دانلود مقالات ISI درباره Nnrtis + ترجمه فارسی

Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1; NNRTIs; Diarylpyrimidines; Chiral resolution; Absolute configuration; Molecular docking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: HIV-1; NNRTIs; Piperidine; Triazine; AIDS; SAR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs

Keywords: HIV reverse transcriptase; NNRTIs; Heterocycle; Synthesis; Anti-HIV-1 activity; SAR; 1,2,4-Triazine; Structure-based bioisosterism strategy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach

Keywords: HIV reverse transcriptase; NNRTIs; Heterocycle; Synthesis; Anti-HIV-1 activity; SAR; Pyrazinylthioacetamide; Structure-based bioisosterism strategy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1; NNRTIs; 4,6-Diarylpyrimidines; Diarylbenzenes; Molecular modeling; SAR4,6-DAPY, 4,6-diarylpyrimidines; DABE, diarylbenzenes

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors

Keywords: HIV-1; NNRTIs; Piperidine; Triazine; Antiviral activity; SAR; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, biological activity and docking study of imidazol-5-one as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: Reverse transcriptase inhibitors; Docking; NNRTIs; HIV-1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, structure–activity relationships, and docking studies of N-phenylarylformamide derivatives (PAFAs) as non-nucleoside HIV reverse transcriptase inhibitors

Keywords: Anti-HIV activity; NNRTIs; Benzophenone derivatives; N-Phenylarylformamide; Structure–activity relationship

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Arylazolyl(azinyl)thioacetanilides. Part 10: Design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors

Keywords: HIV; NNRTIs; Heterocycle; Synthesis; Anti-HIV-1 activity; SAR; Imidazopyridine; Scaffold hopping;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents

Keywords: NNRTIs; S-DABOs; S-DACOs; Anti HIV-1 activity

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV; NNRTIs; Benzophenone derivatives; Benzhydrol; SAR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Complete inactivation of HIV-1 using photo-labeled non-nucleoside reverse transcriptase inhibitors

Keywords: Photo-inactivation; Reverse transcriptase; Intact viral structure; NNRTIs

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of Novel 2-(2-(2,4-Dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides As Potent HIV-1 inhibitors

Keywords: HIV; NNRTIs; 1,2,4-Triazole; Synthesis; Bioactivity; SAR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of naphthyl phenyl ethers (NPEs) as novel nonnucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1 reverse transcriptase; NNRTIs; NPEs; SAR; Anti-HIV activity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs

Keywords: HIV-1 reverse transcriptase; NNRTIs; CAPYs; DAPYs; Structure-activity relationships;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV; NNRTIs; Benzophenone derivatives; Naphthyl; SAR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs

Keywords: HIV-1 reverse transcriptase; NNRTIs; Diarylpyrimidines; CH(OH)-DAPYs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Lead optimization at C-2 and N-3 positions of thiazolidin-4-ones as HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: Thiazolidin-4-ones; Anti-HIV-1 activity; HIV-1 reverse transcriptase; NNRTIs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Rhodium(II) acetate-catalyzed stereoselective synthesis, SAR and anti-HIV activity of novel oxindoles bearing cyclopropane ring

Keywords: Oxindoles; Stereoselective synthesis; SAR; NNRTIs; Anti-HIV; MTT assay

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase

Keywords: HIV-1; HAART; Reverse transcriptase; NNRTIs; Resistance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1; AIDS; NNRTIs; S-DABOs; Anti-HIV-1 activity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs)

Keywords: HIV-1 reverse transcriptase; NNRTIs; Diarylpyridinones; Diarylpyridazinones; Diarylphthalazinones

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives

Keywords: NNRTIs; Anti-HIV drugs; Structure-based design; Free-energy calculations

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1

Keywords: NNRTIs; SAR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV

Keywords: HIV; NNRTIs; SAR; DAPYs;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors

Keywords: HIV-1; Reverse transcriptase; NNRTIs; DAPY

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

In search of a selective therapy of viral infections

Keywords: Double-stranded RNA; β-Interferon; Reverse transcriptase; NRTIs; NtRTIs; NNRTIs; Acyclovir; BVDU

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: HIV-1 RT; NNRTIs; S-DABO analogues; Docking

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy

Keywords: HIV-1 Reverse transcriptase; NNRTIs; DABPs; Molecular hybridization; SAR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs

Keywords: HIV-1; AIDS; NNRTIs; S-DABOs; Anti-HIV-1 activity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

1,2,3-Selenadiazole thioacetanilides: Synthesis and anti-HIV activity evaluation

Keywords: HIV-1; AIDS; NNRTIs; Selenadiazole; Anti-HIV-1 activity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1; AIDS; NNRTIs; Thiadiazole thioacetanilides; Heterocycle; Antiviral activity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice

Keywords: NNRTIs; RCT; ApoA-I; LDL receptor; Cholesterol efflux; HIV

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV-1; AIDS; NNRTIs; Imidazole thioacetanilides; Anti-HIV-1 activity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

QSAR studies for diarylpyrimidines against HIV-1 reverse transcriptase wild-type and mutant strains

Keywords: HIV-1 RT; NNRTIs; DAPYs; Hydrophobicity index; 2D-QSAR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies

Keywords: HIV-1; AIDS; NNRTIs; Thiadiazole thioacetanilides; Heterocycle; Antiviral activity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: NNRTIs; S-DABOs; Antiviral activity; In vitro; SAR; HIV-1; HIV-2CDI, 1,1′-carbonyldiimidazole; DABO, 2-alkoxyl-6-benzyl-3,4-dihydropyrimidin-4(3H)-ones; DDI, 2′,3′-dideoxyinosine; DMF, N,N-dimethylformamide; HEPT, 1-[(2-hydroxyethoxy)methyl]-6-(phenylsulf

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme–substrate complex

Keywords: HIV-1; NNRTIs; Drug resistance; Enzyme kinetics; AIDS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

CoMFA and CoMSIA studies on thiazolidin-4-one as anti-HIV-1 agents

Keywords: HIV-1RT; CoMFA; CoMSIA; NNRTIs; Thiazolidin-4-ones

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and anti-HIV studies of 2- and 3-adamantyl-substituted thiazolidin-4-ones

Keywords: Thiazolidin-4-ones; Adamantane derivatives; Anti-HIV activity; NNRTIs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Receptor- and ligand-based 3D-QSAR study for a series of non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: QSAR; CoMFA; CoMSIA; Docking; NNRTIs; HIV-1 reverse transcriptase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Keywords: HIV; NNRTIs; Thiadiazole thioacetanilides; 1,2,3-Thiadiazole; Synthesis; SAR

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies

Keywords: HIV-1; Reverse Transcriptase; Mutant; NNRTIs; S-DABOCs; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents

Keywords: 4-Thiazolidinones; Anti-HIV activity; HIV-1RT; NNRTIs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

Keywords: HIV; NNRTIs; SAR; S-DABOs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the “primer grip” region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants

Keywords: HIV-1; Reverse transcriptase; NNRTIs; Kinetics; Drug resistant; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and biological evaluation of N-acetyl-β-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro

Keywords: N-Acetyl-β-aryl-1,2-didehydroethylamine; β-Aryl-nitroolefin; NNRTIs; Anti-HIV-1 RT activity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Design, synthesis, and evaluation of 2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents

Keywords: 4-Thiazolidinones; Anti-HIV activity; HIV-1RT; NNRTIs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents

Keywords: 4-Thiazolidinones; Anti-HIV-1 activity; HIV-1 RT; NNRTIs; QSAR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies?

Keywords: HIV drug resistance; Microbicides; NNRTIs; NRTIs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه