Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; ER, endoplasmic reticulum; MDa, Mega Dalton; ALPS, ArfGAP1 lipid packing sensorNuclear pore complex; Nuclear assembly; Cell cycle; Nucleoporin
مقالات ISI NPC، مجتمع منفرد هسته ای (ترجمه نشده)
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The Schizosaccharomyces pombe Hikeshi/Opi10 protein has similar biochemical functions to its human homolog but acts in different physiological contexts
Keywords: NPC، مجتمع منفرد هسته ای; EMM, Edinburgh minimal medium; GFP, green fluorescent protein; Imp-αs, importin-α family proteins; Imp-βs, importin-β family proteins; MAPK, mitogen activated protein kinase; NPC, nuclear pore complex; NTR, nucleocytoplasmic transport receptor; SAPK, stre
The role of Importin-βs in the maintenance and lineage commitment of mouse embryonic stem cells
Keywords: NPC، مجتمع منفرد هسته ای; Importin; Exportin; ESC; Germ layers; DifferentiationME, mesoendoderm; MEF, mouse embryonic fibroblast; mESCs, mouse embryonic stem cells; NE, neural ectoderm; NES, nuclear export signals; NLS, nuclear localization signals; NPC, nuclear pore complex; RA,
Transportin-1 and Transportin-2: Protein nuclear import and beyond
Keywords: NPC، مجتمع منفرد هسته ای; hnRNP, heterogeneous ribonucleoprotein; NES, nuclear export signal; NLS, nuclear localization signal; NPC, nuclear pore complex; TRN-1, Transportin-1; TRN-2, Transportin-2Transportin; Importins; Karyopherins; Nuclear import; Nucleo-cytoplasmic transport;
The genetic basis of triple A (Allgrove) syndrome in a Greek family
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; UTR, untranslated regionTriple A/Allgrove syndrome; AAAS gene; Nucleoporin ALADIN; Addison's disease; Achalasia; Alacrima
Nucleoporin Nup98 mediates galectin-3 nuclear-cytoplasmic trafficking
Keywords: NPC، مجتمع منفرد هسته ای; APC, adenomatous polyposis coli; CK1, casein kinase 1; NPC, nuclear pore complex; Nup, nucleoporin; RNAi, RNA interference; siRNA, small interfering RNA; Tpr, translocated promoter regionNucleoporin; Nuclear pore complex; Galectin-3; Nuclear transport; Ca
Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; CTD, C-terminal domain; HIV-1, human immunodeficiency virus-1; CypA, cyclophilin A; β-ME, β-mercaptoethanol; SSRL, Stanford Synchrotron Radiation Lightsource; PDB, Protein Data Bank; ITC, isothermal titration calorimetry; PBS, p
Structural features of transversal barrier in central channel of nuclear pore complex
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; FG, fenylalanine–glycine; Nup, nucleoporinNuclear pore complex; Central channel; Transversal barrier; Transmission electron microscopy
Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity
Keywords: NPC، مجتمع منفرد هسته ای; ABCA1, ATP-binding cassette transporter A1; ER, Endoplasmic reticulum; Exo70, Exocyst complex protein of 70 kDa; GST, Glutathione-S-transferase; NPC, Nuclear Pore Complex; NUP62, Nucleoporin p62; ORP, OSBP-related protein; OSBP, Oxysterol-binding protein;
The Structure of the NXF2/NXT1 Heterodimeric Complex Reveals the Combined Specificity and Versatility of the NTF2-Like Fold
Keywords: NPC، مجتمع منفرد هسته ای; Nup, nucleoporin; NPC, nuclear pore complex; NTF2-like, nuclear transport factor 2-like; hsNXF1, human NXF1; LRR, leucine-rich repeat; UBA, ubiquitin-associated; RFP, red fluorescent protein; EGFP, enhanced green fluorescent protein; SeMet, selenomethioni
