Jagged 1 is necessary for normal mouse lens formation
Keywords: نشانه گیری; Lens development; Lens fiber differentiation; Aphakia; Notch signaling; Jagged1; Proliferation
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Position dependent responses to discontinuities in the retinal determination network
Keywords: نشانه گیری; Retinal determination; Sine oculis; Eyes absent; Dachshund; Groucho; Notch signaling; Drosophila; Compensatory proliferation; Gene regulatory networks; GRN;
Presenilin enhancer-2 (PSENEN), a component of the γ-secretase complex, is involved in adipocyte differentiation
Keywords: نشانه گیری; Presenilin enhancer-2; Adipocyte differentiation; γ-secretase complex genes; Notch signaling;
A systems biology approach to Down syndrome: Identification of Notch/Wnt dysregulation in a model of stem cells aging
Keywords: نشانه گیری; Trisomy 21; Hematopoietic; Neural; Progenitor; Senescence; Gene expression; Notch signaling; Aging; Stem cell;
Coordinating the timing of cardiac precursor development during gastrulation: A new role for Notch signaling
Keywords: نشانه گیری; Notch signaling; Esr9; Esr10; GATA4; Cardiogenesis; Heart field specification; Heart; Gastrulation; Xenopus laevis; Organogenesis;
Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity
Keywords: نشانه گیری; Notch signaling; Delta ligands; Neurogenesis; Retina; Spinal cord; Cell fate diversity
Estrogen receptor subtype β2 is involved in neuromast development in zebrafish (Danio rerio) larvae
Keywords: نشانه گیری; Estrogen receptor; Neuromast; Zebrafish; Notch signaling;
Essential roles for lines in mediating leg and antennal proximodistal patterning and generating a stable Notch signaling interface at segment borders
Keywords: نشانه گیری; Proximodistal patterning; Segmental patterning; Tarsus; Notch signaling; odd-skipped family genes; dAP-2; dachshund; bric-a-brac; apterous; Bar;
Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas
Keywords: نشانه گیری; Notch signaling; Pancreas development; Jagged1
A mutation in teg-4, which encodes a protein homologous to the SAP130 pre-mRNA splicing factor, disrupts the balance between proliferation and differentiation in the C. elegans germ line
Keywords: نشانه گیری; Germline development; Stem cells; Proliferation; Pre-mRNA splicing; Tumor; Meiotic entry; Notch signaling; teg-4; tag-203; SAP130
The HLH protein Extramacrochaetae is required for R7 cell and cone cell fates in the Drosophila eye
Keywords: نشانه گیری; Extramacrochaetae; Drosophila eye; Notch signaling; R7 cell; Eye development; Cell fate specification
Hopf bifurcation in the presomitic mesoderm during the mouse segmentation
Keywords: نشانه گیری; Dynamical modeling; Mouse segmentation; Notch signaling; Fgf signaling; bHLH gene oscillations
Complex interplay of three transcription factors in controlling the tormogen differentiation program of Drosophila mechanoreceptors
Keywords: نشانه گیری; Sox15; Su(H); Vvl; Tormogen; Socket cell; Notch signaling
Notch-regulated perineurium development from zebrafish spinal cord
Keywords: نشانه گیری; Perineurium; Radial glia; Notch signaling; BLBP; Spinal cord; Zebrafish
Correlative analyses of notch signaling with resveratrol-induced differentiation and apoptosis of human medulloblastoma cells
Keywords: نشانه گیری; Medulloblastoma; Resveratrol; Notch signaling; Differentiation; Apoptosis; γ-Seacretase inhibitors
Non-cell-autonomous inhibition of photoreceptor development by Dip3
Keywords: نشانه گیری; Dip3; MADF; BESS; Cell fate determination; Photoreceptor differentiation; Notch signaling;
Notch signaling and diseases: An evolutionary journey from a simple beginning to complex outcomes
