Synthesis and anti-HIV1 biological activity of novel 5″-ATSAO compounds

Aza TSAO-T derivatives bearing a substituted dihydroisothiazole dioxide ring with a phenyl group at 5″ position were prepared. Biological evaluation showed that phenyl group gives rise to a dramatical decrease of the inhibitory effect.

Aza TSAO-T derivatives bearing a substituted dihydroisothiazole dioxide ring with a phenyl group at 5″ position were prepared.Figure optionsDownload as PowerPoint slide