Lighting up the nuclear pore complex
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; NE, nuclear envelope; Nup, nucleoporin; OSTR, optical single transporter recording; NTR, nuclear transport receptor; Kap, karyopherin; NLS, nuclear localization sequence; NES, nuclear export sequence; GEF, guanine nucleotide exc
Single molecule studies of nucleocytoplasmic transport
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; Nup, nucleoporin; NE, nuclear envelope; SMF, single molecule fluorescence; NTR, nuclear transport receptor; S/N, signal-to-noise ratio; fps, frames per second; smFRET, single molecule fluorescence resonance energy transferNuclea
The importin β binding domain as a master regulator of nucleocytoplasmic transport
Keywords: NPC، مجتمع منفرد هسته ای; IBB, Importin β binding domain; NLS, nuclear localization sequence; NPC, nuclear pore complex; Nuclear import; Karyopherins; Importin β; Importin α; Ran
Expression of nucleocytoplasmic transport machinery: Clues to regulation of spermatogenic development
Keywords: NPC، مجتمع منفرد هسته ای; NE, Nuclear envelope; NPC, Nuclear pore complex; NUPs, Nucleoporins; NLS, Nuclear localisation signal; cNLS, Classical nuclear localisation signal; NES, Nuclear export signal; IBB, Importin beta binding; RAN-GTP, RAN, in its GTP bound form; RAN-GDP, RAN,
Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis
Keywords: NPC، مجتمع منفرد هسته ای; NE, nuclear envelope; NPC, nuclear pore complex; IMP, importin; IBB, IMPβ-binding domain; ARM, armadillo; NLS, nuclear localization signal; NES, nuclear export signal; CAS, cellular apoptosis susceptibility protein; Ran, Ras-related nuclear protein; RanBP
Structural Analysis of a Metazoan Nuclear Pore Complex Reveals a Fused Concentric Ring Architecture
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; NE, nuclear envelope; 3D, three-dimensional; EM, electron microscopy; SR, spoke–ring; CR, cytoplasmic ring; NR, nuclear ring; NM, nuclear membrane; INM, inner nuclear membrane; ONM, outer nuclear membrane; Nup, nucleoporin; FG-r
Alternative transcripts expressed by small bristles, the Drosophila melanogaster nxf1 gene
Keywords: NPC، مجتمع منفرد هسته ای; CPE, cytoplasmic polyadenylation element; CTE, constitutive transport element; LRR, leucine-rich repeat; NES, nuclear export signal; NLS, nuclear localization signal; NMD, nonsense-mediated mRNA decay; NPC, nuclear pore complex; NTF, nuclear transport fac
Exclusion of mRNPs and ribosomal particles from a thin zone beneath the nuclear envelope revealed upon inhibition of transport
Keywords: NPC، مجتمع منفرد هسته ای; BR, Balbiani ring; NPC, nuclear pore complex; mRNP, messenger ribonucleoprotein; rRNP, ribosomal particle; WGA, wheat germ agglutininNucleocytoplasmic transport; Nuclear pore complex; Nuclear basket; Messenger RNA export; Messenger RNP particles; Ribosoma
Molecular Basis for the Recognition of Phosphorylated STAT1 by Importin α5
Keywords: NPC، مجتمع منفرد هسته ای; NLS, nuclear localization signal; pSTAT1, phosphorylated STAT1; ARM, Armadillo; uSTAT1, unphosphorylated STAT1; dsDNA, double-stranded DNA; NPC, nuclear pore complex; cNLS, classical NLS; IBB, importin β binding; dsNLS, dimer-specific NLS; EBNA-1, Epstein