Keywords: نشانه گیری; Notch signaling; Autoimmunity; Lymphomagenesis; Skin cancer
Human umbilical cord epithelial cells express Notch1: Implications for its epidermal-like differentiation
Keywords: نشانه گیری; Notch signaling; Differentiation; Epithelial cells; Umbilical cord
Pofut1 is required for the proper localization of the Notch receptor during mouse development
Keywords: نشانه گیری; Notch signaling; Heart development; Presomitic mesoderm; Endocytosis; Caveolin
Notch signaling regulates growth and differentiation in the mammalian lens
Keywords: نشانه گیری; Lens development; Notch signaling; Rbpj; Activated Notch; Growth; Cyclins; CKI
Cochlear stem/progenitor cells from a postnatal cochlea respond to Jagged1 and demonstrate that notch signaling promotes sphere formation and sensory potential
Keywords: نشانه گیری; Hearing loss; Hair cell regeneration; Stem/progenitor cells spheres; Jagged1; Notch signaling
Different downstream pathways for Notch signaling are required for gliogenic and chondrogenic specification of mouse mesencephalic neural crest cells
Keywords: نشانه گیری; Mesencephalic neural crest cells; Gliogenesis; Chondrogenesis; Notch signaling; Fibroblast growth factors; Deltex; RBP-J; Hairy enhancer of split; Mouse;
Notch signaling during larval and juvenile development in the polychaete annelid Capitella sp. I
Keywords: نشانه گیری; Segmentation; Chaetae; Notch signaling; Delta; hes; Polychaete; Capitella sp. I; Notch; Mesoderm; Annelid; Neurogenesis
Xenopus Suppressor of Hairless 2 is involved in the cell fate decision during gastrulation through the transcriptional regulation of Xoct25/91
Keywords: نشانه گیری; Suppressor of Hairless; Notch signaling; POU class V; Xoct25; Xoct91; Xbrachyury; Gastrulation; Xenopus laevis;
Expression of Jagged1 and its association with hepatitis B virus X protein in hepatocellular carcinoma
Keywords: نشانه گیری; Jagged1; Notch signaling; HCC; HBx
Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate
Keywords: نشانه گیری; Transgenic mice; Intestine development; Notch signaling; Stem cell; Cell fate; Enteroendocrine cell
Stem cell niches in mammals
Keywords: نشانه گیری; Stem cells; Tooth; Incisor; Hair; Bone; Notch signaling; Niches
Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C. elegans
Keywords: نشانه گیری; Notch signaling; C. elegans; LIN-12 receptor; LAG-2/Delta ligand; LIN-39/HOX; CEH-20/PBX/EXD; Vulval induction; Signaling crosstalk
Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation
Keywords: نشانه گیری; Somitogenesis; Mesp2; Mesp1; Notch signaling; Mouse genetics
The EGF-like Protein dlk1 Inhibits Notch Signaling and Potentiates Adipogenesis of Mesenchymal Cells
Keywords: نشانه گیری; EGF, epidermal growth factorDlk1; EGF-like proteins; adipogenesis; Notch signaling
Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells
Keywords: نشانه گیری; Mesencephalic neural crest cells; Chondrogenesis; Notch signaling; Fibroblast growth factors; Bone morphogenetic proteins; Mouse
Evidence for Notch signaling involvement in retinal regeneration of adult newt
Keywords: نشانه گیری; Notch signaling; Notch-1; DAPT; Retinal pigment epithelium; Retinal regeneration; Newt
Notch signaling links interactions between the C/EBP homolog slow border cells and the GILZ homolog bunched during cell migration
Keywords: نشانه گیری; Drosophila oogenesis; Notch signaling; TSC-22/GILZ family
The Notch signaling pathway in the cnidarian Hydra
Keywords: نشانه گیری; Notch signaling; Hydra; DAPT; Stem cells; Oogenesis;
Canonical Wnt signaling transiently stimulates proliferation and enhances neurogenesis in neonatal neural progenitor cultures
