دانلود مقالات ISI درباره Nnrti + ترجمه فارسی

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase

Keywords: Anti-HIV agents; Non-nucleoside inhibitors of HIV reverse transcriptase; Computer-aided drug design; NNRTI; Dimeric inhibitors

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

NNRTIs: Future prospects

Keywords: Efavirenz; NNRTI; NevirapineÉfavirenz; INNTI; Névirapine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Development and evaluation of an assay for HIV-1 protease and reverse transcriptase drug resistance genotyping of all major group-M subtypes

Keywords: ART; antiretroviral therapy; DBS; dried blood spot; LOD; limit of detection; NNRTI; non-nucleoside reverse transcriptase inhibitor; NRTI; nucleoside reverse transcriptase inhibitor; Nt; nucleotide; PI; protease inhibitor; PMTCT; prevention-of-mother-to-ch

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of lersivirine co-administration on pharmacokinetics of methadone in healthy volunteers

Keywords: HIV; Lersivirine; NNRTI; Methadone; Interaction; Opioid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

HIV-1 mother-to-child transmission and drug resistance among Brazilian pregnant women with high access to diagnosis and prophylactic measures

Keywords: HIV-1; human immunodeficiency virus type 1; MTCT; mother-to-child transmission; ARV; antiretroviral; PPPW; Program for the Protection of Pregnant Women; HAART; highly active antiretroviral therapy; NRTI; nucleoside reverse-transcriptase inhibitors; NNRTI;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba

Keywords: ART; antiretroviral therapy; CI; confidence interval; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside RTI; PI; protease inhibitor; FCR; full-class resistance; CRF; circulating recombinant form; HIV; human immunodeficiency virus; MD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents

Keywords: CCR5; CC chemokine receptor type 5; CXCR4; CXC chemokine receptor type 4; MAGI; Multinuclear activation of a galactosidase indicator; NNRTI; Non-nucleoside reverse transcriptase inhibitors; NRTI; Nucleoside reverse transcriptase inhibitors; Anti-HIV agent

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A pyrophosphatase activity associated with purified HIV-1 particles

Keywords: Retrovirus; Reverse transcription; Resistance; Excision; Pyrophosphorolysis; HIV-1; human immunodeficiency virus type 1; RT; reverse transcriptase; AZT; 3′-azido-3′-deoxythymidine, zidovudine; d4T; 2′-3′-didehydro-2′-3′-dideoxythymidine; TAM;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz

Keywords: EFV; Efavirenz; HAART; highly active antiretroviral therapy; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; ROS; reactive oxygen species; ΔΨm; mitochondrial transmembrane potential; DNA; polymera

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors

Keywords: Combinatorial design; Diversity selection HIV-1; NNRTIs HEPT; Antiviral activity; RHHROCXXJZOAGP-UHFFFAOYSA-N; KMCGFILCIRJEHJ-UHFFFAOYSA-N; XXFUGXPQNOZBIR-UHFFFAOYSA-N; OFOHDLYVTOWSFB-UHFFFAOYSA-N; PWAKKEPZIWJVBA-UHFFFAOYSA-N; DTCUBSJAMNGQFU-UHFFFAOYSA-N;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Predicted susceptibility of etravirine in HIV patients experiencing virological failure secondary to non-nucleoside reverse transcriptase inhibitor resistance in Argentina

Keywords: Etravirine; HIV resistance; NNRTI; Argentina; Etravirina; Resistencia VIH; NNRTI; Argentina;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Short CommunicationAntiviral interactions of combinations of highly potent 2,4(1H,3H)-pyrimidinedione congeners and other anti-HIV agents

Keywords: NNRTI; HIV-1; Combination therapy; Pyrimidinedione;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

HIV-1 genetic diversity and drug resistance among treatment naïve patients from Southern Brazil: An association of HIV-1 subtypes with exposure categories