Functional Interaction of the Ras Effector RASSF5 with the Tyrosine Kinase Lck: Critical Role in Nucleocytoplasmic Transport and Cell Cycle Regulation
Keywords: NPC، مجتمع منفرد هسته ای; NES, nuclear export signal; SH3, Src homology 3; NLS, nuclear localization signal; LMB, leptomycin B; SH2, Src homology 2; NPC, nuclear pore complex; CHX, cycloheximide; GFP, green fluorescent protein; GST, glutathione S-transferase; DMEM, Dulbecco's modi
The nuclear pore complex protein ALADIN is anchored via NDC1 but not via POM121 and GP210 in the nuclear envelope
Keywords: NPC، مجتمع منفرد هسته ای; FRET, fluorescence resonance energy transfer; FLIM, fluorescence lifetime imaging microscopy; NPC, nuclear pore complex; NUP, nucleoporin; GFP, green fluorescent protein; CFP, cyan fluorescent proteinALADIN; NDC1; Nuclear pore complex; Nucleoporin; Triple
Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import
Keywords: NPC، مجتمع منفرد هسته ای; LDL, Low density lipoprotein; oxLDL, oxidized low density lipoprotein; naLDL, native low density lipoprotein; VSMC, vascular smooth muscle cells; NPI, nuclear protein import; NPC, nuclear pore complex; MAPKs, mitogen-activated protein kinases; PCNA, Proli
Evolution of specificity in the eukaryotic endomembrane system
Keywords: NPC، مجتمع منفرد هسته ای; LCEA, last Common Eukaryotic Ancestor; SM, Sec1/Munc18; GAP, GTPase-activating protein; GEF, guanine exchange factor; TGN, trans-Golgi network; AP, adaptin; NPC, nuclear pore complex; MVB, multivesicular body; ENTH, epsin N-terminal homology; REP, Rab esc
Nuclear pore proteins and cancer
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; cNLS, classical nuclear localization signal; NES, nuclear export signal; FG, phenylalanine-glycine; FxFG, phenylalanine-any amino acid-phenylalanine-glycine; GLFG, glycine-leucine-phenylalanine-glycine; AA, amino acidNuclear por
Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; EM, electron microscopy; Nup, nucleoporin; NTR, nuclear transport receptor; ZnF, zinc fingernuclear pore complex; Nup153; Ran; zinc fingers; crystallography
Insertion of nuclear factor-κB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells
Keywords: NPC، مجتمع منفرد هسته ای; pDNA, plasmid DNA; NF-κB, nuclear factor κB; NPC, nuclear pore complex; ROS, reactive oxygen species; CMV, cytomegalovirus; PMS, phenazine methosulfateGene transfer; Transcription factor; Nuclear factor-κB; Reactive oxygen species; Colon carcinoma cell; N
Two distinct human POM121 genes: Requirement for the formation of nuclear pore complexes
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; NE, nuclear envelope; Nup, nucleoporin; RT-PCR, reverse transcriptase-polymerase chain reaction; siRNA, small interfering RNANuclear pore complex; Pom121; Nuclear structure; RNAi; Segmental-duplication
The maximal size of protein to diffuse through the nuclear pore is larger than 60 kDa
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; ERK2, extracellular signal-regulated kinase 2; PDK1, 3′-phosphoinositide-dependent kinase; aa, amino acid(s); NLS, nuclear localization signal; NES, nuclear export signalNuclear pore; Protein nuclear translocation; Diffusion lim
What can Caenorhabditis elegans tell us about the nuclear envelope?