Keywords: نشانه گیری; Neurogenesis; Neural stem cells; β-Catenin; Wnt signaling; Notch signaling; Cell differentiation
In vitro expansion of long-term repopulating hematopoietic stem cells in the presence of immobilized Jagged-1 and early acting cytokines
Keywords: نشانه گیری; Jagged-1; Long-term repopulating ability stem cells; Notch signaling; Self-renewal; Serial BM transplantation; BFU-E; burst-forming units erythroid; BM; bone marrow; CFU-GM; colony-forming units granulocyte-macrophage; FL; Flk-2/Flt-3 ligand; HSC; hemat
Hath1 up-regulates gastric mucin gene expression in gastric cells
Keywords: نشانه گیری; Notch signaling; Hath1; MUC6; MUC5AC; Gastric cancer; Differentiation
Gene synthesis, expression, purification, and characterization of human Jagged-1 intracellular region
Keywords: نشانه گیری; Notch signaling; Synthetic gene; Intrinsically unstructured proteins; Circular dichroism; Tryptophan fluorescence; NMR; Limited proteolysis
Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells
Keywords: نشانه گیری; Arterial-venous differentiation; Endothelial cells; Notch signaling; Jagged1; Dll4; HERP; EphrinB2; EphB4; TGF-β; ALK1
Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish
Keywords: نشانه گیری; Mib, mind bomb; Snx5, sorting nexin 5; EEA1, early endosome antigen 1; HEK, human embryonic kidney; hpf, hours postfertilizationMind bomb; Sorting nexin 5; Notch signaling; Hematopoietic precursor cells; Endothelial precursor cells; Zebrafish
Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells
Keywords: نشانه گیری; PTH; PTH1R; Osteoblasts; Jagged1; Notch signaling; Protein kinase A; Osteoblastic–hematopoietic interactions
XMam1, Xenopus Mastermind1, induces neural gene expression in a Notch-independent manner
Keywords: نشانه گیری; XMam1; Mastermind; Neurogenesis; Notch signaling; Xenopus
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development
Keywords: نشانه گیری; Notch signaling; Embryonic stem cells; Cardiomyogenesis; Endothelial cells; Smooth muscle cells; Hematopoiesis; Mesodermal development
Neural stem cell properties of Müller glia in the mammalian retina: Regulation by Notch and Wnt signaling
Keywords: نشانه گیری; Müller cells; Stem cells; Retina; Progenitors; Notch signaling; Wnt signaling; Chemical injury
Roles of bHLH genes in neural stem cell differentiation
Keywords: نشانه گیری; bHLH genes; Neural stem cell; Neural development; Hes; Mash1; Math; Neurogenin; Notch signaling;
Function of RNA-binding protein Musashi-1 in stem cells
Keywords: نشانه گیری; Musashi; Translational regulation; Neural stem cell; Intestinal stem cell; Mammary gland stem cell; Notch signaling; Numb;
Genetics of Alagille syndrome
Keywords: نشانه گیری; Jagged1; Notch signaling; Pulmonic stenosis; Tetralogy of Fallot; Bile duct paucity; Cholestasis;
Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A
Keywords: نشانه گیری; Xenopus laevis; Activin; Notch signaling; Mesoderm induction; Loss of mesodermal competence; Smad phosphorylation;
Notch1 is essential for postnatal hair follicle development and homeostasis
Keywords: نشانه گیری; Notch signaling; Hair placode; Hair follicle; Hair cycle; Conditional gene targeting; Stem cells;
Cell type-specific and sexually dimorphic expression of transcription factor AP-2 in the adult mouse brain
Keywords: نشانه گیری; tfap2; Notch signaling; bed nucleus of the stria terminalis; olfactory mitral cell; locus coeruleus; solitary tract nucleus; AOB; accessory olfactory bulb; BST; bed nucleus of the stria terminalis (a.k.a. BNST); BSTLV; bed nucleus of the stria terminalis,