Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase
Keywords: Antiviral; HIV-1; NNRTI; Triazole; K103N; Y181C; Y188L
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Inhibition of endogenous reverse transcription of human and nonhuman primate lentiviruses: Potential for development of lentivirucides
Keywords: HIV-1; SIV; NERT; NRTI; NNRTI; RT; Virucide
Aspects of successful drug discovery and development
Keywords: Chemotherapy; NNRTI; Protease inhibitor; HIV; Drug development
Response of HIV positive patients to the long-term salvage therapy by lopinavir/ritonavir
Keywords: 3TC; lamivudin; ABC; abacavir; AZT; azidothymidin (zidovudin); d4Tstavudin; ddC; dideoxycytidin (zalcitabin); ddI; dideoxyinosin (didanosin); EFV; efavirenz; HAART; highly active antiretroviral therapy; IDV; indinavir; LPV; lopinavir; LPV/r; combination o
Understanding Patient Preferences for HIV Medications Using Adaptive Conjoint Analysis: Feasibility Assessment
Keywords: conjoint; HIV therapy; NNRTI; protease inhibitors;
Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: A dual mechanism approach
Keywords: hTR; human telomerase RNA component; TP1; telomerase-associated protein 1; hTERT; human telomerase reverse transcriptase; PUFAs; polyunsaturated fatty acids; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; LDH; lactate dehydrogenase; PBS; phosphate
Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART
Keywords: HIV-1; human immunodeficiency virus type 1; HAART; highly active antiretroviral therapy; PBMC; peripheral blood mononuclear cells; BDL; below detectable level; Pr; protease; RT; reverse transcriptase; PI; protease inhibitor; NRTI; nucleoside reverse trans
Development of an assay method for the detection and quantification of protease and non-nucleoside reverse transcriptase inhibitors in plasma and in peripherical blood mononuclear cells by liquid chromatography coupled with ultraviolet or tandem mass spec
Keywords: PI; NNRTI; LC-UV; LC-MS/MS; Plasma; Intracellular;
Cell-based and biochemical screening approaches for the discovery of novel HIV-1 inhibitors
Keywords: beta-Gal; beta-galactosidase; CAT; chloramphenicol acetyltransferase; CHO; Chinese Hamster Ovary; CV-N; cyanovirin-N; dsDNA; double-stranded DNA; Ec; ecdysone; EIA; enzyme immunoassay; ELISA; enzyme-linked immunosorbent assay; Env; envelope; FLIPR; Fluoro
Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
Keywords: Dapivirine; TMC120-R147681; Drug design; Drug resistance; Etravirine; TMC125-R165335; 3DSAR; Three-dimensional structure-activity relationships; DAPY; Diarylpyrimidine; DATA; Diaryltriazine; dsDNA; Double-stranded DNA; HAART; Highly active antiretroviral