric organocatalysis
Keywords: Ac; acetyl; Ar; aryl; BINOL; 1,1â²-bi-2-naphthol; Bn; benzyl; Boc; tert-butoxycarbonyl; Bu; butyl; Bz; benzoyl; Cbz; benzyloxycarbonyl; CPME; cyclopentyl methyl ether; Cy; cyclohexyl; DABCO; 1,4-diazabicyclo[2.2.2]octane; DBAB; dibenzylazodicarboxylate;
Enantioselective synthesis of steroids
Keywords: Steroids; Asymmetric inductions; Pool chiral; Enantioselectivity; Resolution; acac; acetylacetonate; 9-BBN; 9-bora-bicyclo[3.3.1]nonane; BHT; 2,6-di-tert-butyl-4-methylphenol; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthyl; Binol; 1,1â²-binaphtha
Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles
Keywords: Azaspirocyclic ring systems; Spirocycles; 3° Carbon center; Ac; acetyl; AIBN; azobisisobutyronitrile(2,2â²-azo(2-methylpropionitrile)); Ar; aryl; Bn; benzyl; Boc; t-butoxycarbonyl; Bu; butyl; Cbz; benzyloxycarbonyl; Cy; cyclohexyl; DBB; di-t-butylbiphen
Recent advances in the chemistry of macroline, sarpagine and ajmaline-related indole alkaloids
Keywords: Ac; acetyl; AD; asymmetric dihydroxylation; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; 9-BBN; 9-borabicyclo[3.3.1]nonane; Bn; benzyl; Boc; tert-butoxycarbonyl; Bu; butyl; Bz; benzoyl; cat; catalytic; CBz; benzyloxycarbonyl; CLB; chlorobenzoyl; Cy; cyc
Synthesis of amino- and diaminoconduritols and their applications
Keywords: Conduritols; Conduramines; Diaminoconduritols; Asymmetric synthesis; Ac; acetyl; aq; aqueous; AIBN; 2,2â²-azobis(isobutyronitrile); Bn; benzyl; Boc; tert-butyloxycarbonyl; n-Bu; n-butyl; s-Bu; sec-butyl; t-Bu; tert-butyl; Bz; benzoyl; CAN; ceric ammonium
Use of chiral sulfoxides in asymmetric synthesis
Keywords: Ac; acetyl; Acac; acetylacetone; AIBN; 2,2â²-azobisisobutyronitrile; Ar; aryl; BF3·Et2O; boron trifluoride etherate; BINAP; 2,2â²-bis(diphenylphosphanyl)-1,1â²-binaphthyl; Bn; benzyl; Boc; tert-butoxycarbonyl; Born; borneol; Bu; butyl; Cbz; benzyloxyc
A synthon approach to spiro compounds
Keywords: Photochromism; Synthon; Spiro compounds; BINAP; 2,2â²-bis(diphenylphospospiro)-1,1â²-binaphthalene; Boc; t-butoxycarbonyl; CTAB; cetyltrimethylammonium bromide; DEAD; diethylazodicarboxylate; 4-DMAP; 4-(dimethylamino)pyridine; Fmoc; 9-fluorenylmethoxyca
2004 Pathogenesis of Rare Neuroimmunologic Disorders, Hyatt Regency Inner Harbor, Baltimore, MD, August 19th 2004-August 20th 2004
Keywords: ADEM; Acute disseminated encephalomyelitis; AchR; Acetylcholine receptor; ALD; Adrenoleukodystrophy; ALDP; Protein encoded by X-ALD gene ABCD1; AMAN; Acute motor axonal neuropathy; APC; Antigen presenting cell; APL; Altered peptide ligand; C. jejuni; Camp
Naphtho[2,3-c]furan-4,9-diones and related compounds: theoretically interesting and bioactive natural and synthetic products
Keywords: Naphtho[2,3-c]furan-4,9-diones; Naphtho[2,3-c]furan-4(9H)-ones; Naphtho[2,3-c]furan; Isofuranonaphthoquinones; Ac; acetyl; AIBN; 2â²-azobis(isobutyronitrile); Ar; aryl; Bn; benzyl; BOM; benzyloxymethyl; But; tert-butyl; CSA; camphor-10-sulfonic acid; DBU
Recent advances in ether dealkylation
Keywords: O-Dealkylation; Deprotection; Debenzylation; Review; Ac; acetyl; Alloc/Aloc; allyloxycarbonyl; BMIM; 1-n-butyl-3-imidazolium; Bn; benzyl; Boc; t-butoxycarbonyl; BOM; benzyloxymethyl; Bz; benzoyl; CAN; ceric ammonium nitrate; Cbz; benzyloxycarbonyl; CSI; c
Chemical and biochemical transformations in ionic liquids
Keywords: Hacac; Acetylacetone; [R(Rf)taz][Y]; 1,4-Alkyl(polyfluoroalkyl)-1,2,4-triazolium ionic liquids; [taz][X]; 1-Alkyl-4-polyfluoroalkyl-1,2,4-triazolium halides; (DHQ)2PHAL; 1,4-Bis(9-O-dihydroquininyl)phthalazine; (DHQD)2PHAL; 1,4-Bis(9-O-dihydroquinidinyl)p
Use of O-glycosylation in total synthesis
Keywords: O-Glycosylation; Total synthesis; Ac; acetyl; ACF; activated carbon fiber; AIBN; 2,2â²-azobiisobutyronitrile; Alloc; allyloxycarbonyl; Ar; aryl; AtOH; 7-aza-1-hydroxy-1H-benzotriazole; BF3(Et2O); boron trifluoride etherate; DMB; 3,4-dimethoxybenzyl; DMTS