Keywords: NPC، مجتمع منفرد هسته ای; NE, nuclear envelope; INM, inner nuclear membrane; ONM, outer nuclear membrane; PS, perinuclear space; NPC, nuclear pore complex; NEBD, nuclear envelope breakdown; ER, endoplasmic reticulumNuclear envelope; Nuclear pore complex; Chromatin; Nuclear lamina;
Domain Topology of the p62 Complex Within the 3-D Architecture of the Nuclear Pore Complex
Keywords: NPC، مجتمع منفرد هسته ای; NE, nuclear envelope; NPC, nuclear pore complex; FG, phenylalanine-glycine; EM, electron microscopy; GFP, green fluorescent proteinnuclear pore complex; p62 complex; nucleoporins; FG-repeats; immuno-electron microscopy
The arginine methyltransferase Rmt2 is enriched in the nucleus and co-purifies with the nuclear porins Nup49, Nup57 and Nup100
Keywords: NPC، مجتمع منفرد هسته ای; PRMT, protein arginine methyltransferase; NPC, nuclear pore complex; TAP, tandem affinity purificationRmt2; Protein arginine methyltransferase; Nuclear envelope; NPC; Yeast; MYO1
Proteins that associate with lamins: Many faces, many functions
Keywords: NPC، مجتمع منفرد هسته ای; Crx, cone-rod homeobox; gcl, germ cell-less; LAP, lamin-associated polypeptide; NE, nuclear envelope; ER, endoplasmic reticulum; INM, inner nuclear membrane; ONM, outer nuclear membrane; NPC, nuclear pore complex; LEM domain, LAP2-Emerin-MAN1 domain; Lmo7
Significant Proportions of Nuclear Transport Proteins with Reduced Intracellular Mobilities Resolved by Fluorescence Correlation Spectroscopy
Keywords: NPC، مجتمع منفرد هسته ای; ANOVA, analysis of variance; APC, allophycocyanin; CAS, cellular apoptosis susceptibility gene; FCS, fluorescence correlation spectroscopy; NLS, nuclear localization signal; NPC, nuclear pore complex; NTF2, nuclear transport factor 2; Ran, Ras-related nuc
Association of Nuclear Pore FG-repeat Domains to NTF2 Import and Export Complexes
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; RanGAP, RanGTPase activating protein; nup/Nup, nucleoporin; RMSD, root mean square deviationnuclear pore complex; NTF2; FG-Nups/FG repeats; nuclear transport; transport receptor/transport factor/transport complex
Aberrant localization of importin α1 in hippocampal neurons in Alzheimer disease
Keywords: NPC، مجتمع منفرد هسته ای; AD, Alzheimer disease; APTX, aprataxin; DAB, 3-3′-diaminobenzidine; GVD, granular vacuolar degeneration; NFT, neurofibrillary tangles; NGS, normal goat serum; NLS, nuclear localization signal; NPC, nuclear pore complex; NTF2, nuclear transport factor 2; P
Mechanism of the stress-induced collapse of the Ran distribution
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; NLS, nuclear localization signal; NES, nuclear export signal; CAS, cellular apoptosis susceptibility; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GST, glutathione S-transferase; GFP, green fluorescent protein; NEM, N-ethylm
The Crystal Structure of Mouse Nup35 Reveals Atypical RNP Motifs and Novel Homodimerization of the RRM Domain
Keywords: NPC، مجتمع منفرد هسته ای; RRM, RNA-recognition motif; RNP, ribonucleoprotein; Nup, nucleoporin; NPC, nuclear pore complex; NE, nuclear envelope; kaps, karyopherins; FG, Phe-Gly; RBD, RNA-binding domain; PIE, polyadenylation inhibition element; PABP, polyadenylate-binding protein;
Changes in Nucleoporin Domain Topology in Response to Chemical Effectors
Keywords: NPC، مجتمع منفرد هسته ای; NPC, nuclear pore complex; NE, nuclear envelope; Nup, nucleoporin; AFM, atomic force microscopynuclear pore complex; nuclear transport; calcium; Nup153; Nup214
Nuclear Transport of Trimeric Assembly Intermediates Exerts a Morphogenetic Control on the Icosahedral Parvovirus Capsid
Keywords: NPC، مجتمع منفرد هسته ای; capsid assembly; trimeric intermediates; nuclear transport; parvovirus morphogenesisMVM, parvovirus minute virus of mice; NPC, nuclear pore complex; NE, nuclear envelope; NLS, nuclear localization signal; NES, nuclear export signal; DMS, dimethyl suberimi
Coordinated intracellular translocation of phosphoinositide-specific phospholipase C-δ with the cell cycle
Keywords: NPC، مجتمع منفرد هسته ای; DG, diacylglycerol; LMB, leptomycin B; NES, nuclear export signal; NLS, nuclear localization signal; NPC, nuclear pore complex; PH, pleckstrin homology; PHD, plant homeodomain; PI, phosphoinositide; PI3K, PtdIns 3-kinase; PKC, protein kinase C; PLC, phosp