Keywords: AIDS; acquired immune deficiency syndrome; ARV; antiretroviral; CPR; calibrated population resistance tool; CRF; circulating recombinant form; DRMs; drug resistance mutations; INT; integrase; INTI; integrase inhibitors; HIV; human immunodeficiency virus;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Vitamin D Supplementation and CD4 Count in Children Infected with Human Immunodeficiency Virus

Keywords: 25(OH)D; 25-hydroxyvitamin D; 1,25(OH)2D; 1,25-dihydroxyvitamin D; cART; Combination antiretroviral therapy; CDC; Centers for Disease Control and Prevention; HIV; Human immunodeficiency virus; NNRTI; Non-nucleoside reverse transcriptase inhibitor; NRTI; N

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Simple and rapid determination of the enzyme kinetics of HIV-1 reverse transcriptase and anti-HIV-1 agents by a fluorescence based method

Keywords: HIV-1 RT; HIV-1 reverse transcriptase; NNRTI; non-nucleotide reverse transcriptase inhibitor; dTTP; deoxyribonucleotide triphosphate; HIV-1 reverse transcriptase; Fluorometric method; High-throughput screening; Anti-HIV agents; PicoGreen;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC

Keywords: HIV-1; Reverse transcriptase; NNRTI; RNase H; RNase H Inhibitor (RNHI); AZT resistance

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: Groebke reaction; Imidazo[1,2-a]pyridine; NNRTI; Reverse transcriptase; Antiretroviral; HIV;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and anti-HIV activity of 2′-deoxy-2′-fluoro-4′-C-ethynyl nucleoside analogs

Keywords: HIV-1; human immunodeficiency virus type-1; RT; reverse transcriptase; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; dN; 2′-deoxynucleoside; ddN; 2′,3′-dideoxynucleoside; AZT; zidovudine; SA

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Benzyl derivatives with broad potency against resistant mutant viruses

Keywords: HIV; Antiviral; NNRTI; Reverse transcriptase; Inhibitor; Aminopyrimidine; Viral mutants;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Similar Progression of Fibrosis Between HIV/HCV-Infected and HCV-Infected Patients: Analysis of Paired Liver Biopsy Samples

Keywords: Hepatitis C Disease Progression; Coinfection; Human Immunodeficiency Virus; ALP; alkaline phosphatase; APRI; AST to platelet ratio; AUC; area under the curve; HAART; highly active antiretroviral therapy; HAI; histologic activity index; HIV; human immunode

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Prevalence and Factors Associated With Liver Test Abnormalities Among Human Immunodeficiency Virus-Infected Persons

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; HAART; highly active antiretroviral therapy; HDL; high-density lipoprotein; HIV; human immunodeficiency virus; IQR; interquartile range; LDL; low-density lipoprotein; NA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

[d4U]-Spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase

Keywords: HIV inhibitors; Reverse-Transcriptase; NRTI; NNRTI; Double-drug; HI-236; d4T; Antiviral;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)

Keywords: NNRTI; Efavirenz; Nevirapine; Etravirine; Rilpivirine; Next generation NNRTI

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Pyrazole NNRTIs 4: Selection of UK-453,061 (lersivirine) as a Development Candidate

Keywords: HIV; RT; Reverse transcriptase; NNRTI; Lersivirine; AIDS

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Pyrazole NNRTIs 3: Optimisation of physicochemical properties

Keywords: HIV; Reverse transcriptase; NNRTI

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Pyrazole NNRTIs 1: Design and initial optimisation of a novel template

Keywords: HIV; Reverse transcriptase; NNRTI

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production

Keywords: HIV-1; Tryptophan repeat motif; Gag–Pol; RT dimerization; Gag processing; NNRTI; Efavirenz

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

QSAR models for 2-amino-6-arylsulfonylbenzonitriles and congeners HIV-1 reverse transcriptase inhibitors based on linear and nonlinear regression methods

Keywords: QSAR; HIV-1 non-nucleoside reverse transcriptase inhibitors; NNRTI; SVM; PPR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase—Structure–activity relationships and crystallographic analysis

Keywords: HIV-1 reverse transcriptase; NNRTI

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Orally bioavailable prodrugs of a BCS class 2 molecule, an inhibitor of HIV-1 reverse transcriptase

Keywords: Class 2 molecule; HIV-1 reverse transcriptase inhibitor; Prodrug; Pyridazinone; Oral bioavailability; Dissolution limiting pharmacokinetics; NNRTI; Hydroxymethyl derivatives

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors

Keywords: PDE4B2; Phosphodiesterase; HIV-1; Non-nucleoside reverse transcriptase inhibitor; NNRTI; Alkenyldiarylmethane; ADAM;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compound

Keywords: NNRTI; Aminonitrile; CSIC reaction; TSAO; ATSAO; Computational study;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Increased incidence of asthma in HIV-infected children treated with highly active antiretroviral therapy in the National Institutes of Health Women and Infants Transmission Study

Keywords: Pediatric HIV infection; CD4+ T cell-mediated induction of asthma; highly active antiretroviral therapy-produced immunoreconstitution; ART; Antiretroviral therapy; GEE; Generalized estimating equation; HAART; Highly active antiretroviral therapy; NNRT

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and antiviral activity of new dimeric inhibitors against HIV-1

Keywords: HIV-1; NNRTI; Synthesis; AZT; TNK-651; MKC-442; AZT; Sonogashira reaction; Click chemistry; NRTI; Nucleobase; Reverse transcriptase; Acetylene; d-norgestrel; Mutant; Virus; Drug-resistant; Efavirenz; Anti-viral activity; Uracil

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Keywords: NNRTI; HIV; Mutations

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and anti-HIV1 biological activity of novel 5″-ATSAO compounds

Keywords: Glycoaminonitrile; CSIC reaction; TSAO; ATSAO; NNRTI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

C-2-Aryl O-substituted HI-236 derivatives as non-nucleoside HIV-1 reverse-transcriptase inhibitors

Keywords: NNRTI; HI-236; AutoDock; Thiourea; HIV; Bifunctional inhibitors

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Monitoring the development of non-nucleoside reverse transcriptase inhibitor-associated resistant HIV-1 using an electrochemiluminescence-based reverse transcriptase polymerase assay

Keywords: ECL-based assay; RT polymerase assay; HIV-1; Resistance mutation; NNRTI

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase

Keywords: HIV; Non-nucleoside inhibitor; NNRTI; Reverse transcriptase; Drug resistance

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Nucleoside Reverse Transcriptase Inhibitors Are Able and Protease Inhibitors Unable to Induce the Tolerogenic Molecule HLA-G1 on Monocytes From HIV-1 Infected Patients

Keywords: HLA-G; HIV-1; AIDS; HAART; PI; NRTI; NNRTI

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine

Keywords: HIV-1; RT mutations; NNRTI; NRTI; Drug resistance

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Structure–activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity

Keywords: NNRTI; Pyridinone; IOPY; Anti-HIV

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: NNRTI; Scaffold hopping; Tertiary amide; Tertiary carbamate; Thio-tetrazole; Tetrazole thioacetanilide

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

HPLC–MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients

Keywords: TMC114; DRV; Protease inhibitors; NNRTI; Protein precipitation extraction; HPLC–MS; Quantification

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains

Keywords: NNRTI; HIV-1; Diarylpyrimidine (DAPY)

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides

Keywords: Microbicides; Sexual HIV transmission; NNRTI; Entry inhibitors; Dendritic cells; In vitro model

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1

Keywords: Antiviral; HIV; NNRTI; Pyrrolidinone

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase

Keywords: NNRTI; Anti-HIV; Structure-based drug design; Triazinylamine; 2-Pyrimidinylamine; Free energy perturbation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase

Keywords: NNRTI; Computer-aided drug design; Diarylamine; Anti-HIV drug; Thiazoylamine; Pyrimidinylamine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase

Keywords: NNRTI; Structure-based drug design; Anti-HIV drugs; Computer-aided drug design

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه